Patents by Inventor Caryn Bowe

Caryn Bowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Remodeling and glycoconjugation of peptides
    Publication number: 20060287223
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
    Type: Application
    Filed: April 12, 2006
    Publication date: December 21, 2006
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Caryn Bowe
  • Activated forms of water-soluble polymers
    Publication number: 20060276618
    Abstract: The present invention provides compositions of activated water-soluble polymers for preparing water-soluble polymer-modified peptides. Exemplary compounds of the invention include water-soluble polymers covalently attached to activated leaving groups wherein the water-soluble polymer is a member selected from PEG, PPG, PEG derivatives, and PPG derivatives, and the activated leaving group is a member selected from (formula I).
    Type: Application
    Filed: March 18, 2004
    Publication date: December 7, 2006
    Inventors: Shawn DeFrees, David Zopf, Caryn Bowe
  • Remodeling and glycoconjugation of peptides
    Patent number: 7138371
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: November 21, 2006
    Assignee: Neose Technologies, Inc
    Inventors: Shawn DeFrees, David A. Zopf, Caryn Bowe
  • Glycoconjugates including more than one peptide
    Patent number: 7125843
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: October 24, 2006
    Assignee: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Erythropoietin: remodeling and glycoconjugation of erythropoietin
    Publication number: 20060088906
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: July 15, 2005
    Publication date: April 27, 2006
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Glycopegylated factor IX
    Publication number: 20060040856
    Abstract: The present invention provides conjugates between Factor IX and PEG moieties. The conjugates are linked via an intact glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
    Type: Application
    Filed: June 23, 2005
    Publication date: February 23, 2006
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, Robert Bayer, Caryn Bowe, Krishnasamy Panneerselvam
  • Remodeling and glycoconjugation of peptides
    Publication number: 20060030521
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 9, 2006
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Remodeling and glycoconjugation of peptides
    Publication number: 20050106658
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
    Type: Application
    Filed: October 9, 2002
    Publication date: May 19, 2005
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Factor IX: remodeling and glycoconjugation of factor IX
    Publication number: 20050100982
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: May 12, 2005
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Interleukin-2:remodeling and glycoconjugation of interleukin-2
    Publication number: 20050031584
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: February 10, 2005
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Glycoconjugation methods and proteins/peptides produced by the methods
    Publication number: 20040142856
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: July 22, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Remodeling and glycoconjugation of peptides
    Publication number: 20040137557
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
    Type: Application
    Filed: November 5, 2002
    Publication date: July 15, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Glycopegylation methods and proteins/peptides produced by the methods
    Publication number: 20040132640
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: July 8, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Follicle stimulating hormone: remodeling and glycoconjugation of FSH
    Publication number: 20040126838
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: July 1, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Interferon beta: remodeling and glycoconjugation of interferon beta
    Publication number: 20040115168
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: June 17, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Interferon alpha: remodeling and glycoconjugation of interferon alpha
    Publication number: 20040082026
    Abstract: The invention includes a multitude of methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: April 29, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
    Publication number: 20040077836
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: April 22, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen
  • Alpha galalctosidase a: remodeling and glycoconjugation of alpha galactosidase A
    Publication number: 20040043446
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 9, 2003
    Publication date: March 4, 2004
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David Zopf, Robert Bayer, Caryn Bowe, David Hakes, Xi Chen