Patents by Inventor Chenghua Liu

Chenghua Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel nucleic acids and polypeptides
    Publication number: 20030087370
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: May 15, 2002
    Publication date: May 8, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Ping Zhou, Vinod Asundi, Jie Zhang, Jian-Rui Wang, Aidong J. Xue, Chongjun Xu, Radoje T. Drmanac
  • Compositions and methods relating to breast specific genes and proteins
    Publication number: 20030077604
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.
    Type: Application
    Filed: October 29, 2001
    Publication date: April 24, 2003
    Inventors: Yongming Sun, Herve E. Recipon, Susana Salceda, Chenghua Liu, Leah R. Turner
  • Novel nucleic acids and polypeptides
    Publication number: 20030073099
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: March 25, 2002
    Publication date: April 17, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Ping Zhou, Vinod Asundi, Feiyan Ren, Qing A. Zhao, Aidong J. Xue, Jie Zhang, Tom Wehrman, Jian-Rui Wang, Radoje T. Drmanac
  • Compositions and methods relating to lung specific genes and proteins
    Publication number: 20030068624
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
    Type: Application
    Filed: October 26, 2001
    Publication date: April 10, 2003
    Inventors: Herve E. Recipon, Yongming Sun, Sei-Yu Chen, Chenghua Liu, Leah R. Turner
  • Compositions and methods relating to prostate specific genes and proteins
    Publication number: 20030064377
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention.
    Type: Application
    Filed: November 6, 2001
    Publication date: April 3, 2003
    Inventors: Yongming Sun, Herve E. Recipon, Sei-Yu Chen, Chenghua Liu
  • Compositions and methods relating to lung specific genes and proteins
    Publication number: 20030064378
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
    Type: Application
    Filed: October 26, 2001
    Publication date: April 3, 2003
    Inventors: Herve E. Recipon, Yongming Sun, Sei-Yu Chen, Chenghua Liu, Leah R. Turner
  • Compositions and methods relating to ovary specific genes and proteins
    Publication number: 20030059784
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic ovary cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and non-cancerous disease states in ovary tissue, identifying ovary tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovary tissue for treatment and research.
    Type: Application
    Filed: November 7, 2001
    Publication date: March 27, 2003
    Inventors: Yongming Sun, Herve E. Recipon, Susana Salceda, Chenghua Liu
  • Compositions and methods relating to breast specific genes and proteins
    Publication number: 20030044815
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.
    Type: Application
    Filed: February 14, 2002
    Publication date: March 6, 2003
    Inventors: Susana Salceda, Roberto Macina, Ping Hu, Herve E. Recipon, Kalpana Karra, Robert Cafferkey, Yongming Sun, Chenghua Liu
  • Compositions and methods relating to prostate specific genes and proteins
    Publication number: 20030039983
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention.
    Type: Application
    Filed: November 1, 2001
    Publication date: February 27, 2003
    Inventors: Yongming Sun, Herve E. Recipon, Sei-Yu Chen, Chenghua Liu
  • Compositions and methods relating to prostate specific genes and proteins
    Publication number: 20030039986
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention.
    Type: Application
    Filed: November 5, 2001
    Publication date: February 27, 2003
    Inventors: Yongming Sun, Herve E. Recipon, Sei-Yu Chen, Chenghua Liu
  • Stem cell maintenance factor materials and methods
    Publication number: 20030027255
    Abstract: The present invention provides novel nucleic acids encoding human stem cell maintenance factors, the novel polypeptides encoded by these nucleic acids and uses of these and related products.
    Type: Application
    Filed: October 26, 2001
    Publication date: February 6, 2003
    Inventors: Dennis G. Ballinger, Radoje T. Drmanac, Ivan Labat, Birgit Stache-Crain, Mark C. Dickson, Lee W. Jones, Aidong Xue, Y. Tom Tang, Chenghua Liu, Vinod Asundi
  • Novel nucleic acids and polypeptides
    Publication number: 20030022329
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 17, 2002
    Publication date: January 30, 2003
    Inventors: Y. Tom Tang, Chenghua Liu, Ping Zhou, Vinod Asundi, Feiyan Ren, Qing A. Zhao, Aidong J. Xue, Jie Zhang, Tom Wehrman, Jian-Rui Wang, Radoje T. Drmanac
  • Compositions and methods relating to colon specific genes and proteins
    Publication number: 20030022188
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
    Type: Application
    Filed: November 20, 2001
    Publication date: January 30, 2003
    Inventors: Roberto A. Macina, Herve E. Recipon, Jason Pluta, Malavika Ghosh, Yongming Sun, Chenghua Liu
  • Novel nucleic acids and polypeptides
    Publication number: 20020197679
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: March 13, 2002
    Publication date: December 26, 2002
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, Chongjun Xu, Ping Zhou, Yunqing Ma, Jian-Rui Wang, Qing A. Zhao, Feiyan Ren, Rui-Hong Chen, Dunrui Wang, Zhiwei Wang, Tom Wehrman, Jie Zhang, Xiaohong B. Qian, Radoje T. Drmanac
  • Compositions and methods relating to colon specific genes and proteins
    Publication number: 20020192220
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
    Type: Application
    Filed: October 31, 2001
    Publication date: December 19, 2002
    Inventors: Yongming Sun, Herve E. Recipon, Malavika G. Ghosh, Chenghua Liu
  • Compositions and methods relating to colon specific genes and proteins
    Publication number: 20020192666
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
    Type: Application
    Filed: October 31, 2001
    Publication date: December 19, 2002
    Inventors: Yongming Sun, Herve E. Recipon, Malavika G. Ghosh, Chenghua Liu
  • Compositions and methods relating to lung specific genes and proteins
    Publication number: 20020183500
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
    Type: Application
    Filed: November 20, 2001
    Publication date: December 5, 2002
    Inventors: Roberto Macina, Herve A. Recipon, Sei-Yu Chen, Yongming Sun, Chenghua Liu
  • Compositions and methods relating to breast specific genes and proteins
    Publication number: 20020177696
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.
    Type: Application
    Filed: October 30, 2001
    Publication date: November 28, 2002
    Inventors: Yongming Sun, Herve E. Recipon, Susana Salceda, Chenghua Liu, Leah R. Turner
  • Compositions and methods relating to prostate specific genes and proteins
    Publication number: 20020177140
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention.
    Type: Application
    Filed: November 20, 2001
    Publication date: November 28, 2002
    Inventors: Susana Salceda, Roberto A. Macina, Herve E. Recipon, Robert Cafferkey, Shujath Ali, Yongming Sun, Chenghua Liu
  • Compositions and methods relating to lung specific genes and proteins
    Publication number: 20020172959
    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
    Type: Application
    Filed: October 25, 2001
    Publication date: November 21, 2002
    Inventors: Herve E. Recipon, Yongming Sun, Sei-Yu Chen, Chenghua Liu, Leah R. Turner