Patents by Inventor Chen Hu

Chen Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12286663
    Abstract: A gene editing system of Candida viswanathii includes a Candida viswanathii, a first gene editing fragment and a second gene editing fragment. The first gene editing fragment successively includes a first homology arm and a screening gene. The second gene editing fragment is connected to a C-terminus of the first gene editing fragment and includes a second homology arm, a Cas9 expression cassette and a sgRNA cassette. The Cas9 expression cassette successively includes a Cas9 promoter, a Cas9 gene and three nuclear localization sequences. The sgRNA cassette successively includes a sgRNA promoter, a first ribozyme, a targeting sequence, a scaffold and a second ribozyme. The first gene editing fragment and the second gene editing fragment are constructed as a linear fragment for gene editing of a chromosome of the Candida viswanathii.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: April 29, 2025
    Assignees: NATIONAL TSING HUA UNIVERSITY, Chang Chun Plastics Co., Ltd., Chang Chun Petrochemical Co., LTD., DAIREN CHEMICAL CORP.
    Inventors: Yu-Chen Hu, Nam Ngoc Pham, June-Yen Chou, Hsing-Yun Wang, Vincent Jianan Liu
  • Patent number: 12138965
    Abstract: A tire and a tire wear indicating structure thereof are disclosed. The tire wear indicating structure includes an indicator, at least three inclined portions of different heights, and at least two indicating grooves. The indicator has an indicator depth. The inclined portions are adjacently arranged to each other and located in the indicator. The heights of the inclined portions decrease progressively. The indicating grooves are disposed between the adjacent inclined portions. The indicating grooves each have an indicating groove depth that is the main groove depth minus 1.8 to 2.2 mm and is greater than the indicator depth. The current wear condition of the tire can be seen more intuitively, without too much information interfering with the judgment.
    Type: Grant
    Filed: March 17, 2023
    Date of Patent: November 12, 2024
    Assignee: Cheng Shin Rubber Ind. Co., Ltd.
    Inventors: En-Yu Chang, Man-Chen Hu
  • Publication number: 20240356610
    Abstract: A communication method and apparatus are provided. The method includes: A terminal device receives a first downlink reference signal from a first network device, and the terminal device receives a second downlink reference signal from a second network device. The terminal device determines channel state information. The channel state information is determined based on a ratio of a first channel estimation value to a second channel estimation value. The first channel estimation value is determined based on the first downlink reference signal, and the second channel estimation value is determined based on the second downlink reference signal. The terminal device sends the channel state information.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 24, 2024
    Inventors: Xianda LIU, Chen HU, Shijie CAI, Zhening ZHANG, Kunpeng LIU
  • Patent number: 12115152
    Abstract: The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: October 15, 2024
    Assignee: TARAPEUTICS SCIENCE INC.
    Inventors: Qing Song Liu, Jing Liu, Xi Xiang Li, Ao Li Wang, Zi Ping Qi, Qing Wang Liu, Zong Ru Jiang, Feng Ming Zou, Wen Chao Wang, Chen Hu, Cheng Chen, Li Wang
  • Publication number: 20240227458
    Abstract: A tire and a tire wear indicating structure thereof are disclosed. The tire wear indicating structure includes an indicator, at least three inclined portions of different heights, and at least two indicating grooves. The indicator has an indicator depth. The inclined portions are adjacently arranged to each other and located in the indicator. The heights of the inclined portions decrease progressively. The indicating grooves are disposed between the adjacent inclined portions. The indicating grooves each have an indicating groove depth that is the main groove depth minus 1.8 to 2.2 mm and is greater than the indicator depth. The current wear condition of the tire can be seen more intuitively, without too much information interfering with the judgment.
    Type: Application
    Filed: March 17, 2023
    Publication date: July 11, 2024
    Inventors: EN-YU CHANG, MAN-CHEN HU
  • Publication number: 20240185150
    Abstract: A two-stage stochastic programming based V2G scheduling for operator revenue maximization is provided. Said method aims for the charge/discharge scheduling of electric vehicles, and establishes, based on a distributed renewable energy-storage-EVs charge/discharge power system, a V2G two-stage nonlinear stochastic programming model combining the V2G scheduling randomness with the renewable energy power generation randomness. Said model is converted into a mixed integer linear programming model (MILP) by means of constraint linearization. Furthermore, in order to enable random scenarios to cover uncertainty factors comprehensively, a scenario generation and combination method is designed to combine the V2G scheduling resources with the randomness of the renewable energy level.
    Type: Application
    Filed: April 22, 2021
    Publication date: June 6, 2024
    Applicant: GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCES
    Inventors: Yuping Huang, Chen Hu
  • Publication number: 20240119128
    Abstract: A system includes a hardware processor, and a system memory storing a software code. The hardware processor executes the software code to receive, from a user, a request related to a digital asset, obtain, from the user, verification data for use in creating a record of ownership of the digital asset, create, using the verification data, the record of ownership of the digital asset in an ownership database, embed a digital watermark into the digital asset to generate a digitally watermarked digital asset, and provide, to the user, the digitally watermarked digital asset. The digital watermark embedded in the digitally watermarked digital asset and the record of ownership of the digital asset in the ownership database enable ownership verification of the digital asset.
    Type: Application
    Filed: July 18, 2023
    Publication date: April 11, 2024
    Inventors: Hui Li, Bin Feng, Ni Chia Koay, Chen Hu Wu
  • Publication number: 20240110208
    Abstract: A gene editing system of Candida viswanathii includes a Candida viswanathii, a first gene editing fragment and a second gene editing fragment. The first gene editing fragment successively includes a first homology arm and a screening gene. The second gene editing fragment is connected to a C-terminus of the first gene editing fragment and includes a second homology arm, a Cas9 expression cassette and a sgRNA cassette. The Cas9 expression cassette successively includes a Cas9 promoter, a Cas9 gene and three nuclear localization sequences. The sgRNA cassette successively includes a sgRNA promoter, a first ribozyme, a targeting sequence, a scaffold and a second ribozyme. The first gene editing fragment and the second gene editing fragment are constructed as a linear fragment for gene editing of a chromosome of the Candida viswanathii.
    Type: Application
    Filed: March 24, 2023
    Publication date: April 4, 2024
    Inventors: Yu-Chen HU, Nam Ngoc PHAM, June-Yen CHOU, Hsing-Yun WANG, Vincent Jianan LIU
  • Patent number: 11932698
    Abstract: Described herein are T cells engineered to express a chimeric antigen receptor (CAR), such as an anti-mesothelin CAR alone or in combination with a follicle-stimulating hormone receptor (FSHR) binding domain and/or a dominant negative transforming growth factor-? receptor II (dnTGF?RII) for the treatment of diseases associated with mesothelin expression. Also described are T cells engineered to express a modified T cell receptor (TCR).
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 19, 2024
    Assignee: Nanjing Legend Biotech Co., Ltd.
    Inventors: Qing Dai, Jian Liu, Shuai Yang, Kun Jiang, Yuanyuan Peng, Chen Hu, Shu Wu
  • Patent number: 11913055
    Abstract: Disclosed herein relates to biopharmaceuticals, and more particularly to a continuous flow method for preparing (R)-3-hydroxy-5-hexenoate. Carbonyl reductase and isopropanol dehydrogenase are co-immobilized onto an inert solid medium simultaneously to prepare a carbonyl reductase/isopropanol dehydrogenase co-immobilized catalyst, which is then filled into a microchannel reactor of the micro reaction system. A solution containing substrate 3-carbonyl-5-hexenoate is subsequently pumped into the microchannel reactor to perform an asymmetric carbonyl reduction reaction to obtain (R)-3-hydroxy-5-hexenoate.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: February 27, 2024
    Assignee: Fudan University
    Inventors: Fener Chen, Dang Cheng, Zedu Huang, Chen Hu, Meifen Jiang, Minjie Liu, Huashan Huang
  • Publication number: 20230416221
    Abstract: A kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. A method and a use for using the inhibitor for treatment of diseases related to CDK9 and/or mutagenic activity thereof.
    Type: Application
    Filed: October 21, 2021
    Publication date: December 28, 2023
    Applicant: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES
    Inventors: Qingsong LIU, Jing LIU, Yun WU, Beilei WANG, Aoli WANG, Chen HU, Qingwang LIU, Fengming ZOU, Wenchao WANG, Zuowei WANG, Jiangyan CAO, Chenliang SHI, Li WANG
  • Publication number: 20230411976
    Abstract: A mobile power supply system includes a mobile power supply management device and one or more cascaded mobile power supplies. The mobile power supply includes a battery and a battery control circuit. The mobile power supply management device includes at least one of a direct-current discharge circuit and an alternating-current discharge circuit. The mobile power supply management device is used for managing charging and discharging of a battery of the mobile power supply. The mobile power supply management device and the one or more cascaded mobile power supplies are detachably and mechanically connected. The number and power of the mobile power supplies of the mobile power supply system can be adjusted according to requirements, and different battery capacities and discharging capacities are achieved.
    Type: Application
    Filed: June 19, 2023
    Publication date: December 21, 2023
    Inventors: Jiankun ZHAO, Chen HU, Jinsheng ZHU
  • Publication number: 20230235338
    Abstract: A gene editing system of Escherichia coli includes an Escherichia coli, a helper plasmid and a donor plasmid. The helper plasmid successively includes a transposase complex expression cassette, a Cas12k expression cassette, a first sgRNA cassette, a first antibiotic resistance gene and a first replication origin. The donor plasmid successively includes a left end sequence of a ShCAST transposon, an exogenous gene expression cassette, a right end sequence of the ShCAST transposon, a second sgRNA cassette, a second antibiotic resistance gene and a second replication origin.
    Type: Application
    Filed: August 4, 2022
    Publication date: July 27, 2023
    Inventors: Yu-Chen Hu, Chin-Wei Chang, Jing-Wen Huang, June-Yen Chou
  • Publication number: 20230186196
    Abstract: A system includes a computing platform having processing hardware and a memory storing software code. The processing hardware executes the software code to receive content data identifying new content and a future release date for the new content, provide a prediction identifying a subset of the users likely to request the new content upon its release, and prioritize, based on the prediction, a schedule for pre-provisioning authentication data for accessing the new content to the subset of users. The processing hardware further executes the software code to pre-provision, using the prioritized schedule, the authentication data to the subset of users prior to the release of the new content.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 15, 2023
    Inventors: Hui Li, Chen Hu Wu
  • Patent number: 11602534
    Abstract: The present invention relates to a kinase inhibitor, comprising a compound of Formula I or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also relates to a pharmaceutical composition comprising the kinase inhibitor, and to uses and methods for using these compounds and compositions to inhibit the activity of wild-type FLT3, mutant FLT3-ITD, PDGFR? and/or PDGFR? kinase in a cell or a subject, as well as uses and methods of these compounds and compositions to preventing or treating kinase-associated conditions in a subject.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 14, 2023
    Assignee: Hefei Institutes of Physical Science, Chinese Academy of Sciences
    Inventors: Qingsong Liu, Jing Liu, Xiaofei Liang, Beilei Wang, Kailin Yu, Zongru Jiang, Cheng Chen, Chen Hu, Wenchao Wang, Fengming Zou, Qingwang Liu, Feng Li, Wenliang Wang, Li Wang
  • Publication number: 20230075679
    Abstract: The present disclosure provides a temperature measurement method, a temperature measurement device, an electronic apparatus and a computer-readable storage medium. The method includes obtaining an image frame pair including a target object by a visible light camera and a thermal imaging camera, and a blackbody being also set in an image acquisition region of the thermal imaging camera; determining a measured temperature of the target object based on the image frame pair; performing a blackbody detection on the infrared image to obtain a detection result of the blackbody; determining a measured temperature of the blackbody based on the detection result of the blackbody and the infrared image; and correcting the measured temperature of the target object according to the measured temperature of the blackbody and a preset temperature of the blackbody, a corrected temperature being used as a temperature measurement result of the target object.
    Type: Application
    Filed: September 30, 2020
    Publication date: March 9, 2023
    Inventors: Yaowei ZHANG, Chen HU, Shuchang ZHOU
  • Patent number: 11578346
    Abstract: The present disclosure relates to a transformant for producing 2,5-furandicarboxylic acid. The transformant for producing 2,5-furandicarboxylic acid includes a Pseudomonas putida and at least one exogenous gene. The exogenous gene is an HmfH gene or an HMFO gene, and the exogenous gene is integrated into the chromosome of the Pseudomonas putida.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: February 14, 2023
    Assignees: National Tsing Hua University, Chang Chun Plastics Co., Ltd., Chang Chun Petrochemical Co., Ltd., Dairen Chemical Corp.
    Inventors: Yu-Chen Hu, Nam Ngoc Pham
  • Patent number: D984244
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: April 25, 2023
    Assignee: GETAC TECHNOLOGY CORPORATION
    Inventors: Yu-Chin Wu, Hsien-Chen Hu
  • Patent number: D993748
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: August 1, 2023
    Assignee: GETAC TECHNOLOGY CORPORATION
    Inventors: Yu-Chin Wu, Hsien-Chen Hu
  • Patent number: D1048305
    Type: Grant
    Filed: July 25, 2023
    Date of Patent: October 22, 2024
    Inventors: Weijian Wu, Chen Hu, Shouwu Huang