Abstract: Provided are a modified immunoglobulin single variable domain, and a protein or polypeptide comprising same. The modified immunoglobulin single variable domain has reduced binding to a pre-anti-drug antibody. Specifically, the C terminal of the immunoglobulin single variable domain comprises amino acid modification. The present invention further relates to an immunoglobulin single variable domain, the pharmaceutical use of a protein or polypeptide comprising same, a pharmaceutical composition, an encoding nucleic acid, and a preparation method.

Abstract: A computer-implemented method and apparatus are provided for training a safety driver associated with an autonomous vehicle (AV) operating in an autonomous driving mode. The computer-implemented method includes receiving a selection of one or more vehicle operation faults that are configured to impact operation of one or more vehicle systems of the AV. The computer-implemented method also includes injecting the one or more vehicle operation faults into one or more vehicle systems of the AV and detecting one or more driver responses executed by the safety driver in response to the one or more vehicle operation faults. The computer-implemented method further includes determining a reaction time associated with the one or more driver responses. The reaction time is a measure of time it takes the safety driver to respond to the one or more vehicle operation faults.

Abstract: An ATR kinase inhibitor as shown in formula I, and a preparation method therefor and the use thereof.

Abstract: A driving circuit, a driving method and a display device are provided. The driving circuit includes a first control node control circuit, a second control node control circuit, a first node control circuit and a second node control circuit, wherein, the first control node control circuit is configured to control a potential of the first control node; the second control node control circuit is configured to control a potential of the second control node; the first node control circuit is configured to control a potential of the first node; the second node control circuit is electrically connected to the second control node, a first clock signal terminal and a second node respectively, and is configured to control to connect the first clock signal terminal and the second node under the control of the potential of the second control node.

Abstract: A display substrate and a display device, the display substrate includes a base substrate, a pixel driving circuit layer, a first planarization layer, a first metal layer, a second planarization layer, a plurality of first electrodes and a pixel definition layer; the pixel driving circuit layer includes a plurality of pixel driving circuits, the first planarization layer includes a plurality of first vias respectively exposing output terminals of the pixel driving circuits, the first metal layer includes a plurality of data lines extending in a first direction, the pixel definition layer includes a plurality of first definition walls extending in the first direction and a plurality of second definition walls extending in a second direction, and an orthographic projection of at least part of the data lines on the base substrate respectively overlaps with orthographic projections of the plurality of first definition walls on the base substrate.

Abstract: A hydraulic circuit for opening and closing a mould of an injection moulding machine, and an injection moulding machine system includes an operating oil cylinder and a proportional valve; by means of adjusting the proportional valve to different operating states, the operating oil cylinder can be controlled to execute different actions, so as to control mould opening, mould closing and mould differential closing of the injection moulding machine. By means of a differential proportional valve with a flow regeneration function, the present invention can effectively increase control precision in a mould opening and closing process, reduce energy consumption and the number of parts of a system, and save on space taken up by the system, with complete functions of mould opening and closing also being realizable.

Abstract: Methods and systems for provisioning resources includes classifying a request for a virtual server instance (VSI) according to resources specified in the request. Dependent resources that the VSI will use are predicted based on the specified resources. A provisioning plan is generated, including timing and configuration information, based on the specified resources and the dependent resources. Resources for the VSI are provisioned according to the provisioning plan, including allocating hardware resources on a computing system.

Abstract: A hand tool includes a first jaw, a first handle fixed to the first jaw, a second jaw, and a second handle pivotally coupled to the second jaw, a link member, and an adjustment member. The adjustment member is operable to axially move a first end of the link member to vary a distance between the first and second jaws. The adjustment member includes an engagement surface engageable with the first end of the link member, a shank in threaded engagement with a bore in the first handle, and a flange extending from the shank opposite the engagement portion. The flange includes a first side, a second side opposite the first side, and an elongate opening extending through the first and second sides.

Abstract: The present disclosure discloses a pixel circuit and a display panel. The pixel circuit comprises a second wire, a first light-emitting control unit, a driving unit, and a compensation unit. A control terminal of the first light-emitting control unit and a control terminal of the compensation unit share the second wire, which can save a wire quantity of the pixel circuit, thereby improving display resolution; at the same time, a control terminal of the driving unit is only equipped with the compensation unit, which reduces a leakage path of the control terminal of the driving unit.

Abstract: Disclosed in the present disclosure is a method for processing remote sensing images by fusing elevation information.

Abstract: Cold-sprayed aluminum capacitors on lead frame metal foils are provided for applications in 3D power package integration. This additive manufacturing process allows pre-patterned low-temperature processing of aluminum electrodes on metal lead frames, insulated metal substrates or even heat-spreaders and cold-plates. Cold-sprayed capacitors can eliminate several process integration and reliability issues that are associated with traditional discrete surface-assembled capacitors.

Abstract: This application provides a display control method and apparatus, applied to an electronic device. The method includes: in response to a first type of operation of a user, if the electronic device is in a first usage posture of a folded state, displaying first application content in a first display direction through the first display screen, and if the electronic device is in a first usage posture of an unfolded state, displaying the first application content in the first display direction through the second display screen.

Abstract: A safe coding method for trackside train positioning information, including the following steps: compiling line position coding information of a train by using a redundancy coding scheme; identifying a coding string on a trackside signboard by an image collector, and sending the coding string to a vehicle-mounted safety computer after check; after performing multi-channel redundancy safe calculation on the coding string by the vehicle-mounted safety computer, looking up a table in a position database to obtain train position information corresponding to the coding string; and, updating a real position of the train according to the train position information determined by looking up the table.

Abstract: A structure for holding a battery on an automated guided vehicle (AGV) so as to allow easy and convenient battery replacement includes two fixed supports and a bracket. The bracket is connected between the two supports and each support defines a vertical groove and two horizontal grooves. Two sliders at the ends of the bracket are insertable into either horizontal groove. The two sliders can move down along the vertical groove together until the bracket makes contact with the battery and holds it in place. The two sliders can move up along the vertical groove and sideways into the horizontal grooves, thereby unlatching and releasing the battery for rapid replacement. An AGV using the structure is also disclosed.

Abstract: A multi-layer and multi-cavity laminating machine including a multi-layer feeding device, at least two multi-layer laminating devices, and a multi-layer finished product conveying device connected in sequence is provided. The number of multi-layer laminating devices are increased, and the laminating steps are carried out step by step. After completing the first laminating step, the solar cell module can be transported to the next multi-layer laminating device, so that the next solar cell module can be transported to the previous multi-layer laminating device, thereby improving production efficiency. In the same production time, it is possible to increase the production quantity or reduce the production time by producing the same quantity of products.

Abstract: Analog system and method for implementing an iterative neural network based model, the system comprising analog vector-by-matrix multiplication circuitry encoding a matrix of weights of an iterative neural network-based model, and analog nonlinearity circuitry encoding a non-linear function arranged in a feedback loop configured to return the output signals from the nonlinearity circuitry as inputs to the vector-by-matrix multiplication circuitry, wherein the system is configured to output a solution vector of values of the iterative neural network based model on convergence of the system.

Abstract: A downhole electromagnetic logging tool comprises a transmitting system, a magnetic field sensor array and a control module. The transmitting system and the magnetic field sensor array are both connected to the control module. The transmitting system comprises an upper emission coil and a lower emission coil, which are respectively arranged above and below the magnetic field sensor array, for generating magnetic fields of opposite polarities, allowing the magnetic fields to be concentrated at the magnetic field sensor array. A casing generates a secondary magnetic field, which is received by the magnetic field sensor array to complete detection of the casing.

Abstract: An information processing apparatus includes: an information management unit that registers boarding information on users regarding boarding and biometrics information on the users acquired by a check-in procedure of the users in association with each other; and a comparison unit that compares target biometrics information, which is biometrics information acquired in a procedure up to the boarding for one of the users, with registered biometrics information, which is the biometrics information registered by the information management unit, and the comparison unit selects the registered biometrics information to be compared with the target biometrics information based on status regarding the procedure up to the boarding of the user corresponding to the registered biometrics information.

Abstract: A computer-implemented method of training an auxiliary machine learning model to predict a set of new parameters of a primary machine learning model, wherein the primary model is configured to transform from an observed subset of a set of real-world features to a predicted version of the set of real-world features.

Abstract: A computer-implemented method comprising: tuning first, second and third set of parameters of respective neural networks by minimising a loss function, the loss function comprising a sum of: a measure of difference between a distribution of a first plurality of latent vectors and a distribution of a second plurality of latent vectors; and an error determined based on a set of computed vectors, a set of computed mask vectors and ground truth data for the set of data.