Abstract: A network device detecting possible malicious traffic and enlists the help of a co-operative group of downstream routers to perform enhanced deep packet analysis and firewalling in parallel with the transport of the packet through the network. The routers may also use other remote computational resource to perform some of the analysis along or close to the route 80 of the packet through the network. The packets are cached at the exit edge router, which does not release the packet from the cooperative group until all analyzers report the traffic is safe, or deletes the traffic if identified as malicious. By buffering at the remote end the packet can be forwarded promptly if approved, but protects downstream components if the traffic is malicious.

Abstract: An authentication method using a plurality of physical unclonable functions (PUFs). The plurality of PUFs includes a first PUF associated with a first device and a second PUF associated with a second device. A surface pattern of the first PUF corresponds to a surface pattern of the second PUF. The method includes obtaining a first response to a challenge using the first PUF, sending a request to the second device for a second response to the challenge obtained used the second PUF, receiving the second response, and determining whether the second device is authenticated based on a comparison between the first response and the second response.

Abstract: An optical network comprising: an optical splitter configured to split an optical signal incident on the optical splitter into at least a control signal and a data signal; an optical switch; a first optical path configured to carry the control signal between the optical splitter and the optical switch; and a second optical path configured to carry the data signal between the optical splitter and the optical switch. The optical network is configured to transmit the control and data signals such that the data signal is incident on the optical switch after the control signal. The optical switch is configured to selectively switch the optical network between a first configuration and a second configuration in accordance with the control signal. The application also relates to a method of configuring an optical network.

Abstract: There is herein provided a method of quantum communication, the method comprising: indicating to a quantum receiving apparatus that a first sequence of mutually non-orthogonal bases will be used to prepare at least some of a plurality of bits in quantum states, at a quantum transmitting apparatus, preparing each of the plurality of bits in a respective one of a second sequence of mutually non-orthogonal bases, to give a plurality of qubits, wherein the second sequence of mutually non-orthogonal bases is different to the first sequence of mutually non-orthogonal bases.

Abstract: An agricultural admixture includes an acid, an organic amine, boron and one or more additional micronutrients, in which the boron and additional micronutrients are chelated, along with a saccharide. In the admixture, boron is present in an amount of at least 1.0 wt % thereof, the admixture contains a total boron and additional micronutrients content of at least 7.2 wt %, and the admixture remains stable, non-precipitated for at least 60 days. A method of spraying an agricultural admixture involves admixing the aforementioned admixture with one or more agricultural chemicals and spraying the admixture, where the admixture remains stable, non-precipitated for at least 60 days. A method of producing an agricultural admixture involves admixing the aforementioned admixture with one or more agricultural chemicals, where the admixture remains stable, non-precipitated for at least 60 days.

Abstract: A network device detecting possible malicious traffic and enlists the help of a co-operative group of downstream routers to perform enhanced deep packet analysis and firewalling in parallel with the transport of the packet through the network. The routers may also use other remote computational resource to perform some of the analysis along or close to the route 80 of the packet through the network. The packets are cached at the exit edge router, which does not release the packet from the cooperative group until all analyzers report the traffic is safe, or deletes the traffic if identified as malicious. By buffering at the remote end the packet can be forwarded promptly if approved, but protects downstream components if the traffic is malicious.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: Disclosed is apparatus and a method for detecting udder disease in dairy animals. An accelerometer is attached to each of a plurality of dairy animals. A processor determines a measure of the activity of the dairy animals to which the accelerometers are attached. Data is recorded by and automatically transmitted from a sensor unit secured to an animal, without the requirement for costly and time consuming chemical analysis of milk, or of visual or veterinary inspection of individual animals in a herd. The development of an udder disease in a dairy animal, such as mastitis, may be identified from a decrease in the monitored measure of activity of a dairy animal. A separate baseline measure of activity may be determined for each dairy animal and the activity of a plurality of dairy animals in one or more herds may be taken into account, in order to reduce false positives due to external effects which are not specific to a single dairy animal.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes: (I). The present invention is also directed to uses of the tricyclic compounds described herein in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: An apparatus according to the present invention comprises a chamber into which carbon nanotubes dispersed in a non-polar solvent may be received. The nanotubes are impelled along the chamber by the application of an external electrical field and will pass through a charging element that imposes an electrical charge on the nanotubes, and a template (180), such that the nanotubes are deposited on a substrate located next to the template. The substrate may be moved relative to the template such that the nanotubes are deposited on the substrate in a predetermined selective manner.

Abstract: Disclosed is apparatus and a method for detecting udder disease in dairy animals. An accelerometer is attached to each of a plurality of dairy animals. A processor determines a measure of the activity of the dairy animals to which the accelerometers are attached. Data is recorded by and automatically transmitted from a sensor unit secured to an animal, without the requirement for costly and time consuming chemical analysis of milk, or of visual or veterinary inspection of individual animals in a herd. The development of an udder disease in a dairy animal, such as mastitis, may be identified from a decrease in the monitored measure of activity of a dairy animal. A separate baseline measure of activity may be determined for each dairy animal and the activity of a plurality of dairy animals in one or more herds may be taken into account, in order to reduce false positives due to external effects which are not specific to a single dairy animal.

Abstract: The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes: (I). The present invention is also directed to uses of the tricyclic compounds described herein in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.

Abstract: The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, Ra1, Ra2, Rb1, Rb2, Rc, Rd, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.

Abstract: Disclosed is apparatus and a method for detecting udder disease in dairy animals. An accelerometer is attached to each of a plurality of dairy animals. A processor determines a measure of the activity of the dairy animals to which the accelerometers are attached. Data is recorded by and automatically transmitted from a sensor unit secured to an animal, without the requirement for costly and time consuming chemical analysis of milk, or of visual or veterinary inspection of individual animals in a herd. The development of an udder disease in a dairy animal, such as mastitis, may be identified from a decrease in the monitored measure of activity of a dairy animal. A separate baseline measure of activity may be determined for each dairy animal and the activity of a plurality of dairy animals in one or more herds may be taken into account, in order to reduce false positives due to external effects which are not specific to a single dairy animal.

Abstract: The present application provides stabilized formulations of furin (e.g., rfurin) containing a sugar, sugar alcohol, and/or non-ionic surfactant. As compared to non-stabilized compositions, the furin formulations disclosed herein retain greater amounts of furin activity and monomeric furin content, while reducing furin aggregation when stored and/or subjected to mechanical stress. Also provided are methods for stably diluting furin (e.g., rfurin) compositions.