Abstract: Apparatus and methods are described for ultrasound guided optoacoustic monitoring to provide diagnostic information for many clinical applications of blood oxygenation in blood vessels and in tissues including for early diagnosis and management of circulatory shock (including that induced by hemorrhage). In certain embodiments provided herein, methods and apparatus for optoacoustics for measurement of blood oxygenation in the innominate vein are provided. In certain embodiments provided herein, are methods and apparatus for articulating an angle between an ultrasound probe and subject body to identify an optimum position for an optoacoustic probe to measure blood oxygenation in a target blood vessel or tissue.

Abstract: A refrigeration unit includes a cabinet and a first evaporator assembly. The first evaporator assembly is operable between an uninstalled condition and an installed condition. In the uninstalled condition, the first evaporator assembly is not assembled with the cabinet. In the installed condition, the first evaporator assembly is assembled with the cabinet. The first evaporator assembly includes a first evaporator, a first suction line connected to the first evaporator at a first suction line joint, and a first capillary tube connected to the first evaporator at a first capillary tube joint. The first suction line joint and the first capillary tube joint of the first evaporator assembly are leak testable in the uninstalled condition of the first evaporator assembly.

Abstract: A secure start system for an autonomous vehicle can include a communications router comprising an input interface to receive a boot-loader to enable network communications with a backend system. The secure start system utilizes a tunnel key from the backend system to establish a private communications session with a backend data vault. The secure start system then retrieves a set of decryption keys from the backend data vault, via the private communications session, to decrypt a plurality of encrypted drives of the autonomous vehicle, which enables one or more functions of the autonomous vehicle.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.

Abstract: A RADAR antenna system and method are provided. In an implementation, the system includes a base and first and second antennas configured to transmit independent first and second antenna beams, respectively. The first and second antennas are each coupled to the base so as to provide a common rotational axis for the first and second antennas. An antenna position controller is configured to independently control first and second transmission positions associated with the first and second antennas, respectively. Two different antenna technologies can be used, for example one for providing communications capability and the other for providing tracking capability. Other implementations include four or more antennas configured to transmit beams at similar or different frequencies. Improvements in scan rate proportional to the number of antennas are achieved compared to that achievable with a single beam, without an increase in the rotation rate of the antenna system.

Abstract: The disclosed invention relates to an improved system and method for treatment of soft tissue, e.g., for treatment of a snoring condition. The system can include a laser source; a hand piece; and a device for directing radiation emitted by the laser source to a treatment area (e.g., an oral treatment area). In some cases, the handpiece can include an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam such that it is non-ablative, prior to its delivery to a treatment region. In various embodiments, the system includes a CO2 laser capable of performing treatment in a more efficient manner than conventional techniques.

Abstract: A manufacturing system includes a tape advancing through the manufacturing system and a station of the manufacturing system. The tape includes a first portion having grains of an inorganic material bound by an organic binder. The station of the manufacturing system receives the first portion of the tape and prepares the tape for sintering by chemically changing the organic binder and/or removing the organic binder from the first portion of the tape, leaving the grains of the inorganic material, to form a second portion of the tape and, at least in part, prepare the tape for sintering.

Abstract: A pre-pack assembly for use with an air gun and for use with a magazine that is removably insertable into the air gun, the pre-pack assembly includes a pre-pack that contains a gas canister, wherein inserting the pre-pack into the chamber of the magazine fluidly connects the gas canister with the magazine.

Abstract: A moveable micromachined member of a microelectromechanical system (MEMS) device includes an insulating layer disposed between first and second electrically conductive layers. First and second mechanical structures secure the moveable micromachined member to a substrate of the MEMS device and include respective first and second electrical interconnect layers coupled in series, with the first electrically conductive layer of the moveable micromachined member and each other, between first and second electrical terminals to enable conduction of a first joule-heating current from the first electrical terminal to the second electrical terminal through the first electrically conductive layer of the moveable micromachined member.

Abstract: By way of example, there is disclosed a method of a device communicating messages in a vehicle, such as an autonomous vehicle (AV), including: participating in mutual authentication with a key server located on the vehicle; receiving from the key server a cryptographic key; using the cryptographic key for symmetric cryptography, comprising signing messages sent to or verifying messages received from another device of the vehicle; and clearing the cryptographic key at reboot.

Abstract: A bottle (20) comprising an open-topped outer container (21) comprising a resilient body (22) for holding a water, an inner container comprising a flexible pouch (28) for holding a gel, a closure (24) adapted to fix to the top of the outer container thereby forming an enclosure for containing the water, a fixing (38,42) configured to allow the inner container to be suspended from the closure, an outlet that is in fluid communication with both the outer container and the inner container thereby allowing the outlet to dispense the water and the gel, a switch mechanism (41) including a switch moveable to select between placing the outlet in fluid communication with the outer container and placing the outlet in fluid communication with the inner container, and an air inlet and a one-way valve configured to allow air to flow into the outer container.

Abstract: An improved in-vehicle infotainment (IVI) system and methodology facilitating the display, computation, receipt and transmission of enhanced data elements and data files. System and methodology comprising an improved IVI system with an enhanced series of software and firmware capable of communicating with external data servers, processing enhanced protocols, transmitting data elements in report form with data attachments, and displaying the received enhanced data elements onto callout icons overlaid onto a GPS navigation interface. Additional system and methods include protocols for external servers to receive, encode, decode, compress, decompress, store, compute and transmit emergency reports and aggregate data files.

Abstract: In a tracking device system, a networked smart device is enabled to cause execution of an executable function if a trigger condition of a conditional rule is satisfied. The conditional rules are customizable on a user interface of the smart device. The trigger condition may be any information received in a signal from a tracking device, for example, sensor data, location, a time, a date, a button press, a proximity, and more generally a trigger condition can be any condition that has a truth value by which an IF/THEN conditional rule can be evaluated and either is satisfied or is not. Executable functions for use in conditional rules may be selected from functions of a smart device, but also may include any function of a remote machine, network or system. Bluetooth radiotag devices may also include a cellular radio modem for global networking. Network systems may include software for tracking groups of radiotags and for autoprovisioning location and tracking services.

Abstract: Compositions include highly concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).

Abstract: A bottom garment including a front panel, a back panel, and a garment lining. The front panel formed of a first fabric and the garment lining formed of a second fabric. The garment lining attached to an inside surface of the front panel and an inside surface of the back panel. The garment lining attached above a crotch point of the garment such that the garment lining is less restrictive than the front panel.

Abstract: Systems, methods, and devices of a voice-directed inspection system that supports multiple inspectors in the inspection of business assets are described. Inspection plans for large and complex business assets can involve several steps. It is advantageous to split large inspection plans into non-overlapping sections to allow multiple inspectors to perform concurrent inspections. Such sectionalizing is also useful in training new inspectors.

Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).

Abstract: By way of example, there is disclosed a method of a device communicating messages in a vehicle, such as an autonomous vehicle (AV), including: participating in mutual authentication with a key server located on the vehicle; receiving from the key server a cryptographic key; using the cryptographic key for symmetric cryptography, comprising signing messages sent to or verifying messages received from another device of the vehicle; and clearing the cryptographic key at reboot.

Abstract: Systems and methods are provided for managing a device in a vehicle, comprising: receiving a device registration request for the device; evaluating a list that includes a plurality of unique identifiers associated with a plurality of certificates; determining whether a particular unique identifier associated with a particular certificate is valid based on a length of time for the particular certificate; and communicating a signed version of the particular certificate to authorize a session for the device.