Abstract: Overlapping functions called in robotic process automation scripts may be used to create new efficiencies in an IT infrastructure. For example, the overlaps may be used to identify code modification impact in the IT infrastructure, may be used to remediate duplication of coding efforts across silos in an organization, and may be merged to create new efficiencies in code/script storage and/or sustaining efforts.

Abstract: Image sensor systems are disclosed that allow for charge transfer between pixels of a group included in a pixel array with a single digital readout of the accumulated charge from the group. Each of the pixels within a given group includes a photodetector. One or more pump gates are arranged between adjacent pixels of the given group to allow charge to be pumped from one pixel to the next in a serial fashion within the group. A readout circuit that includes at least a transfer gate and a capacitor may be coupled to a final pixel of the group to receive the accumulated charge and generate a photodetector signal (based on the accumulated charge) that can be amplified via a source follower component and ultimately read out to a column amplifier.

Abstract: A method for manufacturing a detector of a first and a second incident ionizing radiation including determining the abscissa em of a point of intersection between a first and a second curve, with the first and second curves representing the evolution of the number of photons or electrical charges generated per second by a transducing material as a function of the total thickness of an amplifying material when the transducing material is irradiated, through this thickness of transducing material, by the first and second incident ionizing radiation, respectively; then selecting the total thickness of amplifying material between 0.9 em and 1.1 em and producing the detector with the selected thickness of amplifying material.

Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.

Abstract: Method of treating or preventing trichomoniasis or T. vaginalis infection in a subject in need thereof, the method involving administering to the subject a therapeutically effective amount of secnidazole or a pharmaceutically acceptable salt in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules. The subject can also have bacterial vaginosis, is HIV-positive, and/or is suffering with metronidazole-resistant trichomoniasis and/or tinidazole-resistant trichomoniasis. The subject can also be a sexual partner of a person with trichomoniasis. The microgranule formulation can also be administered with paromomycin, tinidazole, metronidazole, boric acid or a combination thereof. Pharmaceutical compositions and uses for treating or preventing trichomoniasis or T. vaginalis infection in a subject in need thereof are also contemplated herein.

Abstract: Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.

Abstract: Example embodiments are directed to systems and methods for providing end of route navigation. A network system identifies a destination of a route and retrieves a display template based on the destination. The display template provides guidelines for display of end of route content, whereby the display of the end of the route content is different than display of content during a middle of the route. Based on the display template, a display time to trigger display of the end of the route content. The display time may be associated with a threshold distance to the destination. The network system monitors a location of a vehicle along the route and accesses end of route content. Responsive to detecting that the location of the vehicle is at the threshold distance to the destination, the end of the route content is displayed on a device associated with the vehicle.

Abstract: Disclosed are various embodiments for sales lead generation utilizing a photo of a unique identifier or identifiers of a vehicle at a store. In another aspect a method for generating a sales lead from a photo of a vehicle with a unique identifier is disclosed. The method first provisions a relational database with a dataset of unique vehicle identifiers. Next, is provisioning the field device with a sales/lead application. Then executing the sales/lead application on non-transitory memory of the field device. Then capturing a photo of a vehicle with a unique identifier. Next, transmitting photo to a central system. Then processing the photo for optical character recognition with an image analysis module. The method then generates the unique vehicle identifier from the photo. Next, it accesses the relational database to perform a lookup of the unique vehicle identifier. Lastly, it generates a sales lead based on at least the unique vehicle identifier.

Abstract: A method for forming glass ceramic articles includes heating a stack of glass sheets to a nucleation temperature to create a nucleated crystallizable stack of sheets; heating the nucleated crystallizable stack of glass sheets to a crystallization temperature; and maintaining the crystallization temperature for a predetermined period of time to produce the glass-ceramic articles. The stack of glass sheets has a mass index of less than or equal to 35.

Abstract: Isolated anti-human CD45RC antibodies or binding fragments thereof, nucleic acids and expression vector encoding the same, compositions including the same, and uses thereof as medicaments, including for the prevention and/or treatment of CD45RChigh-related diseases (including autoimmune diseases, undesired immune responses, monogenic diseases, and lymphoma or cancer), in particular for use in preventing and/or treating graft-versus-host disease (GVHD).

Abstract: A method of collecting oral mucosal cells from a patient and evaluating the oral mucosal cells for oral squamous cell carcinoma predisposition in the patient includes collecting a sample of chewing gum from a patient that had chewed the chewing gum for a minimum of about 5 minutes up to about 30 minutes. The chewing gum includes a molecular adherent targeted towards oral mucosal cells with oral squamous cell carcinoma predisposition. A polymerase chain reaction (PCR) is performed on a DNA template prepared from the chewed chewing gum using oligonucleotide primers that are selected to amplify nucleic acids that screen for genomic sequence variations seen in genes that are indicative of oral squamous cell carcinoma predisposition in the patient.

Abstract: Systems, methods, and apparatuses are provided for self-contained nucleic acid preparation, amplification, and analysis.

Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.

Abstract: The current invention involves the use of protein lectins produced by plants including the non-toxic carbohydrate binding subunits (B subunits) of plant “AB toxins” (PTB lectins) as delivery vehicles for mobilizing associated drug substances for delivery to animal and human cells. The resulting protein fusions or conjugates retain lectin carbohydrate specificity for binding to cells and cellular trafficking activity so as to deliver an associated drug compound to the site of disease manifestation. One embodiment of this invention concerns the ability of ricin toxin B subunit, as a model PTB lectin, to deliver enzyme replacement therapeutic drugs to cells of several organs of the body including the brain and central nervous system, eyes, ears, lungs, bone, heart, kidney, liver, and spleen for treating lysosomal diseases.

Abstract: Plant cell fate and development is altered by treating cells with cellular reprogramming factors. Embryogenesis inducing morphogenic developmental genes are used as cellular reprogramming factors, specifically comprising polypeptides or polynucleotides encoding gene products for generating doubled haploids or haploid plants from gametes. Maize microspores treated by contacting the isolated cells with an exogenous purified, recombinant embryogenesis inducing morphogenic developmental gene polypeptide results in embryogenesis. The gametes of a maize plant develop into embryoids when transformed with a genetic construct including regulatory elements and structural genes capable of acting in a cascading fashion to alter cellular fate of plant cells. Developmental morphogenic proteins expressed from a genetic construct are used for ex situ treatment methods and for in planta cellular reprogramming.

Abstract: The punching flank 303 on the shaping press 30 makes a second angle ? with the grain of the wood fibers. In order to allow a wider variety of shapes to be pressed into the workpiece and facilitate the demolding of the object from the press after pressing, this angle may vary between 0° and 5°. Thus, the profile of the shaping press on its punching flank may be slightly tapered as illustrated in FIG. 6. This second angle ? additionally makes it possible to obtain a higher quality finish on the internal surface of the wood object.

Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.

Abstract: A glass-ceramic includes greater than or equal to 55 wt % to less than or equal to 75 wt % SiO2; greater than or equal to 2 wt % to less than or equal to 10 wt % Al2O3; greater than or equal to 8 wt % to less than or equal to 15 wt % Li2O; greater than or equal to 2 wt % to less than or equal to 4 wt % P2O5; greater than or equal to 0.05 wt % and less than or equal to 4.0 wt % CaO; greater than or equal to 5 wt % to less than or equal to 15 wt % ZrO2; and a phase assemblage comprising a crystalline phase and a glass phase, wherein: a ratio of Li2O to Al2O3 is greater than 2 and less than or equal to 4; and a ratio of Li2O to ZrO2 is greater than or equal to 1.2 and less than or equal to 1.7.

Abstract: According to one or more embodiments, a polyethylene composition, which may include a first polyethylene fraction area defined by an area in an elution profile via iCCD analysis method in a temperature range of 45° C. to 90° C.; a first peak in the temperature range of 45° C. to 90° C. in the elution profile; a second polyethylene fraction area defined by an area in the elution profile in a temperature range of 90° C. to 120° C.; a second peak in the temperature range of 90° C. to 120° C. in the elution profile; and a local minimum in a temperature range of from 80 C to 95° C. in the elution profile. The polyethylene composition may have a density of 0.924 g/cm3 to 0.936 g/cm3 and a melt index (I2) of 0.5 g/10 minutes to 1.2 g/10 minutes. A ratio of the first polyethylene fraction area to the second polyethylene fraction area may be 2.0 to 4.0.