Patents by Inventor Charles Keller

Charles Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250064712
    Abstract: An action of amplifying expression of an epidermal barrier function-related gene by a diacylglycerol polyethylene glycol adduct is utilized. A method for amplifying expression of an epidermal barrier function-related gene is provided. The method comprises applying a diacylglycerol PEG adduct, wherein the diacylglycerol PEG adduct is at least one of a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
    Type: Application
    Filed: June 14, 2024
    Publication date: February 27, 2025
    Inventors: Tatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
  • Publication number: 20250051703
    Abstract: An egg opener for a predetermined number of eggs contains a frame and a sliding blade holder which simplifies and speeds up embryo transfer to multi-well plates. A method for preparing an ex ovo tumor xenograft contains the steps of: preparing an ex ovo CAM and adding a cell-infused media to the CAM, wherein the cell-infused media comprises tumor cells to form an ex ovo tumor xenograft. An assay for testing a therapeutic compound contains the steps of providing an ex ovo tumor xenograft as described herein, and adding a therapeutic compound to the CAM, preferably via a therapeutic compound infused in a delivery media such as, for example, an osmotic bead. A method herein can test a therapeutic compound via an ex ovo quail egg xenograft assay, and methods and drugs herein may treat Ewing sarcoma, rhabdomyosarcoma and hepatoblastoma.
    Type: Application
    Filed: October 7, 2022
    Publication date: February 13, 2025
    Inventors: Charles KELLER, III, Samuel Val RASMUSSEN
  • Publication number: 20250049693
    Abstract: An action of amplifying expression of transporter-related genes in epidermal cells by a diacylglycerol PEG adduct is utilized. A method for amplifying expression of transporter-related genes in epidermal cells is provided. The method comprises applying a diacylglycerol PEG adduct, wherein the diacylglycerol PEG adduct is at least one of a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
    Type: Application
    Filed: June 14, 2024
    Publication date: February 13, 2025
    Inventors: Tatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
  • Patent number: 11642369
    Abstract: To enhance expression of an antioxidant-related substance in an epidermis by using a diacylglycerol PEG adduct, a method for enhancing expression of an antioxidant-related substance in an epidermis is provided which includes applying a diacylglycerol PEG adduct to the epidermis as an active ingredient. The antioxidant-related substance is an oxidative stress response gene, an antioxidant enzyme, or an antioxidant protein. The diacylglycerol PEG adduct is selected from the group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
    Type: Grant
    Filed: August 10, 2021
    Date of Patent: May 9, 2023
    Assignee: J-Network, Inc.
    Inventors: Tatsuro Miyoshi, Brian Charles Keller, Akira Kodama
  • Publication number: 20220160755
    Abstract: To enhance expression of an antioxidant-related substance in an epidermis by using a diacylglycerol PEG adduct, a method for enhancing expression of an antioxidant-related substance in an epidermis is provided which includes applying a diacylglycerol PEG adduct to the epidermis as an active ingredient. The antioxidant-related substance is an oxidative stress response gene, an antioxidant enzyme, or an antioxidant protein. The diacylglycerol PEG adduct is selected from the group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
    Type: Application
    Filed: August 10, 2021
    Publication date: May 26, 2022
    Inventors: Tatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
  • Publication number: 20220062429
    Abstract: To enhance expression of a moisturizing-related substance in an epidermis by using a diacylglycerol PEG adduct, a method for enhancing expression of a moisturizing-related substance in an epidermis is provided which includes applying a diacylglycerol PEG adduct to the epidermis as an active ingredient. The moisturizing-related substance is filaggrin, profilaggrin, and/or caspase-14. The diacylglycerol PEG adduct is selected from a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GD012).
    Type: Application
    Filed: August 10, 2021
    Publication date: March 3, 2022
    Inventors: Tatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
  • Patent number: 11000477
    Abstract: To provide a preparing method for a charged niosome which is formed of a lipid containing a diacylglycerol PEG adduct and which is capable of being excellently impregnated into the skin and stored in the skin.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: May 11, 2021
    Assignee: J-NETWORK, INC.
    Inventors: Tatsuro Miyoshi, Brian Charles Keller, Akira Kodama
  • Patent number: 10817516
    Abstract: A set of user interfaces is provided to an administrator of a website. The user interfaces enable the administrator to configure search functionality of the website to present different types of search results differently. For instance, the administrator can use the user interfaces to configure the search functionality to present different properties for search results belonging to different result types.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: October 27, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Charles Keller Smith, Jonathan Thomas Campbell, Zhenguang Chen, Arun Keller Krishnamoorthy, Boxin Li, Charles Reeves Little, II, Viktoriya Taranov, Brian William Timm, Andrew Joseph Violino
  • Publication number: 20190091153
    Abstract: To provide a preparing method for a charged niosome which is formed of a lipid containing a diacylglycerol PEG adduct and which is capable of being excellently impregnated into the skin and stored in the skin.
    Type: Application
    Filed: July 20, 2018
    Publication date: March 28, 2019
    Applicant: J-Network, Inc.
    Inventors: Tatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
  • Patent number: 10210260
    Abstract: A client device presents a resource to a user. In order to present the resource, the client device generates and renders one or more presentation strings. The client device generates a presentation string by identifying a template module that corresponds to an content resource object in a dataset downloaded by the client device. The client device then performs a template execution operation on the content resource object. The template module corresponding to the content resource object specifies the template execution operation.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: February 19, 2019
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Jonathan Thomas Campbell, Zhenguang Chen, Anthony Lawrence Jackson, Ping Jiang, Arun Krishnamoorthy, Boxin Li, Charles Reeves Little, II, Charles Keller Smith, Brian William Timm, Andrew Joseph Violino, Kerem Yuceturk
  • Patent number: 10194600
    Abstract: This invention relates to agriculture, hydroponics, the art of growing plants indoors. True hydroponics requires living plants to grow directly in water and water only. This system allows for vegetation to be hung over water and is comprised of a system of collars that wrap around the stem or stalk of living plants to secure them within a system of support cuffs.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: February 5, 2019
    Inventor: Robert Charles Keller, Sr.
  • Publication number: 20170228465
    Abstract: A set of user interfaces is provided to an administrator of a website. The user interfaces enable the administrator to configure search functionality of the website to present different types of search results differently. For instance, the administrator can use the user interfaces to configure the search functionality to present different properties for search results belonging to different result types.
    Type: Application
    Filed: April 27, 2017
    Publication date: August 10, 2017
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Charles Keller Smith, Jonathan Thomas Campbell, Zhenguang Chen, Arun Keller Krishnamoorthy, Boxin Li, Charles Reeves Little, II, Viktoriya Taranov, Brian William Timm, Andrew Joseph Violino
  • Patent number: 9652545
    Abstract: A set of user interfaces is provided to an administrator of a website. The user interfaces enable the administrator to configure search functionality of the website to present different types of search results differently. For instance, the administrator can use the user interfaces to configure the search functionality to present different properties for search results belonging to different result types.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: May 16, 2017
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Charles Keller Smith, Jonathan Thomas Campbell, Zhenguang Chen, Arun Krishnamoorthy, Boxin Li, Charles Reeves Little, II, Viktoriya Taranov, Brian William Timm, Andrew Joseph Violino
  • Publication number: 20150379145
    Abstract: A set of user interfaces is provided to an administrator of a website. The user interfaces enable the administrator to configure search functionality of the website to present different types of search results differently. For instance, the administrator can use the user interfaces to configure the search functionality to present different properties for search results belonging to different result types.
    Type: Application
    Filed: September 3, 2015
    Publication date: December 31, 2015
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Charles Keller Smith, Jonathan Thomas Campbell, Zhenguang Chen, Arun Keller Krishnamoorthy, Boxin Li, Charles Reeves Little, Viktoriya Taranov, Brian William Timm, Andrew Joseph Violino
  • Publication number: 20150269307
    Abstract: Disclosed is a system and method for targeted therapy designs which model a cancer pathway for predicting the effectiveness of targeted anti-cancer drugs. The disclosed system and method includes utilization of a computer processor allowing for the selection of a set of drugs from available drugs using approximation algorithms utilizing cell viability data associated with a testable culture of a patient's tumor for generating a probabilistic target inhibition map (PTIM) from viability data for considering the selection of a set of drugs from available drugs, and further supports a wide variety of scenarios for personalized cancer therapy, related products and services.
    Type: Application
    Filed: March 18, 2015
    Publication date: September 24, 2015
    Inventors: Ranadip Pal, Charles Keller, III, Noah E. Berlow, Bernard Seguin
  • Patent number: 9135358
    Abstract: A set of user interfaces is provided to an administrator of a website. The user interfaces enable the administrator to configure search functionality of the website to present different types of search results differently. For instance, the administrator can use the user interfaces to configure the search functionality to present different properties for search results belonging to different result types.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: September 15, 2015
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Jonathan Thomas Campbell, Zhenguang Chen, Arun Krishnamoorthy, Boxin Li, Charles Reeves Little, II, Charles Keller Smith, Viktoriya Taranov, Brian William Timm, Andrew Joseph Violino
  • Patent number: 8828355
    Abstract: Disclosed are compositions and methods for imaging in animals.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: September 9, 2014
    Assignee: University of Utah Research Foundation
    Inventors: Charles Keller, Patrick J. Hawkes
  • Publication number: 20140201231
    Abstract: A social collaboration search tool provides a mechanism for collaborators within an organization to search for and retrieve conversations that include social knowledge interactions. The social collaboration search tool may also provide additional social information to the searcher. The social knowledge interactions search tool can provide a mechanism by which these interactions are indexed and surfaced in a first class search vertical with specialized display formats that may enable the searcher to efficiently retrieve and use the most important or relevant information.
    Type: Application
    Filed: January 11, 2013
    Publication date: July 17, 2014
    Applicant: Microsoft Corporation
    Inventors: Charles Keller Smith, Duane Stanley Bolick, JR., Andrew Joseph Violino, Glen Howard Anderson, Yoo Mi Lee
  • Patent number: 8553836
    Abstract: Disclosed is a process of producing a microCT image of a stained specimen, wherein said specimen is a non-human organ, said process comprising: incubating a specimen in a first staining composition, said first staining composition comprising a first staining agent, to produce a stained specimen; submerging said stained specimen in a liquid with an electron density lower than that of said stained specimen; and placing said stained specimen in a specimen holder and scanning said stained specimen in an X-ray computed tomography scanner to produce said microCT image of said stained specimen.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: October 8, 2013
    Assignee: The Board of Regents, The University of Texas System
    Inventors: Charles Keller, Ali N. Bahadur
  • Publication number: 20130067338
    Abstract: A request for a page in a site can be received. The page can include a dynamic navigation region. The dynamic navigation region can be automatically updated based on usage of the site by multiple user profiles. The updating can include querying multiple sources of navigation item data and compiling a record of dynamic navigation items to be displayed in the dynamic navigation region. The page can be generated with the dynamic navigation region, and the page can be returned in response to the page request. Also, a request to pin a navigation item from the dynamic navigation region to the static navigation region can be received. In response to the request to pin, the pinned navigation item can be added to the static navigation region, and the page can be returned with the pinned navigation item added to the static navigation region.
    Type: Application
    Filed: September 14, 2011
    Publication date: March 14, 2013
    Applicant: MICROSOFT CORPORATION
    Inventors: Jonathan F. Kern, Nathaniel Granor, Richard Eric Andeen, Charles Keller Smith, Ashok Kuppusamy