Abstract: The present application provides an antibody, such as a monoclonal antibody (mAb), or an antigen binding fragment thereof, that specifically recognizes TIGIT. Also provided are pharmaceutical compositions, or methods of making and using the antibody or antigen-binding fragment thereof.

Abstract: The present invention provides a pharmaceutical composition comprising a binary conjugate, DC009, which is a conjugate of a thrombolytic peptide (Pro-Ala-Lys) and a tetrahydroisoquinoline compound having two C1-4 alkyl groups via a lysine linking arm, and a pharmaceutical acceptable carrier. The composition has a pH less than 6.5, preferably has a pH about pH 2-5.5 The composition may comprise a pharmaceutical acceptable excipient such as mannitol, sorbitol, sucrose, lactose, or trehalose.

Abstract: A wireless programming method for tire pressure detectors includes the following steps. A wireless programmer sends an activating command. The tire pressure detectors send a responding message. The wireless programmer receives the responding messages and records identification codes in the received responding messages. The wireless programmer sends a stop-responding command to make the tire pressure detector with the identification codes, which is recorded in the wireless programmer, enter a stop-responding mode. The wireless programmer sends the activating command again. The tire pressure detectors not in the stop-responding mode send the responding messages. The wireless programmer receives the responding message and records the identification code in the received responding message. The wireless programmer sends a code to the tire pressure detectors corresponding to the recorded identification code to program the code.

Abstract: A system is configured to manage motor engagement in a vehicle by determining to engage a disengaged motor shaft with a drivetrain, and in response, activating a feedback controller based on a speed of the motor shaft and activating a feedforward controller. The system determines at least one metric for modifying an output of the feedforward controller. The at least one metric is based on the speed of the motor shaft and the desired speed, and may be applied as a gain to the output of the feedforward controller. The system generates a command based on the feedback controller, the feedforward controller, and the at least one metric, and causes the motor shaft and the drivetrain to be engaged based on the speed of the motor shaft and the desired speed. The system nulls output of the feedforward controller as the speed of the motor shaft approaches the desired speed.

Abstract: Techniques for identifying and remedying performance issues of Virtualized Network Functions (VNFs) are discussed. An example method includes outputting a request to a network Element Manager (EM) to create a Virtualized Network Function (VNF) Performance Measurement (PM) job to collect VNF PM data from a VNF and receiving a set of VNF PM data associated with the VNF from the EM. The set of VNF PM data is processed associated with the VNF. A request to the EM is output to create a Virtualization Resource (VR) PM job to collect, through a VNF Manager (VNFM) and a virtualized infrastructure manager (VIM), VR PM data from a VR used by the VNF. Then a set of VR PM data is received from the EM and processed.

Abstract: A semiconductor device includes a hysteresis block configured to generate an output voltage at corresponding disabling enabling voltage levels and a core-voltage-gated (CVG) device configured to receive a core voltage, an input terminal of the hysteresis block is coupled to a control node. The CVG device is configured to alter a control voltage at the control node so as to cause the output voltage of the hysteresis block to be generated at the disabling voltage level in response to the core voltage being at or below a first trigger level. Additionally, the CVG device is configured to alter the control voltage at the control node so as to cause the output voltage of the hysteresis block to be generated at the enabling voltage level in response to the core voltage being at or above a second trigger level, the second trigger level being above the first trigger level.

Abstract: Steam cracking of ethane, a non-catalytic thermochemical process, remains the dominant means of ethylene production. The severe reaction conditions and energy expenditure involved in this process incentivize the search for alternative reaction pathways and reactor designs which maximize ethylene yield while minimizing cost and energy input. According to the present invention, ethylene yields as high as 68% were obtained with a quartz open tube reactor without the use of a catalyst or a cofed stream of oxidizing agents. The open tube reactor design promotes simplicity, low cost, and negligible coke formation. Reactor designs can be optimized to improve the conversion of ethane to ethylene via non-oxidative dehydrogenation, an approach which shows promise for decentralized production of ethylene from natural gas deposits.

Abstract: Some of the present implementations provide a method for a user equipment (UE) for performing a random access (RA) procedure. The method receives, at the UE, an RA configuration and a reference signal received power (RSRP) threshold. The method then determines whether a detected RSRP exceeds the RSRP threshold once the RA procedure is initiated. If the detected RSRP exceeds the RSRP threshold, the method performs a two-step RA procedure.

Abstract: A backlight apparatus includes a circuit board, a control board, and a connection cable connecting the above components. A first light source driver and a second light source driver are disposed on the circuit board and are electrically connected to a plurality of first light sources and a plurality of second light sources respectively. A connector is disposed on the circuit board. The first and second light source drivers are individually electrically coupled in series to the connector. The control board outputs electrical power, a first data stream, and a second data stream. The first light source driver controls the first light sources to light individually according to the first data stream. The second light source driver controls the second light sources to light individually according to the second data stream. Thereby, the circuit board can control the operation of the light sources individually.

Abstract: Disclosed are devices and methods for performing biological and chemical assays, such as immunoassays and nucleic acid assays, more particularly a homogeneous assay that does not use a wash step by using the aggregation and de-aggregation processes of microparticles or nanoparticles.

Abstract: A method of manufacturing a semiconductor device includes dividing a number of dies along an x axis in a die matrix in each exposure field in an exposure field matrix delineated on the semiconductor substrate, wherein the x axis is parallel to one edge of a smallest rectangle enclosing the exposure field matrix. A number of dies is divided along a y axis in the die matrix, wherein the y axis is perpendicular to the x axis. Sequences SNx0, SNx1, SNx, SNxr, SNy0, SNy1, SNy, and SNyr are formed. p*(Nbx+1)?2 stepping operations are performed in a third direction and first sequence exposure/stepping/exposure operations and second sequence exposure/stepping/exposure operations are performed alternately between any two adjacent stepping operations as well as before a first stepping operation and after a last stepping operation. A distance of each stepping operation in order follows the sequence SNx.

Abstract: A tool, such as a tape measure, including a spring-based retraction system is shown. The spring-based retraction system is driven by a spiral spring, that has a variable preformed stress profile along the length of the spring.

Abstract: A voltage regulator with dynamic voltage and frequency tracking is shown. The voltage regulator has power switches converting an input voltage into an output voltage, a control loop, a voltage comparator, and a target voltage generator. The control loop is coupled to the power switches to control the power switches to perform voltage regulation. The voltage comparator compares the output voltage to the target voltage to generate a first control signal to control the control loop. The target voltage generator generates the target voltage for the voltage comparator based on the frequency difference between the target frequency and the critical-path-related frequency, wherein the critical-path-related frequency depends on the output voltage. The power efficiency and response time are improved.

Abstract: Methods for reading a memory are provided. In response to a first address signal, a first signal is obtained according to first data of the memory and a second signal is obtained according to second data of the memory by a decoding circuit. Binary representation of the first signal is complementary to that of the second signal. A first sensing signal is provided according to a reference signal and the first signal and a second sensing signal is provided according to the reference signal and the second signal by a sensing circuit. An output corresponding to the first sensing signal or the second sensing signal is output in response to a control signal, by an output buffer.

Abstract: A light sensing module includes a substrate, a light sensing unit, a first light-transmissive component, and a light shielding layer. The light sensing unit is disposed on the substrate to sense an intensity of a working light beam, and has an upper light receiving surface and a lateral surface perpendicular to the upper light receiving surface. The first light-transmissive component covers the light sensing unit, and has a first refractive index between a refractive index of the light sensing unit and a refractive index of air. The light shielding layer surrounds the lateral surface and is covered by the first light-transmissive component.

Abstract: The inbred rice line designated DG263L is disclosed. Embodiments include the seeds of inbred rice line designated DG263L, the plants of inbred rice line designated DG263L, plant parts of inbred rice line designated DG263L, and methods for producing a rice plant produced by crossing rice DG263L with itself or with another rice variety. Embodiments include methods for producing a rice plant containing in its genetic material one or more genes or transgenes and the transgenic rice plants and plant parts produced by those methods. Embodiments also relate to rice cultivars, breeding cultivars, plant parts, and cells derived from inbred rice line designated DG263L, methods for producing other rice cultivars, lines or plant parts derived from inbred rice line designated DG263L, and the rice plants, varieties, and their parts derived from use of those methods. Embodiments further include hybrid rice seeds, plants, and plant parts produced by crossing DG263L with another rice cultivar.

Abstract: A light source fixing assembly includes an optical engine housing, a circuit board, a light emitting element, a flexible circuit board, a fixing element and an abutting element. The circuit board has a bearing surface, a first fixing region and a first conductive bonding region. The first bonding region and the light emitting element are on the bearing surface. The flexible circuit board is between the optical engine housing and the circuit board. The flexible circuit board has a first surface, a second surface opposite to the first surface, and a second fixing region. The second surface has a second bonding region. The fixing element fixes the circuit board and the flexible circuit board onto the optical engine housing. The abutting element abuts against the flexible circuit board and corresponds to the second bonding region, so that the first bonding region is electrically connected to the second bonding region.

Abstract: Various embodiments of systems, devices and methods for improving the accuracy of an analyte sensor and for detecting sensor fault conditions are disclosed. According to some embodiments, these systems, devices, and methods can utilize a first data collected by a glucose sensor and a second data collected by a secondary sensing element. In some embodiments, the secondary sensing element can be one of a lactate sensing element, a ketone sensing element, or a heart rate monitor, among others.

Abstract: A camera module includes an imaging lens assembly and an image sensor, wherein the image sensor is located on an image side of the imaging lens assembly. The imaging lens assembly has an optical axis and includes a plastic lens barrel and a plurality of plastic lens elements, wherein the plastic lens elements are disposed in the plastic lens barrel. The plastic lens barrel includes an object-side outer surface, a lens barrel minimum opening, an object-side outer inclined surface and a reversing inclined surface. The object-side outer surface is a surface of the plastic lens barrel facing towards an object side being closest to the object side and is annular. The reversing inclined surface expands from the lens barrel minimum opening to the image side, wherein a connecting position of the reversing inclined surface and the object-side outer inclined surface forms the lens barrel minimum opening.

Abstract: An electronic device is provided and includes a circuit board and a casing. The circuit board includes a plate body, a perforation and a ground wire. The perforation penetrates through the plate body, the ground wire is electrically coupled with the plate body and crosses over the perforation. The casing includes a bottom plate and a clamping structure. The clamping structure is disposed on the bottom plate and includes a first clamping part and a second clamping part. The circuit board is disposed in the casing, and the clamping structure penetrates through the plate body through the perforation, so that the circuit board is positioned on the casing, and the ground wire is clamped by the first clamping part and the second clamping part of the clamping structure. Consequently, the circuit board is grounded with the casing.