Abstract: A pharmaceutical composition comprising quinagolide for the treatment and/or prevention of endometriosis.

Abstract: A labyrinth seal is provided for sealing the annular interspace between the rotor and the stator of a steam turbine or gas turbine. The labyrinth seal includes a multiplicity of sealing strips which are arranged in series in the axial direction and fastened on the stator and project into the interspace. The sealing strips interact, with sealing effect, with rotor-side sealing elements which are arranged in a staggered manner. An improved sealing effect is achieved by the sealing strips in the cold installed state being offset in relation to a symmetrical position, wherein the offset has the reverse direction and the same amount as the distance by which the sealing strip is displaced relative to adjacent rotor-side sealing elements as a result of thermal expansions of the stationary and rotating components and support structure when being heated from the cold installed state to a hot steady-state operating condition.

Abstract: A gas turbine includes a rotor concentrically surrounded by a casing, with an annular hot gas channel axially extending between the rotor and the casing. The rotor is equipped with a plurality of blades, which are arranged on the rotor in an annular fashion. Each of the blades is mounted with a root in a respective axial slot on a rim of the rotor radially extending with an airfoil into said hot gas channel and adjoining with an axially oriented root surface to an annular rim cavity. Cooling means are provided at the root of each of said blades to receive cooling air being injected into said rim cavity through stationary injecting means. An optimized cooling is achieved by providing the root surface to be an essentially plane surface and the cooling means including a scoop for capturing and redirecting at least part of the injected cooling air, which scoop is designed as a recess with respect to the root surface.

Abstract: A method and a cooling system for cooling blades of at least one blade row in a rotary flow machine includes an axial flow channel which is radially limited on the inside by a rotor unit and at the outside by at least one stationary component, the blades are arranged at the rotary unit and provide a shrouded blade tip facing radially to said stationary component. Pressurized cooling air is fed through from radially outside towards the tip of each of said blades in the at least one blade row, and the pressurized cooling air enters the blades through at least one opening at the shrouded blades' tip.

Abstract: The invention relates to a non-invasive diagnostic method of endometrial receptivity which includes collecting and comparing lipid biomarker patterns to reference lipidomic biomarkers, particularly prostaglandins PGE2 and/or PGF2?. The method is especially applicable for determining status fertility of a mammalian female, preferably, a woman.

Abstract: A gas turbine is provided and includes a compressor, which via an air intake inducts and compresses air; a combustion chamber, in which a fuel is combusted using the compressed air, producing a hot gas; and a turbine, equipped with turbine blades, in which the hot gas is expanded, performing work. A first device is provided in order to cool turbine blades with compressed cooling air. The first device includes at least one separate compressor stage which produces compressed cooling air independently of the compressor.

Abstract: Disclosed herein is a method for preventing ovarian hyperstimulation syndrome in a subject by administering an effective amount of a dopamine agonist in a pharmaceutically acceptable carrier. Also disclosed herein is a method for treating ovarian hyperstimulation syndrome by administering an effective amount of a dopamine agonist in a pharmaceutically acceptable carrier.

Abstract: The present invention relates to isolated polypeptides and isolated nucleic acid sequences encoding the polypeptides, as well as methods for producing and using the polypeptides in animal feed. An example of a polypeptide of the invention is the so-called L12 protein from Bacillus licheniformis ATCC 14580 which improves the Feed Conversion Ratio (FCR) and/or acts as a gut microflora modulator. The invention furthermore relates to the probiotic use of strains of Bacillus which produce proteins related to L12.

Abstract: An arrangement between blade elements in a blade row in a turbine is described. Each blade element has at least one shroud element and a blade airfoil which abuts on, and is connected to, the shroud element, and essentially extends radially with regard to a principal axis of the blade row. When installed, the shroud element sides, which extend circumferentially, abut on the respectively adjacent shroud element of the respectively adjacent blade element, each forming an essentially radial gap. At least one blade element has a projection which projects into the shroud element of the abutting blade element and extends in the circumferential direction, and at least one blade element has a recess which accommodates such a projection. In the region of the projection or recess there is a stepped region of the radial gap, and the guiding of the radial gap in this stepped region is a labyrinth seal.

Abstract: A blade arrangement is provided for a gas turbine, in which blade leaves, having a leading edge and a trailing edge and also a pressure side and a suction side, are assembled sealingly with platforms configured as separate components. A peripheral sealing arrangement is provided between the blade leaves and the associated platforms, which seals off an interspace between the blade leaves and platforms against hot gas flowing around the blade leaves. A directed site-dependent supply of cooling air for purging the sealing arrangement is provided on a side of the sealing arrangement which faces away from the hot gas. A method of operating the above blade arrangement is also provided. The method includes supplying cooling air for purging the sealing arrangement at a pressure which decreases from the leading edge of the blade leaves to the trailing edge.

Abstract: A pharmaceutical composition comprising quinagolide for the treatment and/or prevention of endometriosis.

Abstract: The present invention provides methods and pharmaceutical compositions for treating tumors.

Abstract: The present invention relates to determining the receptivity of human endometrium from a gene expression profile. More specifically, the invention consists of developing a specific expression microarray of endometrial receptivity (Endometrial Receptivity Array or ERA) which allows evaluating the receptive state of a human endometrium, as well as assessing said state for diagnostic and therapeutic purposes.

Abstract: A blade is provided and includes a platform and a root configured to be connected to a blade carrier. Airfoil portions extend from opposite sides of the platform. Each airfoil portion defines an operating surface being the surface facing the other airfoil portion. An operating surface of one of the airfoil portions defines a suction side and the other operating surface of the other airfoil portion defines a pressure side.

Abstract: A gas turbine (1) includes a combustion chamber (2) followed by a stator airfoil row (4) defining a plurality of guide vanes and separated by the combustion chamber (2) by a first gap (5), and a rotor airfoil row (6) separated by the stator airfoil row (4) by a second gap (7). The stator airfoils (15) of the stator airfoil row (4) are connected to guide vane boxes (17) collecting a cooling fluid (A) and injecting it through nozzles (20) in the second gap (7) to make it to enter rotor airfoil inlets (23). The guide vane boxes (23) are provided with passages (30) connecting a zone (31) upstream of the guide vane boxes (17) to a zone (32) of the second gap (7) downstream of the guide vane boxes (32). Moreover, the mouths (3) of the passages (30) facing the rotor airfoil row (6) are closer to a hot gases path than the nozzles (20).

Abstract: A turbine blade is provided having an airfoil and a platform manufactured in two separate pieces, which are joined together. The blade includes a seal, which is a mechanically decoupled seal, interposed between the airfoil and platform in a position closer to a hot gases path than a joint.

Abstract: An arrangement between blade elements in a blade row in a turbine is described. Each blade element has at least one shroud element and a blade airfoil which abuts on, and is connected to, the shroud element, and essentially extends radially with regard to a principal axis of the blade row. When installed, the shroud element sides, which extend circumferentially, abut on the respectively adjacent shroud element of the respectively adjacent blade element, each forming an essentially radial gap. At least one blade element has a projection which projects into the shroud element of the abutting blade element and extends in the circumferential direction, and at least one blade element has a recess which accommodates such a projection. In the region of the projection or recess there is a stepped region of the radial gap, and the guiding of the radial gap in this stepped region is a labyrinth seal.

Abstract: The use of a dopamine agonist in the manufacture of a medicament for the treatment or prevention of endometriosis.

Abstract: Disclosed herein is a method for preventing ovarian hyperstimulation syndrome in a subject by administering an effective amount of a dopamine agonist in a pharmaceutically acceptable carrier. Also disclosed herein is a method for treating ovarian hyperstimulation syndrome by administering an effective amount of a dopamine agonist in a pharmaceutically acceptable carrier.

Abstract: The invention provides methods for generating customized hESC and lines thereof for future use in the treatment of genetic relations. In one aspect, the customized hESC lines are grown using human feeder cells or human serum from biological or genetic relations in order to reduce or preferably avoid contamination by foreign pathogens or exposure to foreign antigens.