Patents by Inventor Chang-Yu Chen

Chang-Yu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250084822
    Abstract: A remote-controlled modular hydropower generator system, comprising: a turbine module, a gear box module, a transmission module, a power generator module, a monitoring module, and a wireless communication module. The wireless communication module can transmit hydropower generator data from the monitoring module to a remote control module, enabling real-time monitoring of the hydropower generator data from the power generator module. The remote control module can send control commands to the monitoring module through the wireless communication module to control the power generator module. The turbine housing is securely fastened using two main frames and an intermediate divider, allowing for quick disassembly, maintenance, or replacement of the turbine and gear box module. The transmission module and the power generator module are locked on the outer sides of the two main frames, facilitating fast disassembly, maintenance, or replacement of the transmission module and the power generator module.
    Type: Application
    Filed: September 5, 2024
    Publication date: March 13, 2025
    Inventor: CHANG-YU CHEN
  • Publication number: 20240118528
    Abstract: A microscope device for observing a sample. The microscope device and the sample are located on an optical route. The microscope device includes an objective lens unit and an additional light source set. The light source set includes a circuit substrate, a battery and a light-emitting unit. The circuit substrate has a power source portion and a light source portion electrically connected to the power source portion. A connecting member and the battery are arranged at opposite sides of the power source portion. The light-emitting unit is arranged on the light source portion, and the distance between the light-emitting unit and the center axis of the optical route is greater than the radius of the objective lens unit. The battery activates the light-emitting unit to generate a light beam, and the light beam irradiates toward the center axis of the optical route.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 11, 2024
    Inventors: Chang-Ching YEH, Chang-Yu CHEN, Shu-Sheng LIN
  • Patent number: 11919932
    Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.
    Type: Grant
    Filed: January 3, 2023
    Date of Patent: March 5, 2024
    Assignees: THE UNIVERSITY OF TOKYO, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kouji Matsushima, Satoshi Ueha, Shungo Deshimaru, Chang-Yu Chen, Shoji Yokochi, Yoshiro Ishiwata, Shiro Shibayama
  • Publication number: 20230393378
    Abstract: A micro distance adjusting mechanism includes a first element having a first body and a first screw-connecting portion, a second element having a second body and a second screw-connecting portion, and a connection member. The first body has a first through hole on an optical route, and the second body has a second through hole on the optical route. The objective lens unit is telescoped in the first and second through holes. The first screw-connecting portion is rotatably connected to the second screw-connecting portion, and the first and second bodies make a relative rotation range during the micro distance adjustment. The connection member is connected to the first body or the second body to limit the relative rotation range within 360 degrees and the range of the micro distance adjustment to 0.1 mm-3.5 mm.
    Type: Application
    Filed: June 5, 2023
    Publication date: December 7, 2023
    Inventors: CHANG-YU CHEN, CHANG-CHING YEH
  • Publication number: 20230220022
    Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.
    Type: Application
    Filed: January 3, 2023
    Publication date: July 13, 2023
    Applicants: The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kouji MATSUSHIMA, Satoshi UEHA, Shungo DESHIMARU, Chang-Yu CHEN, Shoji YOKOCHI, Yoshiro ISHIWATA, Shiro SHIBAYAMA
  • Patent number: 11572393
    Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: February 7, 2023
    Assignees: THE UNIVERSITY OF TOKYO, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kouji Matsushima, Satoshi Ueha, Shungo Deshimaru, Chang-Yu Chen, Shoji Yokochi, Yoshiro Ishiwata, Shiro Shibayama
  • Publication number: 20200407408
    Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.
    Type: Application
    Filed: March 7, 2019
    Publication date: December 31, 2020
    Applicants: The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kouji MATSUSHIMA, Satoshi UEHA, Shungo DESHIMARU, Chang-Yu CHEN, Shoji YOKOCHI, Yoshiro ISHIWATA, Shiro SHIBAYAMA
  • Patent number: 10578857
    Abstract: A portable microscope apparatus operated with an image capture device includes a sample carrying module, a lens module, a first polarizer and a second polarizer. The sample carrying module includes a transparent carrier and a sample adhesive element including a substrate and a glue layer. The substrate has a concave portion and an extending portion. The concave portion is adjacently connected to the extending portion to form a first surface. The glue layer is at least partially disposed on the first surface and in an integrated form with the substrate. The lens module is detachably connected to the image capture device, and disposed between the sample carrying module and the image capture device. The first polarizer is disposed on an optical path on one side of the sample carrying module. The second polarizer is disposed on the optical path on the other side of the sample carrying module.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: March 3, 2020
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
  • Patent number: 10495868
    Abstract: A microscope apparatus includes a sample carrying module, a light source module and a lens module. The sample carrying module includes an adhesive element and a body having a light-transmission region and a sample viewing surface. The adhesive element is detachably adhered to the body, and at least partially covers the light-transmission region, such that the adhesive element is disposed adjacent to the sample viewing surface. The light source module is detachably disposed at a side of the body, and includes a base and a light source. The base has an aperture, and the sample carrying module is detachably disposed at a side of the aperture. The light source is disposed in the base. The lens module includes at least one lens, which is detachably disposed at one side of the sample carrying module and substantially focuses at the sample viewing surface, and corresponds to the light source module.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: December 3, 2019
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
  • Patent number: 10495863
    Abstract: The present invention discloses a portable microscope device which can be installed on the smartphone capable of capturing image. By combing these devices, users can observe the detection sample and capture the image of the sample instantly without environment limitation. Moreover, during operation, the user can observe the whole image of the sample by substituting the microscope lens of different magnification ratio or by shifting the position of the sample.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: December 3, 2019
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Shu-Sheng Lin, Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang
  • Patent number: 10362706
    Abstract: Examples herein relate to server systems with hinge mechanisms. In one example, a server system includes a first enclosure and a second enclosure, the first and second enclosure each include a front end and a back end disposed opposite to each other, the front end having an opening. The server system further includes a hinge mechanism, the hinge mechanism connecting an upper edge of the back end of the first enclosure to an upper edge of the front end of the second enclosure. The first enclosure is adapted to rotate around the hinge mechanism.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: July 23, 2019
    Assignee: Hewlett Packard Enterprise Development LP
    Inventors: Geoffrey Sun, Chun-han Lin, Chang Yu Chen, Ku-Hsu Nien, Tse-Jen Sung
  • Patent number: 10354271
    Abstract: An electronic device and a play and interactive method for an electronic advertising are provided. The electronic device includes a touch module, a display, a static information presentation structure and a data processing device. The touch module has a touch area for providing position of a measured object in the touch area. The display has a display area set in the touch area. The touch area is composed of the display area and a non-display area. The static information presentation structure is disposed on the non-display area. The data processing device determines whether the measured object performs a operation in the display area or the non-display area according to the position of the measured object provided by the touch module. When the operation is located in the non-display area, the data processing device displays a corresponding data in the display area according to position of the operation.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: July 16, 2019
    Assignee: AOPEN INC.
    Inventors: Chang-Yu Chen, Huei-Ju Liao
  • Patent number: 10288869
    Abstract: A reflecting microscope module cooperating with an image capturing module includes a housing, a lens and a sample adhesive substance. The housing has a sample inspecting surface located on one side of the housing opposite to the image capturing module. The lens is disposed in the housing and the sample adhesive substance is detachably disposed on a bottom of the housing. The sample adhesive substance adjacently connected to the sample inspecting surface includes a substrate and a glue layer. The glue layer is integrally combined with the substrate to form one piece. A reflecting microscope device is also disclosed.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: May 14, 2019
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang, Shu-Sheng Lin
  • Patent number: 10281708
    Abstract: A microscope module, which is cooperated with an image capturing module, includes a housing, a convex lens and an illumination assembly. The housing has a sample inspecting surface located on one side of the housing, which is opposite to the image capturing module. The convex lens is disposed in the housing, and the shortest distance between the sample inspecting surface and the convex lens ranges from 0.1 mm to 3.0 mm. The illumination assembly has a light source and is located between the image capturing module and the convex lens. The light emitted from the light source enters the convex lens through an input surface of the convex lens, leaves the convex lens through an output surface of the convex lens, and then reaches the sample inspecting surface. A microscope device containing the microscope module is also disclosed.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: May 7, 2019
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Cheng-Ming Lin, Chang-Yu Chen, Shu-Sheng Lin, Tsun-Chao Chiang
  • Publication number: 20180310427
    Abstract: Examples herein relate to server systems with hinge mechanisms. In one example, a server system includes a first enclosure and a second enclosure, the first and second enclosure each include a front end and a back end disposed opposite to each other, the front end having an opening. The server system further includes a hinge mechanism, the hinge mechanism connecting an upper edge of the back end of the first enclosure to an upper edge of the front end of the second enclosure. The first enclosure is adapted to rotate around the hinge mechanism.
    Type: Application
    Filed: April 19, 2017
    Publication date: October 25, 2018
    Inventors: Geoffrey SUN, Chun-han LIN, Chang Yu CHEN, Ku-Hsu NIEN, Tse-Jen SUNG
  • Patent number: 9900558
    Abstract: A microscope module includes a light source assembly, a sampling assembly and a diffusing element. The light source assembly includes a light source and a light guide element. The light source is disposed close to the light incidence end of the light guide element. The sampling assembly includes a cover and a base. The cover and the base are combined to define a sample accommodating space, which is located at the light exit end of the light guide element. The diffusing element is disposed between the light source and the sample accommodating space. The light emitted from the light source passes through the diffusing element and then enters the sample accommodating space. A microscope device containing the microscope module is also disclosed.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: February 20, 2018
    Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.
    Inventors: Cheng-Ming Lin, Shu-Sheng Lin, Chang-Yu Chen, Tsun-Chao Chiang
  • Publication number: 20170344176
    Abstract: An electronic device and a play and interactive method for an electronic advertising are provided. The electronic device includes a touch module, a display, a static information presentation structure and a data processing device. The touch module has a touch area for providing position of a measured object in the touch area. The display has a display area set in the touch area. The touch area is composed of the display area and a non-display area. The static information presentation structure is disposed on the non-display area. The data processing device determines whether the measured object performs a operation in the display area or the non-display area according to the position of the measured object provided by the touch module. When the operation is located in the non-display area, the data processing device displays a corresponding data in the display area according to position of the operation.
    Type: Application
    Filed: October 6, 2016
    Publication date: November 30, 2017
    Applicant: AOPEN INC.
    Inventors: Chang-Yu Chen, Huei-Ju Liao
  • Publication number: 20170227757
    Abstract: A portable microscope apparatus operated with an image capture device includes a sample carrying module, a lens module, a first polarizer and a second polarizer. The sample carrying module includes a transparent carrier and a sample adhesive element including a substrate and a glue layer. The substrate has a concave portion and an extending portion. The concave portion is adjacently connected to the extending portion to form a first surface. The glue layer is at least partially disposed on the first surface and in an integrated form with the substrate. The lens module is detachably connected to the image capture device, and disposed between the sample carrying module and the image capture device. The first polarizer is disposed on an optical path on one side of the sample carrying module. The second polarizer is disposed on the optical path on the other side of the sample carrying module.
    Type: Application
    Filed: January 27, 2017
    Publication date: August 10, 2017
    Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN
  • Publication number: 20170227518
    Abstract: A sample detecting device is used in cooperation with an image capturing device. The sample detecting device includes a first assembly and a second assembly. The first assembly includes a light emitting unit and a light-permeable unit. The light-permeable unit is disposed at one side of the light emitting unit. The first assembly and the second assembly match and connect with each other to form a sample containing space. The second assembly includes a body and a convex lens. The body has a first cavity portion and a second cavity portion. The light-permeable unit is disposed in the first cavity portion, and the convex lens is disposed in the second cavity portion. The light emitted from the light emitting unit sequentially passes through the light-permeable unit and the convex lens and leaves the body.
    Type: Application
    Filed: January 20, 2017
    Publication date: August 10, 2017
    Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN
  • Publication number: 20170227758
    Abstract: A reflecting microscope module cooperating with an image capturing module includes a housing, a lens and a sample adhesive substance. The housing has a sample inspecting surface located on one side of the housing opposite to the image capturing module. The lens is disposed in the housing and the sample adhesive substance is detachably disposed on a bottom of the housing. The sample adhesive substance adjacently connected to the sample inspecting surface includes a substrate and a glue layer. The glue layer is integrally combined with the substrate to form one piece. A reflecting microscope device is also disclosed.
    Type: Application
    Filed: January 31, 2017
    Publication date: August 10, 2017
    Inventors: Cheng-Ming LIN, Chang-Yu CHEN, Tsun-Chao CHIANG, Shu-Sheng LIN