Patents by Inventor Charles Mistretta

Charles Mistretta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090076369
    Abstract: A composite image is produced for use in HYPR processing a current image frame. The amount of a priori data used to form the composite is determined by the amount of subject motion. The current composite image may be spatially registered with the current image frame to offset subject motion before being used to form an updated composite image. Subject motion may be analyzed on a frame-by-frame basis, a region-by-region basis or a pixel-by-pixel basis to optimize the SNR of the updated composite image.
    Type: Application
    Filed: September 11, 2008
    Publication date: March 19, 2009
    Inventor: Charles A. Mistretta
  • Publication number: 20080219535
    Abstract: An image reconstruction method includes reconstructing a composite image of a subject using a conventional reconstruction method. The composite image employs the best information available regarding the subject of the scan and this information is used to constrain the reconstruction of a highly undersampled image frames or improve the SNR of image frames. A blurred and normalized weighting image is produced from image frame data, and this normalized weighting image is multiplied by the composite image.
    Type: Application
    Filed: February 15, 2008
    Publication date: September 11, 2008
    Inventors: Charles A. Mistretta, Julia Velikina, Kevin Michael Johnson
  • Patent number: 7408347
    Abstract: A series of image frames are acquired in which an MR parameter such as echo time (TE) is changed and the resulting image frames are employed to produce an MRS image of a metabolite. Scan time is reduced without sacrificing image quality by reconstructing a composite image from data acquired for a plurality of the image frames and using a highly constrained image reconstruction method with the composite image to produce each image frame.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: August 5, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Scott Reeder, John Perry, Oliver Wieben
  • Patent number: 7358730
    Abstract: Highly undersampled diffusion weighted image data sets are acquired for a plurality of different directions using a projection reconstruction pulse sequence. The acquired projection views are interleaved and are combined to form a more highly sampled data set that is used to reconstruct a composite image. A DWI image is reconstructed from each undersampled data set for each direction using a highly constrained backprojected method that employs the composite image. Diffusion tensor values are calculated from the DWI images.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: April 15, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Andrew L. Alexander
  • Patent number: 7333588
    Abstract: An x-ray computed tomography system uses a broad area x-ray emitter and detector to allow both in plane and out of plane x-ray projections not restrained to spiral or helical scans.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: February 19, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Thomas R. Mackie
  • Publication number: 20070167728
    Abstract: Acquisition of MR data during a fMRI study employs a hybrid PR pulse sequence to acquire projection views from which multi-slice image frames may be reconstructed that depict the BOLD response to an applied stimulus or performed task. Composite images are reconstructed at each slice using the combined interleaved projection views from all the acquired image frames. The composite images are used to reconstruct the highly undersampled image frames.
    Type: Application
    Filed: September 21, 2006
    Publication date: July 19, 2007
    Inventors: Charles Mistretta, Walter Block
  • Publication number: 20070167729
    Abstract: A series of image frames are acquired in which an MR parameter such as echo time (TE) is changed and the resulting image frames are employed to produce an MRS image of a metabolite. Scan time is reduced without sacrificing image quality by reconstructing a composite image from data acquired for a plurality of the image frames and using a highly constrained image reconstruction method with the composite image to produce each image frame.
    Type: Application
    Filed: September 21, 2006
    Publication date: July 19, 2007
    Inventors: Charles Mistretta, Scott Reeder, John Perry, Oliver Wieben
  • Publication number: 20070167707
    Abstract: Projection views of the moving heart and stationary background tissues are acquired and processed to provide corresponding moving tissue projection views. An average image is reconstructed in a conventional manner and a moving tissue image is reconstructed using a highly constrained backprojection method and a composite image formed from selected moving tissue projection views. The average image is then combined with the moving tissue image. The method is disclosed in a cardiac gated MRI scan.
    Type: Application
    Filed: September 7, 2006
    Publication date: July 19, 2007
    Inventors: Charles Mistretta, Julia Velikina, Oliver Wieben
  • Publication number: 20070156044
    Abstract: A series of velocity encoded MR image frames are acquired. To increase the temporal resolution of the acquired image frames radial projections are acquired and each image frame is highly undersampled. The radial projections for each velocity encoding direction are interleaved throughout the scan and a composite phase image is reconstructed from these and used to reconstruct a velocity image for each image frame in a highly constrained backprojection method.
    Type: Application
    Filed: September 28, 2006
    Publication date: July 5, 2007
    Inventors: Charles Mistretta, Julia Velikina, Kevin Johnson, Oliver Wieben
  • Publication number: 20070156045
    Abstract: Highly undersampled diffusion weighted image data sets are acquired for a plurality of different directions using a projection reconstruction pulse sequence. The acquired projection views are interleaved and are combined to form a more highly sampled data set that is used to reconstruct a composite image. A DWI image is reconstructed from each undersampled data set for each direction using a highly constrained backprojected method that employs the composite image. Diffusion tensor values are calculated from the DWI images.
    Type: Application
    Filed: September 21, 2006
    Publication date: July 5, 2007
    Inventors: Charles Mistretta, Andrew Alexander
  • Publication number: 20070106149
    Abstract: A cardiac gated acquisition of MR data during a breath-hold employs a hybrid PR pulse sequence to acquire projection views from which image frames may be reconstructed at a plurality of cardiac phases during each heartbeat. Composite images are reconstructed at each cardiac phase using interleaved projection views acquired during all the heartbeats. The composite images are used to reconstruct the highly undersampled image frames at the same cardiac phase using a highly constrained backprojection method.
    Type: Application
    Filed: September 21, 2006
    Publication date: May 10, 2007
    Inventor: Charles Mistretta
  • Patent number: 7209535
    Abstract: A generalized projection-slice theorem for divergent beam projections is disclosed. The theorem results in a method for processing the Fourier transform of the divergent beam projections at each view acquired by a CT system to the Fourier transform of the object function. Using this method, an inverse Fourier transform may be used to reconstruct tomographic images from the acquired divergent beam projections.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: April 24, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guang-Hong Chen, Charles A. Mistretta
  • Publication number: 20070038073
    Abstract: Two-dimensional or three-dimensional, time-resolved MR frame images are acquired during a dynamic study of a subject. A composite MR image is produced and this is used to reconstruct each image frame by weighting the backprojection of each projection view acquired for that image frame. The composite image may be reconstructed from views acquired separately, or it may be produced by combining views acquired during the course of the dynamic study. A number of different clinical applications of the method are described.
    Type: Application
    Filed: July 7, 2006
    Publication date: February 15, 2007
    Inventor: Charles Mistretta
  • Publication number: 20070009080
    Abstract: Two-dimensional or three-dimensional, time-resolved CT frame images are acquired during a dynamic study of a subject. A composite image is produced and this is used to reconstruct each CT frame image by weighting the backprojection of each projection view acquired for that image frame by the corresponding value in the composite image. This weighted backprojection enables artifact-free image frames to be produced with far fewer projection views of the subject. The composite image may be reconstructed from views acquired separately, or it may be produced by combining views acquired during the course of the dynamic study.
    Type: Application
    Filed: July 7, 2006
    Publication date: January 11, 2007
    Inventor: Charles Mistretta
  • Publication number: 20070010731
    Abstract: An image reconstruction method includes reconstructing a composite image of a subject using a conventional reconstruction method. The composite image employs the best information available regarding the subject of the scan and this information is used to constrain the reconstruction of highly undersampled image frames. An image frame is reconstructed using limited acquired data and image quality is improved using a priori information of the subject by weighting pixel values therein by values of corresponding pixels in the composite image.
    Type: Application
    Filed: July 7, 2006
    Publication date: January 11, 2007
    Inventor: Charles Mistretta
  • Patent number: 7049816
    Abstract: A phase contrast image is produced using a 3D projection reconstruction pulse sequence. A high velocity-to-noise image is produced by using a LOW VENC motion encoding gradient. Phase wrap errors caused by high velocity flow is corrected using phase information in a HIGH VENC image produced from highly undersampled data acquired during the same scan.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: May 23, 2006
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Kevin Michael Johnson, Tianliang Gu
  • Publication number: 20060066306
    Abstract: A phase contrast image is produced using a 3D projection reconstruction pulse sequence. A high velocity-to-noise image is produced by using a LOW VENC motion encoding gradient. Phase wrap errors caused by high velocity flow is corrected using phase information in a HIGH VENC image produced from highly undersampled data acquired during the same scan.
    Type: Application
    Filed: September 30, 2004
    Publication date: March 30, 2006
    Inventors: Charles Mistretta, Kevin Johnson, Tianliang Gu
  • Publication number: 20060020200
    Abstract: A helical scan is performed with a fan beam or cone beam CT system to acquire a first set of sinogram data sets. The subject is injected with a contrast agent and the identical helical scan is performed to acquire a second set of sinogram data sets. Corresponding projection views are subtracted in the two data sets and a number of different images are reconstructed from the difference data set. One image is a tomographic image produced using a filtered backprojection method and a second image is a topograph produced by selecting and displaying projection views acquired at the same view angle in successive sinogram data sets.
    Type: Application
    Filed: July 8, 2004
    Publication date: January 26, 2006
    Inventors: Joshua Medow, Charles Mistretta, Ranjini Tolakanahalli, Jiang Hsieh
  • Patent number: 6983182
    Abstract: A contrast enhanced dynamic study of a subject is performed with a CT system. A series of undersampled image data sets are acquired during the study with successive data sets acquired at interleaved projection angles. More fully sampled image data sets are formed by transforming the x-ray attenuation projection data to k-space and then sharing peripheral k-space data between undersampled k-space data sets. Artifacts due to undersampling are thus reduced without significantly affecting the time resolution of a series of reconstructed images.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: January 3, 2006
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Charles A. Mistretta
  • Publication number: 20050251010
    Abstract: An x-ray system for use with image-guided medical procedures is programmed to move in a first scan path to acquire cone beam attenuation data from which a three-dimensional digital subtraction angiogram of selected vasculature is reconstructed. The x-ray system is also programmed to move in a second scan path to acquire a series of tomosynthesis images during the inflow of a contrast agent into the selected vasculature. Parametric images are produced from information in the tomosynthesis images which indicate blood perfusion physiology of the tissues served by the vasculature.
    Type: Application
    Filed: May 10, 2004
    Publication date: November 10, 2005
    Inventors: Charles Mistretta, Howard Rowley, Michael Van Lysel, Guang-Hong Chen