Abstract: Disclosed herein are methods for introducing functional mitochondria into liver cells in living animals (e.g., mammals). The disclosed compositions and methods can be used to treat clinical conditions characterized by genetic or acquired mitochondrial defects and the resulting dysfunctions and diseases therefrom.

Abstract: Systems, devices, methods, and computer readable medium for evaluating visual quality of digital content are disclosed. Methods can include identifying content assets including one or more images that are combined to create different digital components distributed to one or more client devices. A quality of each of the one or more images is evaluated using one or more machine learning models trained to evaluate one or more visual aspects that are deemed indicative of visual quality. An aggregate quality for the content assets is determined based, at least in part, on an output of the one or more machine learning models indicating the visual quality of each of the one or more images. A graphical user interface of a first computing device is updated to present a visual indication of the aggregate quality of the content assets.

Abstract: Methods for creating semolina flour-based shape-changing food from a multi-layered dough with at least one grooved surface. The dough layers have difference compositions including natural, staple and edible ingredients. The dough is exposed to stimuli during dehydration (e.g., baking) or hydration (e.g., boiling) processes.

Abstract: A device for collecting urine discharged from a body of a user includes a fluid collection assembly having at least one layer for drawing urine discharged from the body into an interior cavity, an external covering that covers a portion of the at least one layer, and at least one fenestration for receiving urine, wherein the fenestration is a portion of the fluid collection assembly that is uncovered by the external covering. The device further includes a cap enclosing a first end of the assembly, a tube having a first end in fluid communication with the cap, and a shape retaining element configured to conform the assembly to a curved configuration and maintain the curved configuration until the configuration is adjusted. The assembly is configured to be disposed against the body of the user, with the at least one fenestration in operative relation with a urethral opening of the user.

Abstract: A method of manufacturing an electronic circuit (or circuit module) (100) is disclosed. The electronic circuit comprises a transistor (1) and a resistor (2), the transistor comprising a source terminal (11), a drain terminal (12), a gate terminal (13), and a first body (10) of material providing a controllable semi-conductive channel between the source and drain terminals, and the resistor comprises a first resistor terminal (21), a second resistor terminal (22), and a second body (20) of material providing a resistive current path between the first resistor terminal and the second resistor terminal. The method comprises: forming the first body (10); and forming the second body (20), wherein the first body comprises a first quantity (100) of a metal oxide and the second body comprises a second quantity (200) of said metal oxide. Corresponding electronic circuits are disclosed.

Abstract: A stand-alone modular removable rudder system for watercraft having a rudder comprising a steering handle coupled to a quick release mechanism adapted to releasably secure said steering handle to said watercraft in proximity to the operator, said system further comprising, a rudder mount adapted to be coupled to the rear of the watercraft by a quick release mechanism adapted to releasably secure said rudder mount to said watercraft, said rudder being carried by a rudder support pivotal about said rudder mount and cables operatively connecting said steering handle to said rudder mount whereby the steering handle can be operated to steer the rudder.

Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other applications, for treatment of liver deficiencies, liver metabolism studies, and liver toxicity studies, fibrogenic studies, or to support hepatocyte function in co-culture setting.

Abstract: The invention concerns a disposable individual overall (1) for protection against radioactive particles, comprising a zip closure (FG1) from top to bottom and on the front in the trunk portion (3). The invention is characterized in that at least one other closure (FG2) extends from top to bottom in at least one of the legs (31, 32) of the trouser part (3) and comprises two strips (BA31, BA32) capable of being connected along another prescribed meshing line (LE3), at least one junction point (S) connecting two of the strips (BA31, BA32) beyond the other line (LE3) being present between the closure (FG1) and the other closure (FG3) in the closed state, a breaking member (CU) being provided on at least one of the closures (FG1, FG3) in order to allow breaking of the junction point (S) by pulling on the breaking member (CU).

Abstract: A method for predicting a three-dimensional representation in a three-dimensional scene, using one or more two-dimensional representations, obtained from at least one image generated by a camera. The method includes obtaining a forest of regression trees, and for the at least one image: extracting a 2D representation associated with one or more positions within the image; predicting a 3D representation, corresponding to the extracted 2D representation, using the regression tree forest includes a set of possible associations between at least one 2D representation and a 3D representation, each possible association resulting from a predictive model; evaluating one or more of the possible associations of the regression tree forest, according to a predetermined confidence criterion; and updating the regression tree forest including a deactivation of one or more possible associations, depending on the evaluation of the possible associations.

Abstract: A method of treating a patient suffering from low back by administering to the patient a pharmaceutical composition comprising a therapeutically effective amount of an antibody that binds specifically to nerve growth factor (NGF) or an antigen binding fragment thereof.

Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.

Abstract: Multicompartment water-soluble unit dose articles and methods of making them.

Abstract: A support assembly (100) for supporting a transverse incision site (420) of a user (101) includes an assembly body (106) and a first assembly arm (102). The assembly body (106) is configured to encircle an abdomen (107) and at least one leg (311) of the user (101). The assembly body (106) includes a pelvic support layer (214) that is configured to provide a transverse supportive force to the transverse incision site (420) of the user (101). The first assembly arm (102) is coupled to the pelvic support layer (214). The first assembly arm (102) extends anteriorly from the assembly body (106). The first assembly arm (102) is configured to extend from a groin region (109) of the user (101) and secure to the assembly body (106) to adjust the transverse supportive force to the transverse incision site (420) at the peri-pelvic area (421).

Abstract: The application relates to amide derivatives of formula (I), processes for their preparation, pharmaceutical compositions, and their uses, more particularly their uses in treating chronic hepatitis B virus (HBV) infection:

Abstract: This disclosure describes systems and methods that facilitate purchase of objects from merchants. For example, a user may browse a website available from an object management service and identify objects that they desire to purchase. Rather than having to locate the seller of those objects to make a purchase, the implementations described herein facilitate a connection between the user and the merchant so that the merchant's sales are increased and the user is provided an efficient and safe shopping experience.

Abstract: To control vehicular congestion at intersections, a method includes detecting a group of two or more vehicles stopped at an intersection regulated by a traffic light, where for each of the vehicles in the group, movement through the intersection in response to a change in a state of the traffic light is affected by movement of at least one other vehicle in the group. The method further includes determining a time when the state of the traffic light changes to allow the group of vehicles to start moving through the intersection, determining acceleration parameters for a certain vehicle in the group in view of potential and/or actual movement of the other vehicles in the group through the intersection, and providing guidance to a device operated by a driver of the certain vehicle regarding the determined acceleration parameters, in accordance with the determined time.

Abstract: Generally discussed herein are devices, systems, and methods for improving phishing webpage content detection. A method can include identifying first webpage content comprises phishing content, determining, using a reinforcement learning (RL) agent, at least one action, generating, based on the determined at least one action and the identified first webpage content, altered first webpage content, identifying that the altered first webpage content is benign, generating, based on the determined at least one action and second webpage content, altered second webpage content, and training, based on the altered second webpage content and a corresponding label of phishing, a phishing detector.

Abstract: An analog content addressable memory (aCAM) that enables parallel searching of analog ranges of values and generates analog outputs that quantify matches between input data and stored data is disclosed. The input data can be compared with the stored data, and the input data can be determined to match the stored data based on a value associated with the input data being within a range associated with the stored data. The aCAM can generate an analog output that represents a number of matches and a number of mismatches between the input data and the stored data. Based on the analog output, whether the input data matches the stored data and a degree to which the input data matches the stored data can be determined.