Abstract: A sustained release preparation of a human growth hormone conjugate is disclosed. The sustained release preparation contains a sustained release human growth hormone (hGH) conjugate resulting from conjugation between an immunoglobulin Fc region and a human growth hormone (hGH) as an active peptide; a buffer solution; a nonionic surfactant; and a sugar alcohol. A freeze dried preparation and a liquid preparation including the sustained release human growth hormone conjugate, a production method for the freeze dried preparation, a method of reconstituting the freeze dried preparation, and a kit containing the freeze dried preparation and a reconstituting solution are also disclosed.

Abstract: A semiconductor device comprising: a first or a second path configured to transmit a first signal which swings between a ground level and a first level, a third path configured to transmit a second signal which swings between the ground level and a second level lower than the first level, a transmitter configured to output received the first signal through the first or second path as the second signal to the third path, and initialize in response to an enable signal, and a receiver configured to output received the second signal through the third path as the first signal through the first or second path, determine level of the second signal through a reference level that is regulated according to a fed-back level of an output terminal thereof, and initialize in response to the enable signal.

Abstract: Disclosed is a method of managing data by an electronic apparatus, the method including identifying catalog data related to an item, generating target data corresponding to one or more target servers based on the catalog data, generating feed data corresponding to the one or more target servers at intervals of a preset period based on the target data, and transmitting the generated feed data to a corresponding target server.

Abstract: The present invention relates to a sintering-resistant metal catalyst supported on a single-atomic Ce-doped metal oxide and use thereof, and more particularly to a sintering-resistant metal catalyst, a method for preparing same, and use thereof, wherein the metal catalyst has improved resistance to sintering while maintaining metallicity of the metal even in high temperature thermochemical reaction by including an active metal component in a metal oxide carrier doped with single atomic sized Ce. The metal catalyst has improved resistance to sintering while maintaining metallicity of the active metal, and thus exhibits excellent catalytic performance in a high-temperature thermochemical reaction, such as aromatization, dehydrogenation or hydrogenation of hydrocarbons.

Abstract: Polyethylene glycol derivatives of the following formula I and uses thereof are disclosed. A method for manufacturing the polyethylene glycol derivatives is also disclosed.

Abstract: Proposed is a stand-alone enclosure that integrates an immersion thermal management system and a battery. More particularly, proposed is an immersion cooling battery system integrated with an enclosure, which is a battery system integrated with an immersion method that complements various shortcomings of a battery system using the immersion method, thereby reducing production costs, simplifying manufacturing, easing maintenance and repair, enabling efficient thermal management, and securing high fire safety, wherein the battery system enables battery operation regardless of external environmental conditions and is designed to prevent surrounding environmental pollution due to leakage of a fluid, an immersion cooling medium.

Abstract: The present invention relates to fire-extinguishing equipment integrated with a secondary battery system for early detection and early extinguishing for reducing the risk of fire spreading inside battery modules, and, more specifically, the present invention comprises: a plurality of battery modules constituting a secondary battery system; module unit fire detection devices mounted inside the modules so as to sense a fire in advance; and integrated fire extinguishing equipment partially coupled to the battery modules so as to directly spray a fire extinguishing agent at the inside of each module, wherein the battery modules include additional members for a cooling effect and the instantaneously supply of a fire-extinguishing agent when a fire is detected.

Abstract: The present invention relates to fire-extinguishing equipment integrated with a secondary battery system for early detection and early extinguishing for reducing the risk of fire spreading inside battery modules, and, more specifically, the present invention comprises: a plurality of battery modules constituting a secondary battery system; module unit fire detection devices mounted inside the modules so as to sense a fire in advance; and integrated fire extinguishing equipment partially coupled to the battery modules so as to directly spray a fire extinguishing agent at the inside of each module, wherein the battery modules include additional members for a cooling effect and the instantaneously supply of a fire-extinguishing agent when a fire is detected.

Abstract: The present invention relates to a novel peptide of a glucagon derivative and a composition for preventing or treating obesity comprising the peptide as an active ingredient. The glucagon derivative according to the present invention shows a more excellent activating effect with regard to both glucagon-like peptide-1 receptors and glucagon receptors compared to native glucagon, and thus can be widely used as an effective agent for treating obesity.

Abstract: A semiconductor device comprising: a first or a second path configured to transmit a first signal which swings between a ground level and a first level, a third path configured to transmit a second signal which swings between the ground level and a second level lower than the first level, a transmitter configured to output received the first signal through the first or second path as the second signal to the third path, and initialize in response to an enable signal, and a receiver configured to output received the second signal through the third path as the first signal through the first or second path, determine level of the second signal through a reference level that is regulated according to a fed-back level of an output terminal thereof, and initialize in response to the enable signal.

Abstract: A semiconductor device comprises: a first or a second path configured to transmit a first signal which swings between a ground level and a first level, a third path configured to transmit a second signal which swings between the ground level and a second level lower than the first level, a transmitter configured to output received the first signal through the first or second path as the second signal to the third path, and initialize in response to an enable signal, and a receiver configured to output received the second signal through the third path as the first signal through the first or second path, determine level of the second signal through a reference level that is regulated according to a fed-back level of an output terminal thereof, and initialize in response to the enable signal.

Abstract: A duty correction device includes a clock generation circuit, first and second correction pulse generation circuits, and a duty correction circuit. The clock generation circuit generates first to third divided clock signals, each having a phase offset from a reference clock signal. The first correction pulse generation circuit generates a first correction pulse by detecting a phase difference between a delayed clock signal and the first and second divided clock signals. The second correction pulse generation circuit generates a second correction pulse by detecting a phase difference between the second and third divided clock signals. The duty correction circuit checks whether the first and second correction pulses are generated at a preset logic level of the reference clock signal, and reflects the first or second correction pulses in a duty correction operation for the reference clock signal according to a result of the check.

Abstract: The present invention relates to a conjugate comprising oxyntomodulin, an immunoglobulin Fc region, and non-peptidyl polymer wherein the conjugate being obtainable by covalently linking oxyntomodulin to immunoglobulin Fc region via non-peptidyl polymer, and a pharmaceutical composition for the prevention or treatment of obesity comprising the conjugates. The conjugate comprising oxyntomodulin and the immunoglobulin Fc of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis without side-effects, unlike native oxyntomodulin, and also shows excellent receptor-activating effects and long-term sustainability, compared to native oxyntomodulin. Thus, it can be widely used in the treatment of obesity with safety and efficacy.

Abstract: A stacked integrated circuit includes a first chip including a first through via set and a second through via set that are disposed to be symmetrical to each other in relation to a first rotating axis and including a first input and output (IO) circuit and a second IO circuit that are disposed to be asymmetrical to each other in relation to the first rotating axis and a second chip including a third through via set and a fourth through via set that are disposed to be symmetrical to each other in relation to a second rotating axis and including a third IO circuit and a fourth IO circuit that are disposed to be asymmetrical to each other in relation to the second rotating axis, the second chip being rotated around the second rotating axis and stacked on the first chip.

Abstract: The present invention relates to an insulin analog conjugate and use thereof.

Abstract: An integrated circuit (IC) chip includes a plurality of interlayer channels; at least one data pad; an identification (ID) generation circuit suitable for generating a chip ID signal by decoding a command/address signal; a first transmission circuit suitable for transferring a plurality of internal data pieces to a transmission path by aligning a plurality of interlayer data pieces respectively transferred from the plurality of interlayer channels according to a plurality of strobe signals while selectively inverting the plurality of interlayer data pieces according to the chip ID signal; and a second transmission circuit suitable for transferring the plurality of internal data pieces from the transmission path to the at least one data pad.

Abstract: A method for improving the solubility of a physiologically active protein or peptide compared to that of a physiologically active protein or peptide which is not conjugated to an immunoglobulin Fc fragment is disclosed. The method includes steps of conjugating the physiologically active protein or peptide to an immunoglobulin Fc fragment. Also disclosed is a composition for improving the solubility of a physiologically active protein or peptide, which contains an immunoglobulin Fc fragment. The composition improves the solubility compared to a composition without an immunoglobulin Fc fragment.

Abstract: Polyethylene glycol derivatives of the following formula I and uses thereof are disclosed. A method for manufacturing the polyethylene glycol derivatives is also disclosed.

Abstract: A sound absorption device and a method of manufacturing the same are provided. The sound absorption device includes a sound absorbing panel including first elements, second elements, third elements, and fourth elements arranged in different directions, wherein a cross-section of at least one of the first through fourth elements has a distorted circular shape, a distorted polygonal shape, or a distorted elliptical shape.

Abstract: An integrated circuit (IC) chip includes a plurality of interlayer channels; at least one data pad; an identification (ID) generation circuit suitable for generating a chip ID signal by decoding a command/address signal; a first transmission circuit suitable for transferring a plurality of internal data pieces to a transmission path by aligning a plurality of interlayer data pieces respectively transferred from the plurality of interlayer channels according to a plurality of strobe signals while selectively inverting the plurality of interlayer data pieces according to the chip ID signal; and a second transmission circuit suitable for transferring the plurality of internal data pieces from the transmission path to the at least one data pad.