Patents by Inventor Cheng Ji

Cheng Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6206552
    Abstract: An anti-luxation device for clasper of power-supply wires in a lamp string, which mainly comprises a clasper of socket; the clasper includes a wide wall plate and a top flat surface, between which an arm plate extends outwards, and the tail end of the arm plate has a hook hole; the arm plate is connected with the clasper by means of a bendable thin plate; after the arm plate is bent upwards, it will be in contact with the hook furnished and extended out between the cylindrical surface of the socket and the top flat surface, and then the hook hole and the hook can be mated together with a light pressing force without luxation between the clasper and the socket upon the power-supply wires being pulled unintentionally.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: March 27, 2001
    Inventor: Cheng-Ji Kuo
  • Patent number: 6024718
    Abstract: An ultrasound catheter comprises a coaxial cable of electrical conductors with a piezoelectric element at its distal end. The piezoelectric element is shaped and disposed according to the desired ultrasonic field. When an electrical signal from a signal generator is connected to the electrical conductors, the piezoelectric element mechanically deforms in response and generates ultrasonic energy. An alternative embodiment of the present invention is a hollow tubular catheter of flexible polymer has at its distal end a cylindrical piezoelectric element connected to electrical conductors running the length of the catheter. The piezoelectric cylinder may be tapered, segmented, shortened, etc. according to the desired focusing of the ultrasonic field, which is preferably forwardly focused. In either embodiment the catheter is threaded through a patient's vasculature and brought in close proximity to a vascular occlusion.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: February 15, 2000
    Assignee: The Regents of the University of California
    Inventors: Hank H. Chen, Cheng Ji
  • Patent number: 6011995
    Abstract: Hyperthermic treatment of tissue such as cancer tumors, is realized by providing an ohmic heating element on the distal tip of a catheter endovascularly inserted upstream of the tissue. Electrical power is provided to the element for a selected time and degree to raise the temperature of blood to a thermally mediating level such as 42.degree. C., but not to heat the blood so that distal tissues downstream are adversely affected. The element comprises a helical coil heater disposed proximate to the end of a catheter and within an expandable cage. The cage can be selectively deployed by expanding it to maintain the coil out of contact with the vessel walls while still allowing free blood flow. Alternatively a guidewire within an expandable cage can be disposed within the same catheter wherein the heating coil has been wound onto the guidewire or the guidewire is uninsulated at that portion within the cage serves as an electrode to directly heat the blood.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: January 4, 2000
    Assignee: The Regents of the University of California
    Inventors: Guido Guglielmi, Cheng Ji
  • Patent number: 5976131
    Abstract: An apparatus is provided for electrocoagulating blood and tissue at an occlusion site by means of application of an alternating signal or current through a detachable partially insulated coil on the end of a microcatheter. A Guglielmi Detachable Coil (GDC) is preferably used in the combination with damped radio frequency energy to cause local heating at the location of the coil but without local ohmicly heated tissue damage or hot spots. Damping of the radio frequency energy facilitates the avoidance of hot spots. Once carbonization of blood at the detachment zone of the GDC coil occurs, the impedance of the entire system increases. The impedance increase is detected to automatically turn off the alternating current and then to apply a direct current to electrolytically detach the GDC coil from the microcatheter.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: November 2, 1999
    Assignee: The Regents of the University at California
    Inventors: Guido Guglielmi, Cheng Ji
  • Patent number: 5919187
    Abstract: A thrombus is generated in an aneurysm, arteriovenous malformation or fistula by means of a catheter having an insulated heating coil coupled to an insulated delivery wire. In one embodiment, two delivery wires are coupled to heating coils to provide a closed circuit. The heating coils may be in the form of a double helix or a single helix in combination with a straight heating coil. The heating coils are permanently connected to the delivery wires. Alternatively, a single insulated heating coil may be attached to a single insulated delivery wire with a uninsulated coil attached to the tip of the insulated heating coil. The electrical circuit is then made through the heating coil and non-insulated electrode coil into the vascular system and to a body electrode. A catheter may also be used for heating blood within the vascular system which is directly flowed into a tumoral mass for the purposes of thermal treatment of cancer.
    Type: Grant
    Filed: September 15, 1995
    Date of Patent: July 6, 1999
    Assignee: The Regents of the University of California
    Inventors: Guido Guglielmi, Cheng Ji
  • Patent number: 5894022
    Abstract: The present invention is an endovascular embolic composition. The embolic composition comprises a hydrophilic insoluble matrix having a microscopic mesh-like structure. The voids or intricacies of the matrix enclose droplets of aqueous solution as well as liquid oil. This structure is essentially equivalent to a "gel" structure with the insoluble matrix including both aqueous and oil droplets within its mesh. In creating the matrix a liquid oil base is mixed with an aqueous solution of a matrix base. The matrix base comprises an organic polymer such as a protein like albumin or its equivalent dissolved in an aqueous solution which may contain additional solutes. The matrix base solution is mixed and emulsified with the liquid oil base at a volume ratio ranging between about 1-to-1 and 1-to-5 respectively.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: April 13, 1999
    Assignee: The Regents of the University of California
    Inventors: Cheng Ji, Guido Guglielmi
  • Patent number: 5888546
    Abstract: A multipurpose ointment (MPOc) in a semisolid-semiliquid form and a multipurpose particle (MPPc) in a solid soft particulate form are prepared by combining a matrix base in a aqueous solution with a liquid oil base and added modifiers and medications to form either an ointment or suspension of particles for endovascular disposition for embolizing abnormal microvascular beds or nidi. The ointment or particles are formed from a albumin (human serum or chicken egg) matrix or equivalent material or combination of the same in an aqueous solution, typically contrast-medium solution, which has been emulsified with a radiopaque oil base such as ETHIODOL, and then heated to modify the mobility, viscosity, deformability, elasticity, surface tension and friction along with the inclusion of medications and modifiers for the desired physical characteristics and biological end effects.
    Type: Grant
    Filed: August 28, 1995
    Date of Patent: March 30, 1999
    Assignee: The Regents of the University of California
    Inventors: Cheng Ji, Guido Guglielmi
  • Patent number: 5851206
    Abstract: A trombus is generated in an aneurysm, arteriovenous malformation or fistula by means of a catheter having an insulated heating coil coupled to an insulated delivery wire. In one embodiment, two delivery wires are coupled to heating coils to provide a closed circuit. The heating coils may be in the form of a double helix or a single helix in combination with a straight heating coil. The heating coils may be electrolytically or mechanically detached therefrom. Alternatively, a single insulated heating coil may be attached to a single insulated delivery wire with a uninsulated coil attached to the tip of the insulated heating coil. The electrical circuit is then made through the heating coil and non-insulated electrode coil into the vascular system and to a body electrode. A catheter may also be used for heating blood within the vascular system which is directly flowed into a tumoral mass for the purposes of thermal treatment of cancer.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: December 22, 1998
    Assignee: The Regents of the University of California
    Inventors: Guido Guglielmi, Cheng Ji
  • Patent number: 5743905
    Abstract: This is a device used in the occlusion of various lumen and other cavities in the body. In particular, it may be used to form an endovascular occlusion through the application of a radio-frequency modulated voltage to the device after its placement in the body. The elongated device is distally insulated to optimize its occlusive activity without harm to the body.
    Type: Grant
    Filed: February 27, 1996
    Date of Patent: April 28, 1998
    Assignee: Target Therapeutics, Inc.
    Inventors: Joseph Eder, Guido Guglielmi, Cheng Ji
  • Patent number: 5569245
    Abstract: An apparatus is provided for electrocoagulating blood and tissue at an occlusion site by means of application of an alternating signal or current through a detachable coil on the end of a microcatheter. A Guglielmi Detachable Coil (GDC) is preferably used in the combination with radio frequency energy to cause local heating at the coil. Once carbonization of blood at the detachment zone of the GDC coil occurs, the impedance of the entire system increases. The impedance increase is detected to automatically turn off the alternating current and then to apply a direct current to electrolytically detach the GDC coil from the microcatheter.
    Type: Grant
    Filed: October 17, 1994
    Date of Patent: October 29, 1996
    Assignee: The Regents of the University of California
    Inventors: Guido Guglielmi, Cheng Ji