Patents by Inventor Chi-Hung Huang

Chi-Hung Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8222207
    Abstract: The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: July 17, 2012
    Assignee: Taiwan Advance Bio-Pharm Inc.
    Inventors: Kou-Juey Wu, Chi-Hung Huang
  • Publication number: 20120176598
    Abstract: An apparatus for quantifying residual stress of a birefringent material comprises a light source generating light; a vertical polarizer converting a beam of light into a beam with vertical polarization; a standard material being mounted in front of the vertical polarizer; a horizontal polarizer converting a beam of light into a beam with horizontal polarization; an applied force unit applying different forces to the standard material; a spectrometer being mounted in front of the horizontal polarizer and recording intensity of light passing through the horizontal polarizer and transmittance of the standard material and a processing module being connected to the spectrometer, deriving a stress formula from the applied forces and transmittances of the standard material and obtaining a stress distribution of the birefringent material. A method for quantifying residual stress of a birefringent material is also disclosed.
    Type: Application
    Filed: June 12, 2011
    Publication date: July 12, 2012
    Applicant: National Tsing Hua University
    Inventors: Wei-Chung Wang, Chi-Hung Huang, Yu-Cheng Tseng, Po-Chi Sung
  • Patent number: 8186245
    Abstract: A mechanical device for transmitting a torque so as to generate a multi-degree-of-freedom rotation is provided. The mechanical device is used for clipping specimens during a vacuum sputtering process. The mechanical device includes an immovable frame, a first and a second shafts and a first and a second connecting elements. The immovable frame fastens the mechanical device, and includes a first hole and a first sleeve, which is disposed in the first hole and has a first transmission element. The first shaft is disposed inside the first hole and the first sleeve, and has a second hole. The second shaft is disposed in the second hole, and is perpendicular to the first shaft.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: May 29, 2012
    Assignee: National Applied Research Laboratories
    Inventors: Nien-Tsu Chen, Hung-Yu Peng, Jyh-Shin Chen, Chi-Hung Huang
  • Patent number: 8124377
    Abstract: The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: February 28, 2012
    Assignee: Taiwan Advance Bio-Pharm Inc.
    Inventors: Kou-Juey Wu, Chi-Hung Huang
  • Publication number: 20120015908
    Abstract: A compound of Formula I is disclosed as follows: or a pharmaceutically acceptable salt, prodrug, solvate, or metabolite thereof, wherein R is hydrogen, P(?O)(OH)2, P(?O)(O(C1-C18)alkylene(C6-C20)aryl)2, P(?O)(OH)(OM), P(?O)(OM)2, P?O(O2M), S(?O)(OH)2, S(?O)(O(C1-C18)alkylene(C6-C20)aryl)2, S(?O)(OH)(OM), S(?O)(OM)2; M is a monovalent or divalent metal ion, or alkylammonium ion; W is (C6-C20)aryl, (C6-C20)heteroaryl, (C1-C18)alkyl(C6-C20)aryl, (C1-C18)alkyl(C6-C20)heteroaryl, hydroxy(C6-C20)aryl, hydroxy(C6-C20)heteroaryl, (C1-C18)alkoxy(C6-C20)aryl, (C1-C18)alkoxy(C6-C20)heteroaryl, (C1-C18)alkylenedioxy(C6-C20)aryl, (C1-C18)alkylenedioxy(C6-C20)heteroaryl, halo(C6-C20)aryl, halo(C6-C20)heteroaryl, (C1-C18)alkylamino(C6-C20)aryl, (C1-C18)alkylamino(C6-C20)heteroaryl, (C1-C18)cycloalkylamino(C6-C20)aryl, or (C1-C18)cycloalkylamino(C6-C20)heteroaryl, and their OR8 substutes; R5 is (C1-C18alkoxy, hydrogen, hydroxyl, O—(C1-C18)alkyl(C6-C20)aryl, halo or OR8, or R5 and R6 are (C1-C18)dioxy provided that R7 i
    Type: Application
    Filed: July 13, 2011
    Publication date: January 19, 2012
    Applicant: Efficient Pharma Management Corporate
    Inventors: Sheng-Chu Kuo, Kuo-Hsiung Lee, Li-Jiau Huang, Li-Chen Chou, Tian-Shung Wu, Tzong-Der Way, Jing-Gung Chung, Jai-Sing Yang, Chi-Hung Huang, Meng-Tung Tsai
  • Publication number: 20110235326
    Abstract: The present invention provides an apparatus for controlling a three-dimensional optical field. The apparatus includes a light-emission device and a set of zoom elements. The light-emission device emits a light. The set of zoom elements are disposed in front of the light-emission device, and focus the light from the light-emission device.
    Type: Application
    Filed: March 25, 2011
    Publication date: September 29, 2011
    Applicant: NATIONAL APPLIED RESEARCH LABORATORY
    Inventors: Jerliang Yeh, Ling-Yu Tsai, Min-Wei Hung, Chi-Hung Huang, Yu-Cheng Su
  • Publication number: 20110092450
    Abstract: The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
    Type: Application
    Filed: October 18, 2010
    Publication date: April 21, 2011
    Inventors: Kou-Juey Wu, Chi-Hung Huang
  • Publication number: 20110092412
    Abstract: The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
    Type: Application
    Filed: October 18, 2010
    Publication date: April 21, 2011
    Inventors: KOU-JUEY WU, CHI-HUNG HUANG
  • Publication number: 20110044509
    Abstract: The present invention discloses a bridge structural safety monitoring system and a bridge structural safety monitoring method. The method includes the steps of capturing an image of a monitoring area of a bridge to create a standard image of the bridge operated at normal conditions, capturing images of the monitoring area of the bridge continuously to obtain monitoring images, comparing the standard image with the monitoring image to obtain a displacement correlation coefficient of the monitoring area of the bridge, and transmitting the displacement correlation coefficient to a central console, such that the central console can determine the using condition of the bridge according to the displacement correlation coefficient.
    Type: Application
    Filed: October 2, 2009
    Publication date: February 24, 2011
    Applicant: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Chi-Hung Huang, Wei-Chieh Chiang, Tai-Shan Liao, Chia-Wei Hsu, Jen-Yu Wen, Tzu-Hsuan Wei, Yung-Hsiang Chen
  • Publication number: 20100116203
    Abstract: A mechanical device for transmitting a torque to generate a multi-degree-of-freedom rotation is provided. The mechanical device is used for clipping the object body during a vacuum sputtering process. The effect of homogeneous film coating is achievable by multi-degree-of-freedom rotation of the specimen when performing a surface treatment, particularly for a cylinder specimen.
    Type: Application
    Filed: November 24, 2008
    Publication date: May 13, 2010
    Inventors: Nien-Tsu Chen, Hung-Yu Peng, Jyh-Shin Chen, Chi-Hung Huang
  • Publication number: 20090227496
    Abstract: The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
    Type: Application
    Filed: March 4, 2008
    Publication date: September 10, 2009
    Inventors: Kou-Juey Wu, Chi-Hung Huang
  • Publication number: 20090120251
    Abstract: A machining method for a brittle material is provided. The machining method includes steps of heating the brittle material; providing a concentrated cold source; and spurting the concentrated cold source on a surface of the brittle material along a predetermined cutting path.
    Type: Application
    Filed: May 2, 2008
    Publication date: May 14, 2009
    Inventors: Min-Wei Hung, Wen-Hong Wu, Kuo-Cheng Huang, Chi Hung Huang
  • Publication number: 20090110271
    Abstract: A color recognition device is provided. The color recognition device includes a color image sensor, an image processing system, and a projection device. The color image sensor senses a color image having an image area with a specific color, and generates a first electrical signal corresponding to the color image. The image processing system receives the first electrical signal, modifies the color image, and generates a second electrical signal. The projection device receives the second electrical signal, and projects a modified image corresponding to the second electrical signal.
    Type: Application
    Filed: December 27, 2007
    Publication date: April 30, 2009
    Applicant: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Yu-Chieh Chen, Tai-Shan Liao, Chi-Hung Huang, Chien-Jen Chen
  • Patent number: 7403270
    Abstract: A novel method for whole field thin film stress evaluation is provided. Through the provided method, the whole filed thin film stress distribution for an optical thin film would be developed with a commercial interferometer, so that a whole field evaluation for the crack or peel-off of thin film is hence achievable.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: July 22, 2008
    Assignee: Instrument Technology Research Center, National Applied Laboratories
    Inventors: Chi Hung Huang, Hsien-I You, Mao-Yuan Shih, Chien-Jen Chen
  • Publication number: 20070226724
    Abstract: Methods and apparatuses for firmware execution and provision are provided. A ROM device stores compressed firmware. A decompressor is coupled to the ROM device, extracting the compressed firmware to a first instruction stream comprising at least one absolute address instruction. A post-filter, coupled to the decompressor, filters the first instruction stream to generate a second instruction stream, whereby the absolute address instruction is converted to a relative address instruction. A RAM device, coupled to the post-filter, stores the second instruction stream filtered from the post-filter. A CPU is coupled to the RAM device, executing the second instruction stream stored in the RAM device.
    Type: Application
    Filed: March 24, 2006
    Publication date: September 27, 2007
    Inventor: Chi-Hung Huang
  • Publication number: 20070150323
    Abstract: A method and a system for generating supply chain planning information are provided, which are used to dynamically adjust the control factors of the supply information provided by an original supplier and an original logistics provider, after the first supply chain planning information has been generated through a conventional supply chain planning information system, so as to generate much more supply information to process. Then, the information is processed by a planning engine of the supply chain planning information system to further generate other supply chain planning information among which to select in decision making. Hence, a decision maker can select and find out improved ways to negotiate with suppliers, so as to reduce the total cost and also meet customers' service quality requirements.
    Type: Application
    Filed: June 21, 2006
    Publication date: June 28, 2007
    Inventors: June-Ray Lin, Chi-Hung Huang, Chun-Kai Wang, Chia-Chun Shih
  • Patent number: 6498879
    Abstract: A structure and method are provided to improve stability of a multi-window dense wavelength division multiplexers and to provide polarization-independent multi-window dense wavelength division multiplexers. In one embodiment, the coupler region of a multi-window wavelength division multiplexer (MWDM) is hermetically sealed in a protective casing to prevent moisture from affecting the passband wavelength drifting in the coupler. In one embodiment, the coupler is elastically twisted at the fused fiber portion to reach polarization cancellation. In another embodiment, the coupling region of the coupler is exposed to UV-radiation for passband wavelength adjustment. In yet another embodiment, a passive thermal compensation technique is used to minimize the thermal effect on the passband wavelengths for dense WDM applications. In a further embodiment, the coupler is mounted on the substrate using soft adhesives in conjunction with rigid adhesives, to improve mechanical shock protection.
    Type: Grant
    Filed: March 31, 1999
    Date of Patent: December 24, 2002
    Assignee: Wavesplitter Technologies, Inc.
    Inventors: Chi-hung Huang, Robert I. Huang, Joseph C. Chon
  • Patent number: 6324322
    Abstract: A fused-fiber multi-window wavelength filter (MWF) is constructed with an unbalanced Michelson Interferometer, in which input light passing through the fused coupling region is decoupled and travels along two fibers of different optical path lengths. The two light signals travel to the end of the two fibers, where a highly reflective coating reflects the light back toward the coupling region, where the signals are coupled again and then decoupled after exiting the coupling region. By adjusting the optical path length difference, either by changing the length or refractive index, a signal at a desired wavelength can be obtained at the filter output. The MWF can be combined with other MWFs to form more compact sized multi-window wavelength division multiplexers (MWDMs) and dense WDMs. Passive thermal compensation techniques can be applied to one or both of the reflecting fibers to maintain the desired optical path length difference.
    Type: Grant
    Filed: June 7, 1999
    Date of Patent: November 27, 2001
    Assignee: WaveSplitter Technologies, Inc.
    Inventors: Huali Luo, Chi-Hung Huang, Joseph C. Chon
  • Patent number: 6263128
    Abstract: According to the present invention, a multi-window wavelength division multiplexer (MWDM) is coupled to a correcting filter characterized by a shallow modulation depth and a channel separation smaller than the MWDM. A correcting filter is coupled to an input of the MWDM or to each of the two outputs of the MWDM. By changing the modulation depth and/or channel separation of the correcting filter(s), the spectral response of the filter can be adjusted to produce a more uniform gain (i.e., a “flat-top” spectral response) across wavelengths of passbands within the MWDM. In one embodiment, the correcting filter is an unbalanced Mach-Zehnder interferometer formed with two fused-fiber couplers having non-equal splitting ratios. In other embodiments, the correcting filter is a Fabry-Perot interferometer having a low end-face reflectivity.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: July 17, 2001
    Assignee: WaveSplitter Technologies, Inc.
    Inventor: Chi-Hung Huang
  • Patent number: 6160932
    Abstract: A wavelength division multiplexer (WDM) utilizes cascaded interferometric devices, where the two output branches of interferometric devices in each new stage are each coupled to an additional stage of interferometric devices having the same wavelength separation or channel spacing, which suppresses the sidelobes of the signals from preceding stage of interferometric devices. In one embodiment, the interferometric devices are unbalanced Mach-Zehnder Interferometers.
    Type: Grant
    Filed: February 16, 1999
    Date of Patent: December 12, 2000
    Assignee: WaveSplitter Technologies, Inc.
    Inventors: Chi-hung Huang, Joseph Chon, Sheau Sheng Chen