Patents by Inventor Charles A. Richardson

Charles A. Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for preparing synthetic repetitive DNA
    Patent number: 5641648
    Abstract: Methods are provided for the production of large polypeptides containing repeating sequences of amino acids utilizing biochemical techniques, specifically DNA sequences coding for the expression of the large polypeptides. Systems utilizing exogenous transcriptional and translational regions to control the production of the large polypeptides are also provided.
    Type: Grant
    Filed: December 29, 1993
    Date of Patent: June 24, 1997
    Assignee: Protein Polymer Technologies, Inc.
    Inventors: Franco A. Ferrari, Joseph Cappello, Charles Richardson
  • DNA polymerase having modified nucleotide binding site for DNA sequencing
    Patent number: 5614365
    Abstract: Modified gene encoding a modified DNA polymerase wherein the modified polymerase incorporates dideoxynucleotides at least 20-fold better compared to the corresponding deoxynucleotides as compared with the corresponding naturally-occurring DNA polymerase.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: March 25, 1997
    Assignee: President & Fellow of Harvard College
    Inventors: Stanley Tabor, Charles Richardson
  • Method and apparatus for reducing ambient noise effects in electronic monitoring instruments
    Patent number: 5555882
    Abstract: The present invention provides a method and apparatus for adapting to noise sources affecting a pulse oximeter. Various available frequencies are evaluated to determine their respective noise levels and one is selected to act as the operating demultiplexer frequency. During normal operation of the pulse oximeter, the various available demultiplexer frequencies are periodically scanned to determine which has the lowest associated noise. The noise level associated with the operating frequency is used to determine the signal-to-noise ratio of the pulse oximeter signals and thereby qualify certain signals from the pulse oximeter. Those pulses associated with a signal-to-noise ratio below a predetermined threshold are rejected and excluded from use in calculating blood oxygen saturation.
    Type: Grant
    Filed: August 24, 1994
    Date of Patent: September 17, 1996
    Assignee: Nellcor Incorporated
    Inventors: Charles A. Richardson, Michael Bernstein, Jerry K. Okikawa, Terrence R. Bennett
  • Method for reducing ambient noise effects in electronic monitoring instruments
    Patent number: 5368224
    Abstract: The present invention provides a method and apparatus for adapting to noise sources affecting a pulse oximeter. Various available frequencies are evaluated to determine their respective noise levels and one is selected to act as the operating demultiplexer frequency. During normal operation of the pulse oximeter, the various available demultiplexer frequencies are periodically scanned to determine which has the lowest associated noise. The noise level associated with the operating frequency is used to determine the signal-to-noise ratio of the pulse oximeter signals and thereby qualify certain signals from the pulse oximeter. Those pulses associated with a signal-to-noise ratio below a predetermined threshold are rejected and excluded from use in calculating blood oxygen saturation.
    Type: Grant
    Filed: October 23, 1992
    Date of Patent: November 29, 1994
    Assignee: Nellcor Incorporated
    Inventors: Charles A. Richardson, Michael Bernstein, Jerry K. Okikawa, Terrence R. Bennett
  • Construction of synthetic DNA and its use in large polypeptide synthesis
    Patent number: 5243038
    Abstract: Methods are provided for the production of large polypeptides containing repeating sequences of amino acids utilizing biochemical techniques, specifically DNA sequences coding for the expression of the large polypeptides. Systems utilizing exogenous transcriptional and translational regions to control the production of the large polypeptides are also provided.
    Type: Grant
    Filed: October 29, 1987
    Date of Patent: September 7, 1993
    Assignee: Protein Polymer Technologies, Inc.
    Inventors: Franco A. Ferrari, Charles Richardson, James Chambers, Stuart C. Causey, Thomas J. Pollock, Joseph Capello, John W. Crissman
  • Ultrasonic inspection apparatus
    Patent number: 3958451
    Abstract: An ultrasonic inspection method and apparatus for inspecting test objects such as pipeline girth welds are disclosed. Ultrasonic transducers are carried by a track circumferentially mounted around the pipeline. The transducers are mounted in a hollow, open-ended housing and a flexible seal fixed to the housing retains coupling liquid between the transducers and the pipeline to permit the propogation of waves between the transducers and the weld. An adjustable pressure regulating device maintains substantially constant liquid pressure within the housing in order to minimize the loss of coupling liquid and yet insure adequate coupling between the transducers and the weld.
    Type: Grant
    Filed: December 12, 1973
    Date of Patent: May 25, 1976
    Assignee: Inspection Technology Development, Inc.
    Inventor: Anthony Charles Richardson