Patents by Inventor Ching-Whan Ko
Ching-Whan Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120094349Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 12, 2011Publication date: April 19, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20120094346Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 14, 2011Publication date: April 19, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20120088283Abstract: A stable continuous method for producing ethanol from anaerobic fermentation of a gaseous substrate containing at least one reducing gas in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 20, 2011Publication date: April 12, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Publication number: 20120088282Abstract: A stable continuous method for producing ethanol from anaerobic fermentation of a gaseous substrate containing at least one reducing gas in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 19, 2011Publication date: April 12, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20120088284Abstract: A stable continuous method for producing ethanol from anaerobic fermentation of a gaseous substrate containing at least one reducing gas in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 20, 2011Publication date: April 12, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Publication number: 20120083022Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 8, 2011Publication date: April 5, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20120077240Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: December 7, 2011Publication date: March 29, 2012Applicant: INEOS BIO LIMITEDInventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wilkstrom, Edgar C. Clausen
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Publication number: 20110248218Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising adding a molecular oxygen-containing gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: ApplicationFiled: April 13, 2010Publication date: October 13, 2011Inventors: Bhagya Chandra Sutradhar, Ching-Whan Ko
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Publication number: 20110250662Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding carbon dioxide gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: ApplicationFiled: April 13, 2010Publication date: October 13, 2011Inventors: Bhagya Chandra Sutradhar, Ching-Whan Ko
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Publication number: 20110250661Abstract: The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding a methane-containing gas and optionally adding water or steam into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.Type: ApplicationFiled: April 13, 2010Publication date: October 13, 2011Inventors: Bhagya Chandra Sutradhar, Ching-Whan Ko
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Publication number: 20100317077Abstract: The present invention is directed to improvements in gasification for use with synthesis gas fermentation. Further, the present invention is directed to improvements in gasification for the production of alcohols from a gaseous substrate containing at least one reducing gas containing at least one microorganism.Type: ApplicationFiled: June 11, 2009Publication date: December 16, 2010Inventors: James L. Gaddy, Ching-Whan Ko, J. Randy Phillips, M. Sean Slape
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Publication number: 20100227377Abstract: The present invention relates to methods for sustaining microorganism culture in a syngas fermentation reactor in decreased concentration or absence of various substrates comprising: adding carbon dioxide and optionally alcohol; maintaining free acetic acid concentrations; and performing the above mentioned steps within specified time.Type: ApplicationFiled: March 9, 2009Publication date: September 9, 2010Inventors: Stephen S. Adams, Syrona Scott, Ching-Whan Ko
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Publication number: 20080213848Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: October 22, 2007Publication date: September 4, 2008Applicant: Emmaus Foundation, Inc.Inventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Patent number: 7285402Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: GrantFiled: July 23, 2001Date of Patent: October 23, 2007Assignee: Emmaus Foundation, Inc.Inventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Patent number: 7196218Abstract: A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. Solvent mixtures formed of such a modified solvent with a desired co-solvent, preferably a low boiling hydrocarbon, are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.Type: GrantFiled: May 5, 2004Date of Patent: March 27, 2007Assignees: Celanese International Corporation, Bioengineering Resources, Inc.Inventors: James L. Gaddy, Edgar C. Clausen, Ching-Whan Ko, Leslie E. Wade, Carl V. Wikstrom
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Publication number: 20040236149Abstract: A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. Solvent mixtures formed of such a modified solvent with a desired co-solvent, preferably a low boiling hydrocarbon, are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.Type: ApplicationFiled: May 5, 2004Publication date: November 25, 2004Applicants: Bioengineering Resources, Inc., Celanese International CorporationInventors: James L. Gaddy, Edgar C. Clausen, Ching-Whan Ko, Leslie E. Wade, Carl V. Wikstrom
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Patent number: 6753170Abstract: A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. Solvent mixtures formed of such a modified solvent with a desired co-solvent, preferably a low boiling hydrocarbon, are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.Type: GrantFiled: January 16, 2002Date of Patent: June 22, 2004Assignees: Bioengineering Resources, Inc., Celanese International CorporationInventors: James L. Gaddy, Edgar C. Clausen, Ching-Whan Ko, Leslie E. Wade, Carl V. Wikstrom
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Publication number: 20030211585Abstract: A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.Type: ApplicationFiled: March 11, 2003Publication date: November 13, 2003Inventors: James L. Gaddy, Dinesh K. Arora, Ching-Whan Ko, John Randall Phillips, Rahul Basu, Carl V. Wikstrom, Edgar C. Clausen
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Publication number: 20020086378Abstract: A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. Solvent mixtures formed of such a modified solvent with a desired co-solvent, preferably a low boiling hydrocarbon, are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.Type: ApplicationFiled: January 16, 2002Publication date: July 4, 2002Inventors: James L. Gaddy, Edgar C. Clausen, Ching-Whan Ko, Leslie E. Wade, Carl V, Wikstrom
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Patent number: RE39175Abstract: A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. This solvent is substantially devoid of mono-alkyl amines and alcohols. Solvent mixtures formed of such a modified solvent with a desired cosolvent, preferably a low boiling hydrocarbon which forms an azeotrope with water are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production.Type: GrantFiled: September 7, 1999Date of Patent: July 11, 2006Assignees: Bioengineering Resources, Inc., Celanese International CorporationInventors: James L. Gaddy, Edgar C. Clausen, Ching-Whan Ko, Leslie E. Wade, Carl V. Wikstrom