Abstract: An implantation device for prompt subcutaneous implantation of a sensor to measure a physiological signal of an analyte in a biofluid of a living body is disclosed. The implantation device includes a housing, an implantation module, a detachable module and a bottom cover. The housing has a bottom opening. The implantation module includes an implanting device and a needle extracting device. The detachable module includes the sensor detachably engaged with the implantation module; and a base configured to mount the sensor thereon. The bottom cover is detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space. The implantation module and the detachable module are accommodated in the accommodating space. The bottom cover has an operating portion configured to bear a force, and a supporting portion is formed on the opposite end of the operating portion.

Abstract: An implantation device for prompt subcutaneous implantation of a sensor to measure a physiological signal of an analyte in a biofluid of a living body is disclosed. The implantation device includes a housing, an implantation module, a detachable module and a bottom cover. The housing has a bottom opening. The implantation module includes an implanting device and a needle extracting device. The detachable module includes the sensor detachably engaged with the implantation module; and a base configured to mount the sensor thereon. The bottom cover is detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space. The implantation module and the detachable module are accommodated in the accommodating space. The bottom cover has an operating portion configured to bear a force, and a supporting portion is formed on the opposite end of the operating portion.

Abstract: The present invention provides a method for reducing measurement interference of a micro biosensor, wherein the micro biosensor is used to measure a target analyte in a biofluid during a period, and the period includes first sub-time zones and second sub-time zones. The method includes performing a interference eliminating action in the T1 zone, in which a second sensing section of the micro biosensor consumes an interferant, performing a measurement action in a first T2 zone, in which a first sensing section of the micro biosensor measures and outputs a physiological signal, performing the interference eliminating action in the next T1 zone to consume an interferant, performing the measurement action in the next T2 zone to measure and output a physiological signal, and so on, to obtain a value data of the physiological parameter in all respective T2 zones during the period, and to reduce a measurement interference.

Abstract: A patch for increasing an adhesive strength of a physiological parameter detection device on a skin surface includes a backing and a peelable sheet. The backing is disposed with an adhesive layer having an adhesive surface. The adhesive surface includes a central adhesive portion and an outer adhesive portion, and, upon the central adhesive portion is exposed, the patch is caused to apply a pressure toward the physiological parameter detection device so as to allow the central adhesive portion to be adhered to a top surface of the physiological parameter detection device. The peelable sheet, which is detachably adhered to the adhesive surface for preserving the adhesive surface, includes an inner peelable portion and an outer peelable portion. After the central adhesive portion is exposed, the outer peelable sheet continuously provides a supporting force for the backing so as to allow the backing to be easily and evenly adhered.

Abstract: A physiological signal monitoring device includes a base and a transmitter. The base is provided with a biosensor. The transmitter is removably coupled to the base, and includes a casing and an electrostatic-discharge protective unit. The casing has a socket for the biosensor to be removably inserted thereinto. The electrostatic-discharge protective unit is disposed to at least surround the periphery of the socket to dispel static electricity when electrostatic discharge occurs.

Abstract: A method for activating a physiological signal sensing device through a handheld device to measure a physiological signal of an analyte in biological fluids is provided. The physiological signal sensing device includes a transmitter including a power unit, a switch unit, a magnetic field sensing unit and a processing unit. The method includes: establishing an inductive magnetic field between the handheld device and the transmitter, causing the magnetic field sensing unit to generate an inductive signal; in a first operating cycle, activating the switch unit by the inductive signal, causing the power unit to connect to the processing unit to activate the processing unit; providing an activation signal by the processing unit to turn on the switch unit; causing the switch unit to enter a self-maintaining state; and in a second operating cycle, connecting the power unit to the processing unit through the switch unit in the self-maintaining state.

Abstract: An implantable micro-biosensor includes a substrate, a first working electrode, at least one second working electrode, and at least one counter electrode. The first working electrode includes a first sensing section driven by a first potential difference to measure a physiological signal. The second working electrode includes a second sensing section driven by a second potential difference to consume an interfering substance. The counter electrode cooperates with the first working electrode to measure the physiological signal, cooperates with the second working electrode to consume the interfering substance, and selectively cooperates with the first or second working electrode to regenerate silver halide.

Abstract: A physiological signal monitoring device includes a base, a biosensor mounted to the base, a transmitter, and a sealing unit. The base is adapted to be mounted to a skin surface of a host. The biosensor includes a mounting seat and a sensing member that is mounted to the mounting seat. The sensing member is adapted to be partially inserted underneath the skin surface of the host for measuring an analyte of the host and to send a corresponding physiological signal. The transmitter is for receiving and transmitting the physiological signal, and has a bottom portion. The transmitter covers the base while the bottom portion faces the base. The sensing member is coupled to the transmitter. The sealing unit is used to seal paths through which a liquid possibly penetrates into an interior of the physiological signal monitoring device so as to avoid damage of the device.

Abstract: A physiological signal monitoring device includes a base and a transmitter. The base is provided with a biosensor. The transmitter is removably coupled to the base, and includes a casing and an electrostatic-discharge protective unit. The casing has a socket for the biosensor to be removably inserted thereinto. The electrostatic-discharge protective unit is disposed to at least surround the periphery of the socket to dispel static electricity when electrostatic discharge occurs.

Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of steel balls. The sensing member is removably inserted into the socket. The steel balls are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the steel balls is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.

Abstract: A physiological signal monitoring device includes a base, a biosensor mounted to the base, a transmitter, and a sealing unit. The base is adapted to be mounted to a skin surface of a host. The biosensor includes a mounting seat and a sensing member that is mounted to the mounting seat. The sensing member is adapted to be partially inserted underneath the skin surface of the host for measuring an analyte of the host and to send a corresponding physiological signal. The transmitter is for receiving and transmitting the physiological signal, and has a bottom portion. The transmitter covers the base while the bottom portion faces the base. The sensing member is coupled to the transmitter. The sealing unit is used to seal paths through which a liquid possibly penetrates into an interior of the physiological signal monitoring device so as to avoid damage of the device.

Abstract: An insertion device includes a cover body and an insertion module. The insertion module is disposed in the cover body, and includes a main body, an insertion seat, a pre-compressed first elastic member, a retraction seat and a pre-compressed second elastic member. The restoring force of the pre-compressed first elastic member is configured not to act on the cover body during depression of the cover body.

Abstract: An insertion device includes a cover body, an insertion module. The insertion module is disposed in the cover body, and includes a main body, an insertion seat, a first elastic member, a retraction seat and a second elastic member. When the cover body is depressed, the insertion seat is driven by the first elastic member to perform an automatic-insertion operation and to collapse a limiting structure between the insertion seat and the cover body. A limiting structure between the insertion seat and the retraction seat collapses upon the collapse of the limiting structure between the insertion seat and the cover body, so that the retraction seat is driven by the second elastic member to perform an automatic-retraction operation.

Abstract: A method for manufacturing an implantable micro-biosensor includes the steps of: a) providing a substrate, b) forming on a first surface of the substrate a first working electrode which at least includes a first sensing section including a first conductive material, c) forming on the first surface of the substrate at least one second working electrode which at least includes a second sensing section disposed proximate to at least one side of the first sensing section, and d) forming a chemical reagent layer which at least covers the first conductive material of the first sensing section and which reacts with the analyte to produce a product.

Abstract: An insertion device includes an upper casing, a lower casing and an insertion module. When the lower casing is coupled to the upper casing, an abutment portion of the lower casing limits movement of a casing engaging structure of the upper casing, such that the upper casing cannot move downwardly so as to prevent unintentional insertion operation of the insertion device.

Abstract: A health management supply organizer is disclosed. The health management supply organizer includes a closeable body adapted to receive a plurality of health monitoring supplies. The plurality of health monitor supplies include at least a transmitter container for receiving a transmitter, a charger for the transmitter and a splitter for splitting a used sensor module and the transmitter. The closeable body includes a first leaf, a second leaf and an end portion connecting the first leaf and the second leaf, wherein the first leaf and the second leaf are foldable about the end portion. The first leaf has a plurality of compartments adapted to receive the plurality of health monitoring supplies respectively.

Abstract: A physiological signal monitoring device includes a base including a base body that has a bottom plate and an opening, a biosensor mounted to the base, and a transmitter removably mounted to the base body. The base further includes a first coupling structure disposed on a top surface of the bottom plate, and the transmitter includes a second coupling structure coupled to the first coupling structure when the transmitter is mounted to the base body. When the first and second coupling structures are coupled to each other, they are disposed to be distal from a periphery cooperatively defined by the base and the transmitter. They are uncoupled from each other when an external force is applied through the opening of the base body to separate the transmitter from the base.

Abstract: An insertion needle structure includes a needle sharp and a needle body. The needle body is integrally connected to the needle sharp and has a receiving space for receiving the biosensor. The needle body includes a base wall, two side walls, two slope sections and two curved connecting sections. The side walls are located at two sides of the base wall, respectively, the side walls are at least partially nonparallel, and each of the side walls is at least partially flat. Each of the slope sections is connected between each of the side walls and the needle sharp, and each of the slope sections is curved. Each of the curved connecting sections is connected between each of the side walls and the base wall and between each of the slope sections and the base wall. The needle sharp extends from the base wall and the curved connecting sections.

Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a biosensor to measure a physiological signal representative of a physiological parameter associated with an analyte in a biofluid. The biosensor includes two working electrodes at least partially covered by a chemical reagent and two counter electrodes having silver and a silver halide, and each silver halide has an initial amount.