Abstract: A system for computing devices includes a central processing unit (CPU that is configured to perform in a plurality of power modes, each power mode being pre-defined to have a different code-execution performance capability than remaining ones of the plurality of power modes. The system further includes a sampling peripheral, an electrical output, and a memory device. The memory device is configured to select and execute a specific module from the plurality of modules based on the context-identifying input triggering the specific module. If triggered, each module is executed to receive the context-identifying input from the sampling peripheral, and to operate the CPU in a dedicated power mode of the plurality of power modes.

Abstract: A system for computing devices includes a central processing unit (CPU that is configured to perform in a plurality of power modes, each power mode being pre-defined to have a different code-execution performance capability than remaining ones of the plurality of power modes. The system further includes a sampling peripheral, an electrical output, and a memory device. The memory device is configured to select and execute a specific module from the plurality of modules based on the context-identifying input triggering the specific module. If triggered, each module is executed to receive the context-identifying input from the sampling peripheral, and to operate the CPU in a dedicated power mode of the plurality of power modes.

Abstract: This disclosure provides systems, methods, and apparatus related to thin free-standing oxide membranes. In one aspect, a method includes providing a substrate. The substrate defines a hole having a diameter of about 500 nanometers to 5000 nanometers. A layer of metal is deposited on the substrate. A supporting layer is deposited on the layer of metal. A first side of the supporting layer is the side that is disposed on the layer of metal. A metal oxide layer is deposited on the first side of the supporting layer and on the substrate. In some implementations, the method further includes removing the supporting layer.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.

Abstract: A smart syringe system and method are provided. The system includes a smart syringe and an external device. The syringe obtains data of a dose administered to a patient and wirelessly transmit the data to the external device. Alternately, the external device obtains the data via an image of the syringe. The external device may execute an application configured to process the data and display information of the dose.

Abstract: A system for computing devices includes a central processing unit (CPU that is configured to perform in a plurality of power modes, each power mode being pre-defined to have a different code-execution performance capability than remaining ones of the plurality of power modes. The system further includes a sampling peripheral, an electrical output, and a memory device. The memory device is configured to select and execute a specific module from the plurality of modules based on the context-identifying input triggering the specific module. If triggered, each module is executed to receive the context-identifying input from the sampling peripheral, and to operate the CPU in a dedicated power mode of the plurality of power modes.

Abstract: The present invention relates to a group of compounds derived from resveratrol having as substituents at least one silyl group which, in turn, can be substituted by different groups. The invention also relates to the therapeutic use of these compounds in inflammatory, neurological, and neurodegenerative diseases.

Abstract: This disclosure provides systems, methods, and apparatus related to thin free-standing oxide membranes. In one aspect, a method includes providing a substrate. The substrate defines a hole having a diameter of about 500 nanometers to 5000 nanometers. A layer of metal is deposited on the substrate. A supporting layer is deposited on the layer of metal. A first side of the supporting layer is the side that is disposed on the layer of metal. A metal oxide layer is deposited on the first side of the supporting layer and on the substrate. In some implementations, the method further includes removing the supporting layer.

Abstract: A therapeutic use of acylated piceid derivative compounds in ocular pathologies, in particular retinitis pigmentosa and in age-related macular degeneration, inter alia. A method of treating and/or preventing ocular pathologies, wherein the method includes administering to a patient in need of treatment a therapeutically effective amount of a compound of general formula (I) or any of its isomers, their pharmaceutically acceptable salts, esters, tautomers, polymorphs, or hydrates.

Abstract: The present invention relates to the therapeutic use of acylated piceid derivative compounds in ocular pathologies, in particular retinitis pigmentosa and in age-related macular degeneration.

Abstract: The present disclosure relates generally to the analysis of immune checkpoint proteins involved in cancer. In particular, the present disclosure provides material and methods for determining abundance ratios of various immune checkpoint proteins (e.g., PD-1, PD-L1, and PD-L2) present in a biospecimen sample based on quantification of peak area using mass spectrometry analysis. The methods disclosed herein provide an alternative platform for diagnosing and treating cancer, especially in cases limited by ineffective antibody recognition.

Abstract: An implant-supported dental prosthesis, removal device for automatically removing the prosthesis, attachment piece for attaching the prosthesis to implants and an attachment bar for attaching the prosthesis to implants. The prosthesis comprises a compartment with a spacing member that can be actuated through a side opening by means of the device, for automatically removing the prosthesis. The device comprises a head with a first plunger configured for being introduced in the compartment and moving the first plunger in both directions to move the first plunger out when the spacer moves, causing removing the prosthesis, and when the first plunger moves in the opposite direction the head is extracted from the compartment. The attachment piece and bar for attaching the prosthesis respectively comprise a projection and a step to make it easier to remove the prosthesis.

Abstract: Systems and methods are provided for modeling fluid flow in a turbomachine. A specification of a system including first and second blade rows is received. A wake profile from the first blade row is imposed on the second blade row to approximate an influence of the first blade row on the second blade row. Governing flow equations for the fluid flow in the second blade row are transformed in time. Flow variables of the transformed governing flow equations are represented as a Fourier series, and the Fourier series representation is substituted into the transformed governing flow equations to obtain a modified form of the transformed governing flow equations. A pseudo-time term is introduced into the modified form of the transformed governing flow equations. The modified form of the transformed governing flow equations is solved using the steady-state solution method to model the fluid flow in the second blade row.

Abstract: Systems and methods are provided for modeling fluid flow in a turbomachine. A specification of a system including at least a stator and a rotor of a turbomachine is received. The stator is coupled to the rotor via a profile-transformation (PT) interface. A flow profile for fluid flow across the PT interface is expanded or compressed based on a pitch ratio between the stator and the rotor. Flow variables of governing flow equations for the fluid flow in the system are represented as a Fourier series with spatially-varying Fourier coefficients. The Fourier series representation is substituted into the governing flow equations to obtain a modified form of the governing flow equations. The modified form of the governing flow equations is solved using a steady-state solution method to model the fluid flow in the system. The modeling utilizes an implicit solution discretization across the PT interface.

Abstract: The invention relates to a plasma screen that fits different shapes and measurements, which is foldable, pliable and impermeable, with self-adhesive material for placing on any surface. The device is small, slim, autonomous (does not need to be connected to electricity), pliable, foldable (can be folded), impermeable (resistant to water and inclement weather), easy to stick on any surface and very low cost. The device is interactive and comprises a user terminal (1) that brings together all the parts of the device, the terminal taking the form of different-shaped plastic stickers and containing a foldable plasma screen (2) that covers the circumference of same and transmits images and video. All the parts of the device are connected, by means of small cables (9), to an integrated microcomputer (3) with a processor that contains a computer program, a formula and algorithms that allow information processing and transmission and GPS location.

Abstract: Systems and methods are provided for modeling fluid flow in a turbomachine. A specification of a system is received. The system includes multiple passages, where the multiple passages include at least an inlet guide vane, a rotor, and a stator. A computational grid is generated with a processing system based on the received specification. Governing flow equations for the system are transformed based on inclination parameters, where each passage of the system has an associated inclination parameter. A rotational velocity of rotating passages included in the system is specified, and a time-step for stationary passages included in the system is specified. Time-steps for the rotating passages included in the system are computed, where the time-steps are computed based on pitch-ratios for adjacent passages of the system. A solution for the system is advanced in time by solving the transformed governing flow equations across the computational grid using computer-based numerical calculations.

Abstract: The present invention relates to a group of compounds derived from resveratrol having as substituents at least one silyl group which, in turn, can be substituted by different groups. The invention also relates to the therapeutic use of these compounds in inflammatory, neurological, and neurodegenerative diseases.

Abstract: The present invention relates to the therapeutic use of acylated piceid derivative compounds in ocular pathologies, in particular retinitis pigmentosa and in age-related macular degeneration.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device is a wearable automatic injector configured to be worn on the patient's skin. A delivery device of the present disclosure allows a user or patient to view the status of a container. For example, a delivery device of the present disclosure provides a simple and effective visual means of displaying fill confirmation and delivery confirmation.