Abstract: The present invention provides methods and systems for formulation optimization of bispecific antibodies. The present application also provides methods and systems to select molecule candidates for constructing bispecific antibodies and formulation optimization thereof. Physico-chemical parameters of a bispecific antibody are characterized. The formulation optimization strategies are guided by the prediction of interaction parameters. Various formulation optimization strategies are provided based on these physico-chemical parameters.

Abstract: Interstitially modified compounds of rare earth element-containing, iron-rich compounds may be synthesized with a ThMn12 tetragonal crystal structure such that the compounds have useful permanent magnet properties. It is difficult to consolidate particles of the compounds into a bulk shape without altering the composition and magnetic properties of the metastable material. A combination of thermal analysis and crystal structure analysis of each compound may be used to establish heating and consolidation parameters for sintering of the particles into useful magnet shapes.

Abstract: At least one XML document to be validated is parsed, and XML data in the at least one XML document is represented as data objects in at least one data object model in a memory. At least one rule document is parsed and a rule object model that includes rule objects is created in the memory. At least part of the data objects are extracted from the at least one data object model and at least part of rule objects are extracted from the rule object model. Partial validation is performed in a corresponding execution context that validates the extracted at least part of the data objects based upon the extracted at least part of the rule objects.

Abstract: At least one XML document to be validated is parsed, and XML data in the at least one XML document is represented as data objects in at least one data object model in a memory. At least one rule document is parsed and a rule object model that includes rule objects is created in the memory. At least part of the data objects are extracted from the at least one data object model and at least part of rule objects are extracted from the rule object model. Partial validation is performed in a corresponding execution context that validates the extracted at least part of the data objects based upon the extracted at least part of the rule objects.

Abstract: A method, system, and computer program product for graph-based searching for one or more data streams is disclosed. A computer-implemented method comprises extracting a plurality of tuples from one or more data streams. The method further comprises generating a graph for the plurality of tuples in which a node represents a tuple of the plurality of tuples and an edge represents a correlation between the node and another node, and the edge is generated based at least partly on one or more predetermined queries for the one or more data streams. The method further comprises traversing the graph based on the one or more predetermined queries. Accordingly, embodiments of the present disclosure can improve the search speed by use of the graph-based searching for one or more data streams.

Abstract: Methods of manufacturing electrically conductive copper components for electric devices and method of joining electrically conductive copper components are provided. Each of the electrically conductive copper components are manufactured to include a preexisting coating of joining material located on or adjacent to a joining surface thereof.

Abstract: A vehicle cleaning system for cleaning a vehicle including a processor and a memory including computer-executable instructions that, when executed by the processor, cause the processor to perform operations. The operations include determining that a passenger compartment of the vehicle requires cleaning and identifying a type of cleaning required. The operations also include that at least one of a fragrance system, a dry particulate removal system, and a wet particulate removal system is activated in response to the type of cleaning required.

Abstract: The invention relates to petroleum seismic exploration, and more specifically to a method for gas-bearing reservoir characterization using logging information. In the method, logging information is used as a constraint to indirectly characterize the distribution range of the gas-bearing reservoir by determining the upper and lower boundaries. In addition, this method enables the automatic determination of the optimal calculation parameters according to the characteristics of input data, allowing for more accurate results.

Abstract: A method, system, and computer product for anomaly detection in a sensor network. The method comprises: receiving measurements from a plurality of sensors in the sensor network. The method further comprises performing a graph Fourier transform on the measurements to obtain a spectrum. The graph Fourier transform is defined by a graph structure generated from the plurality of sensors. The method further comprises generating an anomaly alert in response to high frequency components of the spectrum exceeding a first threshold.

Abstract: A planar waveguide device (PWD) for interacting with a fluid (FLD) is disclosed, the planar waveguide device (PWD) comprising a waveguide layer (WGL) for supporting optical confinement, a coupling arrangement (CPA) for in-coupling and out-coupling of light into and from the waveguide layer (WGL), a fluid zone (FZN) for accommodating the fluid (FLD), a filter layer (FTL) arranged between the fluid zone (FZN) and the waveguide layer (WGL) in an interaction region (IAR) of the waveguide layer (WGL), wherein the filter layer (FTL) comprises filter openings (FOP) arranged to allow the fluid (FLD) to interact with an evanescent field of light guided by the waveguide layer (WGL), wherein the filter openings (FOP) are adapted to prevent particles (PAR) larger than a predefined size from interacting with said evanescent field, wherein the filter openings (FOP) are arranged as line openings having their longitudinal direction in parallel with the direction of propagation (DOP) of light guided by the waveguide lay

Abstract: Implementations of the subject matter described herein provide a solution for thin object detection based on computer vision technology. In the solution, a plurality of images containing at least one thin object to be detected are obtained. A plurality of edges are extracted from the plurality of images, and respective depths of the plurality of edges are determined. In addition, the at least one thin object contained in the plurality of images is identified based on the respective depths of the plurality of edges, the identified at least one thin object being represented by at least one of the plurality of edges. The at least one thin object is an object with a significantly small ratio of cross-sectional area to length. It is usually difficult to detect such thin object with a conventional detection solution, but the implementations of the present disclosure effectively solve this problem.

Abstract: The invention relates to petroleum seismic exploration, and more specifically to a method for gas-bearing reservoir characterization using logging information. In the method, logging information is used as a constraint to indirectly characterize the distribution range of the gas-bearing reservoir by determining the upper and lower boundaries. In addition, this method enables the automatic determination of the optimal calculation parameters according to the characteristics of input data, allowing for more accurate results.

Abstract: According to aspects of the present disclosure, a method includes selecting a faying surface of a first metal substrate, placing a reaction material on the faying surface, and attaching, prior to a second metal substrate being adjacent the first metal substrate, the reaction material to the faying surface via ultrasonic welding. The reaction material is configured to form a metallurgical joint between the faying surface and the second metal substrate adjacent the first metal substrate.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to managing interrupting requests to engage in a collaborative session and provide a novel and non-obvious method, system and computer program product for host state sensing for message interruptions. In one embodiment of the invention, a data processing system configured for host sensing for message interruption can include a messenger disposed is a host computing platform, prioritization logic including program code enabled to assign priorities to incoming messages, and host state sensing logic coupled to the host computing platform. The host state sensing logic can include program code enabled to adjust a threshold value for permitting message interruptions for messages having assigned priorities beyond the threshold value.

Abstract: Techniques for parsing a message comprising at least one data field are provided. One computer-implemented method comprises: determining, by an electronic device operatively coupled to a processing unit, a first model from a first category of data processing models; and determining, by the electronic device, a second model from a second category of data processing models, the second category being different from the first category. The computer-implemented method also comprises comparing, by the electronic device, performance of a first combined model of first and second models with performance of the first model; and selecting, by the electronic device, a target model for processing data from the first combined model and the first model based on the comparing.

Abstract: A method of forming a weld interface between a first workpiece and a second workpiece includes arranging a reactive braze material at a first joining surface of the first workpiece. The reactive material is selected to react upon being heated to a temperature below the solidus temperature of the first and second workpieces to form a liquid-containing reaction product. Furthermore, an assembly is prepared of the first workpiece and the second workpiece with the first joining surface of the first workpiece and a second joining surface of the second workpiece separated by the reactive material. The second workpiece is then heated with a first laser beam following a first path and with a second laser beam following a second path.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to managing interrupting requests to engage in a collaborative session and provide a novel and non-obvious method, system and computer program product for host state sensing for message interruptions. In one embodiment of the invention, a data processing system configured for host sensing for message interruption can include a messenger disposed is a host computing platform, prioritization logic including program code enabled to assign priorities to incoming messages, and host state sensing logic coupled to the host computing platform. The host state sensing logic can include program code enabled to adjust a threshold value for permitting message interruptions for messages having assigned priorities beyond the threshold value.

Abstract: Methods and systems are provided for ranking search results and generating a presentation. In some implementations, a search system generates a presentation based on a search query. In some implementations, a search system ranks search results based on data stored in a knowledge graph. In some implementations, a search system identifies a modifying concept such as a superlative in a received search query, and determines ranking properties based on the modifying concept.

Abstract: A thyristor valve test system based on cooperation of logic functions of software, wherein the test system comprises: a thyristor valve (5) to be tested, a VBE (3) and a tester (4), and the VBE (3) has a dedicated test mode, the tester (4) provides three steps for each test item. The thyristor valve (5) to be tested and the VBE (3) are connected by optical fibers (1), and the thyristor valve (5) to be tested and the tester (4) are connected by cables (2), and there is no connection between the VBE (3) and the tester (4).

Abstract: At least one XML document to be validated is parsed, and XML data in the at least one XML document is represented as data objects in at least one data object model in a memory. At least one rule document is parsed and a rule object model that includes rule objects is created in the memory. At least part of the data objects are extracted from the at least one data object model and at least part of rule objects are extracted from the rule object model. Partial validation is performed in a corresponding execution context that validates the extracted at least part of the data objects based upon the extracted at least part of the rule objects.