Abstract: This invention relates to a composition comprising physically modified, partially pregelatinized starch, which is useful as a multi-functional excipient for solid dosage forms, a method of making such composition, and solid dosage forms prepared using the composition. Such composition is characterized by a predominance of particles having both birefringent and non-birefringent portions, a sedimentation volume of between 1.5 and 9 ml/g, and a cold water solubility of between 1 and 8%. This free-flowing starch may have an average particle size greater than 30 ?m, and a moisture content of between 5 and 12% by weight. The 500 mg placebo tablet prepared from such composition at 13 kN using a manual tablet press equipped with a 1.11 cm ( 7/16?) standard concave punches has a crushing strength of at least 160 Newtons, and a disintegration time of no more than 10 minutes.

Abstract: The present invention relates to a method of producing a film forming blend of different acyl gellan gums with starch having similar textural and functional properties compared to gelatin. Films prepared using such blends have a high modulus and excellent strength and elongation. The present invention also relates to soft capsules prepared using such blends or films, which have good sealability.

Abstract: The present invention relates to a blend of gelling and non-gelling starches with gellan gums and a plasticizer having similar textural and functional properties compared to gelatin. Films prepared using such blends have excellent strength and elongation. The blend can also be used to prepare capsules without heat. The present invention has superior capsule sealability when prepared from such blends or films.

Abstract: The present invention relates to a blend of gelling and non-gelling starches with gellan gums and a plasticizer having similar textural and functional properties compared to gelatin. Films prepared using such blends have excellent strength and elongation. The blend can also be used to prepare capsules without heat. The present invention has superior capsule sealability when prepared from such blends or films.

Abstract: This invention relates to a composition comprising physically modified, partially pregelatinized starch, which is useful as a multi-functional excipient for solid dosage forms, a method of making such composition, and solid dosage forms prepared using the composition. Such composition is characterized by a predominance of particles having both birefringent and non-birefringent portions, a sedimentation volume of between 1.5 and 9 ml/g, and a cold water solubility of between 1 and 8%. This free-flowing starch may have an average particle size greater than 30 ?m, and a moisture content of between 5 and 12% by weight. The 500 mg placebo tablet prepared from such composition at 13 kN using a manual tablet press equipped with a 1.11 cm ( 7/16?) standard concave punches has a crushing strength of at least 160 Newtons, and a disintegration time of no more than 10 minutes.

Abstract: The present invention relates to a method of producing a film forming blend of different acyl gellan gums with starch having similar textural and functional properties compared to gelatin. Films prepared using such blends have a high modulus and excellent strength and elongation. The present invention also relates to soft capsules prepared using such blends or films, which have good sealability.

Abstract: The invention relates to a cleaning composition effective for the removal of coagulant residue from molds or formers used for forming latex articles. The cleaning composition is an aqueous solution containing ethylene diaminetetraacetate (EDTA) ions. The composition can be used alone, or as part of a system with one or more water baths and one or more ETDA, detergent or base containing baths, for the cleaning of formers or molds.

Abstract: The present invention is directed to a dispersion of polymer particles in a dispersing medium. The polymer particles each contain an average of more than two living radicals that are not chemically protected. The present invention is also directed to a free radical precipitation process involving combining at least one monomer in at least one solvent; dispersing said monomer solvent mixture in a dispersing medium that is non-miscible with the first solvent, using a surfactant, stabilizer or mixture thereof; initiating polymerization with at least one free-radical generating agent and conversion, to produce polymer particles containing radicals trapped by precipitation by virtue of being above the lower critical solution temperature of the system; and removing the precipitating agent either during or after free-radical generation to form a dispersion polymer in the dispersing medium having living, trapped radicals.

Abstract: The present invention is directed to a release composition for molds and formers used in the production of natural and synthetic latex articles. The release coating contains a water-borne, high Tg polymer formed from at least one hydrophobic monomer and at least one hydrophilic monomer, where the Tg of the polymer is at least −10° C. One advantage of the release composition is that it is compatible with a coagulant solution used in the formation of latex gloves. Articles formed using the release coating have good anti-blocking properties.

Abstract: The present invention is directed to the use of a polymer coating composition having a dispersant, microbeads and a high Tg polymer with a Tg of greater than −10° C. for the inner coating on natural and synthetic rubber articles, particularly for latex gloves. The coating for rubber articles, provides an inner surface coating that reduces friction between the latex and the hand to allow convenient donning. They are deliverable from aqueous solution.

Abstract: The present invention is directed to the use of a polymer coating composition microbeads and a high Tg polymer with a Tg of greater than −10° C. for the inner coating on natural and synthetic rubber articles, particularly for latex gloves. The coating composition provides an inner surface coating that reduces friction between the latex and the hand to allow convenient donning. The coating composition is deliverable from an aqueous solution.

Abstract: The present invention is directed to a dispersion of polymer particles in a dispersing medium. The polymer particles each contain an average of more than two living radicals that are not chemically protected. The present invention is also directed to a free radical precipitation process involving combining at least one monomer in at least one solvent; dispersing said monomer solvent mixture in a dispersing medium that is non-miscible with the first solvent, using a surfactant, stabilizer or mixture thereof; initiating polymerization with at least one free-radical generating agent and conversion, to produce polymer particles containing radicals trapped by precipitation by virtue of being above the lower critical solution temperature of the system; and removing the precipitating agent either during or after free-radical generation to form a dispersion polymer in the dispersing medium having living, trapped radicals.

Abstract: The present invention is directed to a process for reducing the extractable protein content of a natural rubber latex article comprising the steps of immersing a former in a coagulant solution to coat the former, immersing said coagulant-coated former into a natural rubber latex to coat the former with said latex, allowing the latex on the former to dry to form a gel-like deposit, leaching the cured latex on the former in at least one aqueous solution, and removing the finished glove from the former. The process is especially useful when the leaching is done in a buffered solution, or a series of alternating buffer/water solutions. The process is also useful in reducing the level of extractable protein in a polymer coated natural latex glove. The process can reduce the level of extractable protein below 300 micrograms/gram and lower.

Abstract: The present invention is directed to a release composition for molds and formers used in the production of natural and synthetic latex articles. The release coating contains a water-borne, high Tg polymer formed from at least one hydrophobic monomer and at least one hydrophilic monomer, where the Tg of the polymer is at least −10° C. One advantage of the release composition is that it is compatible with a coagulant solution used in the formation of latex gloves.

Abstract: The present invention is directed to a release composition for molds and formers used in the production of natural and synthetic latex articles. The release coating contains a water-borne, high Tg polymer formed from at least one hydrophobic monomer and at least one hydrophilic monomer, where the Tg of the polymer is at least −10° C. One advantage of the release composition is that it is compatible with a coagulant solution used in the formation of latex gloves.

Abstract: Allylated amide compounds are formulated into curable compositions with a free radical curing agent, and optionally, one or more fillers, for use as adhesives in the manufacture of microelectronic devices.

Abstract: Underfill encapsulants are prepared from allylated amide compounds and a curing initiator.

Abstract: This invention relates to underfill encapsulant compositions prepared from allylated amide compounds to protect and reinforce the interconnections between an electronic component and a substrate in a microelectronic device.

Abstract: Allylated amide compounds are formulated into curable compositions with a free radical curing agent, and optionally, one or more fillers, for use as adhesives in the manufacture of microelectronic devices.

Abstract: A curable composition for use in the fabrication and assembly of circuit components and printed wire boards, which may be designed to be reworkable, comprises one or more mono- or polyfunctional maleimide compounds, or one or more mono- or polyfunctional vinyl compounds other than maleimide compounds, or a combination of maleimide and vinyl compounds, with a free-radical initiator or a photoinitiator, and optionally, one or more fillers. The circuit component is formed by applying the curable composition to the printed wire board and curing the composition in situ on the board.