Patents by Inventor Charles Mistretta

Charles Mistretta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6954067
    Abstract: A three dimensional projection reconstruction pulse sequence is employed to acquire velocity encoded NMR data from which an image indicative of spin motion is reconstructed. The velocity encoding is along all three axes and it may include acquisitions at more than one velocity encoding first moment M1. When more than one first moment M1 is acquired, a 1DFT along the velocity encoding axis is performed prior to reconstructing images from the acquired NMR data.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: October 11, 2005
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Charles A. Mistretta
  • Publication number: 20050123092
    Abstract: An x-ray computed tomography system uses a broad area x-ray emitter and detector to allow both in plane and out of plane x-ray projections not restrained to spiral or helical scans.
    Type: Application
    Filed: December 13, 2002
    Publication date: June 9, 2005
    Inventors: Charles Mistretta, Thomas Mackie
  • Publication number: 20050100126
    Abstract: A CT imaging system includes a two-dimensional detector array and an x-ray source that both revolve around the subject during a scan. The x-ray source produces a cone beam of x-rays and the focal point of this cone beam is electrically moved to different locations along the z-axis to increase the z-axis extent of the ROI that can be imaged without patient table movement. Different focal point scan patterns are described for a variety of different clinical applications.
    Type: Application
    Filed: April 19, 2004
    Publication date: May 12, 2005
    Inventors: Charles Mistretta, Sarah Patch, Rostyslav Boutchko, Jiang Hsieh
  • Publication number: 20050033159
    Abstract: A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Arterial and venous voxels are automatically identified in the images using either of two disclosed methods. The signals from identified arterial voxels are used to produce an arterial contrast enhancement reference curve that is used to segment arterial voxels by a correlation process. Venous voxels are segmented in the same manner using a calculated venous contrast enhancement reference curve.
    Type: Application
    Filed: March 16, 2001
    Publication date: February 10, 2005
    Inventors: Charles Mistretta, Yousef Tehrani, Timothy Carroll, Jiang Du
  • Publication number: 20040258194
    Abstract: A generalized projection-slice theorem for divergent beam projections is disclosed. The theorem results in a method for processing the Fourier transform of the divergent beam projections at each view acquired by a CT system to the Fourier transform of the object function. Using this method, an inverse Fourier transform may be used to reconstruct tomographic images from the acquired divergent beam projections.
    Type: Application
    Filed: June 4, 2004
    Publication date: December 23, 2004
    Inventors: Guang-Hong Chen, Charles A. Mistretta
  • Patent number: 6671536
    Abstract: A 3D projection reconstruction pulse sequence is employed to acquire CEMRA data as the subject is continuously moved through the field of view of the MRI system. The acquired k-space data is phase corrected to offset the table motion and the corrected data is used to reconstruct an image over a field of view that far exceeds the size of the MRI system field of view. In one embodiment the image is formed as a set of anatomic subregion images which are concatenated to form a single image and in another embodiment a series of images of each anatomic subregion are produced to depict the dynamic inflow of contrast agent.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: December 30, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Charles A. Mistretta
  • Patent number: 6630828
    Abstract: High resolution and high speed MR imaging is provided for imaged objects in which the brightness of the imaged objects dominates the surrounding tissues by using sparse angular sampling and projection acquisition techniques. Individual objects throughout a large field of view are imaged at a rate and resolution normally associated with small field of view techniques. For applications such as angiography, artifacts associated with sparse angular sampling are acceptable. Volume images are acquired by combining sparsely sampled projection in two dimensions with weighted Fourier Acquisition in the third dimension.
    Type: Grant
    Filed: January 10, 2001
    Date of Patent: October 7, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Dana C. Peters
  • Publication number: 20030135103
    Abstract: A three dimensional projection reconstruction pulse sequence is employed to acquire velocity encoded NMR data from which an image indicative of spin motion is reconstructed. The velocity encoding is along all three axes and it may include acquisitions at more than one velocity encoding first moment M1. When more than one first moment M1 is acquired, a 1DFT along the velocity encoding axis is performed prior to reconstructing images from the acquired NMR data.
    Type: Application
    Filed: November 8, 2002
    Publication date: July 17, 2003
    Inventor: Charles A. Mistretta
  • Patent number: 6556856
    Abstract: A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of low resolution NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Additional, high spatial resolution NMR image data is acquired in a subsequent steady-state phase of the examination. The low resolution NMR image is segmented and masked to depict only arteries, and the central k-space region of this data is combined with the peripheral k-space data portion of the high resolution NMR data to produce one or more images.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: April 29, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Thomas M. Grist, Yousef Mazahheri, Timothy J. Carroll, Jiang Du, Walter Block
  • Publication number: 20030060698
    Abstract: A 3D projection reconstruction pulse sequence is employed to acquire CEMRA data as the subject is continuously moved through the field of view of the MRI system. The acquired k-space data is phase corrected to offset the table motion and the corrected data is used to reconstruct an image over a field of view that far exceeds the size of the MRI system field of view. In one embodiment the image is formed as a set of anatomic subregion images which are concatenated to form a single image and in another embodiment a series of images of each anatomic subregion are produced to depict the dynamic inflow of contrast agent.
    Type: Application
    Filed: September 25, 2001
    Publication date: March 27, 2003
    Inventor: Charles A. Mistretta
  • Publication number: 20030013953
    Abstract: A contrast enhanced dynamic study of a subject is performed with a CT system. A series of undersampled image data sets are acquired during the study with successive data sets acquired at interleaved projection angles. More fully sampled image data sets are formed by transforming the x-ray attenuation projection data to k-space and then sharing peripheral k-space data between undersampled k-space data sets. Artifacts due to undersampling are thus reduced without significantly affecting the time resolution of a series of reconstructed images.
    Type: Application
    Filed: August 20, 2002
    Publication date: January 16, 2003
    Inventor: Charles A. Mistretta
  • Patent number: 6487435
    Abstract: A 3D projection reconstruction pulse sequence is employed to acquire CEMRA images. In one application of the invention an undersampled, high resolution abdominal CEMRA image is acquired in a single breathhold. In another application of the invention a series of undersampled image frames are acquired during a CEMRA dynamic study Each image is produced by combining peripheral k-space data from adjacent image frames with the central and peripheral k-space data of an acquired image frame.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: November 26, 2002
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Andrew V. Barger, Walter F. Block
  • Patent number: 6381486
    Abstract: A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of low resolution NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Additional, high resolution NMR image data is acquired in a subsequent steady-state phase of the examination from which a high resolution NMR image is reconstructed. Segmentation of arteries, veins and background in the high resolution image is performed using information in the low resolution NMR images.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: April 30, 2002
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Thomas M. Grist, Timothy J. Carroll, Yousef Mazaheri
  • Publication number: 20010027262
    Abstract: A 3D projection reconstruction pulse sequence is employed to acquire CEMRA images. In one application of the invention an undersampled, high resolution abdominal CEMRA image is acquired in a single breathhold. In another application of the invention a series of undersampled image frames are acquired during a CEMRA dynamic study Each image is produced by combining peripheral k-space data from adjacent image frames with the central and peripheral k-space data of an acquired image frame.
    Type: Application
    Filed: January 23, 2001
    Publication date: October 4, 2001
    Inventors: Charles A. Mistretta, Andrew V. Barger, Walter F. Block
  • Patent number: 6195579
    Abstract: A dynamic MRA study is performed using a 3D fast gradient recalled echo pulse sequence. A signal strength indicator for each acquired k-space data set is calculated and these indicator values are employed to produce a contrast curve. This contrast curve is used to select data for use in forming a CONTRAST k-space data set and a MASK k-space data set. The MASK is subtracted from the CONTRAST data set and the result is used to reconstruct an image.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: February 27, 2001
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Timothy J. Carroll, Charles A. Mistretta
  • Patent number: 6188922
    Abstract: A magnetic resonance angiogram (MRA) is acquired using a pulse sequence that samples k-space at a projection angle. The acquired NMR signal is sensitized to spin motion with a bipolar motion encoding gradient and the pulse sequence is repeated to sample k-space at a set of different projection angles. A phase image is reconstructed from the acquired NMR signals using a filtered backprojection technique. Additional sets of projections with different motion encoding directions are acquired at interleaved projection angles, and the reconstructed phase images are combined to provide a velocity image.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: February 13, 2001
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Andrew V. Barger
  • Patent number: 6044290
    Abstract: A dynamic MRA study of a subject is performed using a 3D echo-planar imaging pulse sequence. Four phase encoding views are acquired for each pulse repetition period (TR) and this enables higher resolution images to be acquired without a reduction of temporal frame rate or a loss of image CNR.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: March 28, 2000
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Karl K Vigen, Charles A Mistretta, Thomas M Grist, Frank R Korosec, Richard Frayne
  • Patent number: 5881728
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Artifacts caused by variations in signal strength as the contrast agent enters the region of interest are reduced by renormalizing the acquired data. 2D image frames are reconstructed using planes passing near the center of k-space to enable the operator to select which 3D data sets should be used to reconstruct diagnostic images.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: March 16, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Thomas M. Grist, Richard Frayne, Frank Korosec
  • Patent number: 5873825
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. A difference image is produced by subtracting a mask formed by central region k-space sampling from a selected image frame formed by central region and peripheral regions k-space sampling.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: February 23, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A Mistretta, Frank R Korosec, Thomas M Grist, Richard Frayne
  • Patent number: 5713358
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: February 3, 1998
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Frank R. Korosec, Thomas M. Grist, Richard Frayne, Jason A. Polzin