Abstract: Disclosed is a photo-stimulation method and device with a light mixture. The method includes the following steps: providing a light-emitting diode (LED) illuminant which is a combination of a yellow LED and a red LED; and illuminating a subject by the LED illuminant to promote collagen synthesis, to suppress microbial growth, or to inhibit melanin synthesis, wherein the yellow LED is in an illuminance range from 1,000 to 3,500 lux, the red LED is in an illuminance range from 6,000 to 9,500 lux, and the number ratio of the yellow LED to the red LED is 0.5-2:0.5-2.

Abstract: Disclosed is a photo-stimulation method and device. The method includes the following steps: providing a light-emitting diode (LED) illuminant which is a yellow, red, or blue LED; and illuminating a subject by the LED illuminant to promote collagen synthesis, to suppress microbial growth, or to inhibit melanin synthesis, wherein the yellow LED is in an illuminance range from 1,000 to 3,500 lux, the red LED is in an illuminance range from 6,000 to 9,500 lux, and the blue LED is in an illuminance range from 3,000 to 7,000 lux.

Abstract: Disclosed is a photo-stimulation method employing an agonist agent, and a kit for introducing same. The method includes the following steps: providing a light-emitting diode (LED) illuminant which is a yellow, red, green, blue LED or a mixture of two or more kinds thereof, and an agonist agent which contains 0.5% to 2% calcium ion; and adding the agonist agent to a subject and illuminating the subject by the LED illuminant to promote collagen synthesis, to suppress microbial growth, or to inhibit melanin synthesis, wherein the yellow LED is in an illuminance range from 1,000 to 3,500 lux, the red LED is in an illuminance range from 6,000 to 9,500 lux, the green LED is in an illuminance range from 1000 to 5000 lux, and the blue LED is in an illuminance range from 3,000 to 7,000 lux.

Abstract: A phototherapy patch is disclosed, which includes: an adhesive layer, having a first surface and an opposite second surface; a pharmaceutical drug layer, disposed on the first surface of the adhesive layer; and a spontaneous emission layer, disposed over the pharmaceutical drug layer and capable of emitting therapeutic light by light illumination or a chemical reaction. Accordingly, the phototherapy patch according to the present invention has no power supply disposed therein, and thereby is suitable to be manufactured as a particularly thin and thus inconspicuous device.

Abstract: The present invention relates to a phototherapy device, which is driven by a power supply and includes: a housing, having a top portion, a bottom portion and a handheld portion, where the top portion has a light outlet, the handheld portion connects the top portion and the bottom portion, and the handheld portion has at least one protruding part; a light-transmitting plate, which covers the light outlet; a light-blocking part, formed into a protruding rim along the circumferential direction of the light outlet; an LED module, disposed in the housing and corresponding to the light outlet; and a control module, electrically connected to the power supply and the LED module. Accordingly, the phototherapy device according to the present invention is suitable for handheld use.

Abstract: A method for real-timely monitoring thickness change of a coating film is disclosed. In the method, a coating module having a chamber and a film thickness-monitoring module containing an SPR optical fiber sensor, a light source, a light-receiving detector, and optical fibers are first provided. The optical fibers are used to connect the SPR optical fiber sensor with the light source and the light-receiving detector. The SPR optical fiber sensor has a sensing area and is arranged in the chamber. The light source provides the SPR optical fiber sensor with light. Then, a substrate is put into the chamber. While coating process is performed on the substrate, a film is also formed on the sensing area of the SPR optical fiber sensor. The light-receiving detector receives signals output from the sensing area of the SPR optical fiber sensor and then outputs signals of light-intensity change.

Abstract: A method for real-timely monitoring thickness change of a coating film is disclosed. In the method, a coating module having a chamber and a film thickness-monitoring module containing an SPR optical fiber sensor, a light source, a light-receiving detector, and optical fibers are first provided. The optical fibers are used to connect the SPR optical fiber sensor with the light source and the light-receiving detector. The SPR optical fiber sensor has a sensing area and is arranged in the chamber. The light source provides the SPR optical fiber sensor with light. Then, a substrate is put into the chamber. While coating process is performed on the substrate, a film is also formed on the sensing area of the SPR optical fiber sensor. The light-receiving detector receives signals output from the sensing area of the SPR optical fiber sensor and then outputs signals of light-intensity change.

Abstract: A phototherapy patch is disclosed, which includes: an adhesive layer, having a first surface and an opposite second surface; a pharmaceutical drug layer, disposed on the first surface of the adhesive layer; and a spontaneous emission layer, disposed over the pharmaceutical drug layer and capable of emitting therapeutic light by light illumination or a chemical reaction. Accordingly, the phototherapy patch according to the present invention has no power supply disposed therein, and thereby is suitable to be manufactured as a particularly thin and thus inconspicuous device.

Abstract: An SPR optical fiber sensor and an SPR sensing device using the same are disclosed. The SPR optical fiber sensor includes: an optical fiber substrate having a sensing area; a first metal layer disposed on the sensing area of the fiber substrate; and a second metal layer which is a gold layer and disposed on the first metal layer. In the present invention, two or more layers of different metals are stacked on the sensing area and thus the SPR measurable range can be promoted to improve the sensitivity and chemical stability of the SPR optical fiber sensor.

Abstract: A surface plasmon resonance sensing device that is portable, and having the fiber sensing unit whose resonant wavelength being within the transmission range of a single-mode fiber or a multi-mode fiber, is disclosed. The disclosed sensing device comprises: a light source unit, a fiber sensing unit, an optical sensor, a plurality of fibers, and a computing and displaying unit. The fiber sensing unit includes a trench, a cladding layer, a core layer, a first metallic layer, and a plurality of dielectric thin film layers, wherein the first metallic layer covers the trench, and the plurality of dielectric thin film layers forms on the first metallic layer. The light source provided by the light source unit will become a light signal, after the light passes through the fiber sensing unit. The optical sensor transforms the light signal into a corresponding electric signal, for the usage of the computing and displaying unit.

Abstract: A phototherapy patch is disclosed, which includes: an adhesive layer, having a first surface and an opposite second surface; a pharmaceutical drug layer, disposed on the first surface of the adhesive layer; and a spontaneous emission layer, disposed over the pharmaceutical drug layer and capable of emitting therapeutic light by light illumination or a chemical reaction. Accordingly, the phototherapy patch according to the present invention has no power supply disposed therein, and thereby is suitable to be manufactured as a particularly thin and thus inconspicuous device.

Abstract: A phototherapy device is disclosed, which is driven by a power supply and includes: an LED module, driven by the power supply to emit therapeutic light; and a polarizer, disposed in a direction toward which the therapeutic light is emitted by the LED module. Accordingly, the phototherapy device according to the present invention can use light of low intensity to achieve therapeutic effect and thereby can be designed in a portable form.

Abstract: A method for surface-modifying a sensor device is disclosed, which includes the following steps: providing a sensor device, wherein a surface of the sensor device has a metal film; forming a surface-modification layer having a plurality of carboxyl groups on the metal film of the sensor device by isopropyl alcohol plasma; and forming a poly(acrylic acid) layer on the surface-modification layer, wherein the acrylic acid of the poly(acrylic acid) layer is grafted to the carboxyl of the surface-modification layer. A surface-modified sensor device is also disclosed.

Abstract: A surface plasmon resonance sensing device that is portable, and having the fiber sensing unit whose resonant wavelength being within the transmission range of a single-mode fiber or a multi-mode fiber, is disclosed. The disclosed sensing device comprises: a light source unit, a fiber sensing unit, an optical sensor, a plurality of fibers, and a computing and displaying unit. The fiber sensing unit includes a trench, a cladding layer, a core layer, a first metallic layer, and a plurality of dielectric thin film layers, wherein the first metallic layer covers the trench, and the plurality of dielectric thin film layers forms on the first metallic layer. The light source provided by the light source unit will become a light signal, after the light passes through the fiber sensing unit. The optical sensor transforms the light signal into a corresponding electric signal, for the usage of the computing and displaying unit.

Abstract: A method for real-timely monitoring thickness change of a coating film is disclosed. In the method, a coating module having a chamber and a film thickness-monitoring module containing an SPR optical fiber sensor, a light source, a light-receiving detector, and optical fibers are first provided. The optical fibers are used to connect the SPR optical fiber sensor with the light source and the light-receiving detector. The SPR optical fiber sensor has a sensing area and is arranged in the chamber. The light source provides the SPR optical fiber sensor with light. Then, a substrate is put into the chamber. While coating process is performed on the substrate, a film is also formed on the sensing area of the SPR optical fiber sensor. The light-receiving detector receives signals output from the sensing area of the SPR optical fiber sensor and then outputs signals of light-intensity change.

Abstract: A method for improving an optical sensor is disclosed, which includes the following steps: providing an optical sensor; acid-treating the surface of the optical sensor; forming a thin metal film on the acid-treated surface of the optical sensor; and plasma-modifying the thin metal film on the optical sensor. The aforesaid method is to clean the surface of the optical sensor and then to improve the hydrophilicity thereof by acid treatment. The thin metal film subsequently formed has good flatness and improved adhesion to the optical sensor. Once the optical sensor has the improved hydrophilicity, the plasma modification is performed to further improve optical performance of the optical sensor.

Abstract: A microfluidic detection device is disclosed, which includes a porous membrane, a wicking pad, and an optical sensor. The porous membrane has a first end and an opposite second end, and the first end has a sample-loading area for receiving sample molecules. The wicking pad is connected with the second end of the porous membrane to move the sample molecules from the sample-loading area of the porous membrane to the second end thereof. The optical sensor has a detection zone which faces the porous membrane for sensing the sample molecules. Also, a method for detecting molecules is disclosed, which uses the aforesaid device. The method and the device can achieve the purpose of real-time detection and fast-screening for molecules.

Abstract: The present invention relates to a method for biomolecule immobilization, comprising: providing a substrate; forming a surface modification layer of carboxy groups on one surface of the substrate, wherein the process for forming the surface modification layer comprises plasma surface modification; and providing pluralities of biomolecules and bonding the biomolecules with the surface modification layer. Accordingly, the method for biomolecule immobilization of the present invention can reduce manufacturing time and enhance the stability of manufacture. In addition, the method can be employed in a biosensor to efficiently enhance sensitivity of the biosensor.

Abstract: A Surface Plasmon Resonance (SPR) fiber sensor is disclosed, which comprises an optical fiber member and a plurality of optical fiber sensing units. Each of the plurality of the optical fiber sensing units comprises a cladding layer, a core layer, and a groove, and the plurality of the optical fiber sensing units is arranged into a cascade form matrix. In each of the optical fiber sensing units, the cladding layer is located at the periphery of the core layer, and the maximum depth of the groove is larger than the thickness of the cladding layer. An SPR sensing apparatus is also disclosed, which includes a light source, an optical signal detector, a plurality of fibers, and a plurality optical fiber sensing units. Besides, the optical fiber sensing units, the light source, and the optical signal detector are connected with each other through the plurality of fibers.

Abstract: A backlight module including a light source, a light guide plate and a prism sheet is provided. The light source is arranged along a first direction. The light guide plate having a light incident surface, a light refraction surface and a light emission surface is disposed on one side of the light source. The light refraction surface has a plurality of grooves parallel to one another in a second direction. The prism sheet is disposed on the light emission surface of the light guide plate, and has a plurality of prism portions parallel to one another in a third direction and on a surface of the prism sheet facing the light emission surface. The second direction is substantially perpendicular to the third direction, and an acute angle formed between the first direction and the third direction is less than or equal to 7 degrees.