Abstract: Disclosed herein are imidazotriazine and pyrrolopyrimidine derivatives or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as a G12C inhibitors, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the imidazotriazine and pyrrolopyrimidine derivatives or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as G12C inhibitors.

Abstract: The present disclosure relates to a system and method for extracting a region of interest. Image data in a first sectional plane may be acquired. The image data in the first sectional plane may include at least one first slice image and one second slice image. A first region of interest (ROI) in the first slice image may be determined. A second ROI in the second slice image may be determined. A first volume of interest (VOI) may be determined based on the first ROI, the second ROI, and characteristic information of the image data in the first sectional plane.

Abstract: Various embodiments herein provide techniques related to a content provider in a network. In embodiments, the content provider may identify a request by a client over the network for content; identify a network bandwidth; and transmit, based on the network bandwidth, (1) a base layer of the content without an enhanced layer of the content, or (2) the base layer of the content and the enhanced layer of the content. Other embodiments may be described and/or claimed.

Abstract: A fast-turn-on floating island device and a method for manufacturing thereof in the field of semiconductor technology. The device comprises a surface layer, a bottom layer and a drift layer which is located between the surface layer and the bottom layer, wherein, the drift layer comprises a plurality of epitaxial layers and a plurality of floating island layers, one of the floating island layers formed between adjacent two of the epitaxial layers, or one of the epitaxial layers between adjacent two of the floating island layers, a first doped region and a second doped region form in at least one of the floating island layers.

Abstract: An embodiment of an adaptive video encoder may include technology to determine headset-related information including at least one of focus-related information and motion-related information, and determine one or more video encode parameters based on the headset-related information. Other embodiments are disclosed and claimed.

Abstract: The present invention provides a display module and a display device. The display module comprises a display panel and heat dissipation structure; the display panel comprises a substrate, and a display substrate layer located on the substrate; the heat dissipation structure is located on the side of the substrate distant from the display substrate layer; and a gap is formed between at least part of the region of the heat dissipation structure and the substrate. The display module provided by the present invention improves the heat dissipation efficiency of the display panel.

Abstract: Methods and systems for image processing are provided. Image data may be obtained. The image data may include a plurality of voxels corresponding to a first plurality of ribs of an object. A first plurality of seed points may be identified for the first plurality of ribs. The first plurality of identified seed points may be labelled to obtain labelled seed points. A connected domain of a target rib of the first plurality of ribs may be determined based on at least one rib segmentation algorithm. A labelled target rib may be obtained by labelling, based on a hit-or-miss operation, the connected domain of the target rib, wherein the hit-or-miss operation may be performed using the labelled seed points to hit the connected domain of the target rib.

Abstract: Disclosed herein are heterocyclic compounds that may be used as STING modulators, the process for synthesis and to the use of such compounds in treatment of various diseases including cancers.

Abstract: Methods and systems for image processing are provided. Image data may be obtained. The image data may include a plurality of voxels corresponding to a first plurality of ribs of an object. A first plurality of seed points may be identified for the first plurality of ribs. The first plurality of identified seed points may be labelled to obtain labelled seed points. A connected domain of a target rib of the first plurality of ribs may be determined based on at least one rib segmentation algorithm. A labelled target rib may be obtained by labelling, based on a hit-or-miss operation, the connected domain of the target rib, wherein the hit-or-miss operation may be performed using the labelled seed points to hit the connected domain of the target rib.

Abstract: The present disclosure provides a detection method of wormlike micelles, and belongs to the technical field of analytical chemistry. In the present disclosure, z-ArN2+ is used as a chemical probe substance; a long-chain probe is added to a test solution for probing an interfacial region, and a short-chain probe is added to a surfactant-free control solution. A selectivity of the probe with different nucleophiles is determined by the above method, and a yield of an obtained product is measured by high-performance liquid chromatography (HPLC); and the wormlike micelles are detected by measuring the yield of the product using the selectivity of the short-chain probe to be converted into an interfacial mole number. The wormlike micelles are detected by chemical probes, and the chemical probes have a simple preparation method, a low cost, real-time detection, and broad prospects for use.

Abstract: The present disclosure provides a light-adjusting glass and a smart vehicle window. The light-adjusting glass has a transmittance adjustment region and an encapsulation region; the light-adjusting glass includes: a first and second substrates opposite to each other, and a dye liquid crystal layer between the first and second substrates in the transmittance adjustment region, and a frame sealant in the encapsulation region; the first substrate includes a first base and a first electrode layer on a side of the first base proximal to the dye liquid crystal layer; the second substrate includes a second base and a second electrode layer on a side of the second base proximal to the dye liquid crystal layer; a conductive structure is provided in the frame sealant; a first and second voltage transmission structures electrically insulated from each other are on the first base.

Abstract: The present invention provides a compound of Formula (I): or an enantiomer, an enantiomeric mixture, or a pharmaceutically acceptable salt thereof; wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating a disease or condition mediated by nuclear SET domain-containing protein 2 (NSD2).

Abstract: Provided is a display device, including a display screen, a transparent cover plate and a first light-shielding structure, wherein the display screen includes a display panel, a transparent bonding layer, a touch structure and a second light-shielding structure, and the display screen is provided with a through hole penetrating through the display panel, the transparent bonding layer and the touch structure. The first light-shielding structure is disposed on the transparent cover plate and surrounds the through hole, the second light-shielding structure is disposed on the touch structure and surrounds the through hole, and orthographic projections of both the first and second light-shielding structures onto the display panel are within the non-display region.

Abstract: Disclosed herein are compounds that inhibit KRas G12C, pharmaceutical compositions, methods of preparation and uses thereof.

Abstract: An optical film includes a polarizer. The polarizer includes a base layer, and a material of the base layer is obtained by dyeing a base material with a dye. The base material includes a polyvinyl alcohol material, and the dye is selected from blue dichroism organic dyes.

Abstract: Methods and systems for image processing are provided. Image data may be obtained. The image data may include a plurality of voxels corresponding to a first plurality of ribs of an object. A first plurality of seed points may be identified for the first plurality of ribs. The first plurality of identified seed points may be labelled to obtain labelled seed points. A connected domain of a target rib of the first plurality of ribs may be determined based on at least one rib segmentation algorithm. A labelled target rib may be obtained by labelling, based on a hit-or-miss operation, the connected domain of the target rib, wherein the hit-or-miss operation may be performed using the labelled seed points to hit the connected domain of the target rib.

Abstract: Provided are a supporting backplane and a display apparatus. The supporting backplane is arranged at one side of a flexible display panel, and the supporting backplane at least comprises a main bending area, wherein a bending axis corresponding to the main bending area extends in a first direction; the main bending area is provided with a plurality of first hollow holes, the plurality of first hollow holes being arranged in an array in the first direction and a second direction, which is orthogonal to the first direction; each of the first hollow holes is provided with a first middle hole area, and first arc-shaped hole areas located at two sides of the first middle hole area in the first direction.

Abstract: The present disclosure relates to the technical field of display product preparation, and in particular discloses a flexible display panel lamination device which is used for laminating a to-be-laminated flexible display panel onto a cover plate, and includes a base and an elastic lamination part arranged on the base. The elastic lamination part is provided with a first surface for bearing the to-be-laminated flexible display panel and a second surface opposite to the first surface; the second surface is symmetrically provided with two supporting protruding ribs; the two supporting protruding ribs are respectively fixed in two fixation grooves formed on the base; a gap is formed between a portion, located between the two supporting protruding ribs, of the second surface of the elastic lamination part and the base; and a portion, close to the edge, of the second surface of the elastic lamination part is supported on the base.

Abstract: The present disclosure provides computer-aided diagnosis systems and methods. The method may include obtaining multiple medical images of one or more bones; for at least one of the multiple medical images, detecting one or more bone fracture regions of the one or more bones in the medical image; causing a management list to be displayed for managing the one or more bones; receiving an instruction related to selecting at least one of the one or more bones, the instruction being generated through the management list; and upon receiving the instruction, causing the following to be displayed: at least one of one or more reconstructed bone images related to the at least one selected bone; or a marker of the one or more detected bone fracture regions related to the at least one selected bone.

Abstract: The present disclosure provides a smart glass and a light adjusting method, a light adjusting device and a non-transitory computer storage medium. The smart glass includes a first glass module, a touch control layer and a control unit. The first glass module includes a first substrate and a second substrate opposite to each other, and a first light adjusting layer between the first and second substrates. The light transmittance of the first light adjusting layer is adjusted by an electric field between the first substrate and the second substrate. The touch control layer is provided in at least one of the first substrate and the second substrate. The control unit is electrically coupled to the touch control layer to receive a touch control signal output by the touch control layer and adjust the electric field between the first substrate and the second substrate according to the touch control signal.