Abstract: The present invention relates to a conjugate for preventing and treating viral infections and a use thereof, and in particular, to a protein-anti-influenza compound conjugate having a structure of formula I-1 or a pharmaceutically acceptable salt, an ester, an isomer, a solvate, a prodrug or an isotope label thereof. The conjugate has small molecules (D1 and D2) linked, by means of linkers (L1 and L2) to an Fc monomer, an Fc domain, an Fc linker peptide, an albumin or an albumin linker peptide (E) and having anti-influenza virus activity. The conjugate or the intermediate compound of the present invention has significant anti-influenza virus activity, and meanwhile, has excellent in vitro/in vivo pharmacokinetic property and safety and has good clinical application prospects.

Abstract: The invention relates to an aerosol-generating system comprising a main unit and a replaceable mouthpiece. The main unit comprises a heating element for heating an aerosol-forming substrate. The mouthpiece comprising an outlet channel. The mouthpiece and the main unit have corresponding structural components with complementary geometrical shapes. When the mouthpiece is connected to the main unit, the corresponding structural components of the mouthpiece and the main unit define an inlet channel. The inlet channel and the outlet channel form an airflow path from an air inlet to an air outlet via the heating element.

Abstract: A needle for a choke valve assembly includes a base portion formed from a first non-superhard material and a tip portion formed from a superhard material. The needle also includes a brazed connection coupling the tip portion to the base portion. The brazed connection includes an insert formed from a second non-superhard material, in which the second non-superhard material is harder than the first non-superhard material and softer than the superhard material. In addition, the brazed connection includes a shim disposed between the insert and the base portion, a first layer of brazing material disposed between the base portion and the shim, and a second layer of brazing material disposed between the shim and the insert.

Abstract: A clamping mechanism, an instrument cassette, and a sterile isolation plate assembly. The clamping mechanism includes a base plate and a pair of clamping assemblies. Each clamping assembly is fixedly connected to an upper surface of the base plate, has an engaging position and a disengaging position, includes a moving member, at least two clamping members, and several elastic members abutting against respective clamping members. The moving member extends in a front-rear direction and is movable between the engaging and disengaging position. The clamping member includes an upper end portion fixedly connected to or abutting against the moving member and a lower end portion of a hook-shaped structure. The clamping assembly moves from the engaging position to the disengaging position under an action of an external force and compress the corresponding elastic member, and moves from the disengaging position to the engaging position under an action of the elastic member.

Abstract: A vehicle-mounted expansion bracket is disclosed, including a mounting rod, configured for being inserted into a trailer hook of a vehicle; a jacking member, rotatably arranged on the mounting rod, where the jacking member is operable in a first working state where the jacking member is rotated relative to the mounting rod to abut against an inner wall of the trailer hook and a second working state where the jacking member is rotated to separate from the inner wall of the trailer hook; and a driving device, arranged on the mounting rod, contacted with the jacking member, and capable of driving the jacking member to rotate and keep in the first working state.

Abstract: Disclosed is a fully immersed energy storage device, which includes a casing and a water pump. An insulation box is mounted inside the casing, and the insulation box is assembled with an assembly plate thereon. A mounting platform is mounted on the assembly plate and assembled with an annular rack. A rotating groove is provided between the mounting platform and the annular rack. Balls are placed in the rotating groove. The mounting platform is assembled with an assembly block, on which a rotating shaft is mounted. One end of the rotating shaft connects to a gear. The other end of the rotating shaft connects to a first assembly rod, to which a second assembly rod is connected. The second assembly rod connects to a fixed block, which is connected to an energy storage box. A motor base is mounted on the casing. A motor is mounted on the motor base.

Abstract: Systems and methods for advertising an Internet Protocol version 4 (IPv4) address of loopback interfaces to participating Open Shortest Path First (OSPF) areas include operating a plurality of interfaces with at least two interfaces being connected to different OSPF areas and having a loopback address; and advertising the loopback address to each of the OSPF areas in a router Link State Advertisement (LSA).

Abstract: A doctor-controlled platform base, comprising a base, synchronous pedal assemblies arranged at bottom of the base, a control pedal assembly and a brake assembly; the control pedal assembly is connected under the base, and is connected to the synchronous pedal assemblies; a walking device is arranged below the base; one end of the brake assembly is hingedly connected to the control pedal assembly, and the other end is connected to the walking device; when at least one synchronous pedal assembly is subjected to an external force, the two synchronous pedal assemblies ascend and descend synchronously, driving the control pedal assembly to ascend and descend in the same direction; when ascending and descending, the control pedal assembly can drive the brake assembly to move to lock or loosen the walking device. The synchronous pedal assemblies can be stabilized at the highest stable point or the lowest stable point.

Abstract: The present application provides a method, terminal device, server, system and storage medium for activating payment functions. The method is applicable to a terminal device. The method includes receiving a first input from a user; generating a payment function activation request in response to the first input, the payment function activation request including a payment function identifier for indicating various payment functions that are instructed to be activated for a target resource card; sending, to a server, the payment function activation request; and receiving an activation reply message sent by the server, the activation reply message comprising a target payment identifier generated by the server according to the payment function identifier, the target payment identifier including payment identifiers of the target resource card under the various payment functions that are instructed to be activated for the target resource card.

Abstract: The present application relates to a silicone oil-based immersion coolant for an electronic component. The silicone oil-based immersion coolant for an electronic component includes a base oil and an additive. The base oil includes a low-viscosity silicone oil. The additive includes a silicone oil diluent and a thermally conductive inorganic filler. The viscosity of the low-viscosity silicone oil is less than or equal to 1000 cSt. The thermally conductive inorganic filler is an insulating filler. Based on the mass of the immersion coolant, a mass percentage content of the base oil is in a range from 70% to 85%, a mass percentage content of the silicone oil diluent is in a range from 10% to 20%, and a mass percentage content of the thermally conductive inorganic filler is in a range from 5% to 10%.

Abstract: A robotic device including one or more proximity sensing systems coupled to various portions of a robot body. The proximity sensing systems detect a distance of an object about the robot body and the robotic device reacts based on the detected distance. The proximity sensing systems obtain a three-dimensional (3D) profile of the object to determine a category of the object. The distance of the object is detected multiple times in a sequence to determine a movement path of the object.

Abstract: A method of training a model, an electronic device, and a storage medium are provided, which relate to a field of artificial intelligence, and in particular to a field of reinforcement learning, NLP, etc. The method includes: acquiring a dialogue information; obtaining a predicted information based on the dialogue information by using a first intention recognition model, a first recurrent neural network and a first named entity recognition model; obtaining a machine behavior information based on the predicted information by using a first behavior decision model; acquiring a feedback information for the machine behavior; storing at least one of the predicted information, the machine behavior information, or the feedback information as training data in a database; and performing a model optimization training online based on the training data by using a reinforcement learning algorithm, in response to an amount of the training data reaching a preset data amount.

Abstract: Disclosed herein is an instrument and associated methods for a fully automated bench-top NULISA platform, comprising an X-Y-Z-gantry, a microtiter plate stage, an incubator, a quantitative PCR module, a decontamination cleaner for microtiter plates, a microtiter plate sealer, a magnetic probe and comb assembly for sample mixing and magnetic bead extraction, a storage unit for reagents and supplies, and a controller.

Abstract: An intelligent dredging system for a high-piled wharf and a control method thereof are provided, and the system includes an intelligent monitoring-decision control subsystem and a decentralized high-pressure water disturbance subsystem. The intelligent monitoring-decision control subsystem is composed of a high-precision pile-foundation sediment siltation warning device, a tidal monitoring device and a control terminal. The decentralized high-pressure water disturbance subsystem is composed of a water spraying device, a cable and a multi-loop power distribution device.

Abstract: A three-piece modular aerosol-generating device, including: a mouthpiece including one first connection element at a distal end of the mouthpiece; a functional component including an air inlet and a cavity to receive a consumable; and a main body, the component being arranged between the mouthpiece and the main body and further including one second connection element at a proximal end and one first connection element arranged at a distal end, the main body including one second connection element arranged at a proximal end of the main body, the first and the second connection elements being connectable to each other and providing mechanical, electrical, and hermetic coupling, the first connection elements including an annular recess and the second connection elements including a tubular protrusion, or vice versa, the annular recess being to receive the tubular protrusion, and the annular recess and the tubular protrusion having matching shapes.

Abstract: An ATR kinase inhibitor as shown in formula I, and a preparation method therefor and the use thereof.

Abstract: The disclosure provides a method and apparatus for processing information, an electronic device and a storage medium. The method for processing information includes: determining a first field in a first table in response to a first operation event, where the first field corresponds to one or more first cells, and the one or more first cells have links recorded therein; determining a second field in the first table in response to a second operation event, where the second field corresponds to one or more second cells; and obtaining, in response to a third operation event, a target file pointed to by a link in a first cell corresponding to the first field, and displaying the target file in a second cell corresponding to the first cell.

Abstract: The patent application discloses a degradable thermoset composite. The composite comprises a reaction product of an epoxy resin, a cross-linker, a catalyst. The epoxy resin mixture may comprise at least one cycloaliphatic epoxide. The reaction product may have a glass transition temperature greater than or equal to 140° C. as measured by DMA.

Abstract: The invention relates to an aerosol-generating system comprising an aerosol-generating device (16) and a consumable (10) for the aerosol-generating device. The aerosol-generating device may comprise a cavity (18) for receiving the consumable and a first heating element (20, 22) arranged to at least partly heat the consumable when the consumable is received in the cavity. The aerosol-generating device may further comprise an airflow channel (14). The airflow channel may be arranged to direct air through the device and into the cavity. The consumable may comprise a tubular wall (12). The tubular wall may extend from a distal opening of the consumable to an opposite proximal opening of the consumable. The consumable may be arranged, when the consumable is received in the cavity, such that the air flowing into the cavity from the airflow channel flows into the distal opening of the consumable.

Abstract: The present application provides a method, terminal device, server, system and storage medium for activating payment functions. The method is applicable to a terminal device. The method includes receiving a first input from a user; generating a payment function activation request in response to the first input, the payment function activation request including a payment function identifier for indicating various payment functions that are instructed to be activated for a target resource card; sending, to a server, the payment function activation request; and receiving an activation reply message sent by the server, the activation reply message comprising a target payment identifier generated by the server according to the payment function identifier, the target payment identifier including payment identifiers of the target resource card under the various payment functions that are instructed to be activated for the target resource card.