Abstract: A food safety detection device includes a xylem fiber substrate, which is configured with a sampling portion and a reaction portion. The reaction portion includes at least one chemical reagent. The sampling portion absorbs a test sample. The test sample moves on the xylem fiber substrate to the reaction portion and reacts with the chemical reagent. A manufacturing method for the food safety detection device is also disclosed. The food safety detection device is advantageous for easy operation, safety and rapid analysis.

Abstract: A method of releasing an antihypertensive agent on a plant fiber bundle is proposed. Firstly, the antihypertensive agent is fixed onto the plant fiber bundle. Then, the antihypertensive agent is fixed onto the plant fiber bundle and released in a buffer solution system. Next, fluorescence analysis of released antihypertensive agent is performed to evaluate the release efficiency of the antihypertensive agent.

Abstract: A three dimensional lignocellulosic detection device includes a first lignocellulosic substrate and a second lignocellulosic substrate. When the first lignocellulosic substrate is in contact with a liquid specimen through capillary effect, the sample is absorbed into the second lignocellulosic substrate through the first lignocellulosic substrate, reacts with the detecting reagent on the second lignocellulosic substrate and makes a detection test. The three dimensional lignocellulosic detection device of the present invention have inherent advantages of the lignocellulosic such as natural material, low cost, easy manipulation and capillary effect and results in a good preventive diagnostic platform. Also, users may achieve preventive disease diagnostics without spending additional time and/or money.

Abstract: The present invention provides a biomedical device comprising a porous hydrophilic substrate; a hydrophobic material; a fluid inlet; two or more test zones, wherein fluid vertically flows through the porous hydrophilic substrate and then distributes into the test zones. The present invention further provides a method for making a biomedical device.

Abstract: A biomedical testing sheet comprises: a substrate with calligraphy paper material, wherein the substrate comprises a wax pattern layer, which is a part of a surface of the substrate coated by a waxy material, and penetrated and diffused by the waxy material, and the wax pattern layer comprises one or more carrying units for carrying one or more droplets of liquids to be measured. The lotus effect substantially prevents diffusion of the liquids and reagents on the carrying units, and reduces the required amount of liquids to be measured and the amount of agent.

Abstract: A lignocellulosic detection device includes a lignocellulosic substrate and at least one detection reagent absorbed/coated to lignocellulosic tissue of the lignocellulosic substrate. A liquid specimen is in contact with the lignocellulosic substrate so as to be absorbed to the lignocellulosic tissue of the lignocellulosic substrate by capillary action and react with the detection reagent to achieve specimen detection. The lignocellulosic detection device of the present invention is provided with inherent advantages of the lignocellulosic substrate such as natural material, low cost, easy manipulation and capillary effect and results in a good preventive diagnosis platform. Also, users may achieve preventive disease diagnosis without spending additional time and/or money.

Abstract: A detection device applied for detecting body fluids includes a substrate and a plurality of anti-growth factor antibodies. The substrate includes at least one reaction portion. The reaction portion includes a fiber-based material. Anti-growth factor antibodies are disposed on the fiber-based material. The present invention further provides a detection strip and a detection system for detecting body fluids. The present invention is advantageous for easy operation, lower amount of reagents and rapid analysis.

Abstract: The disclosure provides low cost, portable three-dimensional devices for performing multiplexed assays. The devices comprise at least two substantially planar layers disposed in parallel planes, wherein one of the layers is movable relative to each other parallel to the planes to permit the establishment of fluid flow communication serially between the two layers.

Abstract: A novel sperm quality assessment device includes a main frame and a test pad. The test pad is encircled by the main frame and includes an exposed introductory portion. The test pad has greater hydrophilicity than the main frame, and includes an MTT reagent. Therefore, the activity pattern of the colored motile sperms can be used to estimate sperm quality, such as motility. The present device has the particular advantage of using paper to reduce manufacturing cost, and is also easy to use.

Abstract: A chromatography filter paper-based ELISA includes following steps: providing a chromatography filter paper plate provided with a plurality of independent hydrophilic regions defined by at least one hydrophobic region; immobilizing an antigen of a sample onto one of the hydrophilic regions of the chromatography filter paper plate; and detecting the antigen with an ELISA process, wherein an antibody used in the ELISA process is a monoclonal antibody. The present invention has advantages in lower amount of loaded sample, higher sensitivity and rapid analysis in comparison to conventional ELISA.

Abstract: A method is proposed for fabricating small-scale, curved, polymeric structures. Firstly, desired patterns are created from droplets of photocurable PDMS after using ink or wax to create the desired patterns on a flexible material such as papers or plastic films. The photocurable PDMS droplets are then activated by UV light to form a small-scale polymeric mold. Next, polymeric curved structures can be obtained at millimeter scale by casting and curing thermocurable PDMS on the mold.

Abstract: A method is proposed for fabricating small-scale, curved structures. Firstly, a calligraphy paper or filter paper is provided. Liquid-phase material droplets are applied to calligraphy paper or filter paper to form a desired pattern at a contact angle that can form convex curved small-scale structures.

Abstract: A biomedical diagnostic device includes a hydrophilic layer, hydrophobic layer, and at least one test pad. The hydrophilic layer includes an exposed introductory portion adapted to introduce a test fluid, and is stacked with the hydrophobic layer with multiple access holes. At least one test pad, each of which includes a distinguishing reaction medium, is disposed in the corresponding holes that extend to contact the hydrophilic layer. The relations within the device are as follows: hydrophilicity of any of the test pads>hydrophilicity of the hydrophilic layer>hydrophilicity of the hydrophobic layer.

Abstract: The disclosure provides low cost, portable three-dimensional devices for performing multiplexed assays. The devices comprise at least two substantially planar layers disposed in parallel planes, wherein one of the layers is movable relative to each other parallel to the planes to permit the establishment of fluid flow communication serially between the two layers.

Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.

Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.

Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.