Patents by Inventor Chenghua Liu

Chenghua Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel nucleic acids and polypeptides
    Publication number: 20040137434
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 3, 2002
    Publication date: July 15, 2004
    Inventors: Y. Tom Tang, Ping Zhou, Ryle Goodrich, Chenghua Liu, Vinod Asundi, Feiyan Ren, Jie Zhang, Qing A. Zhao, Aidong Xue, Yonghong Yang, Tom Wehrman, Radoje T. Drmanac
  • Methods and materials relating to soluble transforming growth factor alpha-like polypeptides and polynucleotides
    Publication number: 20040132022
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted TGF alpha-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human adult kidney (Hyseq clone identification number 16441036). Other aspects of the invention include vectors containing processes for producing novel human secreted TGF alpha-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 1, 2004
    Publication date: July 8, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, Servando Palencia, Y Tom Tang, Chenghua Liu, Radoje T. Drmanac, Ivan Labat, Birgit Stache-Crain, Kody Nguyen, Veronica E. Garcia
  • Methods and materials relating to semaphorin-like polypeptides and polynucleotides
    Publication number: 20040121948
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: October 3, 2003
    Publication date: June 24, 2004
    Inventors: Bryan J Boyle, Nancy K. Mize, Matthew C. Arterburn, George Yeung, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
    Publication number: 20040116683
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted neurotrimin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human thalamus (Hyseq clone identification number 10468562). Other aspects of the invention include vectors containing processes for producing novel human secreted neurotrimin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 29, 2003
    Publication date: June 17, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, George Yeung, Y. Tom Tang, Ping Zhou, Chenghua Liu, Radoje T. Drmanac, Vinod Asundi, Menq-Yun Wang, Lichuan Chen, Yea-Huey Yang
  • Methods and materials relating to hematopoietic cytokine-like polypeptides and polynucleotides
    Publication number: 20040106116
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted HC-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from thymus (Hyseq clone identification numbers 15097076 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted HC-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: July 15, 2003
    Publication date: June 3, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, Servando Palencia, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Nucleic acids and polypeptides
    Patent number: 6743619
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: June 1, 2004
    Assignee: Nuvelo
    Inventors: Y. Tom Tang, Ping Zhou, Ryle Goodrich, Chenghua Liu, Vinod Asundi, Feiyan Ren, Jie Zhang, Qing A. Zhao, Yonghong Yang, Aidong J. Xue, Tom Wehrman, Jian-Rui Wang, Dunrui Wang, Radoje T. Drmanac
  • Methods and materials relating to leucine-rich repeat protein-like (lrr protein-like) polypeptides and polynucleotides
    Publication number: 20040072173
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted LRR protein-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from thymus (Hyseq clone identification numbers 16395938 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted LRR protein-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 15, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Mattew C. Arterburn, George Yeung, Y.Tom Tang, Chenghua Liu, Radoje T. Drmanac, Menq-Yun Wang, Linchuan Chen, Yea-Huey Yang
  • Method and materials relating to g protein-coupled receptor-like polypeptides and polynucleotides
    Publication number: 20040068097
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted GPCR-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human leukocyte mRNA (GIBCO Laboratories) (SEQ ID NO: 1), from human adult liver mRNA (GIBCO) (SEQ ID NO: 10); from human adult kidney mRNA (GIBCO) (SEQ ID NO: 17); from human adult brain mRNA (GIBCO) (SEQ ID NO: 26) and from human adult kidney mRNA (Invitrogen) (SEQ ID NO: 33). Other aspects of the invention include vectors containing processes for producing novel human secreted GPCR-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 8, 2004
    Inventors: Victoria Yamazaki, Y. Tom Tang, Chenghua Liu, Ping Zhou, Dunrui Wang, Jie Zhang, Feiyan Ren, Vinod Asundi, Radoje T. Drmanac
  • Compositions and methods relating to ovary specific genes and proteins
    Publication number: 20040058319
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic ovary cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and non-cancerous disease states in ovary tissue, identifying ovary tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovary tissue for treatment and research.
    Type: Application
    Filed: November 20, 2001
    Publication date: March 25, 2004
    Inventors: Susana Salceda, Roberto Macina, Herve E. Recipon, Robert Cafferkey, Yongming Sun, Chenghua Liu
  • Egf motif protein, egfl6 materials and methods
    Publication number: 20040059098
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides of the invention is useful for detecting cancers.
    Type: Application
    Filed: October 2, 2003
    Publication date: March 25, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, John E. Ford, Victoria Yamazaki, George Yeung, Jie Zhang, Ping Zhou, Radoje T. Drmanac, Hua Zhou
  • Novel nucleic acids and polypeptides
    Publication number: 20040053248
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 24, 2003
    Publication date: March 18, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040053245
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 24, 2003
    Publication date: March 18, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040044181
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: July 15, 2003
    Publication date: March 4, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Tom Wehrman, Feiyan Ren, Ping Zhou, Qing A. Zhao, Radoje T. Drmanac, Jie Zhang, Aidong Xue, Jian-Rui Wang, Dunrui Wang
  • Novel nucleic acids and polypeptides
    Publication number: 20040034208
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 19, 2003
    Publication date: February 19, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Chongjun Xu, Tom Wehrman, Feiyan Ren, Yunging Ma, Ping Zhou, Qing A. Zhao, Yonghong Yang, Radoje T. Drmanac, Jie Zhang, Rui-hong Chen, Aidong Xue, Jian-Rui Wang
  • Novel nucleic acids and polypeptides
    Publication number: 20030235883
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: July 15, 2003
    Publication date: December 25, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Yonghong Yang, Radoje T. Drmanac, Jie Zhang, Rui-hong Chen, Aidong Xue, Vinod Asundi, Chongjun Xu, Feiyan Ren, Ping Zhou, Qing A. Zhao, Jian-Rui Wang, Ryle Goodrich, Dunrui Wang
  • Novel nucleic acids and polypeptides
    Publication number: 20030232054
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 8, 2002
    Publication date: December 18, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Rui-Hong Chen, Xiaohong B. Qian, Zhi Wei Wang, Tom Wehrman, Jie Zhang, Ping Zhou, Yi-Cheng Cao, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20030228584
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof
    Type: Application
    Filed: November 8, 2002
    Publication date: December 11, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Rui-Hong Chen, Yunqing Ma, Feiyan Ren, Jian-Rui Wang, Tom Wehrman, Chongjun Xu, Aidong J. Xue, Yonghong Yang, Jie Zhang, Qing A. Zhao, Ping Zhou, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20030219743
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 2, 2002
    Publication date: November 27, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Feiyan Ren, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20030219745
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 11, 2002
    Publication date: November 27, 2003
    Inventors: Y. Tom Tang, Ryle Goodrich, Chenghua Liu, Feiyan Ren, Dunrui Wang, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20030219744
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 4, 2002
    Publication date: November 27, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Jie Zhang, Radoje T. Drmanac