Patents by Inventor Carmelo Gandolfi

Carmelo Gandolfi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain PGI.sub.1 compounds and pharmaceutical compositions containing them
    Patent number: 4250188
    Abstract: 2-Oxa-bicyclic prostaglandins, a method for their preparation and pharmaceutical and veterinary compositions containing them are disclosed.
    Type: Grant
    Filed: November 1, 1979
    Date of Patent: February 10, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Certain thiacyclic PGI compounds
    Patent number: 4242508
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities including, for example, hypotensive, vasodilatory, antiaggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: December 30, 1980
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Bicyclic prostaglandins
    Patent number: 4230721
    Abstract: New 2-oxa-bicyclic prostaglandin compounds, and pharmaceutical and veterinary compositions containing them, having pharmaceutical utility for example as anti-aggregating, vasodilating, and cytoprotective agents. Processes for preparing the compounds are also disclosed.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: October 28, 1980
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Fluoro-prostaglandins
    Patent number: 4229585
    Abstract: 16-fluoro-substituted prostaglandin analogs of the formula: ##STR1## in which R is hydrogen, a C.sub.1 -C.sub.12 alkyl group or a cation of a pharmaceutically acceptable base; one of R.sub.1 and R.sub.2 is hydrogen and the other is hydroxy or acyloxy or R.sub.1 and R.sub.2 take together, form a oxo group; one of R.sub.4 and R.sub.5 is hydroxy and the other is hydrogen; R.sub.6 is hydrogen, methyl or fluorine; n is zero or an integer of 1 to 6; and R.sub.7 is phenyl or phenyl substituted by at least one of halogen C.sub.1 -C.sub.6 alkoxy or trihalomethyl.
    Type: Grant
    Filed: April 27, 1979
    Date of Patent: October 21, 1980
    Assignee: Farmitalia Carlo Erba
    Inventors: Renato Pellegata, Carmelo Gandolfi
  • 13,14-Dehydro-11-deoxy-prostaglandins and process for their preparation
    Patent number: 4220759
    Abstract: 14-Halo lactone and lactol prostaglandin intermediates have been prepared.
    Type: Grant
    Filed: July 13, 1979
    Date of Patent: September 2, 1980
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Renato Pellegata, Franco Faustini, Angelo Fumagalli
  • 13,14-Dehydro-11-deoxy-prostaglandis
    Patent number: 4198430
    Abstract: Optionally active 13,14-dehydro-11-deoxy prostaglandins useful in inhibiting gastric secretions and as anti-asmthmatic agents are disclosed.
    Type: Grant
    Filed: March 8, 1976
    Date of Patent: April 15, 1980
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Renato Pellegate, Franco Faustini, Angelo Fumagalli
  • .omega.-Nor-aromatic-13,14-dehydro-prostaglandins and process for their preparation
    Patent number: 4195183
    Abstract: PGF.sub..alpha. compounds are disclosed having as the lower side chain ##STR1## in which one of R.sub.4 and R.sub.5 hydroxyl and the other is alkoxy R.sub.6 is hydrogen or alkyl, m is 0-3, E represents oxygen or sulphur and R is hydrogen, halogen, alkyl, alkoxy or trihaloalkyl.
    Type: Grant
    Filed: May 2, 1978
    Date of Patent: March 25, 1980
    Assignee: Farmitalia Certo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Franco Faustini, Walter Moretti, Mario M. Usardi, Roberto Ceserani
  • .omega.-Nor-cycloalkyl-13,14-dehydro-prostaglandins
    Patent number: 4169145
    Abstract: .omega.-NOR-CYCLOALKYL-13,14-DEHYDRO-PROSTAGLANDIN COMPOUNDS, SPECIFICALLY 13,14-DEHYDRO-17-CYCLOHEXYL-20,19,18-TRINOR-PGF.sub.2.alpha. having antiulcer and luteolytic activity, are disclosed.
    Type: Grant
    Filed: September 21, 1977
    Date of Patent: September 25, 1979
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Renato Pellegata, Roberto Ceserani, Maria M. Usardi
  • 8,12-Diisoprostanoic acid derivatives
    Patent number: 4133829
    Abstract: 8,12-Diisoprostanoic acid compounds and intermediates useful in the processes of making them have been prepared.
    Type: Grant
    Filed: February 3, 1975
    Date of Patent: January 9, 1979
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio
  • 8,12-Diisoprostanoic acid derivatives
    Patent number: 4089896
    Abstract: Optically active 8,12-diisoprostanoic acids and derivatives, processes for making same, pharmaceutical compositions containing same, and intermediates for producing same are disclosed. The acids include, for instance, 5c,13t-11.alpha.,15S-dihydroxy-9-oxo-8,12-diisoprostadienoic acid. The compounds of the present invention can be used in the same uses as the natural prostaglandins, including the treatment of asthma, parturition to facilitate child bearing labor and as abortion agents.
    Type: Grant
    Filed: December 15, 1972
    Date of Patent: May 16, 1978
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio
  • 16-Methyl prost-5-en-13-ynoic acid derivatives
    Patent number: 4041064
    Abstract: 16S and 16R methyl 13, 14 dehydro PGE.sub.2 compounds have been prepared.
    Type: Grant
    Filed: July 29, 1975
    Date of Patent: August 9, 1977
    Assignee: Carlo-Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Renato Pellegata, Maria M. Usardi
  • Omega-nor-cycloalkyl-13,14-dehydro-prostaglandins
    Patent number: 4035415
    Abstract: Omega-nor-cycloalkyl-13,14-dehydro-prostaglandin compounds, specifically 13,14-dehydro-17-cyclohexyl-20,19,18-trinor-PGF.sub.2.sub..alpha., having selective luteolytic, abortifacient and labor-inducing activity and extremely low untoward gastrointestinal effects are disclosed.
    Type: Grant
    Filed: August 8, 1975
    Date of Patent: July 12, 1977
    Assignee: Carlo Erba, S.p.A.
    Inventors: Carmelo Gandolfi, Renato Pellegata, Roberto Ceserani, Maria M. Usardi
  • Prostanoic acid intermediate
    Patent number: 4035392
    Abstract: Lactone and laclol intermediates for prosten-ynoic acids have been prepared.
    Type: Grant
    Filed: February 5, 1975
    Date of Patent: July 12, 1977
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio
  • Prostanoic acid derivatives
    Patent number: 4035414
    Abstract: 8,12-DISO-14-CHLORO PGE.sub.2 and PGF.sub.2 and 8,12-diso-prosten-ynoic acids have been prepared.
    Type: Grant
    Filed: November 13, 1975
    Date of Patent: July 12, 1977
    Assignee: Carlo Erba S.P.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio
  • 14-Chloro prostadienoic acid compounds
    Patent number: 4021477
    Abstract: 14-Chloro PG.sub.2 compounds have been prepared.
    Type: Grant
    Filed: November 13, 1975
    Date of Patent: May 3, 1977
    Assignee: Carlo-Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio
  • 5C-PROSTEN-13-YNOIC ACIDS
    Patent number: 3935254
    Abstract: 14-Chloro and 13-14 dehydro PG.sub.2 analogues have been prepared.
    Type: Grant
    Filed: March 30, 1973
    Date of Patent: January 27, 1976
    Assignee: Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Gianfederico Doria, Pietro Gaio