Patents by Inventor Ching-Whan Ko
Ching-Whan Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140045257Abstract: The present invention is directed to improvements in gasification for use with synthesis gas fermentation. Further, the present invention is directed to improvements in gasification for the production of alcohols from a gaseous substrate containing at least one reducing gas containing at least one microorganism.Type: ApplicationFiled: October 18, 2013Publication date: February 13, 2014Applicant: Ineos Bio LimitedInventors: James L. Gaddy, Ching-Whan Ko, J. Randy Phillips, M. Sean Slape
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Publication number: 20140045246Abstract: A process for fermenting syngas is provided which is effective for decreasing an amount of time needed to inoculate a main reactor. The process includes propagating a culture of acetogenic bacteria to provide an incoulum for a main reactor and fermenting syngas in the main reactor.Type: ApplicationFiled: October 22, 2013Publication date: February 13, 2014Applicant: INEOS BIO SAInventors: Peter Simpson Bell, Ching-Whan Ko
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Patent number: 8647851Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: GrantFiled: December 8, 2011Date of Patent: February 11, 2014Assignee: Ineos Bio LimitedInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20140038278Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising adding a molecular oxygen-containing gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: ApplicationFiled: October 8, 2013Publication date: February 6, 2014Applicant: INEOS USA LLCInventors: Bhagya Chandra Sutradhar, Ching-Whan KO
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Patent number: 8642302Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: GrantFiled: December 12, 2011Date of Patent: February 4, 2014Assignee: Ineos Bio LimitedInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Patent number: 8642301Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: GrantFiled: December 7, 2011Date of Patent: February 4, 2014Assignee: Ineos Bio LimitedInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Publication number: 20130316421Abstract: A process for fermenting syngas and a fermentation medium provides high ethanol productivity while removing medium components that were previously thought to be essential. The process is effective for providing a specific STY of at least about 1 g ethanol/(L·day·gram cells). In this aspect, the fermentation medium has a weight ratio of NH4+ to B of about 625:1 or more, or a weight ratio of NH4+ to Mn of about 4050:1 or more, or a weight ratio of NH4+ to Mo of about 2500:1 or more, or a ratio of NH4+ to Cu of about 4050:1 or more; or the fermentation medium has a weight ratio of P to B of about 30:1 or more, or a weight ratio of P to Mn of about 190:1 or more, or a weight ratio of P to Mo of about 120:1 or more, or a weight ratio of Mn to Cu of about 190:1 or more; or the fermentation medium has a weight ratio of K to B of about 35:1 or more, or a weight ratio of K to Mn of about 245:1 or more, or a weight ratio of K to Mo of about 150:1 or more, or a weight ratio of K to Cu of about 245:1 or more.Type: ApplicationFiled: May 9, 2013Publication date: November 28, 2013Applicant: INEOS BIO S.A.Inventors: Syrona Scott, Ryan Senaratne, Ching-Whan Ko
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Publication number: 20130316422Abstract: A process is provided for fermentation of syngas that is effective for reducing conductivity and providing an alcohol STY of about 10 g ethanol/(L·day). The process includes introducing the syngas into a reactor vessel and providing a nitrogen feed rate to the reactor vessel of about 100 mg or more nitrogen/gram of cells produced. Fermentation of the syngas is effective for providing a fermentation medium having an average conductivity of about 16 mS/cm or less and an STY of 10 g ethanol/(L·day) or more.Type: ApplicationFiled: May 9, 2013Publication date: November 28, 2013Applicant: INEOS BIO S.A.Inventors: Syrona Scott, Song Liu, Ching-Whan Ko
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Publication number: 20130316420Abstract: A process for fermenting syngas and a fermentation medium provides high ethanol productivity while removing medium components that were previously thought to be essential. The process is effective for providing a specific STY of at least about 1 g ethanol/(L·day·gram cells). In this aspect, the fermentation medium has less than about 1.04 ppm boron, less than about 0.16 ppm manganese, less than about 0.26 ppm molybdenum, or less than about 0.16 ppm copper.Type: ApplicationFiled: May 8, 2013Publication date: November 28, 2013Inventors: Syrona Scott, Ryan Senaratne, Ching-Whan Ko
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Patent number: 8592190Abstract: The present invention is directed to improvements in gasification for use with synthesis gas fermentation. Further, the present invention is directed to improvements in gasification for the production of alcohols from a gaseous substrate containing at least one reducing gas containing at least one microorganism.Type: GrantFiled: June 11, 2009Date of Patent: November 26, 2013Assignee: Ineos Bio LimitedInventors: James L. Gaddy, Ching-Whan Ko, J. Randy Phillips, M. Sean Slape
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Patent number: 8592191Abstract: A process for fermenting syngas is provided which is effective for decreasing an amount of time needed to inoculate a main reactor. The process includes propagating a culture of acetogenic bacteria to provide an inoculum for a main reactor and fermenting syngas in the main reactor.Type: GrantFiled: May 16, 2012Date of Patent: November 26, 2013Assignee: INEOS Bio SAInventors: Peter Simpson Bell, Ching-Whan Ko
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Patent number: 8585789Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding carbon dioxide gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: GrantFiled: April 13, 2010Date of Patent: November 19, 2013Assignee: INEOS USA LLCInventors: Bhagya Chandra Sutradhar, Ching-Whan Ko
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Patent number: 8580152Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising adding a molecular oxygen-containing gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: GrantFiled: April 13, 2010Date of Patent: November 12, 2013Assignee: INEOS USA LLCInventors: Bhagya Chandra Sutradhar, Ching-Whan Ko
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Patent number: 8574879Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: GrantFiled: December 14, 2011Date of Patent: November 5, 2013Assignee: Ineos Bio LimitedInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Publication number: 20130005011Abstract: A bioreactor is provided that includes a main reactor having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. The bioreactor also includes a growth reactor continuous with the main reactor and having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. A method is also provided where acetogenic bacteria are contacted with syngas in a growth fermentor section of a reactor vessel that is continuous with a main fermentor section of a reactor vessel.Type: ApplicationFiled: May 15, 2012Publication date: January 3, 2013Inventors: Peter Simpson Bell, Ching-Whan Ko
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Publication number: 20130005014Abstract: A process and apparatus is provided which are effective for improving CO mass transfer. The process includes introducing syngas into a reactor vessel through a gas sparger located below a liquid level in the reactor vessel. The syngas being introduced at a flow rate effective for maintaining a pressure inside of the reactor vessel of at least about 1 psig. An agitation energy of about 0.01 to about 12 kWatts/m3 medium is provided. The process is effective for providing a volumetric CO mass transfer coefficient of about 100 to about 1500 per hour.Type: ApplicationFiled: May 15, 2012Publication date: January 3, 2013Inventors: Peter Simpson Bell, Ching-Whan Ko
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Publication number: 20130005021Abstract: A process for fermenting syngas is provided which is effective for decreasing an amount of time needed to inoculate a main reactor. The process includes propagating a culture of acetogenic bacteria to provide an inoculum for a main reactor and fermenting syngas in the main reactor.Type: ApplicationFiled: May 16, 2012Publication date: January 3, 2013Inventors: Peter Simpson Bell, Ching-Whan Ko
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Publication number: 20130005010Abstract: A bioreactor is provided that includes a main reactor having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. The bioreactor also includes a growth reactor continuous with the main reactor and having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. A method is also provided where acetogenic bacteria are contacted with syngas in a growth fermentor section of a reactor vessel that is continuous with a main fermentor section of a reactor vessel.Type: ApplicationFiled: May 15, 2012Publication date: January 3, 2013Inventors: Peter Simpson Bell, Ching-Whan Ko
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Publication number: 20120122173Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 13, 2011Publication date: May 17, 2012Applicant: INEOS BIO LIMITEDInventors: James L. GADDY, Dinesh K. ARORA, Ching-Whan KO, John Randall PHILLIPS, Rahul BASU, Carl V. WIKSTROM, Edgar C. CLAUSEN
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Publication number: 20120115198Abstract: A stable continuous method for producing ethanol from anaerobic fermentation of a gaseous substrate containing at least one reducing gas in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 20, 2011Publication date: May 10, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen