Abstract: The invention provides non-invasive assays to reliably identify women who have or are predisposed to developing preeclampsia (PE). The method comprises measuring a level of annexin A2 (ANXA2) in a test sample obtained of a subject; and identifying the subject as having preeclampsia or at an increased risk of developing preeclampsia when the level of ANXA2 in the test sample is decreased in relation to a control sample. Methods to treat subject identified as having PE or at an increased risk of developing preeclampsia are also provided.

Abstract: A method and device for cooling a turboengine rotor. A blade member includes a platform having a hot gas side and a coolant side. An airfoil is on the platform hot gas side and a blade foot section is on the platform coolant side. The blade foot section includes a blade shank and a blade root. The blade shank extends from the platform coolant side and is interposed between the blade root and the platform coolant side. The blade root includes root fixation features and is received by a fixation feature of a rotor shaft. A first fluid flows along the rotor front face and into a cavity of the blade shank and a second fluid flows within the blade shank cavity. The first fluid flow is relatively colder than the second fluid flow and a combined shank cavity fluid flow is formed inside the blade shank cavity.

Abstract: A method is disclosed for cooling a gas turbine having a turbine, wherein a rotor, which rotates about a machine axis, carries a plurality of rotating blades, which are mounted by blade roots and extend with their airfoils into a hot gas path of the gas turbine. The rotor is concentrically surrounded by a turbine vane carrier carrying a plurality of stationary vanes, whereby the rotating blades and the stationary vanes are arranged in alternating rows in axial direction. An extended lifetime with external cooling is achieved by providing first and second cooling systems for the turbine.

Abstract: A gas turbine includes a rotor concentrically surrounded by a casing, with an annular hot gas channel axially extending between the rotor and the casing. The rotor includes a plurality of blades arranged annularly on the rotor. Each of the blades is mounted with a root in a respective axial slot on a rim of the rotor radially extending with an airfoil into the hot gas channel and adjoining with an axially oriented root surface to an annular rim cavity. A cooling device is provided at the root of each blade to receive cooling air injected into the rim cavity through stationary injectors. An optimized cooling is achieved by providing an essentially plane root surface and the cooling device includes a scoop for capturing and redirecting at least part of the injected cooling air, which scoop is a recess with respect to the root surface.

Abstract: The invention concerns a turbine for a gas turbine comprising a blade, a vane and an abradable lip attached to the blade or to the vane, wherein the blade and the vane are separated by a gap and the abradable lip extends part of the distance across the gap. Embodiments include the addition of an abrasive layer attached on the other side of the gap from the abradable lip. A method of manufacturing is also described.

Abstract: Disclosed is an engine, the engine having a compressor, an expansion machine, and a shaft, the shaft having a direction of rotation. The engine includes a compressed fluid main flow path, a flow divider arranged at and fluidly connected to the compressed fluid main flow path, and a duct fluidly connecting the flow divider and components of the expansion machine. The duct is arranged such that, when the engine is operated, a fluid is guided through the duct from the flow divider towards the expansion machine components. A flow deflector device is arranged within a flow path and configured to deflect and thereby accelerate a flow therethrough directed form the flow divider towards the expansion machine components in a tangential direction, wherein the deflection can be effected into the shaft direction of rotation.

Abstract: The present disclosure generally relates to a rotor assembly, and in particular relates to an improved rotor heat shield which provides an innovative configuration for securing the same to the rotor assembly. The rotor heat shield element is secured to the rotor assembly in correspondence of the groove in which it is inserted. Embodiments of the present disclosure can allow the removal of current fixation features on heat shields and blades. Furthermore, since the heat shield is no longer connected to a blade but directly to the rotor assembly, there is more freedom in selecting the number of heat shield elements to be provided to form the circumferential heat shield.

Abstract: An engine casing element comprises at least one clearance control cavity, the clearance control cavity being delimited by a clearance control cavity inner wall and having a clearance control cavity longitudinal extent. At least one insert member is arranged inside the clearance control cavity. The insert member is arranged and configured to effect at least one of a flow guide function and a heat transfer enhancement function.

Abstract: The present invention relates to a rotor assembly for a rotary machine such as a gas turbine. The present solution provides a sealing wire located inside a groove engraved in the rotor body. The sealing wire is responsive to radial centrifugal forces acting during normal operation of the machine, and moves radially in the groove until a sealing configuration is achieved such to prevent damaging hot leakage towards machine components.

Abstract: The invention relates to a rotor shaft adapted to rotate about a rotor axis thereof. The rotor shaft includes a rotor cavity configured concentrically or quasi-concentrically to the rotor axis inside the rotor shaft, and a plurality of cooling bores extending radially or quasi-radially outward from the inside to an outside of the rotor shaft. Each cooling bore having a bore inlet location and a distal bore outlet portion, the respective bore inlet location being adapted to abut on the rotor cavity. At least one side or part-side of the cooling bore inlet location is provided with an asymmetric edge fillet in order to maximize the wall thickness between two adjacent cooling bores.

Abstract: The invention pertains to a seal system for a passage between a turbine stator and a turbine rotor, including: a first arm extending radially outwards from the turbine rotor and toward the first seal arranged on the stator, and terminating short of the first seal thereby creating a first gap between the first seal and the first arm. The seal system further includes a second seal arranged on the turbine stator, and a second arm extending axially from the turbine rotor towards the second seal base, and terminating short of the second seal thereby creating a second gap between the second seal and the second arm. The invention further refers to a gas turbine including such a seal system.

Abstract: The use of a dopamine agonist in the manufacture of a medicament for the treatment or prevention of endometriosis.

Abstract: A blade is provided and includes a platform and a root configured to be connected to a blade carrier. Airfoil portions extend from opposite sides of the platform. Each airfoil portion defines an operating surface being the surface facing the other airfoil portion. An operating surface of one of the airfoil portions defines a suction side and the other operating surface of the other airfoil portion defines a pressure side.

Abstract: A blade arrangement is provided for a gas turbine, in which blade leaves, having a leading edge and a trailing edge and also a pressure side and a suction side, are assembled sealingly with platforms configured as separate components. A peripheral sealing arrangement is provided between the blade leaves and the associated platforms, which seals off an interspace between the blade leaves and platforms against hot gas flowing around the blade leaves. A directed site-dependent supply of cooling air for purging the sealing arrangement is provided on a side of the sealing arrangement which faces away from the hot gas. A method of operating the above blade arrangement is also provided. The method includes supplying cooling air for purging the sealing arrangement at a pressure which decreases from the leading edge of the blade leaves to the trailing edge.

Abstract: A gas turbine (1) includes a combustion chamber (2) followed by a stator airfoil row (4) defining a plurality of guide vanes and separated by the combustion chamber (2) by a first gap (5), and a rotor airfoil row (6) separated by the stator airfoil row (4) by a second gap (7). The stator airfoils (15) of the stator airfoil row (4) are connected to guide vane boxes (17) collecting a cooling fluid (A) and injecting it through nozzles (20) in the second gap (7) to make it to enter rotor airfoil inlets (23). The guide vane boxes (23) are provided with passages (30) connecting a zone (31) upstream of the guide vane boxes (17) to a zone (32) of the second gap (7) downstream of the guide vane boxes (32). Moreover, the mouths (3) of the passages (30) facing the rotor airfoil row (6) are closer to a hot gases path than the nozzles (20).

Abstract: The use of a dopamine agonist in the manufacture of a medicament for the treatment or prevention of endometriosis.

Abstract: The invention refers to a fluid seal arrangement for constricting a leakage flow directed through a leakage gap bordered by a rotational and a stationary component including at least one nozzle opening in the rotating and/or stationary component facing towards the rotating or stationary component of an opposite side of the leakage gap respectively in order for injecting a liquid or gaseous fluid flow through the nozzle opening into the leakage gap. The at least one nozzle opening is fluidly connected to a cooling channel inside said rotating and/or stationary component, so that said fluid flow emanating at the nozzle opening consists of a cooling fluid of the rotating and/or stationary component exclusively.

Abstract: The disclosure pertains to a turbine with a gas turbine blade and a rotor heat shield for separating a space region through which hot working medium flows from a space region inside a rotor arrangement of the turbine. The rotor heat shield includes a platform which forms an axial heat shield section and which is arranged substantially parallel to the surface of a rotor and a radial heat shield section at the upstream end of the axial heat shield section, which is extending in a direction away from the surface of the axial heat shield section towards the hot gas. Further the turbine comprises a blade rear cavity which is delimited by the downstream end of the platform and/or the downstream end of the blade foot, the radial heat shield section. The disclosure further refers to a gas turbine blade and a rotor heat shield designed for such a turbine.

Abstract: The use of a dopamine agonist in the manufacture of a medicament for the treatment or prevention of endometriosis.

Abstract: A turbine blade is provided having an airfoil and a platform manufactured in two separate pieces, which are joined together. The blade includes a seal, which is a mechanically decoupled seal, interposed between the airfoil and platform in a position closer to a hot gases path than a joint.