Abstract: The present disclosure relates to compositions and methods for enhancing infiltration of lymphocytes into tumor tissue, enhancing anti-tumor lymphocyte activities in tumor microenvionment (TME), inhibiting regulatory lymphocyte (e.g., B and T cells) activities in TME, and/or long term benefit of cell therapies. For example, in a method of in vivo cell expansion, the method comprises administering an effective amount of cells comprising an antigen binding molecule to a subject; and administering an effective amount of presenting cells expressing a solid tumor antigen that the binding molecule binds.

Abstract: A left atrial appendage occluder (200) comprises a sealing part (220), a fixing part (210) disposed at one side of the sealing part (220), and a connection part (230) for connecting the sealing part (220) and the fixing part (210). The radial deformation capacity of the sealing part (220) is greater than the radial deformation capacity of the fixing part (210), and/or, the axial deformation capacity of the sealing part (220) is greater than the axial deformation capacity of the fixing part (210). In the left atrial appendage occluder (200), the radial or axial deformation capacity of the sealing part (220) is configured to be greater than the radial or axial deformation capacity of the fixing part (210), thereby avoiding the situation in which the sealing part (220) is not optimally fitted with the opening of the left atrial appendage (10) when the fixing part (210) is placed inside of the left atrial appendage (10), which in turn enhances the occlusion effect.

Abstract: The memory device includes a memory block, which includes a plurality of memory cells arranged in a plurality of word lines. The memory device also includes control circuitry in communication with the memory block. The control circuitry is configured to perform a programming operation to program the memory cells of a selected word line of the plurality of word lines. During the programming operation, the control circuitry is configured to apply a programming pulse VPGM to a selected word line to the selected word line, apply a first pass voltage to a first set of word lines of the plurality of word lines, the first set of word lines being adjacent the selected word line, and apply a second pass voltage to a second set of word lines of the plurality of word. The first pass voltage is greater than the second pass voltage.

Abstract: Provided are an LED chip and a light emitting device, which include a light emitting epitaxial layer, a first insulating layer covering the light emitting epitaxial layer, and a first pad and a second pad located on the first insulating layer. Each of the first pad and the second pad includes a stress buffer layer, a nickel metal layer, and a protective layer. The stress buffer layer includes aluminum metal layers; and by adjusting the thickness distribution of the aluminum metal layers, an aluminum metal layer closest to the nickel metal layer is set to be the thickest, and the aluminum metal layers are thickened, especially the thickness of the aluminum metal layer closest to the nickel metal layer is greater than or equal to the thickness of the nickel metal layer, therefore, the ductility and tensile property of aluminum metal are utilized to play a role in stress buffering.

Abstract: A retaining sheet is used for retaining to a slat of a venetian blind. The slat has a through hole for penetration of a lifting cord. The retaining sheet includes a main body with an upper surface, a lower surface, a hole, and a slot. The hole and the slot pass through the upper and bottom surfaces of the main body and communicate with each other. The width of the slot is smaller than the width of the hole, wherein the main body is configured when the retaining sheet is retained to the slat of the venetian blind, the hole of the main body corresponds to the through hole of the slat, and the lifting cord is penetrated through the hole and inserted into the slot when pulled by an external force. This can prevent the lifting cord from being drawn out for enhancing the safety of use.

Abstract: Systems, methods, and devices are described herein for pre-setting scan flip-flops using combinational logic circuits. A system includes a plurality of flip-flop devices and a first pre-setting combinational logic circuit. The plurality of flip-flop devices are coupled together in series and configured to receive a scan input signal, capture data output from each flip-flop device of the plurality of flip-flop devices based on the scan input signal, and generate a scan output signal comprising the captured data. The first pre-setting combinational logic circuit is coupled to a first flip-flop device of the plurality of flip-flop devices. The first pre-setting combinational logic circuit includes a plurality of transistors and is configured to override and set either the scan input signal to the first flip-flop device or the scan output signal of the first flip-flop device based on selective operation of the plurality of transistors.

Abstract: An optical element driving mechanism is provided. The optical element driving mechanism includes a movable portion used for connecting an optical element, a fixed portion, and a driving assembly used for driving the movable portion to move relative to the fixed portion. The movable portion is movable relative to the fixed portion.

Abstract: Disclosed herein are polyurethane foams which can be used for reducing or preventing the corrosion of polymeric materials, which can be produced by mixing components (a) at least one polyisocyanate, (b) at least one compound having at least two groups reactive toward isocyanates, (c) optionally chain extender and/or crosslinking agent, (d) blowing agent, (e) catalyst, (f) optionally auxiliaries and additives, and (g) at least one anhydride to give a reaction mixture, and curing said reaction mixture to give the polyurethane foams, where the anhydride is added in an amount of 0.05-5 wt %, based on the weight of component (a). Also disclosed herein are a method of reducing or preventing the corrosion of polymeric materials by using such polyurethane foams and a method of using the polyurethane foams in certain applications, for example, in automotive interiors.

Abstract: The battery module includes a plurality of battery cells electrically connected to one another, a silicone rubber foam at least partially covering the plurality of battery cells, and a flame barrier sheet at least partially covering the plurality of battery cells. The process includes dispensing a silicone rubber foam composition on at least one of the plurality of battery cells or the flame barrier sheet and placing the flame barrier sheet on the plurality of battery cells.

Abstract: The present invention relates to electrode tabs and batteries. The electrode tab includes a first metal strip and a metal connector connected to the first metal strip. A melting point of the metal connector is lower than a melting point of the first metal strip, or a solidus temperature of the metal connector is lower than a solidus temperature of the first metal strip, or a liquidus temperature of the metal connector is lower than a liquidus temperature of the first metal strip. The electrode tab has the advantages of regular shape, which are not only easy to install and assemble, saving assembly costs, but also not easy to be damaged in the process of assembly, transportation and storage. The electrode tab does not affect an overall size of the battery, is more suitable for use in scenarios such as small miniature batteries and power batteries.

Abstract: Methods for labeling and imaging the accessible genome using a transposase are disclosed. In some embodiments, a bifunctional transposase complex or transposome is used to insert adaptors comprising chemical tags selectively at accessible sites in the genome where active regulatory DNA is located. Various chemical tags can be used for labeling DNA at insertion sites, including, for example, fluorescent dyes for fluorescence imaging, metal particles for electron microscopy or magnetic manipulation of DNA, isotopic labels, or biotin or other ligands, haptens, substrates, or inhibitors that are recognized by streptavidin, antibodies, enzymes, or receptors. Labeling DNA in this manner can be used to provide spatial information regarding the positioning of regulatory DNA in the genome and makes possible the imaging and sorting of cells based on the status of their regulatory DNA.

Abstract: Disclosed embodiments relate to accelerating multiplication of sparse matrices. In one example, a processor is to fetch and decode an instruction having fields to specify locations of first, second, and third matrices, and an opcode indicating the processor is to multiply and accumulate matching non-zero (NZ) elements of the first and second matrices with corresponding elements of the third matrix, and executing the decoded instruction as per the opcode to generate NZ bitmasks for the first and second matrices, broadcast up to two NZ elements at a time from each row of the first matrix and each column of the second matrix to a processing engine (PE) grid, each PE to multiply and accumulate matching NZ elements of the first and second matrices with corresponding elements of the third matrix. Each PE further to store an NZ element for use in a subsequent multiplications.

Abstract: The present invention provides an optimization control method for an aero-engine transient state based on reinforcement learning, and belongs to the technical field of aero-engine transient states. The method comprises: adjusting an existing twin-spool turbo-fan engine model as a model for invoking a reinforcement learning algorithm; to simultaneously satisfy high level state space and continuous action output of a real-time model, designing an Actor-Critic network model; designing a deep deterministic policy gradient (DDPG) algorithm based on an Actor-Critic frame, to simultaneously solve the problems of high-dimensional state space and continuous action output; training the model after combining the Actor-Critic frame with the DDPG algorithm; and obtaining the control law of engine acceleration transition from the above training process, and using the method to control an engine acceleration process.

Abstract: A method for surgery planning is provided. The method may include: generating a surgery video displaying a process of a virtual surgery performed by a virtual surgical robot on a virtual patient based on a surgery plan relating to a robotic surgery to be performed on a patient by a surgical robot; transmitting the surgery video to a display component of an XR assembly used to render the surgery video for display to a user; recording one or more actions that the user performed on the virtual surgery based on user input received via an input component of the XR assembly; modifying the surgery plan based on the one or more recorded actions; and causing the surgical robot to implement the robotic surgery on the patient according to the modified surgery plan.

Abstract: A foot protection pad is provided, comprising: a body, a midfoot elastic body and a heel elastic body; wherein, the body is formed with a first elastic material to form a front plantar area, a midfoot area and a heel area; the bottom surface of the midfoot area is formed with a midfoot arch, and opposite sides are formed with a concave arc surface of the inner arch and the concave arc surface of the outer arch; a recession is formed on the body of the heel area, and the opposite two sides of the recession are formed with a concave arc surface of the inner arch and a concave arc surface of the outer arch, and the rear end is formed with a heel concave arc surface; the midfoot elastic body and the heel elastic body are formed with a second elastic material and respectively combined with the body.

Abstract: A vertical clamping substrate jig includes a jig body including an upper frame plate, a lower frame plate, a first side frame plate and a second side frame plate and the upper frame plate, the first side frame plate and the second side frame plate each having two through holes, a plurality of fixing structures set next to the through holes respectively, a plurality of clamping members respectively set on the upper frame plate, the first side frame plate and the second side frame plate, and supporting members used to support the upright flexible substrate that has a thickness in between 0.2 mm to 3 mm. Each clamping member has one end thereof connected to one respective fixing structure, an opposite end terminating in a clamping end, and an elastic portion on the middle between the two ends.

Abstract: A setting method of in-memory computing simulator includes: performing a plurality of test combinations by an in-memory computing device and recording a plurality of first estimation indices corresponding to the plurality of test combinations respectively, wherein each of the plurality of test combinations includes one of a plurality of neural network models and one of a plurality of datasets, executing a simulator according to the plurality of test combinations by a processing device and recording a plurality of second estimation indices corresponding to the plurality of test combinations respectively, wherein the simulator has a plurality of adjustable settings; calculating a correlation sum according to the plurality of first estimation indices and the plurality of second estimation indices by the processing device, and performing an optimal algorithm to search an optimal parameter in the setting space constructed by the plurality of settings so that the correlation sum is maximal.

Abstract: A modified positive electrode material includes an inner core and a cladding layer. The inner core is a positive electrode material, and the cladding layer includes a polymer electrolyte body and a ferroelectric ceramic material dispersed in the polymer electrolyte body.

Abstract: Provided are compounds of Formula Ir(LA)x(LC)y wherein: ligand LA has Formula I? ?and ligand LC has Formula II?

Abstract: A manufacturing method of a multi-screen display is provided. The manufacturing method includes the following steps. A first panel is provided. A second panel is provided. The first panel and the second panel are spliced. The first color coordinate of the first panel includes a first horizontal coordinate and a first vertical coordinate, and the second color coordinate of the second panel includes a second horizontal coordinate and a second vertical coordinate. The difference between the horizontal coordinate and the second horizontal coordinate is ?x, the difference between the first vertical coordinate and the second vertical coordinate is ?y, and ?x and ?y satisfy the following relationship: ?=arctan(?x/?y), 46 degrees???126 degrees.