Patents by Inventor Chang Shao

Chang Shao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11961946
    Abstract: A foldable electronic device may have a foldable housing. The foldable housing may be configured to bend about a bend axis. First and second portions of the housing that rotate relative to each other may be coupled by a hinge that is aligned with the bend axis. A foldable display may be coupled to the foldable housing and may be configured to bend along the bend axis as the foldable housing is folded. The display may have an array of pixels supported by a metal layer. The pixels may be interposed between a display cover layer and the metal layer. The foldable housing may have a support layer. To help support the display for bending about the bend axis while preventing damage to the display when the display is contacted by an external object, a spring layer may be interposed between the metal layer and the support layer.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: April 16, 2024
    Assignee: Apple Inc.
    Inventors: Chang-Chia Huang, Hoon Sik Kim, Paul S. Drzaic, Terry C. Lam, Yasmin F. Afsar, Zhichun Shao
  • Publication number: 20240077885
    Abstract: A self-moving device, including: a moving module, a task execution module, a control module. The control module is electrically connected to the moving module and the task execution module, controls the moving module to actuate the self-moving device to move, controls the task execution module to execute a working task. The self-moving device further includes a satellite navigation apparatus, electrically connected to the control module and configured to receive a satellite signal and output current location information of the self-moving device. The control module determines whether quality of location information output by the satellite navigation apparatus at a current location satisfies a preset condition, controls, if the quality does not satisfy the preset condition, the moving module to actuate the self-moving device to change a moving manner, to enable quality of location information output by the satellite navigation apparatus at a location after the movement to satisfy the preset condition.
    Type: Application
    Filed: November 10, 2023
    Publication date: March 7, 2024
    Inventors: Yong Shao, Mingming He, Chang Zhou, Zhou Yang, Gen Sun, Yue Rao
  • Patent number: 11696937
    Abstract: The present invention discloses glycopeptide compounds having activity of resisting drug-resistant bacteria, conforming to glycopeptide compounds represented by general formula (I), The present invention also provides a preparation method for and an application of the glycopeptide compounds. Upon testing, compared with a second-generation glycopeptide drug oritavancin, the glycopeptide antibiotic compounds have higher inhibition activity on drug-resistant bacterial strains, especially MRSA or VRE. Further testing shows that most of the glycopeptide compounds have safety higher than that of oritavancin and can be prepared into drugs for treating or preventing diseases caused by various bacterial infections, such as skin and soft tissue infections, meningitis, sepsis, pneumonia, arthritis, peritonitis, bronchitis, and empyema.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: July 11, 2023
    Assignees: Shanghai LaiYi Center For Biopharmaceutical R&D Co., Ltd., Zhejiang Medicine Co., Ltd.
    Inventors: Chang Shao, Mei Ge, Lingao Ruan, Wei Wei, Xing Xia, Min Rao, Qingqian Meng, Minyu Luo
  • Publication number: 20220331366
    Abstract: The present invention provides a novel repair agent for damaged tissue that brings about a notably high effect of repairing damaged tissue, as compared with conventional repair agents for damaged tissue, and a method for producing such a repair agent. A method for producing a repair agent for damaged tissue of the present invention includes the step of culturing mesenchymal stem cells in a serum-free medium at an oxygen concentration of less than 5%.
    Type: Application
    Filed: September 25, 2020
    Publication date: October 20, 2022
    Inventors: Yukio KATO, Satoshi MAEDA, Koichiro TSUJI, Jin Chang SHAO, Ayumu NAKASHIMA, Takao MASAKI, Shigehiro DOI, Naoki ISHIUCHI
  • Publication number: 20210261902
    Abstract: Provided is a simple, safe warming method which causes no or little damage to a biological sample. A method of warming a biological sample includes the steps of: i) putting a biological sample container (5) into a heat medium container (2), the biological sample container (5) having a biological sample disposed therein, the heat medium container (2) having a heat medium (4) disposed therein; and thereafter ii) closing an inlet (3) of the heat medium container (2), the inlet being an inlet through which the heat medium (4) is injected into the heat medium container (2); and iii) moving the heat medium (4) by moving the heat medium container (2) with the inlet (3) closed.
    Type: Application
    Filed: June 28, 2019
    Publication date: August 26, 2021
    Inventors: Shunsuke TANIGAWA, Masanori NAKASA, Jin Chang SHAO, Yukio KATO
  • Publication number: 20210093691
    Abstract: The present invention discloses glycopeptide compounds having activity of resisting drug-resistant bacteria, conforming to glycopeptide compounds represented by general formula (I), The present invention also provides a preparation method for and an application of the glycopeptide compounds. Upon testing, compared with a second-generation glycopeptide drug oritavancin, the glycopeptide antibiotic compounds have higher inhibition activity on drug-resistant bacterial strains, especially MRSA or VRE. Further testing shows that most of the glycopeptide compounds have safety higher than that of oritavancin and can be prepared into drugs for treating or preventing diseases caused by various bacterial infections, such as skin and soft tissue infections, meningitis, sepsis, pneumonia, arthritis, peritonitis, bronchitis, and empyema.
    Type: Application
    Filed: March 4, 2019
    Publication date: April 1, 2021
    Inventors: Chang SHAO, Mei GE, Lingao RUAN, Wei WEI, Xing XIA, Min RAO, Qingqian MENG, Minyu LUO
  • Publication number: 20200205399
    Abstract: An object is to achieve cryopreservation that yields no or few dead cells and that ensures good quality. A composition for cryopreservation in accordance with an aspect of the present invention is a composition for cryopreservation of cells, and contains a fatty acid.
    Type: Application
    Filed: July 31, 2018
    Publication date: July 2, 2020
    Inventors: Jin Chang SHAO, Shunsuke TANIGAWA, Masanori NAKASA, Yukio KATO, Koichiro TSUJI, Akihiro OHISO
  • Patent number: 10507266
    Abstract: A method according to the present invention for producing a cartilage-damage treatment agent, includes the steps of: (i) proliferating mesenchymal stem cells in a serum-free medium A containing an FGF, a PDGF, a TGF-?, an HGF, an EGF, at least one phospholipid and at least one fatty acid; and (ii) mixing the mesenchymal stem cells thus proliferated in the step (i), an isotonic preserving agent, and a cytoprotective agent. This method provides a cartilage-damage treatment agent which favorably regenerates a cartilage tissue.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: December 17, 2019
    Assignee: TWO CELLS Co., Ltd.
    Inventors: Koichiro Tsuji, Minoru Morikawa, Satoshi Maeda, Yui Kitayama, Aki Ohmori, Jin Chang Shao, Shinichi Hasegawa, Yukio Kato, Takashi Matsushita, Masato Takao, Shinya Miki, Ken Innami, Yasufumi Takahashi
  • Patent number: 10184112
    Abstract: Disclosed are: a culture medium containing a specific growth factor and at least one phospholipid; a composition for preparation of the culture medium; a kit; and a method. A technique can be provided which uses a serum-free or low-serum culture medium and has a promoting effect on the proliferation of an animal cell comparable to the promoting effect obtained by the culture in a serum-containing culture medium.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: January 22, 2019
    Assignee: Two Cells Co., Ltd.
    Inventors: Yukio Kato, Jin Chang Shao, Yuki Katsura, Koichiro Tsuji
  • Patent number: 10131877
    Abstract: Provided is a differentiation-inducing culture medium additive for inducing bone differentiation of at least one type of cell selected from the group consisting of a stem cell, a dental pulp cell, a periodontal ligament cell, a placenta, an amnion, and a fibroblast under a serum-free condition, and a use of the differentiation-inducing culture medium additive. The differentiation-inducing culture medium additive of the present invention for inducing differentiation of a stem cell under a serum-free condition at least contains at least one growth factor selected from the group consisting of EGF, FGF, and PDGF; dexamethasone; and ?-glycerophosphate. The differentiation-inducing culture medium additive of the present invention does not require ascorbic acid 2-phosphate and ITS, which are normally essential for bone differentiation. Further, bone differentiation can be promoted by adding phospholipid.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: November 20, 2018
    Assignee: TWO CELLS Co., Ltd.
    Inventors: Yukio Kato, Jin Chang Shao, Koichiro Tsuji
  • Patent number: 9982019
    Abstract: The present invention provides a glycopeptide compound or pharmaceutically acceptable salt thereof as shown in Formula (I) or (II), and a method for preparing same, and pharmaceutical compositions and applications thereof, wherein the definition of R1, R2, R3, R4, R5 is the same as that of the specification. The glycopeptide compound of the present invention has in-vitro antibacterial activity and has important significance for development of new antibacterial agents.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: May 29, 2018
    Inventors: Dingfeng Zhang, Yuanyuan Ge, Mei Ge, Weicheng Zhou, Wei Wei, Shunli Zhang, Lingao Ruan, Zhenren Liu, Chang Shao
  • Publication number: 20170105519
    Abstract: A stand includes a frame and a base. The frame includes a hook, a main body and a pivoting part. The main body is connected between the hook and the pivoting part. The hook has a groove, allowing the frame to be rotated relative to a rod by taking an extending direction of the groove as an axis of rotation. The base is pivoted to the pivoting part, allowing the base to be folded or unfolded relative to the frame so as to adjust an angle between the base and the main body of the frame.
    Type: Application
    Filed: April 19, 2016
    Publication date: April 20, 2017
    Inventors: Jiun-Hong WANG, Pei-Ju TSAI, Chieh LAI, Kaun-Chang SHAO
  • Patent number: 9394521
    Abstract: A cell preparation containing mesenchymal stem cells whose immunosuppression ability is maintained is produced by means of a serum-free or low-serum culture. A method for producing a cell preparation containing mesenchymal stem cells, comprising the steps of: (A) proliferating mesenchymal stem cells in a serum-free medium “A” containing an FGF, a PDGF, a TGF-?, an HGF, an EGF, at least one phospholipid, and at least one fatty acid; and (B) screening mesenchymal stem cells whose immunosuppression ability is maintained or improved, from the mesenchymal stem cells thus proliferated in the step (A).
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: July 19, 2016
    Assignee: TWO CELLS Co., Ltd.
    Inventors: Toshie Tsuchiya, Koichiro Tsuji, Yukio Kato, Jin Chang Shao, Maiko Hara
  • Publication number: 20160166734
    Abstract: A method according to the present invention for producing a cartilage-damage treatment agent, includes the steps of: (i) proliferating mesenchymal stem cells in a serum-free medium A containing an FGF, a PDGF, a TGF-?, an HGF, an EGF, at least one phospholipid and at least one fatty acid; and (ii) mixing the mesenchymal stem cells thus proliferated in the step (i), an isotonic preserving agent, and a cytoprotective agent. This method provides a cartilage-damage treatment agent which favorably regenerates a cartilage tissue.
    Type: Application
    Filed: August 1, 2014
    Publication date: June 16, 2016
    Inventors: Koichiro TSUJI, Minoru MORIKAWA, Satoshi MAEDA, Yui KITAYAMA, Aki OHMORI, Jin Chang SHAO, Shinichi HASEGAWA, Yukio KATO, Takashi MATSUSHITA, Masato TAKAO, Shinya MIKI, Ken INNAMI, Yasufumi TAKAHASHI
  • Publication number: 20160032247
    Abstract: Provided is a differentiation-inducing culture medium additive for inducing bone differentiation of at least one type of cell selected from the group consisting of a stem cell, a dental pulp cell, a periodontal ligament cell, a placenta, an amnion, and a fibroblast under a serum-free condition, and a use of the differentiation-inducing culture medium additive. The differentiation-inducing culture medium additive of the present invention for inducing differentiation of a stem cell under a serum-free condition at least contains at least one growth factor selected from the group consisting of EGF, FGF, and PDGF; dexamethasone; and ?-glycerophosphate. The differentiation-inducing culture medium additive of the present invention does not require ascorbic acid 2-phosphate and ITS, which are normally essential for bone differentiation. Further, bone differentiation can be promoted by adding phospholipid.
    Type: Application
    Filed: October 16, 2015
    Publication date: February 4, 2016
    Inventors: Yukio KATO, Jin Chang SHAO, Koichiro Tsuji
  • Publication number: 20150353607
    Abstract: The present invention provides a glycopeptide compound or pharmaceutically acceptable salt thereof as shown in Formula (I) or (II), and a method for preparing same, and pharmaceutical compositions and applications thereof, wherein the definition of R1, R2, R3, R4, R5 is the same as that of the specification. The glycopeptide compound of the present invention has in-vitro antibacterial activity and has important significance for development of new antibacterial agents.
    Type: Application
    Filed: December 26, 2013
    Publication date: December 10, 2015
    Inventors: Dingfeng Zhang, Yuanyuan Ge, Mei Ge, Weicheng Zhou, Wei Wei, Shunli Zhang, Lingao Ruan, Zhenren Liu, Chang Shao
  • Publication number: 20150267172
    Abstract: Disclosed are: a culture medium containing a specific growth factor and at least one phospholipid; a composition for preparation of the culture medium; a kit; and a method. A technique can be provided which uses a serum-free or low-serum culture medium and has a promoting effect on the proliferation of an animal cell comparable to the promoting effect obtained by the culture in a serum-containing culture medium.
    Type: Application
    Filed: May 29, 2015
    Publication date: September 24, 2015
    Inventors: Yukio KATO, Jin Chang SHAO, Yuki KATSURA, Koichiro TSUJI
  • Patent number: 9074176
    Abstract: Disclosed are: a culture medium containing a specific growth factor and at least one phospholipid; a composition for preparation of the culture medium; a kit; and a method. A technique can be provided which uses a serum-free or low-serum culture medium and has a promoting effect on the proliferation of an animal cell comparable to the promoting effect obtained by the culture in a serum-containing culture medium.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: July 7, 2015
    Assignee: Two Cells Co., Ltd.
    Inventors: Yukio Kato, Jin Chang Shao, Yuki Katsura, Koichiro Tsuji
  • Patent number: 8400763
    Abstract: A display device includes a front frame, a panel module, a main back cover, a sub-back cover, a circuit device and a stand set, wherein the main back cover includes a recess portion sinking from the main back cover toward the panel module. An inner space is formed between the recess portion and the sub-back cover. The circuit device is disposed in the inner space and connected to the recess portion. In different embodiments, the display device includes a reinforcing rib for grounding purpose. The reinforcing rib is disposed on the panel module and is located between the panel module and the main back cover. Furthermore, a through-hole is formed on the recess portion for the reinforcing rib to pass through and electrically couples with the circuit device.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: March 19, 2013
    Assignee: AU Optronics Corporation
    Inventors: Chung-Min Wang, Kuan-Chang Shao, Chien-Fu Chen
  • Publication number: 20120329087
    Abstract: A cell preparation containing mesenchymal stem cells whose immunosuppression ability is maintained is produced by means of a serum-free or low-serum culture. A method for producing a cell preparation containing mesenchymal stem cells, comprising the steps of: (A) proliferating mesenchymal stem cells in a serum-free medium “A” containing an FGF, a PDGF, a TGF-?, an HGF, an EGF, at least one phospholipid, and at least one fatty acid; and (B) screening mesenchymal stem cells whose immunosuppression ability is maintained or improved, from the mesenchymal stem cells thus proliferated in the step (A).
    Type: Application
    Filed: March 10, 2011
    Publication date: December 27, 2012
    Applicant: TWO CELLS CO., LTD.
    Inventors: Toshie Tsuchiya, Koichiro Tsuji, Yukio Kato, Jin Chang Shao, Maiko Hara