Patents by Inventor Charles Tabor

Charles Tabor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200237541
    Abstract: A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
    Type: Application
    Filed: April 13, 2020
    Publication date: July 30, 2020
    Inventors: Charles Tabor, Timothy Ryan
  • Patent number: 10672513
    Abstract: Systems for the simulation of percutaneous medical procedures are disclosed. The systems can include a simulated vasculature including a first component configured to allow for introduction of a medical device into the system through an introductory port, a second component connected to the first component and shaped to simulate a portion of a human vasculature, and a third component connected to the second component and shaped to simulate a delivery site for the medical procedure. The system can be configured to allow for a medical device to be delivered to the third component by passing through the introductory port of the first component and passing through the second component. The system can be configured to replicate simulated conditions of use for the medical procedure. Methods for simulating a percutaneous medical procedure using a simulated vasculature are also disclosed.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: June 2, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Dean Christiansen, Joseph Morrow, Charles Tabor
  • Patent number: 10646335
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: May 12, 2020
    Assignee: Medtronic, Inc.
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Anne L. Brody Rubin, Michael J. Tuchek
  • Patent number: 10639182
    Abstract: A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: May 5, 2020
    Assignee: Medtronic, Inc.
    Inventors: Charles Tabor, Timothy Ryan
  • Publication number: 20200113684
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Application
    Filed: December 13, 2019
    Publication date: April 16, 2020
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Anne L. Brody Rubin, Michael J. Tuchek
  • Publication number: 20200030089
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Application
    Filed: July 3, 2019
    Publication date: January 30, 2020
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Anne L. Brody Rubin, Michael J. Tuchek
  • Publication number: 20200017569
    Abstract: The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.
    Type: Application
    Filed: July 24, 2018
    Publication date: January 16, 2020
    Inventors: Kirk J. Leister, Eugene J. Schaefer, Ronald Charles Bates, Elizabeth A. Bramhall, David Michael Didio, Robert Donaldson, Alan R. Flesher, Helen Gray Haggerty, David Henry Kirkley, John Malcolm Tabor, Lee K. Tay, Pallaiah Thammana, Ajoy Velayudhan, David Edward Smolin, Reb J. Russell, Thomas James Vanden Boom, Dean Woodrow Brownell, Jeffrey Schrimsher, Joyce Patricia Whitehead
  • Patent number: 10508144
    Abstract: The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 17, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kirk J. Leister, Eugene J. Schaefer, Ronald Charles Bates, Elizabeth A. Bramhall, David Michael Didio, Robert Donaldson, Alan R. Flesher, Helen Gray Haggerty, David Henry Kirkley, John Malcolm Tabor, Lee K. Tay, Pallaiah Thammana, Ajoy Velayudhan, David Edward Smolin, Reb J. Russell, Thomas James Vanden Boom, Dean Woodrow Brownell, Jeffrey Schrimsher, Joyce Patricia Whitehead
  • Patent number: 10441413
    Abstract: Embodiments of the present invention provide prosthetic valves having sealing members on the external surface thereof. The prosthetic heart valves of the present invention are preferably delivered by catheter directly through the apex of the heart or by other close range transcatheter delivery methods. Because these methods of implantation require a shorter length of catheter, a prosthetic valve can be more accurately oriented in the desired implantation location. Fluoroscopy can be used to further assist in orientation of the valve. The sealing members of the present invention can be positioned on the prosthetic valve such that, when the prosthetic valve is implanted in a native annulus, each provided sealing member is located adjacent to a commissural point of the native valve leaflets. Because the sealing members are precisely oriented on the prosthetic valve, a physician can ensure that the sealing members are aligned with the commissural points of the native valve leaflets.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: October 15, 2019
    Assignee: Medtronic, Inc.
    Inventor: Charles Tabor
  • Patent number: 10378035
    Abstract: Methods of in vitro transcription using cyanophage Syn5 RNA polymerase (RNAP) or mutants thereof and transcription conditions are provided.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: August 13, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Bin Zhu, Charles C. Richardson, Stanley Tabor
  • Publication number: 20190038406
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Application
    Filed: July 10, 2018
    Publication date: February 7, 2019
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Anne L. Brody Rubin, Michael J. Tuchek
  • Publication number: 20180207013
    Abstract: A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
    Type: Application
    Filed: March 21, 2018
    Publication date: July 26, 2018
    Inventors: Charles Tabor, Timothy Ryan
  • Patent number: 10016274
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: July 10, 2018
    Assignee: Medtronic, Inc.
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Ann L. Brody Rubin, Michael J. Tuchek
  • Publication number: 20180144826
    Abstract: Systems for the simulation of percutaneous medical procedures are disclosed. The systems can include a simulated vasculature including a first component configured to allow for introduction of a medical device into the system through an introductory port, a second component connected to the first component and shaped to simulate a portion of a human vasculature, and a third component connected to the second component and shaped to simulate a delivery site for the medical procedure. The system can be configured to allow for a medical device to be delivered to the third component by passing through the introductory port of the first component and passing through the second component. The system can be configured to replicate simulated conditions of use for the medical procedure. Methods for simulating a percutaneous medical procedure using a simulated vasculature are also disclosed.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 24, 2018
    Applicant: MEDTRONIC, INC.
    Inventors: DEAN CHRISTIANSEN, JOSEPH MORROW, CHARLES TABOR
  • Patent number: 9965591
    Abstract: Systems (10) for the simulation of percutaneous medical procedures are disclosed. The systems can include a simulated vasculature including a first component (24) configured to allow for introduction of a medical device into the system through an introductory port, a second component (14) connected to the first component and shaped to simulate a portion of a human vasculature, and a third component (18) connected to the second component and shaped to simulate a delivery site for the medical procedure. The system can be configured to allow for a medical device to be delivered to the third component by passing through the introductory port of the first component and passing through the second component. The system can be configured to replicate simulated conditions of use for the medical procedure. Methods for simulating a percutaneous medical procedure using a simulated vasculature are also disclosed.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: May 8, 2018
    Assignee: MEDTRONIC, INC.
    Inventors: Dean Christiansen, Joseph Morrow, Charles Tabor
  • Patent number: 9925079
    Abstract: A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 27, 2018
    Assignee: Medtronic, Inc.
    Inventors: Charles Tabor, Timothy R. Ryan
  • Publication number: 20170079779
    Abstract: Embodiments of the present invention provide prosthetic valves having sealing members on the external surface thereof. The prosthetic heart valves of the present invention are preferably delivered by catheter directly through the apex of the heart or by other close range transcatheter delivery methods. Because these methods of implantation require a shorter length of catheter, a prosthetic valve can be more accurately oriented in the desired implantation location. Fluoroscopy can be used to further assist in orientation of the valve. The sealing members of the present invention can be positioned on the prosthetic valve such that, when the prosthetic valve is implanted in a native annulus, each provided sealing member is located adjacent to a commissural point of the native valve leaflets. Because the sealing members are precisely oriented on the prosthetic valve, a physician can ensure that the sealing members are aligned with the commissural points of the native valve leaflets.
    Type: Application
    Filed: December 5, 2016
    Publication date: March 23, 2017
    Inventor: Charles Tabor
  • Patent number: 9545306
    Abstract: Embodiments of the present invention provide prosthetic valves having sealing members on the external surface thereof. The prosthetic heart valves of the present invention are preferably delivered by catheter directly through the apex of the heart or by other close range transcatheter delivery methods. Because these methods of implantation require a shorter length of catheter, a prosthetic valve can be more accurately oriented in the desired implantation location. Fluoroscopy can be used to further assist in orientation of the valve. The sealing members of the present invention can be positioned on the prosthetic valve such that, when the prosthetic valve is implanted in a native annulus, each provided sealing member is located adjacent to a commissural point of the native valve leaflets. Because the sealing members are precisely oriented on the prosthetic valve, a physician can ensure that the sealing members are aligned with the commissural points of the native valve leaflets.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: January 17, 2017
    Assignee: Medtronic, Inc.
    Inventor: Charles Tabor
  • Publication number: 20160361184
    Abstract: A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
    Type: Application
    Filed: June 16, 2016
    Publication date: December 15, 2016
    Inventors: Charles Tabor, Timothy R. Ryan
  • Publication number: 20160296328
    Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.
    Type: Application
    Filed: April 14, 2016
    Publication date: October 13, 2016
    Inventors: Charles Tabor, Carol E. Eberhardt, Timothy G. Laske, Timothy R. Ryan, Joseph C. Morrow, Tammy Y. Tam, Brian A. Glynn, Ann L. Brody Rubin, Michael J. Tuchek