Abstract: The present invention relates to novel, improved processes for the preparation of sodium glucose co-transporter 2 (SGLT-2) inhibitors and novel intermediates thereof. More particularly, the present invention relates to a novel, improved process for the preparation of gliflozin compounds such as empagliflozin and dapagliflozin, intermediates thereof. The product obtained from the processes of present invention may be amorphous or crystalline, or in the form of amorphous/crystalline solid dispersions/solutions with pharmaceutically acceptable polymers and preparation process thereof. Also, the products obtained from the present invention may be used for the preparation of medicaments for the prevention and/or treatment of diseases and conditions associated with SGLT-2 inhibition.

Abstract: Disclosed are techniques for implementing three-dimensional or multi-layer integrated circuit designs. These techniques identify an electronic design and a plurality of inputs for implementing connectivity for the electronic design. Net distribution results may be generated at least by performing one or more net distribution analyzes. A bump in a bump array may then be assigned to a net that connects a first layer and a second layer in the electronic design based in part or in whole upon the net distribution analysis results.

Abstract: A communication device is described comprising a transmitter configured to transmit data according to a retransmission protocol, a determiner configured to determine whether, for a transmission time scheduled according to the retransmission protocol, there was a transmission gap within a predetermined time interval before the transmission time or to determine whether there will be a transmission gap within a predetermined time interval after the transmission time and a controller configured to control the transmitter to perform an initial transmission of data or a retransmission of data according to the retransmission protocol at the transmission time based on the result of the determination.

Abstract: For an LED lighting application, overshoot-protection circuitry prevents an LED controller, such as a matrix lighting controller (MLC) that controls an array of LEDs, from falsely detecting an open-circuit condition in an LED controlled by the LED controller, by limiting the magnitude of an overshoot voltage (due to long-wire parasitic inductances) from occurring when a switch in the LED controller that is used to control the LED is turned off.

Abstract: In various example embodiments, a system and method for a Target Language Engine are presented. The Target Language Engine augments a synonym list in a base dictionary of a target language with one or more historical search queries previously submitted to search one or more listings in listing data. The Target Language Engine identifies a compound word and a plurality of words present in the listing data that have a common meaning in the target language. Each word from the plurality of words is present in the compound word. The Target Language Engine causes a database to create an associative link between the portion of text and a word selected from at least one of the synonym list or the plurality of words.

Abstract: Various examples are directed to systems and methods for communications security. For example, a computing device may generate a connection between the computing device and a client device. A first application executing at the computing device may send a first application session key to the client device via the connection. The first application may perform a cryptographic operation on a first message based at least in part on the first application session key to generate a first cryptographic result and send the first cryptographic result to the client device via the connection. The first application may receive a second cryptographic result from the client device via the connection and determine that the second cryptographic result was obtained with the first application session key.

Abstract: Systems, methods and media are provided for training a snippet extractor to create snippets based on information extracted from published descriptions. In one example, a computer-implemented method includes creating, based on a non-RNN (Recurrent Neural Network) extraction technique performed on the published descriptions, a plurality of base models, each base model including one or more sample description summaries; evaluating the base models using an evaluation technique; selecting an optimum base model; developing a classification model using RNN extraction, the classification model based on description summaries contained in the optimum base model; and using the classification model to train the snippet extractor by machine learning.

Abstract: Systems and methods enabling the recording of a wide variety of online media for storage and later consumption are disclosed. The media can include audio, video, images, text and multi-media. The stored recordings can be played on internet-enabled devise such as televisions, mobile phones, personal computers, tablets, game systems, or the like. Recording is optionally accomplished using distributed recorders each making use of a virtualized browser.

Abstract: A communication device is described comprising a transmitter configured to transmit data according to a retransmission protocol, a determiner configured to determine whether, for a transmission time scheduled according to the retransmission protocol, there was a transmission gap within a predetermined time interval before the transmission time or to determine whether there will be a transmission gap within a predetermined time interval after the transmission time and a controller configured to control the transmitter to perform an initial transmission of data or a retransmission of data according to the retransmission protocol at the transmission time based on the result of the determination.

Abstract: A method includes receiving a signal indicative that a first access point can transmit data over a first number of spatial streams, and a second access point can transmit data over a second number of spatial streams. The method includes receiving a probe request from a set of client devices. A first portion of the set of client devices is configured to transmit data over the first number of spatial streams and a second portion of the client devices is configured to transmit data over the second number of spatial streams. The method includes sending a signal to the first portion associated with authorizing the first portion to connect to the first access point and sending a signal to the second portion associated with authorizing the second portion to connect to the second access point.

Abstract: A process for substantially reducing levels of circulating chromatin fragments (CCFs) from a medium using binding agents such as antibodies or antibodies complexed with haemocompatible natural polymer substrates like as alginates, chitosan and pullulan to form complexed antibodysubstrate nano-particulates (CNP) to bind and/or inactivate CCFs is disclosed. The amount of antibody bound to the polymer varies from 30% to 100% of activated sites in the polymer. Elevated levels of CCFs can be substantially reduced following administration of tissue damaging agents that generate apoptotic chromatin fragments by the concomitant administration of CNPs or concomitant administration of H4 antibody alone. A method of treatment is disclosed wherein therapeutic dose of CNPs, or H4 antibody alone, are administered systematically, or orally, in a delivery system to curb pathological conditions that are associated with increased burden of circulating chromatin fragments.

Abstract: A process for substantially reducing levels of circulating chromatin fragments (CCFs) from a medium using binding agents such as antibodies or antibodies complexed with haemocompatible natural polymer substrates like as alginates, chitosan and pullulan to form complexed antibody-substrate nano-particulates (CNP) to bind and/or inactivate CCFs is disclosed. The amount of antibody bound to the polymer varies from 30% to 100% of activated sites in the polymer. Elevated levels of CCFs can be substantially reduced following administration of tissue damaging agents that generate apoptotic chromatin fragments by the concomitant administration of CNPs or concomitant administration of H4 antibody alone. A method of treatment is disclosed wherein therapeutic dose of CNPs, or H4 antibody alone, are administered systematically, or orally, in a delivery system to curb pathological conditions that are associated with increased burden of circulating chromatin fragments.

Abstract: A method for estimating channel state information (CSI) for a communication channel is disclosed. Theoretical channel capacities are calculated using combinations of rank indicator (RI) and precoding matrix index (PMI) values. A number of these theoretical channel capacities are selected and used for determining an optimum combination of channel quality indicator (CQI) values, RI values and PMI values. This combination of values is subsequently transmitted as CSI.

Abstract: A method for estimating channel state information (CSI) for a communication channel is disclosed. Theoretical channel capacities are calculated using combinations of rank indicator (RI) and precoding matrix index (PMI) values. A number of these theoretical channel capacities are selected and used for determining an optimum combination of channel quality indicator (CQI) values, RI values and PMI values. This combination of values is subsequently transmitted as CSI.

Abstract: Systems and methods enabling the recording of a wide variety of online media for storage and later consumption are disclosed. The media can include audio, video, images, text and multi-media. The stored recordings can be played on internet-enabled devise such as televisions, mobile phones, personal computers, tablets, game systems, or the like. Recording is optionally accomplished using distributed recorders each making use of a virtualized browser.

Abstract: A process for substantially reducing levels of circulating chromatin fragments (CCFs) from a medium using binding agents such as antibodies or antibodies complexed with haemocompatible natural polymer substrates like as alginates, chitosan and pullulan to form complexed antibody-substrate nano-particulates (CNP) to bind and/or inactivate CCFs is disclosed. The amount of antibody bound to the polymer varies from 30% to 100% of activated sites in the polymer. Elevated levels of CCFs can be substantially reduced following administration of tissue damaging agents that generate apoptotic chromatin fragments by the concomitant administration of CNPs or concomitant administration of H4 antibody alone. A method of treatment is disclosed wherein therapeutic dose of CNPs, or H4 antibody alone, are administered systematically, or orally, in a delivery system to curb pathological conditions that are associated with increased burden of circulating chromatin fragments.

Abstract: Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of pregabalin in high yield and purity. The present invention also provides a process for the purification of (S)-pregabalin.

Abstract: The invention provides a method, a system and a computer program product for managing the data of Electronic Design Automation (EDA) tools in data processing units. This data is managed by a database management system. Data entries that are added to a database are sorted, compressed and stored. These data entries can be easily retrieved from the database that is based on a retrieval key.

Abstract: Disclosed is a leaded motor fuel additive composition which synergistically interacts with the alkyl lead additive to reduce both fuel intake system deposit formation and combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance.

Abstract: Disclosed is a MMT containing motor fuel additive composition which synergistically interacts with the MMT additive to reduce both fuel intake system deposit formation and combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance.