Abstract: Systems and methods for units of work based on business objectives are disclosed. Exemplary implementations may: manage environment state information maintaining a collaboration environment configured to facilitate interaction by users, the environment state information defining units of work and business objectives associated with the units of work; obtain progress information, the progress information for individual business objectives conveying progress toward fulfillment of the individual business objectives; update objective records for the business objectives based on the progress information so that the progress of the business objectives is maintained by the objective records; and/or perform other operations.

Abstract: Provided are SpdE polypeptides and variants and nucleic acids encoding the SpdE polypeptides and variants. Also provided are vectors including one or more nucleic acids encoding a SpdE polypeptide or variant and cells including a nucleic acid encoding the SpdE polypeptide or variant, as well as cells expressing a SpdE polypeptide or variant and compositions including such cells and a pharmaceutically acceptable carrier. Finally, methods of detecting presence and/or amount of one or more amino acids in a sample are provided. The methods include contacting the sample with a SpdE protein, measuring diguanylate cyclase activity of the SpdE protein; and comparing the diguanylate cyclase activity of the SpdE protein to a control. The methods can utilize isolated SpdE protein or a cell expressing a SpdE protein.

Abstract: The invention provides compounds for use in inhibiting a microbial alternative oxidase (AOX) and/or cytochrome bc1 complex. The invention extends to the use of such inhibitors in agrochemicals and in pharmaceuticals, for treating microbial infections, including fungal infections.

Abstract: Quaternary ammonium compounds and methods of using such compounds to, for example, break oil-in-water emulsion treatment fluids are provided. In some embodiments, such methods include introducing a quaternary ammonium compound into an oil-in-water emulsion treatment fluid that comprises an oleaginous phase and an aqueous phase; and centrifuging at least the portion of the oil-in-water emulsion treatment fluid to separate at least a portion of the oil-in-water emulsion treatment fluid into an oleaginous fluid and an aqueous fluid.

Abstract: Methods, systems, and computer-readable storage media for providing reading performance feedback to a user from a voice recording of the user reading an arbitrary text. A target text comprising a text passage that a user intends to read and a user recording comprising an audio recording of the user reading the target text aloud are received from a user device. The user recording is converted to a user speech hypothesis comprising text corresponding to speech recognized in the audio recording. The user speech hypothesis is then compared to the target text to generate reading performance feedback comprising relevant differences between the speech in the user recording and the target text and the reading performance feedback is displayed to the user on the user device.

Abstract: An all-purpose drainage catheter which includes an all-purpose drainage catheter lumen, an extension tubing, a collection bag, a catheter hub, a Luer valve. The extension tubing inserted into the all-purpose drainage catheter lumen. The collection bag is fluidly coupled to the extension tubing. The Luer valve facilitates nephrostomy care so that when the all-purpose drainage catheter is in place urine flows from the renal pelvis into the all-purpose drainage catheter lumen, the extension tubing and the collection bag. The Luer valve employs a scalloped Luer-style male connector which, when screwed into the catheter hub, further allows urine to flow from the renal pelvis into the all-purpose drainage catheter lumen, the extension tubing and the collection bag. The all-purpose drainage catheter includes an outer catheter hub, an inner catheter hub coupled to the Luer valve at one end thereof and insertedly coupled to the outer catheter hub.

Abstract: In an example, a bed exercise system is described. The bed exercise system includes a foot pad, a first elastic connector having a first end coupled to a first lateral side of the foot pad and a second end, and a second elastic connector having a first end coupled to a second lateral side of the foot pad and a second end. The bed exercise system also includes an anchor coupled to the second end of the first elastic connector and the second end of the second elastic connector. The anchor is configured to fasten, at a fixed position relative to a bed, the second end of the first elastic connector and the second end of the second elastic connector while (i) the foot pad is moved between a first position and a second position relative to a bed, and (ii) a tension on the first elastic connector and a tension on the second elastic connector increases as the foot pad moves from the first position to the second position.

Abstract: Embodiments provide for identifying and resolving conflicts in access permissions migrated data by receiving a set of mappings including path mappings of a hierarchy of data objects on the source system to locations on the target system for migrated data objects. Based on the received set of mappings, permissions controlling access to data objects of the hierarchy of data objects on the source system can be translated to permissions controlling access to the migrated data objects on the target system for one or more user accounts on the target system. One or more conflicts can be detected between permissions on the source system and permissions on the target system. A conflict resolution strategy can be selected from a plurality of conflict resolution strategies and the selected conflict resolution strategy can be applied to the permissions controlling access to the migrated data objects on the target system.

Abstract: The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

Abstract: This disclosure provides crystalline forms of trofinetide and trofinetide hydrate, pharmaceutical compositions comprising crystalline forms of trofinetide and trofinetide hydrate, methods of making crystalline forms of trofinetide or trofinetide hydrate, and methods of treating a disease, condition, or disorder in a subject comprising administering a composition comprising crystalline forms of trofinetide or trofinetide hydrate to the subject.

Abstract: The present application relates to a lubricant composition comprising, in relation to the total weight of the lubricant composition at least one base oil; 0.005 to 10% by weight of at least one polymeric organic friction modifier; and 0.005 to 10% by weight of at least one ester said polymeric organic friction modifier is a compound of formula (I): R1.[(AO)n.-AO—R2]m ??(I) wherein R1 is a residue of a group having at least m hydrogen atoms, m being greater than 2; AO is an alkylene oxide residue; n is between 0 and 100; R2 is a hydrogen atom or a C—(O)—R3 group with R3 being a residue.

Abstract: A protective dressing includes an outer dressing and an adhesive layer. The outer dressing includes an opening and a cavity sized to receive a phase-change material (PCM) insert inserted through the opening. The adhesive layer is configured to adhere to a patient's skin surrounding an anatomic site. When adhered to the patient's skin, the PCM insert modifies the patient's skin at the anatomic site. The PCM insert may be removed and replaced with another PCM insert. For example, a warm PCM insert may be replaced with a refrigerated PCM insert. The opening of the outer dressing may be self-sealing. The opening of the outer dressing may be sealed with an upper layer dressing coupled to the PCM cooling insert.

Abstract: Non-naturally occurring microorganisms are provided that produce C40 carotenoid compound(s), utilizing exogenously added enzyme activities. Methods of producing C40 carotenoid compounds in microbial cultures, and feed and nutritional supplement compositions that include the C40 carotenoid compounds produced in the microbial cultures, are also provided.

Abstract: Encoding of domain logic rules in an analog content addressable memory (aCAM) is disclosed. By encoding domain logic in an aCAM, rapid and flexible search capabilities are enabled, including the capability to search ranges of analog values, fuzzy match capabilities, and optimized parameter search capabilities. This is achieved with low latency by using only a small number of clock cycles at low power. A domain logic ruleset may be represented using various data structures such as decision trees, directed graphs, or the like. These representations can be converted to a table of values, where each table column can be directly mapped to a corresponding row of the aCAM.

Abstract: Method for manufacturing microcapsules enclosing a substance referred to as the active substance, in which method: there are provided an aqueous solution of a surfactant, an oily phase comprising the active substance and at least a first monomer X, and a polar phase having at least a second monomer Y; an O/W emulsion is prepared by adding the oily phase to the aqueous solution of the surfactant; the polar phase is added to the O/W emulsion in order to obtain a polymer by polymerisation of the X and Y monomers; starting from this reaction mixture, the microcapsules are isolated and comprise a wall which is formed by the polymer and which encloses the active substance; the polymer is a poly(beta-amino ester).

Abstract: Pesticidal protein exhibiting toxic activity against Lepidopteran and Hemipteran pest species are disclosed, and include, but are not limited to, TIC2199. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the disclosed pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Lepidopteran and Hemipteran species pests using TIC2199 pesticidal protein are also provided.

Abstract: A computerized method produces an identity code to identify each subject stored in the computer systems connected to a computer network while protecting the privacy and confidentiality of the subject. A central computer system receives an identity code of a suspect of a financial crime and sends the identity code to all computer systems connected to the computer network. The computer systems that have the matched identity code send the requested information to the central computer system. As a result, law enforcement organizations can eliminate crimes and financial institutions can recover the money stolen from them. In addition, law enforcement organizations and financial institutions can identify money launderers that are missed by their anti-money laundering transactional monitoring systems.

Abstract: A lubricant composition comprising, in relation to the total weight of the lubricant composition: at least one base oil; 0.005 to 10% by weight of at least one polymeric organic friction modifier; and 0.005 to 10% by weight of at least one ester, said polymeric organic friction modifier being the reaction product of: a) at least one hydrophobic polymer subunit which comprises a hydrophobic polymer selected from polyolefins, polyacrylics and polystyrenes; b) at least one hydrophilic polymer subunit which comprises a hydrophilic polymer selected from polyethers, polyesters and polyamides; c) optionally at least one backbone moiety capable of linking polymeric subunits together; and d) optionally a chain termination group.

Abstract: Apparatuses and methods for reducing or limiting bleeding in an animal by focused ultrasound (FUS) stimulation of the spleen. The apparatuses and methods may be used treat blood disorders such as hemophilia, or to reduce hemorrhage in surgery or due to traumatic injury. The methods may be non-invasively administered to the patient by transcutaneous application of ultrasound energy.

Abstract: Systems that may be used for performing a robotic revision knee arthroplasty are disclosed. Such systems can optionally include a processor that can: intraoperatively receive a plurality of position data obtained by a robotic surgical device after a primary implant has been removed from a bone, the plurality of position data correspond to a plurality of landmarks of the bone of a patient, the plurality of landmarks include a position of an intramedullary canal of the bone; select from a database having a plurality of mean models of a corresponding bone a mean model that comprises a best match based upon the plurality of landmarks of the bone; generate an updated model by altering the mean model to fit an anatomy of the bone of the patient based upon the plurality of landmarks; and output to a user interface the updated model for use during the robotic revision knee arthroplasty.