Patents by Inventor Chih-Wei Ho

Chih-Wei Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060029974
    Abstract: An on-spot selectively activated hydrophobic slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing a functional group protected by a protecting group, wherein the functional group is imide or cyclic amide, and the protecting group is a photo acid group such as a tosyloxy group. The hydrophobic copolymer coated on a substrate is then subjected to selective photolithographical activation so that the slide will have functional active copolymer spots separated by inactive copolymers. The resulting slide is suitable for the preparation of high-density and high-efficiency bio-chip/microarray.
    Type: Application
    Filed: October 5, 2005
    Publication date: February 9, 2006
    Inventors: Bor-Iuan Jan, Jia-Huey Tsao, Chih-Wei Ho, Chao-Chi Pan
  • Publication number: 20060029973
    Abstract: An on-spot selectively activated hydrophobic slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing a functional group protected by a protecting group, wherein the functional group is imide or cyclic amide, and the protecting group is a photo acid group such as a tosyloxy group. The hydrophobic copolymer coated on a substrate is then subjected to selective photolithographical activation so that the slide will have functional active copolymer spots separated by inactive copolymers. The resulting slide is suitable for the preparation of high-density and high-efficiency bio-chip/microarray.
    Type: Application
    Filed: October 5, 2005
    Publication date: February 9, 2006
    Inventors: Bor-Iuan Jan, Jia-Huey Tsao, Chih-Wei Ho, Chao-Chi Pan
  • Patent number: 6974529
    Abstract: A hand-held electrophoresis detection device and support thereof. The hand-held electrophoresis detection device includes a support and a cartridge. The cartridge attaches a sample, and is disposed in the support in a detachable manner.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: December 13, 2005
    Assignee: Industrial Technology Research Institute
    Inventors: Chung-Fan Chiou, Chih-Wei Ho, Bor-Iuan Jan, Jian Je Jian, Chien-Tsung Wu, Hsi-Hsin Shih
  • Patent number: 6960468
    Abstract: The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: November 1, 2005
    Assignee: Industrial Technology Research Institute
    Inventors: Bor-Iuan Jan, Jia-Huey Tsao, Chih-Wei Ho, Yu-Ching Liu, Chao-Chi Pan, Zu-Sho Chow, Yao-Sung Chang, Cheng-Tao Wu, Wen-Hsun Kuo
  • Publication number: 20050189498
    Abstract: An irradiation apparatus for a photodynamic treatment. The irradiation apparatus includes a main body, a high power light emitting element, an optical lens assembly and an optical fiber. The high power light emitting element is disposed on the main body to output light. The optical lens assembly is adjacent to the high power light emitting element and disposed on the main body to receive the light from the high power light emitting element. The optical fiber has an input end and an output end. The input end is coupled to the optical lens assembly to receive and transmit the light from the optical lens assembly.
    Type: Application
    Filed: August 12, 2003
    Publication date: September 1, 2005
    Inventors: Adrian Wing Fai Lo, Hong-Shi Cao, Jung-Tsung Hsu, Ming-I Lee, Chin-Tin Chen, Chih-Wei Ho
  • Publication number: 20050170361
    Abstract: A method of preparing reaction regions for biochips. First, a first member and a second member are provided as two carriers of biochips. At least one spacer is disposed between the first member and the second member to form a reaction region between the first member and the second member. Then, a sample solution is filled in the reaction regions.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 4, 2005
    Inventors: Chih-Wei Ho, Wen-Yeh Liao, Chien-Tsung Wu, Chao-Chi Pan
  • Publication number: 20050170383
    Abstract: A microarray hybridization assembly for conducting hybridization assay analysis is disclosed. The microarray assembly comprises a slide, a slide cover, and a spacer disposed between the slide and slide cover. The slide cover is placed over the slide and the spacer maintains a gap between the parallel surfaces of the slide and slide cover to create a reaction region for hybridization reactions between attached probe molecules and target molecules of a hybridization solution. The slide assembly is placed into a heat shrinkage bag. The bag and slide assembly are then heated in a heat cycle sufficient to seal the bag around at least three sides of the slide assembly. An optional heat shrinkage cap can be fitted over the fourth side of the slide assembly and heated in a second heat cycle to seal the fourth side of the slide assembly after a hybridization solution is introduced into the reaction region of the slide assembly.
    Type: Application
    Filed: November 23, 2004
    Publication date: August 4, 2005
    Inventors: Chien-Tsung Wu, Chao-Chi Pan, Wen-Yeh Liao, Chih-Wei Ho, Yi Chen, Shih-Chiao Tseng, Chia Wang, Shyh-Haur Su
  • Publication number: 20040125617
    Abstract: A programmable photo-coupler-isolated wide band modulator for high voltage power supply is disclosed, which utilizes a high voltage module to step up the input voltage and utilizes a wide band modulator connected with the high voltage module to modulate the high voltage output from the high voltage module for outputting a wide band high voltage, wherein the wide band modulator receives a modulator signal generated by a computer for modulating.
    Type: Application
    Filed: September 22, 2003
    Publication date: July 1, 2004
    Applicant: Industrial Technology Research Institute
    Inventors: Jang-Tzeng Lin, Ching-Fu Hsieh, Chih-Wei Ho, Yuh-Ren Hsieh
  • Publication number: 20040105788
    Abstract: A reactor for a microarray. A first member includes a first fillister for a sample solution or a microarray, a second member is removably disposed on the first member with a second fillister corresponding to the first fillister, and electrodes are disposed on the second member for contacting the sample solution.
    Type: Application
    Filed: July 17, 2003
    Publication date: June 3, 2004
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chung-Fan Chiou, Bor-Iuan Jan, Chih-Wei Ho, Shu-Ju Yang
  • Patent number: 6733894
    Abstract: The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: May 11, 2004
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Wei Ho, Zu-Sho Chow, Bor-Iuan Jan, Jia-Huey Tsao, Chao-Chi Pan, Wen-Hsun Kuo, Yao-Sung Chang, Cheng-Tao Wu, Yu-Ching Liu
  • Publication number: 20040062854
    Abstract: The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 1, 2004
    Inventors: Bor-Iuan Jan, Jia-Huey Tsao, Chih-Wei Ho, Yu-Ching Liu, Chao-Chi Pan, Zu-Sho Chow, Yao-Sung Chang, Cheng-Tao Wu, Wen-Hsun Kuo
  • Publication number: 20040045825
    Abstract: A cartridge for an electrophoresis detection device and a manufacturing method thereof. The cartridge includes a first member, a second member, and a capillary. The first member includes a first concave portion. The second member includes a second concave portion corresponding to the first concave portion. The second member is combined with the first member in a manner such that the second concave portion faces the first concave portion. The capillary is disposed in the first concave portion and the second concave portion in a manner such that it protrudes from the first and second members.
    Type: Application
    Filed: May 12, 2003
    Publication date: March 11, 2004
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chung-Fan Chiou, Chih-Wei Ho, Bor-Iuan Jan, Jian-Je Jian, Chien-Tsung Wu, Hsi-Hsin Shih
  • Publication number: 20040031687
    Abstract: A hand-held electrophoresis detection device and support thereof. The hand-held electrophoresis detection device includes a support and a cartridge. The cartridge attaches a sample, and is disposed in the support in a detachable manner.
    Type: Application
    Filed: December 11, 2002
    Publication date: February 19, 2004
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chung-Fan Chiou, Chih-Wei Ho, Bor-Iuan Jan, Jian Je Jian, Chien-Tsung Wu, Hsi-Hsin Shih
  • Publication number: 20040003998
    Abstract: An electrophoresis separation apparatus. The electrophoresis separation apparatus detects samples, and comprises a main portion, a cartridge, and a sensor. The main portion includes a receiving portion, and controls the detection of the samples. The cartridge is disposed in the receiving portion of the main portion in a detachable manner, and includes a detection column.
    Type: Application
    Filed: December 13, 2002
    Publication date: January 8, 2004
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chih-Wei Ho, Chung-Fan Chiou, Bor-Iuan Jan, Chien-Tsung Wu, Jian-Je Jian
  • Publication number: 20030188970
    Abstract: An electrophoresis separation apparatus using a hand-held electrophoresis detection device. The hand-held electrophoresis detection device includes a body and a cartridge disposed on the body in a detachable manner, and provided with at least one detecting column. The electrophoresis separation apparatus detect samples, and comprises a main portion and the hand-held electrophoresis detection device. The main portion controls the process of sample-detecting. The hand-held electrophoresis detection device is electrically coupled to the main portion in a separable manner. The detecting column is provided with a first end and a second end. The first end is provided with a first voltage, and the second end is provided with a second voltage. The sample is attached to the second end of the detecting column. The sample moves from the second end to the first end through the detecting column by a voltage differential between the first voltage and the second voltage.
    Type: Application
    Filed: October 18, 2002
    Publication date: October 9, 2003
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chung-Fan Chiou, Chih-Wei Ho, Bor-Iuan Jan, Chun-Ju Chang, Jia-Huey Tsao, Chao-Chih Pan
  • Patent number: 6605363
    Abstract: The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: August 12, 2003
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Wei Ho, Zu-Sho Chow, Bor-Iuan Jan, Jia-Huey Tsao, Chao-Chi Pan, Wen-Hsun Kuo, Yao-Sung Chang, Cheng-Tao Wu, Yu-Ching Liu
  • Publication number: 20030054434
    Abstract: The invention discloses a method for preparing an active slide, including introducing a monomer containing an aldehyde group, or a mixture of a monomer containing an aldehyde group and an acidic functional group provider into a plasma chamber; and depositing the aldehyde group and acidic functional group onto the surface of an organic or inorganic matrix using plasma deposition to form a slide comprising a layer of polymerized actively functional groups thereon. The aldehyde groups and negatively charged groups are deposited on the surface of the active slide, such that the bio-molecules bound thereto possess the properties of an inducible orientation and thus form a mono-layer.
    Type: Application
    Filed: November 6, 2002
    Publication date: March 20, 2003
    Inventors: Zu-Sho Chow, Jia-Huey Tsao, Wen-Hsun Kuo, Chih-Wei Ho, Bor-Iuan Jan, Chao-Chi Pan, Yao-Sung Chang, Cheng-Tao Wu, Yu-Ching Liu
  • Patent number: 6528291
    Abstract: A method is provided for preparing an active slide, including introducing a monomer containing an aldehyde group, or a mixture of a monomer containing an aldehyde group and an acidic functional group provider into a plasma chamber; and depositing the aldehyde group and acidic functional group onto the surface of an organic or inorganic matrix using plasma deposition to form a slide comprising a layer of polymerized actively functional groups thereon. The aldehyde groups and negatively charged groups are deposited on the surface of the active slide, such that the bio-molecules bound thereto possess the properties of an inducible orientation and thus form a mono-layer.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: March 4, 2003
    Assignee: Industrial Technology Research Institute
    Inventors: Zu-Sho Chow, Jia-Huey Tsao, Wen-Hsun Kuo, Chih-Wei Ho, Bor-Iuan Jan, Chao-Chi Pan, Yao-Sung Chang, Cheng-Tao Wu, Yu-Ching Liu
  • Publication number: 20030017560
    Abstract: The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.
    Type: Application
    Filed: September 19, 2002
    Publication date: January 23, 2003
    Inventors: Chih-Wei Ho, Zu-Sho Chow, Bor-Iuan Jan, Jia-Huey Tsao, Chao-Chi Pan, Wen-Hsun Kuo, Yao-Sung Chang, Cheng-Tao Wu, Yu-Ching Liu
  • Publication number: 20020182719
    Abstract: An on-spot selectively activated hydrophobic slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing a functional group protected by a protecting group, wherein the functional group is imide or cyclic amide, and the protecting group is a photo acid group such as a tosyloxy group. The hydrophobic copolymer coated on a substrate is then subjected to selective photolithographical activation so that the slide will have functional active copolymer spots separated by inactive copolymers. The resulting slide is suitable for the preparation of high-density and high-efficiency bio-chip/microarray.
    Type: Application
    Filed: July 8, 2002
    Publication date: December 5, 2002
    Inventors: Bor-Iuan Jan, Jia-Huey Tsao, Chih-Wei Ho, Chao-Chi Pan