Patents by Inventor Chang-Yu Chen
Chang-Yu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250084822Abstract: A remote-controlled modular hydropower generator system, comprising: a turbine module, a gear box module, a transmission module, a power generator module, a monitoring module, and a wireless communication module. The wireless communication module can transmit hydropower generator data from the monitoring module to a remote control module, enabling real-time monitoring of the hydropower generator data from the power generator module. The remote control module can send control commands to the monitoring module through the wireless communication module to control the power generator module. The turbine housing is securely fastened using two main frames and an intermediate divider, allowing for quick disassembly, maintenance, or replacement of the turbine and gear box module. The transmission module and the power generator module are locked on the outer sides of the two main frames, facilitating fast disassembly, maintenance, or replacement of the transmission module and the power generator module.Type: ApplicationFiled: September 5, 2024Publication date: March 13, 2025Inventor: CHANG-YU CHEN
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Publication number: 20240118528Abstract: A microscope device for observing a sample. The microscope device and the sample are located on an optical route. The microscope device includes an objective lens unit and an additional light source set. The light source set includes a circuit substrate, a battery and a light-emitting unit. The circuit substrate has a power source portion and a light source portion electrically connected to the power source portion. A connecting member and the battery are arranged at opposite sides of the power source portion. The light-emitting unit is arranged on the light source portion, and the distance between the light-emitting unit and the center axis of the optical route is greater than the radius of the objective lens unit. The battery activates the light-emitting unit to generate a light beam, and the light beam irradiates toward the center axis of the optical route.Type: ApplicationFiled: October 6, 2023Publication date: April 11, 2024Inventors: Chang-Ching YEH, Chang-Yu CHEN, Shu-Sheng LIN
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Patent number: 11919932Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: GrantFiled: January 3, 2023Date of Patent: March 5, 2024Assignees: THE UNIVERSITY OF TOKYO, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji Matsushima, Satoshi Ueha, Shungo Deshimaru, Chang-Yu Chen, Shoji Yokochi, Yoshiro Ishiwata, Shiro Shibayama
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Publication number: 20230393378Abstract: A micro distance adjusting mechanism includes a first element having a first body and a first screw-connecting portion, a second element having a second body and a second screw-connecting portion, and a connection member. The first body has a first through hole on an optical route, and the second body has a second through hole on the optical route. The objective lens unit is telescoped in the first and second through holes. The first screw-connecting portion is rotatably connected to the second screw-connecting portion, and the first and second bodies make a relative rotation range during the micro distance adjustment. The connection member is connected to the first body or the second body to limit the relative rotation range within 360 degrees and the range of the micro distance adjustment to 0.1 mm-3.5 mm.Type: ApplicationFiled: June 5, 2023Publication date: December 7, 2023Inventors: CHANG-YU CHEN, CHANG-CHING YEH
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Publication number: 20230220022Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: ApplicationFiled: January 3, 2023Publication date: July 13, 2023Applicants: The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji MATSUSHIMA, Satoshi UEHA, Shungo DESHIMARU, Chang-Yu CHEN, Shoji YOKOCHI, Yoshiro ISHIWATA, Shiro SHIBAYAMA
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Patent number: 11572393Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: GrantFiled: March 7, 2019Date of Patent: February 7, 2023Assignees: THE UNIVERSITY OF TOKYO, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji Matsushima, Satoshi Ueha, Shungo Deshimaru, Chang-Yu Chen, Shoji Yokochi, Yoshiro Ishiwata, Shiro Shibayama
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Publication number: 20200407408Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: ApplicationFiled: March 7, 2019Publication date: December 31, 2020Applicants: The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji MATSUSHIMA, Satoshi UEHA, Shungo DESHIMARU, Chang-Yu CHEN, Shoji YOKOCHI, Yoshiro ISHIWATA, Shiro SHIBAYAMA
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Patent number: 10578857Abstract: A portable microscope apparatus operated with an image capture device includes a sample carrying module, a lens module, a first polarizer and a second polarizer. The sample carrying module includes a transparent carrier and a sample adhesive element including a substrate and a glue layer. The substrate has a concave portion and an extending portion. The concave portion is adjacently connected to the extending portion to form a first surface. The glue layer is at least partially disposed on the first surface and in an integrated form with the substrate. The lens module is detachably connected to the image capture device, and disposed between the sample carrying module and the image capture device. The first polarizer is disposed on an optical path on one side of the sample carrying module. The second polarizer is disposed on the optical path on the other side of the sample carrying module.Type: GrantFiled: January 27, 2017Date of Patent: March 3, 2020Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
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Patent number: 10495868Abstract: A microscope apparatus includes a sample carrying module, a light source module and a lens module. The sample carrying module includes an adhesive element and a body having a light-transmission region and a sample viewing surface. The adhesive element is detachably adhered to the body, and at least partially covers the light-transmission region, such that the adhesive element is disposed adjacent to the sample viewing surface. The light source module is detachably disposed at a side of the body, and includes a base and a light source. The base has an aperture, and the sample carrying module is detachably disposed at a side of the aperture. The light source is disposed in the base. The lens module includes at least one lens, which is detachably disposed at one side of the sample carrying module and substantially focuses at the sample viewing surface, and corresponds to the light source module.Type: GrantFiled: January 26, 2017Date of Patent: December 3, 2019Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
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Patent number: 10495863Abstract: The present invention discloses a portable microscope device which can be installed on the smartphone capable of capturing image. By combing these devices, users can observe the detection sample and capture the image of the sample instantly without environment limitation. Moreover, during operation, the user can observe the whole image of the sample by substituting the microscope lens of different magnification ratio or by shifting the position of the sample.Type: GrantFiled: July 7, 2015Date of Patent: December 3, 2019Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Shu-Sheng Lin, Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang
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Patent number: 10362706Abstract: Examples herein relate to server systems with hinge mechanisms. In one example, a server system includes a first enclosure and a second enclosure, the first and second enclosure each include a front end and a back end disposed opposite to each other, the front end having an opening. The server system further includes a hinge mechanism, the hinge mechanism connecting an upper edge of the back end of the first enclosure to an upper edge of the front end of the second enclosure. The first enclosure is adapted to rotate around the hinge mechanism.Type: GrantFiled: April 19, 2017Date of Patent: July 23, 2019Assignee: Hewlett Packard Enterprise Development LPInventors: Geoffrey Sun, Chun-han Lin, Chang Yu Chen, Ku-Hsu Nien, Tse-Jen Sung
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Patent number: 10354271Abstract: An electronic device and a play and interactive method for an electronic advertising are provided. The electronic device includes a touch module, a display, a static information presentation structure and a data processing device. The touch module has a touch area for providing position of a measured object in the touch area. The display has a display area set in the touch area. The touch area is composed of the display area and a non-display area. The static information presentation structure is disposed on the non-display area. The data processing device determines whether the measured object performs a operation in the display area or the non-display area according to the position of the measured object provided by the touch module. When the operation is located in the non-display area, the data processing device displays a corresponding data in the display area according to position of the operation.Type: GrantFiled: October 6, 2016Date of Patent: July 16, 2019Assignee: AOPEN INC.Inventors: Chang-Yu Chen, Huei-Ju Liao
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Patent number: 10288869Abstract: A reflecting microscope module cooperating with an image capturing module includes a housing, a lens and a sample adhesive substance. The housing has a sample inspecting surface located on one side of the housing opposite to the image capturing module. The lens is disposed in the housing and the sample adhesive substance is detachably disposed on a bottom of the housing. The sample adhesive substance adjacently connected to the sample inspecting surface includes a substrate and a glue layer. The glue layer is integrally combined with the substrate to form one piece. A reflecting microscope device is also disclosed.Type: GrantFiled: January 31, 2017Date of Patent: May 14, 2019Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
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Patent number: 10281708Abstract: A microscope module, which is cooperated with an image capturing module, includes a housing, a convex lens and an illumination assembly. The housing has a sample inspecting surface located on one side of the housing, which is opposite to the image capturing module. The convex lens is disposed in the housing, and the shortest distance between the sample inspecting surface and the convex lens ranges from 0.1 mm to 3.0 mm. The illumination assembly has a light source and is located between the image capturing module and the convex lens. The light emitted from the light source enters the convex lens through an input surface of the convex lens, leaves the convex lens through an output surface of the convex lens, and then reaches the sample inspecting surface. A microscope device containing the microscope module is also disclosed.Type: GrantFiled: August 12, 2016Date of Patent: May 7, 2019Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Cheng-Ming Lin, Chang-Yu Chen, Shu-Sheng Lin, Tsun-Chao Chiang
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Publication number: 20180310427Abstract: Examples herein relate to server systems with hinge mechanisms. In one example, a server system includes a first enclosure and a second enclosure, the first and second enclosure each include a front end and a back end disposed opposite to each other, the front end having an opening. The server system further includes a hinge mechanism, the hinge mechanism connecting an upper edge of the back end of the first enclosure to an upper edge of the front end of the second enclosure. The first enclosure is adapted to rotate around the hinge mechanism.Type: ApplicationFiled: April 19, 2017Publication date: October 25, 2018Inventors: Geoffrey SUN, Chun-han LIN, Chang Yu CHEN, Ku-Hsu NIEN, Tse-Jen SUNG
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Patent number: 9900558Abstract: A microscope module includes a light source assembly, a sampling assembly and a diffusing element. The light source assembly includes a light source and a light guide element. The light source is disposed close to the light incidence end of the light guide element. The sampling assembly includes a cover and a base. The cover and the base are combined to define a sample accommodating space, which is located at the light exit end of the light guide element. The diffusing element is disposed between the light source and the sample accommodating space. The light emitted from the light source passes through the diffusing element and then enters the sample accommodating space. A microscope device containing the microscope module is also disclosed.Type: GrantFiled: October 23, 2015Date of Patent: February 20, 2018Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Cheng-Ming Lin, Shu-Sheng Lin, Chang-Yu Chen, Tsun-Chao Chiang
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Publication number: 20170344176Abstract: An electronic device and a play and interactive method for an electronic advertising are provided. The electronic device includes a touch module, a display, a static information presentation structure and a data processing device. The touch module has a touch area for providing position of a measured object in the touch area. The display has a display area set in the touch area. The touch area is composed of the display area and a non-display area. The static information presentation structure is disposed on the non-display area. The data processing device determines whether the measured object performs a operation in the display area or the non-display area according to the position of the measured object provided by the touch module. When the operation is located in the non-display area, the data processing device displays a corresponding data in the display area according to position of the operation.Type: ApplicationFiled: October 6, 2016Publication date: November 30, 2017Applicant: AOPEN INC.Inventors: Chang-Yu Chen, Huei-Ju Liao
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Publication number: 20170227757Abstract: A portable microscope apparatus operated with an image capture device includes a sample carrying module, a lens module, a first polarizer and a second polarizer. The sample carrying module includes a transparent carrier and a sample adhesive element including a substrate and a glue layer. The substrate has a concave portion and an extending portion. The concave portion is adjacently connected to the extending portion to form a first surface. The glue layer is at least partially disposed on the first surface and in an integrated form with the substrate. The lens module is detachably connected to the image capture device, and disposed between the sample carrying module and the image capture device. The first polarizer is disposed on an optical path on one side of the sample carrying module. The second polarizer is disposed on the optical path on the other side of the sample carrying module.Type: ApplicationFiled: January 27, 2017Publication date: August 10, 2017Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN
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Publication number: 20170227518Abstract: A sample detecting device is used in cooperation with an image capturing device. The sample detecting device includes a first assembly and a second assembly. The first assembly includes a light emitting unit and a light-permeable unit. The light-permeable unit is disposed at one side of the light emitting unit. The first assembly and the second assembly match and connect with each other to form a sample containing space. The second assembly includes a body and a convex lens. The body has a first cavity portion and a second cavity portion. The light-permeable unit is disposed in the first cavity portion, and the convex lens is disposed in the second cavity portion. The light emitted from the light emitting unit sequentially passes through the light-permeable unit and the convex lens and leaves the body.Type: ApplicationFiled: January 20, 2017Publication date: August 10, 2017Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN
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Publication number: 20170227758Abstract: A reflecting microscope module cooperating with an image capturing module includes a housing, a lens and a sample adhesive substance. The housing has a sample inspecting surface located on one side of the housing opposite to the image capturing module. The lens is disposed in the housing and the sample adhesive substance is detachably disposed on a bottom of the housing. The sample adhesive substance adjacently connected to the sample inspecting surface includes a substrate and a glue layer. The glue layer is integrally combined with the substrate to form one piece. A reflecting microscope device is also disclosed.Type: ApplicationFiled: January 31, 2017Publication date: August 10, 2017Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN