Abstract: A lockable cradle removably supports a device, such as a radiotelephone. The cradle is configured to be locked and unlocked only upon receipt of authorized locking and unlocking signals. A signal receiver is associated with the cradle for receiving locking signals to lock the cradle to prevent removal of the device from the cradle, and for receiving unlocking signals to unlock the cradle to allow removal of the device from the cradle. A signal generator in communication with the signal receiver generates locking and unlocking signals. The signal generator may generate signals responsive to user input or responsive to input from systems external to the device, such as vehicle security and ignition systems.

Abstract: An adjustable carrying assembly for a wireless communication device, such as a radiotelephone. The carrying assembly is comprised of a device support member having a first spring coupled thereto for receiving the communication device and a clip mechanism coupled thereto for mounting the carrier assembly on a user's belt or other article of clothing. The clip mechanism comprises a clip support member, a pin, a clip, a second spring and a cap. One end of clip support member includes an opening with a plurality of grooves arranged in a circular array. The device support member is rotatably attached to the clip support member of the clip mechanism such that when the user rotates the device support member with respect to the clip mechanism, first spring moves from one of the plurality of grooves to another of the plurality of grooves and locks into position.

Abstract: An antenna switch is provided on a portable telecommunication instrument, such as a cellular telephone, to enable operation of the keypad of the instrument when the antenna is extended. In one arrangement, an antenna switch comprises a pair of antenna position sensing contacts disposed on a printed circuit board at a position where electrical continuity is established between the contacts by an electrically conductive member on the antenna when the antenna is in an extended position. The present invention solves the problem of inadvertent activation of the instrument when the antenna is retracted. Thus, the instrument does not require a closeable cover over the keypad to prevent inadvertent actuation of the instrument.

Abstract: The present invention relates generally to mammalian sulphamidase and to genetic sequences encoding same and to the use of these in the investigation, diagnosis and treatment of subjects suspected of or suffering from sulphamidase deficiency.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present intention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: The present invention relates generally to mammalian sulphamidase and to genetic sequences encoding same and to the use of these in the investigation, diagnosis and treatment of subjects suspected of or suffering from sulphamidase deficiency.

Abstract: An antenna extender system includes a means for applying a bias force on the antenna to urge it toward an extended position, and a means for controlling the velocity of the antenna when it is moved from a retracted to the extended position by a constant bias force. The antenna extender system solves the problem of uncontrolled instantaneous extension of antennas in small, mobile telecommunication instruments.

Abstract: This method for detecting a target nucleic acid sequence involves amplification and detection in the same vessel and comprises: (a) amplification of the target nucleic sequence in a vessel which is provided with a solid phase capture probe comprising a nucleic acid sequence capable of hybridizing to at least a portion of said amplified target nucleic acid sequence, said capture probe being incapable of participating or not participating in standard nucleic acid sequence amplification processes, (b) bringing a sample suspected of comprising said target nucleic acid sequence into contact with said capture probe under conditions which allow said amplified target nucleic acid sequence to be bound by said capture probe, and (c) detecting the presence of bound target nucleic acid sequence.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: A circular thin metal or thermoplastic disc stress plate has an annular stiffening rim and groove and a central opening. Three equilateral and symmetrically oriented elongated nail-like members depend from the plate at the rib and groove inclined in diverging relation relative to a vertical axis normal to and central the plate on a conical surface of revolution. The members extend radially beyond the perimeter of the stress plate projected onto the members forming an annular attachment region to a cementitious substrate significantly greater than the area subtended by the stress plate. Two or more than three members may be used in the alternative. The nail-like members have conical tips which may be any shape and blunt. The members preferably are circular cylinder steel, may be other transverse sectional shapes, and are driven individually or simultaneously into the substrate either through holes in the plate or penetrate the plate material by a power operated nail driving tool.

Abstract: Light-emitting diodes are embedded, preferably by insert molding, directly into the translucent elastomeric material forming a keypad or surrounding structure adjacent the light guide of a liquid crystal display panel. The electrical contacts of the LEDs are maintained in bias contact with contact pads provided on the secondary surface of a printed circuit board. The bias contact is preferably provided by a cover assembly which provides a compressive force against the elastomeric keypad when assembled with the printed circuit board and keypad. The present invention enables the construction of a printed circuit board having all of the electrical components disposed on only the primary side of the board, thereby permitting a simpler layout of the electrical circuitry on the PCB and the construction of a thinner keyboard assembly.

Abstract: A marshmallow-based, edible, sheet-like, decorative overlay is formed in situ on a release film mounted on a rigid carrier sheet. After peeling the release film and the overlay together from the carrier sheet, the release film is subsequently peeled from the overlay to enable the overlay to be transferred by itself to a pastry to decorate the same.

Abstract: A buoyant capsule depth controller is presented for positioning and maintaining a capsule within the ocean waters for establishing an observation or defense station. A bouyant capsule is connected to a weight assembly by means of explosive fittings which detonate at a predetermined depth to separate the two. The buoyant capsule and weight assembly are then held together by means of a short line of fixed length until a second predetermined depth is reached, at which time a pressure-actuated release mechanism releases the short line and a cable wound within the weight assembly is payed out to the buoyant capsule below a preset depth as the weight assembly sinks to the ocean floor. The paying out of the cable rotates a shaft within the weight assembly which in turn drives an hydraulic pump, the output of the pump being controlled by a valve to regulate the amount of drag which the pump exerts upon the shaft thus controlling the rate of cable pay out.

Abstract: A load responsive, voltage control current for an A.C. inductor motor wherein the power leads of a triac are connected in series with the motor of an alternating current source of power, and the gate of the triac is connected through an inductor to the power lead interconnecting between the motor and MT2 terminal of a triac. Additionally, means are provided to couple a resistance device across the inductor which varies inversely in resistance responsive to a signal which is responsive to motor loading.

Abstract: Terminal applicator for crimping closed barrel terminals in strip form onto wires has a reciprocable ram, crimping dies on the ram, an anvil for supporting the terminal during crimping, and strip feeding and severing means for feeding terminals to the crimping zone. The anvil is normally in a retracted position and the strip is fed to position the leading terminal of the strip on the housing when the anvil is in its retracted position. Thereafter, the leading terminal is severed from the strip and the anvil is moved to an extended position in which it is at the crimping site. During such movement, a wire held at the crimping site is located in the terminal and upon movement of the dies towards the anvil, the terminal is crimped onto the wire.

Abstract: A machine for inserting displation type terminals in strip form into cavities in a coil bobbin or the like comprises first and second slide assemblies in parallel side-by-side relationship. The strip of terminals is fed towards the insertion zone of the apparatus by a feeding means which is actuated during movement of the first slide member along its working stroke. A shearing means for shearing terminals from the strip is also actuated by the first slide member and this shearing means serves to place the sheared terminals in front of insertion members carried by the second slide member. Finally, during the working stroke of the first slide member, the insertion punches move relative to the second slide towards the insertion zone to advance the sheared terminals in a guide tube on the second slide member.