Patents by Inventor Charles Knowles

Charles Knowles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA strand resolution
    Patent number: 5948642
    Abstract: The invention provides DNA strand resolution polypeptides and DNA (RNA) encoding DNA strand resolution polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DNA strand resolution polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 2, 1997
    Date of Patent: September 7, 1999
    Assignee: Smithkline Beecham p.l.c.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • ribA
    Patent number: 5932701
    Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: August 3, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Michael Terence Black, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Anna Lisa Kosmatka, Richard Oakley Nicholas, Leslie Marie Palmer, Lisa Kathleen Shilling, Robert King Stodola, Richard Lloyd Warren
  • Polynucleotides encoding GTP cyclohydrolase II (ribA)
    Patent number: 5891672
    Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: April 6, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Min Wang, Judith M Ward, Richard Lloyd Warren, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, David Justin Charles Knowles, Michael Arthur Lonetto, Jeffrey Mooney, Michael Terence Black, Martin Karl Russell Burnham, Christine Debouck, Jason Craig Fedon, John Edward Hodgson, Deborah Dee Jaworski, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Yi Yi Zhong
  • gbpA
    Patent number: 5885805
    Abstract: The invention provides gbpA polypeptides and DNA (RNA) encoding gbpA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gbpA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 23, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Arthur Lonetto, Patrick Vernon Warren, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward
  • Ferrichrome transport ATP-binding protein
    Patent number: 5882891
    Abstract: The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Ferrichrome transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: March 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakly Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • yitJ
    Patent number: 5882897
    Abstract: The invention provides yitJ polypeptides and DNA (RNA) encoding yitJ polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yitJ polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 16, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham, p.l.c.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • PCR A
    Patent number: 5858718
    Abstract: The invention provides pcrA polypeptides and DNA (RNA) encoding pcrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pcrA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Robert King Stodola, David J. Holmes
  • Glucose kinase from streptococcus pneumoniae
    Patent number: 5840560
    Abstract: The invention provides Glucose Kinase polypeptides and DNA (RNA) encoding Glucose Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glucose Kinase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 24, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O. Nicholas, Robert King Stodola, Martin Karl Russel Burnham