Abstract: Systems and methods for creating a customizable dummy finite element model for a dummy hardware model. First finite element factor profiles for the dummy hardware model that match certification corridors for the dummy hardware model are identified, a mapping function based on the first finite element factor profiles that allows second finite element model profiles for the dummy hardware model to be interpolated from the first finite element factor profiles is defined, and a customizable dummy finite element model for the dummy hardware model that incorporates the mapping function is generated.

Abstract: The described technology provides a method for dynamically adjusting operating voltage of a device, including receiving device characteristics data related to a device, performing a margining test for the device to generate a performance curve characterizing variation of the device's current performance speeds at various operating voltages from expected performance speeds at the various operating voltages, determining an operating voltage for the device based on the device characteristics data and the performance curve, and adjusting the operating of the device based on the determined operating voltage.

Abstract: Methods and systems for generating an MRI-compatible stimulation program based at least in part on a first set of stimulation parameters of a first stimulation program are presented. For example, a method or system (via a processor) can include receiving the first set of stimulation parameters, wherein the first set of stimulation parameters indicates a first set of stimulation electrodes; modifying the first set of stimulation parameters to generate a second set of stimulation parameters of the MRI-compatible stimulation program by at least one of 1) reducing a value of at least one stimulation parameter of the first set of stimulation parameters or 2) replacing, in the first set of electrodes, a case electrode with at least one electrode of the lead; and initiating a signal that provides the IPG with the MRI-compatible stimulation program.

Abstract: Embodiments described herein comprise a current transformer having a primary winding with multiple primary parallel branches that divide the primary current, and a secondary winding which is placed in any one, or more, branches. The current thus divided in the primary branches produces an alternating magnetic flux which induces alternating current in the secondary winding for an end user application. The invention disclosed herein reduces the weight and size of the current transformer drastically compared to the existing conventional current transformers.

Abstract: There is provided a computer system for conducting auctions over a computer network, comprising: a posting system operable to post on the computer network information describing each lot of a plurality of lots that are available for bidding by a plurality of bidders, each lot including at least one item; a bid receiving system for receiving a bid relating to at least a portion of a lot of the plurality of lots, characterized in that the posting system is operable to define an n-dimensional matrix, where n is at least 2, wherein the matrix comprises the plurality of lots, and wherein the posting system is operable to post the matrix on the computer network. A computer-implemented method relating to the computer system, and a computer-readable medium containing instructions for implementing the computer-implemented method, are also provided.

Abstract: Interfaces are disclosed for configuring the parameters of anodic and cathodic stimulation that is provided by an implantable medical device. The interfaces enable the specification of transitions between anodic and cathodic modes of stimulation and continuous interleaving of anodic and cathodic modes of stimulation. Transitions between anodic and cathodic modes of stimulation can include linear or user-customized adjustments of stimulation parameters of the anodic and cathodic modes during a transition period. Continuous interleaving of anodic and cathodic modes of stimulation can include repeating, continuous adjustments of stimulation parameters of the anodic and cathodic modes according to user-customized parameters and user-defined time apportionments. Interfaces additionally provide information regarding the relative energy usages of the different stimulation modes and visualizations of the effects of adjustments of the stimulation modes on energy usage.

Abstract: A system may comprise a controller configured to implement an algorithm on a received input to produce an output, and a system input operably connected to the controller and configured for use to enter at least one input into the algorithm. The at least one input may include: one or more sensor inputs or one or more inputs from smart appliances or one or more user inputs regarding at least one of time of day or mental or physical state; or at least one of a user-inputted disease, a user-inputted disease state, or a user-inputted symptom-related information into the algorithm. The controller may be configured to provide instructions through the system output to implement a system action. The algorithm implemented by the controller may be configured to identify one, or a combination of more than one, of the neuromodulation modes as a candidate neuromodulation mode based on the input(s).

Abstract: Methods and systems can facilitate visualizing cathodic and anodic stimulation separately. Alternately, the methods and systems may separately visualize stimulation of different neural elements, such as nerve fibers and neural cells. These methods and systems can further facilitate programming an electrical stimulation system for stimulating patient tissue.

Abstract: A system for adjusting neuromodulation parameters used by a neuromodulator operably connected to a plurality of electrodes to modulate a neural target, may comprise a translation trigger detector configured to determine that a translation trigger has occurred, a first parameter setting storage configured to store first parameter settings for use by the neuromodulator to modulate the neural target, and a neuromodulation parameter translator. The neuromodulation parameter translator may be operably connected to the translation trigger detector to automatically translate the first parameter settings into a second parameter settings in response to determining the translation trigger has occurred, and replace the first parameter settings with the second parameter settings, or store the second parameter settings in a second parameter setting storage.

Abstract: Implantable medical devices (IMD) such as those used in Deep Brain Stimulation application are commonly replaced when the device's useful life expires. At the time of replacement, the electrodes that were connected to the initial IMD are typically reused with the replacement IMD. It is desirable for the replacement IMD to utilize the stimulation parameters that were being utilized to provide stimulation in the initial IMD, but it is important that the electrodes be connected to the replacement IMD in a similar manner as they were connected to the initial IMD if stimulation parameters are reused. A connected electrode profile that includes measurements of electrical parameters associated with the electrodes can be generated in the initial IMD and the replacement IMD, and the profiles can be compared to determine whether the electrodes are connected in a similar manner in the replacement IMD as they were in the initial IMD.

Abstract: Methods, systems, and apparatus for determining that a native application limits access to the native application using account credential requirements, the native application generating an application environment for display on a user device within the native application and operating independent of a browser application that can operate on the user device; obtaining a set of account credentials for indexing environment instances of the native application; instantiating the native application with the set of account credentials; and accessing environment instances of the native application, and for each of the environment instances: generating environment instance data describing content of the environment instance, the content described by the environment instance data including text that a user device displays on the environment instance when the user device displays the environment instance; and indexing the environment instance data for the native application in an index that is searchable by a search en

Abstract: The present invention provides an improved process for the preparation of 8-chloro-1-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione (hereafter referred to as the compound (IV)), which is useful as a key intermediate for the synthesis of Clobazam (referred to as the compound (I)) 7-chloro-1-methyl-5-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione. The process of the present invention further involves transformation of the compound (IV) into Clobazam (I), comprising (a) reacting the compound (II) (as described herein) with monoalkyl malonate in the presence of a coupling agent to obtain the compound (III) (as described herein); followed by the cyclization using a base; (b) reacting the compound-IV (as described herein) obtained from step (a) with methylating agent. The process of the present invention involves formation of novel intermediates methyl 3-((4-chloro-2-(phenylamino)phenyl)amino)-3-oxopropanoate (IIIa) and 3-((4-chloro-2-(phenylamino)phenyl)amino)-3-oxopropanoic acid (V).

Abstract: A system for generating a customized response finite element model for a crash test dummy and the system is configured to implement a method of creating the customized response finite element model for the crash test dummy including the steps of selecting a plurality of finite element factors associated with a crash test dummy, selecting a performance parameter associated with the crash test dummy, and identifying a certification test value associated with the selected performance parameter. The method also includes the steps of determining a performance parameter value as a function of the plurality of finite element factors, determining an optimized factor value for each of the finite element factors to minimize a difference between the performance parameter value and the certification test value, and generating a customized response finite element model for the crash test dummy using the determined optimized value of each of the finite element factors.

Abstract: This document discusses, among other things, systems and methods to receive a first target neuromodulation field location, receive a stimulation pattern, determine a sequence of target neuromodulation field locations based on the first target neuromodulation field location and the stimulation pattern, determine a neuromodulation waveform for each electrode in a plurality of stimulation electrodes for each of the determined target neuromodulation field locations, and deliver the determined neuromodulation waveforms to the plurality of stimulation electrodes to provide the stimulation pattern to a patient to provide a therapy.

Abstract: This document discusses, among other things, systems and methods to receive a target neuromodulation field location within a patient for a neuromodulation field, wherein the target neuromodulation field location is not specific to the patient, receive a waveform file, the waveform file including data to define a waveform morphology for a neuromodulation waveform, wherein the waveform morphology is not specific to the patient, using the waveform file and the target neuromodulation field location to determine a patient-specific neuromodulation waveform, and deliver the patient-specific neuromodulation waveform to the at least one electrode to provide a neuromodulation field at the target neurostimulation field location.

Abstract: Methods and systems for generating an MRI-compatible stimulation program based at least in part on a first set of stimulation parameters of a first stimulation program are presented. For example, a method or system (via a processor) can include receiving the first set of stimulation parameters, wherein the first set of stimulation parameters indicates a first set of stimulation electrodes; modifying the first set of stimulation parameters to generate a second set of stimulation parameters of the MRI-compatible stimulation program by at least one of 1) reducing a value of at least one stimulation parameter of the first set of stimulation parameters or 2) replacing, in the first set of electrodes, a case electrode with at least one electrode of the lead; and initiating a signal that provides the IPG with the MRI-compatible stimulation program.

Abstract: The present invention provides an improved process for the preparation of 8-chloro-1-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione (hereafter referred to as the compound (IV)), which is useful as a key intermediate for the synthesis of Clobazam (referred to as the compound (I)) 7-chloro-1-methyl-5-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione. The process of the present invention further involves transformation of the compound (IV) into Clobazam (I), comprising (a) reacting the compound (II) (as described herein) with monoalkyl malonate in the presence of a coupling agent to obtain the compound (III) (as described herein); followed by the cyclization using a base; (b) reacting the compound-IV (as described herein) obtained from step (a) with methylating agent. The process of the present invention involves formation of novel intermediates methyl 3-((4-chloro-2-(phenylamino) phenyl)amino)-3-oxopropanoate (IIIa) and 3-((4-chloro-2-(phenylamino)phenyl)amino)-3-oxopropanoic acid (V).

Abstract: A system or method for programming an electrical stimulation system can utilize any combination of a number of aids to facilitate communication between the patient and the programmer or clinician. For example, a three dimensional model or two dimensional representation of the human body or portion of the human body can be used by the patient to indicate sites of symptoms, stimulation effects or side effects. Non-textual icons or a graphical scale can be used by the patient to respond to queries by the programmer or clinician.

Abstract: A customized lumbar spine response finite element model for a lumbar spine of a crash test dummy is disclosed. A method of creating the customized lumbar spine response finite element model for the lumbar spine of the crash test dummy includes the steps of identifying two borderline sets of test data profiles for the lumbar spine that match with extreme test data profiles of the lumbar spine of the crash test dummy, varying material properties of the lumbar spine for the crash test dummy, defining a mapping function to adjust the material properties and allowing intermediate sets of the test data profiles to be interpolated from the extreme test data profiles, and creating a single lumbar spine response finite element model for the lumbar spine of the crash test dummy with a user-defined input parameter for the lumbar spine response finite element model that defines a customized response.

Abstract: A customized abdomen insert response finite element model for an abdomen insert of a crash test dummy is disclosed. A method of creating the customized abdomen insert response finite element model for the abdomen insert of the crash test dummy includes the steps of identifying two borderline sets of test data profiles for the abdomen insert that match with the test data profiles of the abdomen insert for the crash test dummy, varying material properties of components of the abdomen insert for the crash test dummy, defining a mapping function to adjust the material properties and allowing intermediate sets of the test data profiles to be interpolated from the test data profiles, and creating a single abdomen insert response finite element model for the abdomen insert of the crash test dummy with a user-defined input parameter for the abdomen insert response finite element model that defines a customized response.