Patents by Inventor Charles Hart

Charles Hart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190132254
    Abstract: Techniques are disclosed relating to creating and managing an information flow within a multi-layer computer network. In various embodiments, a computer system in a first layer within a multi-layer computer network, maintains state information defining an information flow within the multi-layer computer network. In various embodiments, the computer system assigns a particular action (that is included in the information flow) to be performed at a second, different layer of the multi-layer computer network. In various embodiments, the computer system generates program instructions to perform the particular action. The program instructions may be generated using device information accessible to the computer system and indicative of characteristics of a computer system within the second layer. In various embodiments, the computer system in the first layer causes the program instructions to be sent to the computer system in the second layer to perform the particular action as part of the defined information flow.
    Type: Application
    Filed: January 31, 2018
    Publication date: May 2, 2019
    Inventor: Charles Hart Isaacs
  • Publication number: 20190060275
    Abstract: Administration of a hypoxia activated prodrug in combination with an antiangiogenic agent is useful for treating cancer.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 28, 2019
    Applicant: Molecular Templates, Inc.
    Inventors: Charles Hart, John Curd, Stewart Kroll, Jessica Sun
  • Patent number: 9992242
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: June 5, 2018
    Assignee: salesforce.com, Inc.
    Inventor: Charles Hart Isaacs
  • Publication number: 20170054772
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Application
    Filed: August 24, 2016
    Publication date: February 23, 2017
    Inventor: Charles Hart Isaacs
  • Patent number: 9474519
    Abstract: The application relates to a hand access laparoscopy device having a gelcap, a retainer, a sleeve and a retention ring. The gelcap includes gel that is bonded to a cap. The cap includes an inner cylindrical wall to which the gel in bonded, thereby providing a sealing area between the device and the wound in a body wall. By securing the gel to the inner cylindrical wall, the thickness of the gel and corresponding cap is minimized along with the overall footprint of the device. With the gel thickness reduced and able to be substantially flush, the “doming” phenomenon produced by insufflation of a patient's abdomen is reduced.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: October 25, 2016
    Assignee: Applied Medical Resources Corporation
    Inventors: John Brustad, Jeremy Albrecht, Nabil Hilal, Gary Johnson, Charles Hart
  • Publication number: 20160296538
    Abstract: Cancer patients likely to respond to HAP treatment exhibit tumor tissues with high levels of hypoxia, which can be measured using PET imaging with [18F]-HX4.
    Type: Application
    Filed: April 9, 2014
    Publication date: October 13, 2016
    Applicant: THRESHOLD PHARMACEUTICALS, INC.
    Inventors: Charles Hart, Harold E. Selick, Jessica Sun
  • Patent number: 9444857
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: September 13, 2016
    Assignee: salesforce.com, inc.
    Inventor: Charles Hart Isaacs
  • Publication number: 20160155152
    Abstract: The technology disclosed relates to connecting a user's location via a location mediation server with indications of interest in products and product groups and in real time. An application executing on a user's mobile computing device supplies a location. The location mediation server works with the application, using various allocations of effort, to match current locations to sales environments that set the product(s) of interest and, in some implementations, to product exemplars outside sales environments.
    Type: Application
    Filed: January 15, 2016
    Publication date: June 2, 2016
    Applicant: salesforce.com, inc.
    Inventor: Charles Hart ISAACS
  • Publication number: 20160065632
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Application
    Filed: November 10, 2015
    Publication date: March 3, 2016
    Inventor: Charles Hart Isaacs
  • Patent number: 9254299
    Abstract: Cancer can be treated by administration of TH-302 in combination with a Chk1 inhibitor.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: February 9, 2016
    Assignee: Threshold Pharmaceuticals, Inc.
    Inventors: Charles Hart, Fanying Meng, Jessica Sun
  • Patent number: 9185342
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 10, 2015
    Assignee: salesforce.com, inc.
    Inventor: Charles Hart Isaacs
  • Publication number: 20150316908
    Abstract: A sensor system includes a sensor module disposed in a compartment. The sensor module includes first and second sensors, a first processor, and a first transceiver. The second sensor is separated from the first sensor in the compartment. The first processor is configured to monitor the first and second sensors. The first transceiver is configured to transmit sensor data from the first processor to a location remote from said compartment.
    Type: Application
    Filed: November 14, 2011
    Publication date: November 5, 2015
    Applicant: Mount Everest Technologies, LLC
    Inventors: Theodore Eller, Charles Hart, William Pfarr, Jimmie H. Spraker
  • Publication number: 20150209076
    Abstract: The application relates to a hand access laparoscopy device having a gelcap, a retainer, a sleeve and a retention ring. The gelcap includes gel that is bonded to a cap. The cap includes an inner cylindrical wall to which the gel in bonded, thereby providing a sealing area between the device and the wound in a body wall. By securing the gel to the inner cylindrical wall, the thickness of the gel and corresponding cap is minimized along with the overall footprint of the device. With the gel thickness reduced and able to be substantially flush, the “doming” phenomenon produced by insufflation of a patient's abdomen is reduced.
    Type: Application
    Filed: April 8, 2015
    Publication date: July 30, 2015
    Applicant: Applied Medical Resources Corporation
    Inventors: John Brustad, Jeremy Albrecht, Nabil Hilal, Gary Johnson, Charles Hart
  • Publication number: 20150005263
    Abstract: Cancer can be treated by administration of TH-302 in combination with a Chk1 inhibitor.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 1, 2015
    Inventors: Charles Hart, Fanying Meng, Jessica Sun
  • Publication number: 20150005262
    Abstract: Cancer is treated by administration of a hypoxia activated prodrug in combination with an mTOR inhibitor.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 1, 2015
    Inventors: Charles Hart, Jessica Sun, Fanying Meng
  • Publication number: 20150005264
    Abstract: CA-IX levels are predictive of the probability that a cancer patient will respond favorably to cancer therapy involving administration of a hypoxia-activated prodrug. In a first aspect, the present invention provides a method for treating cancer comprising the steps of measuring CA-IX levels in a sample isolated from the patient, and administering a hypoxia-activated prodrug only if the CA-IX level measured is equal to or greater than about 30 pg/mL (e.g. 28.8 pg/mL) CA-IX protein in a serum sample, as may be measured, for example or without limitation, using an ELISA. In one embodiment, a HAP is administered if the measured CA-IX level is equal to or greater than about 75 pg/mL (e.g. 77.1 pg/mL) protein in a serum sample. Thus, in one embodiment, the CA-IX level is measured based on the amount of CA-IX protein in a serum sample.
    Type: Application
    Filed: January 30, 2013
    Publication date: January 1, 2015
    Inventor: Charles Hart
  • Publication number: 20140098176
    Abstract: In accordance with disclosed embodiments, there are provided methods, systems, and apparatuses for implementing instant social image cobrowsing through the cloud, including, for example, means for loading an application at the client device, the application displaying a graphical interface at the client device; receiving input at the graphical interface of the client device to initiate an instant share session; generating an action at the client device to request an instant share session; communicating the action from the client device to a remote host organization via a public Internet; receiving, at the client device, a pointer to a dynamically created co-browse site at the host organization responsive to communicating the action from the client device to the remote host organization; following the pointer to the dynamically created co-browse site at the host organization communicably linking the client device with the host organization; and exchanging a video telephony stream between the client device and
    Type: Application
    Filed: September 27, 2013
    Publication date: April 10, 2014
    Applicant: salesforce.com, Inc.
    Inventor: Charles Hart Isaacs
  • Patent number: 8276516
    Abstract: An apparatus for detonating an initiation charge that is formed of a secondary explosive, such as triaminotrinitrobenzene (TATB). The apparatus includes an exploding foil initiator, which can have a relatively small flyer that is suited to initiate a detonation event in the initiation charge.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: October 2, 2012
    Assignee: Reynolds Systems, Inc.
    Inventors: Christopher J. Nance, John Yelverton, Charles Hart, Michael Meadows
  • Publication number: 20100215511
    Abstract: A system and method for turning on and off a bilge pump whereby bilge water level is detected using level sensors and bilge pumps are turned on and off based on the detected water level. The system further incorporates an automatic transmission outside the watercraft to alert of the water level in the bilge. The system is controllable from within the watercraft and remotely controllable through wireless transmission.
    Type: Application
    Filed: February 26, 2010
    Publication date: August 26, 2010
    Inventors: Theodore Eller, Charles Hart, William Pfarr, Jim Spraker
  • Publication number: 20090077584
    Abstract: Methods, systems, and products are disclosed for sharing presence information. Presence notifications are received from users, and the presence notifications describe content items currently being received by the users. A popularity of one or more of the content items being received by the users is determined. An electronic programming guide is provided that includes information regarding the one or more of the content items and the determined popularity associated with the one or more of the content items.
    Type: Application
    Filed: September 17, 2007
    Publication date: March 19, 2009
    Inventors: Jay Oliver Glasgow, Brett D. Johnson, Laurence Siegel, Charles Hart