Patents by Inventor Chenghua Liu

Chenghua Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160283558
    Abstract: Embodiments of the present invention provide a column-oriented database processing method, where a column-oriented database includes a marker column and more than one data column, the data column is used to store specific data in a column store manner, a value of a marker bit of each row in the marker column is used to indicate validity of data that is located in a same row as the marker bit, and the method includes: receiving a query request sent by an application program, where the query request contains a query condition; querying the more than one data column according to the marker column and the query condition to obtain a query result that meets both the query condition and a requirement that a marker bit of the query result in the marker column is valid; and sending the query result to the application program.
    Type: Application
    Filed: June 6, 2016
    Publication date: September 29, 2016
    Applicant: HUAWEI TECHNOLOGIES CO.,LTD.
    Inventors: Jimin Wu, Qing Zhang, Chenghua Liu, Yong Deng
  • Publication number: 20110268724
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 3, 2011
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Patent number: 7981413
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: July 19, 2011
    Assignee: ARCA Biopharma Inc.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Patent number: 7678889
    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and noncancerous disease states in ovarian, identifying ovarian tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovarian tissue for treatment and research.
    Type: Grant
    Filed: August 6, 2003
    Date of Patent: March 16, 2010
    Assignee: diaDexus, Inc.
    Inventors: Roberto A. Macina, Susana Salceda, Chenghua Liu, Yongming Sun, Leah R. Turner
  • Publication number: 20090042199
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: February 12, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Publication number: 20090023659
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: August 20, 2008
    Publication date: January 22, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Publication number: 20080260747
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 23, 2008
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Patent number: 7425610
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polyeptides.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: September 16, 2008
    Assignee: Nuvelo, Inc.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Patent number: 7361475
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: April 22, 2008
    Assignee: diaDexus, Inc.
    Inventors: Yongming Sun, Herve E. Recipon, Malavika G. Ghosh, Chenghua Liu
  • Patent number: 7317099
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: December 23, 2000
    Date of Patent: January 8, 2008
    Assignee: Kirin Pharma Kabushiki Kaisha
    Inventors: Ivan Labat, Y. Tom Tang, Radoje T. Drmanac, Chenghua Liu, Juhi Lee, Nancy K. Mize, John Childs, Cheng-Chi Chao
  • Patent number: 7208267
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: April 24, 2007
    Assignee: Diadexus, Inc.
    Inventors: Susana Salceda, Roberto Macina, Herve E. Recipon, Jason Pluta, Yongming Sun, Chenghua Liu
  • Publication number: 20070060743
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: May 16, 2001
    Publication date: March 15, 2007
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje Drmanac
  • Publication number: 20070049743
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 13, 2002
    Publication date: March 1, 2007
    Inventors: Y. Tang, Chenghua Liu, Vinod Asundi, Rui-Hung Chen, Feiyan Ren, Jian-Rui Wang, Tom Wehrman, Aidong Xue, Yonghong Yang, Jie Zhang, Qing Zhao, Ping Zhou, Radoje Drmanac, Ryle Goodrich
  • Publication number: 20070042392
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: August 31, 2005
    Publication date: February 22, 2007
    Applicant: NUVELO, Inc.
    Inventors: Y. Tang, Chenghua Liu, Vinod Asundi, Rui-hong Chen, Yunqing Ma, Feiyan Ren, Jian-Rui Wang, Thomas Wehrman, Chongjun Xu, Aidong Xue, Yonghong Yang, Jie Zhang, Qing Zhao, Ping Zhou, Radoje Drmanac, Yi-Cheng Cao, Dunrui Wang, Zhi Wang, Ryle Goodrich
  • Patent number: 7109030
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: September 19, 2006
    Assignee: Nuvelo, Inc.
    Inventors: Douglas A. Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tom Tang, Radoje T. Drmanac
  • Publication number: 20060199180
    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and noncancerous disease states in ovarian, identifying ovarian tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovarian tissue for treatment and research.
    Type: Application
    Filed: August 6, 2003
    Publication date: September 7, 2006
    Inventors: Roberto Macina, Susana Salceda, Chenghua Liu, Yongming Sun, Leah Turner
  • Publication number: 20060073514
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
    Type: Application
    Filed: August 12, 2002
    Publication date: April 6, 2006
    Inventors: Douglas Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tang, Radoje Drmanac
  • Publication number: 20060074044
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof the correspond to a novel human secreted stem cell growth factor-like polypeptide. These polypeptides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invertion include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 18, 2005
    Publication date: April 6, 2006
    Applicant: Nuvelo
    Inventors: Ivan Labat, Y. Tang, Radoje Drmanac, Chenghua Liu, Juhi Lee, Nancy Mize, John Childs, Cheng-Chi Chao
  • Publication number: 20060052591
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleoddes and mutants or variants thereof that correspond to a novel human secreted CEA-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from rectum (Hyseq clone identification numbers 15456780 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CEA-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: January 25, 2001
    Publication date: March 9, 2006
    Inventors: Bryan Boyle, Chiaoyun Kuo, Matthew Arterburn, Y Tang, Chenghua Liu, Radoje Drmanac
  • Publication number: 20060051759
    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.
    Type: Application
    Filed: June 16, 2003
    Publication date: March 9, 2006
    Inventors: Susana Salceda, Roberto Macina, Leah Turner, Yongming Sun, Chenghua Liu