Abstract: Embodiments of the present disclosure provide a display panel, a manufacturing method therefor, and a display apparatus. The display panel includes a first substrate and a second substrate which are aligned, liquid crystals are filled between the first substrate and the second substrate, the first substrate and the second substrate which are aligned have a display region and a peripheral region surrounding the display region, the peripheral region is provided with a frame sealing adhesive located between the first substrate and the second substrate and surrounding the display region, and the frame sealing adhesive is configured to seal the liquid crystals.

Abstract: Antibody-drug conjugate compounds comprising a linker and methods of using such compounds are provided.

Abstract: Provided is a display panel. The display panel includes: a first substrate and a second substrate disposed opposite to each other, and a liquid crystal layer disposed between the first substrate and the second substrate; wherein the first substrate comprises a first base substrate, a plurality of first signal lines and a plurality of second signal lines disposed on a side, close to the second substrate, of the first substrate; and the second substrate comprises a second base substrate, and a shielding layer disposed on a side, close to the first substrate, of the second base substrate.

Abstract: A method for determining a centerline of a blood vessel in an image associated with a subject is provided. The method includes obtaining a centerline model used for identifying a centerline of a blood vessel and identifying the centerline of the blood vessel based on the centerline model.

Abstract: A method for improving wheat resistance to Fusarium head blight (FHB) by genome editing is provided, and further provided is use of TaCIPK14 protein or related biomaterial thereto in the regulation of plant resistance to FHB; the TaCIPK14 protein is TaCIPK14-4A protein (SEQ ID NO: 4), TaCIPK14-4B protein (SEQ ID NO: 5), and/or TaCIPK14-4D protein (SEQ ID NO: 6). TaCIPK14 knockout mutant plants are successfully obtained by simultaneously editing three alleles of TaCIPK14 in wheat using CRISPR-Cas9 gene editing technology. The TaCIPK14 knockout mutant shows resistance to inoculation with FHB pathogens, and the results of evaluation of major agronomic traits confirm that the TaCIPK14 knockout mutant reserves the major agronomic traits.

Abstract: Provided herein are compounds having the following structure: wherein the substituents are as defined herein, compositions comprising an effective amount of a compound, and methods for modulating activity of KRAS G12D and/or G12V.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes: a substrate, a common electrode line, a gate line, a first insulating layer, a data line, a second insulating layer, a pixel electrode layer, a first orientation layer, a liquid crystal layer, a second orientation layer, and a common electrode layer; wherein an angle between an extending direction of the common electrode line and a rubbing direction of the first orientation layer ranges from 0 degrees to 30 degrees or from 60 degrees to 90 degrees, and an angle between an extending direction of the gate line and the rubbing direction of the first orientation layer ranges from 0 degrees to 30 degrees or from 60 degrees to 90 degrees.

Abstract: Embodiments of the present disclosure provide a display panel, a manufacturing method therefor, and a display apparatus. The display panel includes a first substrate and a second substrate which are aligned, liquid crystals are filled between the first substrate and the second substrate, the first substrate and the second substrate which are aligned have a display region and a peripheral region surrounding the display region, the peripheral region is provided with a frame sealing adhesive located between the first substrate and the second substrate and surrounding the display region, and the frame sealing adhesive is configured to seal the liquid crystals.

Abstract: Provided herein are compounds having the following structure: or a pharmaceutically acceptable salt, tautomer, stereoisomer, or enantiomer thereof, wherein the substituents are as defined herein compositions comprising an effective amount of a compound, and methods for inhibiting activity of cyclin-dependent kinases.

Abstract: A display substrate and a display device relate to the technical field of displaying. The display substrate includes a plurality of display units spaced apart from each other and a plurality of connection units, the plurality of connection units being connected between two adjacent display units; the plurality of connection units include: two connection units arranged along a first direction, wherein the first direction is parallel to a stretching direction of the display substrate; wherein the two connection units arranged along the first direction are axisymmetric with respect to a first reference line, so that the plurality of connection units arranged along a second direction have a same deformation amount in a stretching state, the second direction is perpendicular to the stretching direction, and an extension direction of the first reference line is parallel to the second direction.

Abstract: A display panel and a display device are disclosed. The display panel includes: an array substrate and an opposite substrate; the display panel includes a display region and a non-display region, the display region includes a main display region and a transition display region, the transition display region has a plurality of transition pixel units, and each of the transition pixel units includes a plurality of transition sub-pixels; and a black matrix defines a plurality of transition sub-pixel opening regions in the transition display region, an orthographic projection of an edge of each transition sub-pixel opening region close to the gate line on the array substrate falls within an orthographic projection of the corresponding transition sub-pixel on the array substrate, and the edge is in a shape of a straight line.

Abstract: Provided are a supporting backplane and a display apparatus. The supporting backplane is arranged at one side of a flexible display panel, and the supporting backplane at least comprises a main bending area, wherein a bending axis corresponding to the main bending area extends in a first direction; the main bending area is provided with a plurality of first hollow holes, the plurality of first hollow holes being arranged in an array in the first direction and a second direction, which is orthogonal to the first direction; each of the first hollow holes is provided with a first middle hole area, and first arc-shaped hole areas located at two sides of the first middle hole area in the first direction.

Abstract: A display module and a display device are disclosed. The display module includes a display substrate provided with a first edge; a circuit board arranged at the first edge of the display substrate and electrically connected with the display substrate; and a supporting plate arranged on the non-display surface of the display substrate; the supporting plate is able to be bent and includes a first part and a second part, and the second part is provided with a hollow opening; the display substrate is positioned on the first part and is fixedly connected with the first part; and the circuit board is positioned on the second part and is fixedly connected with the second part.

Abstract: An embodiment of an adaptive video encoder may determine headset-related information including at least one of focus-related information and motion-related information and determine one or more video encode parameters based on the headset-related information. The adaptive video encoder may also encode a macroblock of a video image based on the one or more determined video encode parameters. Other embodiments are disclosed and claimed.

Abstract: Disclosed herein is a compound of Formula (I) having the following structure for activating T cells, promoting T cell proliferation, and/or exhibiting antitumor activity, a method of using the compounds disclosed herein for treating cancer, and a pharmaceutical composition comprising the same.

Abstract: Disclosed herein is a compound of Formula (I) for activating T cells, promoting T cell proliferation, and/or exhibiting antitumor activity, a method of using the compounds disclosed herein for treating cancer, and a pharmaceutical composition comprising the same.

Abstract: Provided are a supporting backplane and a display apparatus. The supporting backplane is arranged at one side of a flexible display panel, and the supporting backplane at least comprises a main bending area, wherein a bending axis corresponding to the main bending area extends in a first direction; the main bending area is provided with a plurality of first hollow holes, the plurality of first hollow holes being arranged in an array in the first direction and a second direction, which is orthogonal to the first direction; each of the first hollow holes is provided with a first middle hole area, and first arc-shaped hole areas located at two sides of the first middle hole area in the first direction.

Abstract: Disclosed herein is a compound of Formula (I) for activating T cells, promoting T cell proliferation, and/or exhibiting antitumor activity, a method of using the compounds disclosed herein for treating cancer, and a pharmaceutical composition comprising the same.

Abstract: The present disclosure provides a display panel and a manufacturing method thereof. The display panel includes a special-shaped display region. The display panel further includes a base substrate and a plurality of pixels on a side of the base substrate, and the plurality of pixels includes an edge pixel with an orthographic projection on the base substrate overlapped with that of an edge of the special-shaped display region on the base substrate. The edge pixel is provided with a light-shielding pattern that divides the edge pixel into a light-shielding region and a light-transmitting region. The edge pixel has a predetermined gray scale and a brightness ratio, the brightness ratio is a ratio of a brightness of the light-transmitting region to a brightness of the edge pixel when an entire region thereof is light-transmitting, and the predetermined gray scale has an exponential function relationship with the brightness ratio.

Abstract: Provided herein are compounds having the following structure: wherein the substituents are as defined herein, compositions comprising an effective amount of a compound, and methods for modulating activity of KRAS G12D and/or G12V.