Patents by Inventor Chengalrayan Kudithipudi

Chengalrayan Kudithipudi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220267785
    Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: March 1, 2022
    Publication date: August 25, 2022
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Jaemo Yang, Yanxin Shen, Dongmei Xu, Ujwala Warek, James Strickland, Jesse Frederick
  • Publication number: 20220243215
    Abstract: Composition and methods for the modification of the secondary metabolic functions of glandular trichomes in plants, such as tobacco or Cannabis, that control the formation of terpenes that impart specific flavor and aroma characteristics to the plant leaves are provided. Enhanced terpene production and composition are achieved through targeted modification in the biochemical synthesis pathways for menthol and cis-abienol. This application provides novel nucleotide sequences encoding the enzymology for production of these terpenes in tobacco and Cannabis application to their use plants.
    Type: Application
    Filed: February 2, 2022
    Publication date: August 4, 2022
    Inventors: Chengalrayan KUDITHIPUDI, Yanxin SHEN, Dongmei XU, Michael Paul TIMKO, Roel RABARA
  • Publication number: 20220243216
    Abstract: The present disclosure relates to compositions and methods related to modification of trichome density and transport of metabolite and their uses in plants, including tobacco and cannabis. The provided transcription factors enable the increase in trichome density in plants.
    Type: Application
    Filed: February 2, 2022
    Publication date: August 4, 2022
    Inventors: Chengalrayan KUDITHIPUDI, Yanxin SHEN, Dongmei XU, Michael Paul TIMKO, Roel RABARA
  • Publication number: 20220243214
    Abstract: The present disclosure relates to compositions and methods related to tissue-specific promoters and their uses in plants, including tobacco and cannabis. The provided trichome-specific promoters enable the expression of heterologous polynucleotides in trichome tissues.
    Type: Application
    Filed: February 2, 2022
    Publication date: August 4, 2022
    Inventors: Chengalrayan Kudithipudi, Yaxin Shen, Dongmei Xu, Michael Paul Timko, Roeol Rabara
  • Patent number: 11384361
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: July 12, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dong Qi, Yanxin Shen, Ujwala Warek, James A. Strickland, Dongmei Xu
  • Patent number: 11377665
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs. Also provided are methods and compositions for increasing the expression of chorismate mutase and other transcription factors involved in anthocyanin biosynthesis.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: July 5, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dongmei Xu, James Strickland, Yanxin Shen
  • Publication number: 20220204981
    Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: January 7, 2022
    Publication date: June 30, 2022
    Applicant: Altria Client Services LLC
    Inventors: Marcos Fernando de GODOY LUSSO, James A. STRICKLAND, Jesse FREDERICK, Dongmei XU, Chengalrayan KUDITHIPUDI
  • Publication number: 20220192250
    Abstract: This disclosure provides tobacco plants containing a PMT RNAi and tobacco plants having a mutation in PMT, and methods of making and using such plants.
    Type: Application
    Filed: March 9, 2022
    Publication date: June 23, 2022
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan Kudithipudi, Alec J. Hayes, Marcos Fernando de Godoy Lusso, Jerry Whit Morris
  • Publication number: 20220142228
    Abstract: This disclosure provides a number of sequences involved in nitrogen utilization, methods of using such sequences, tobacco plants carrying modifications to such sequences, tobacco plants transgenic for such sequences, and tobacco products made from such plants.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 12, 2022
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Jesse FREDERICK, Chengalrayan KUDITHIPUDI, Dongmei XU
  • Patent number: 11304440
    Abstract: This disclosure provides tobacco plants containing a PMT RNAi and tobacco plants having a mutation in PMT, and methods of making and using such plants.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: April 19, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Alec J. Hayes, Marcos Fernando de Godoy Lusso, Jerry Whit Morris
  • Patent number: 11299743
    Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: April 12, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Alec J. Hayes, Robert Frank Hart, III, Yanxin Shen, Jesse Frederick, Dongmei Xu
  • Patent number: 11293030
    Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: April 5, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Jaemo Yang, Yanxin Shen, Dongmei Xu, Ujwala Warek, James Strickland, Jesse Frederick
  • Publication number: 20220098604
    Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
    Type: Application
    Filed: December 15, 2021
    Publication date: March 31, 2022
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Yanxin SHEN, Dongmei XU, Jesse FREDERICK, Jaemo YANG
  • Patent number: 11266174
    Abstract: This disclosure provides a number of sequences involved in nitrogen utilization, methods of using such sequences, tobacco plants carrying modifications to such sequences, tobacco plants transgenic for such sequences, and tobacco products made from such plants.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 8, 2022
    Assignee: Altria Client Services LLC
    Inventors: Jesse Frederick, Chengalrayan Kudithipudi, Dongmei Xu
  • Patent number: 11236349
    Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: February 1, 2022
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Yanxin Shen, Dongmei Xu, Jesse Frederick, Jaemo Yang
  • Patent number: 11220695
    Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: January 11, 2022
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Marcos Fernando de Godoy Lusso, James A Strickland, Jesse Frederick, Dongmei Xu, Chengalrayan Kudithipudi
  • Publication number: 20210275980
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: April 2, 2020
    Publication date: September 9, 2021
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James Strickland
  • Patent number: 11104912
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: August 31, 2021
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei Xu, Jesse Frederick, Chengalrayan Kudithipudi, Yanxin Shen, James Strickland, Jaemo Yang
  • Patent number: 11034969
    Abstract: The present specification provides for, and includes recombinant polynucleotides that encode plant-native, callus-preferred promoters operably linked to a coding region for a visual marker gene. The present specification also provides for, and includes plants comprising the recombinant nucleotides, methods to select callus comprising the disclosed recombinant nucleotides, and methods to create plants comprising the recombinant nucleotides.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: June 15, 2021
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Raja Payyavula, Dong Qi, Yanxin Shen
  • Publication number: 20210100213
    Abstract: The present disclosure provides metabolic signatures and genetic markers for tracking enhanced nitrogen utilization efficiency phenotypes in tobacco plants and for introgressing enhanced nitrogen utilization efficiency phenotypes into tobacco plants. The disclosure also provides tobacco plants comprising enhanced nitrogen utilization efficiency and methods to the creation of tobacco plants comprising enhanced nitrogen utilization efficiency. The disclosure also provides recombinant polynucleotides and polypeptides for enhancing nitrogen utilization efficiency in modified tobacco plants and tobacco plants comprising the provided recombinant polynucleotides and polypeptides.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 8, 2021
    Applicant: Altria Client Services LLC
    Inventors: Jesse Frederick, Chengalrayan Kudithipudi, Dongmei Xu