Abstract: An apparatus for placing preformed bags having an open end and a closed end over an insertion tube for inserting a bale therethrough and into the bag. A plurality of fingers are inserted into the bag open end and are extended for engaging the bag. The fingers and bag opening are traversed to the tube thereby inserting the tube end into the bag opening. The fingers are retracted and removed from the bag. The insertion tube is expanded thereby engaging the interior surface of the bag. Roller drive wheels are placed on the bag over the insertion tube and are rotatably driven and are traversed along the insertion tube for collecting the bag thereon. The roller drive wheels and the plurality of fingers are carried on a common assembly movable along the insertion tube.

Abstract: A chest freezer includes a plurality of insulated walls forming a compartment that includes an upwardly facing opening. A door is configured to selectively provide access to the compartment through the upwardly facing opening. A breaker strip forms at least a portion of an upper periphery of the compartment. A channel is formed in at least a portion of the breaker strip. The channel is configured to permit attachment of a storage container thereto. A cantilevered storage container for a chest freezer is also provided.

Abstract: An apparatus for protecting against environmental contamination at a drilling site is disclosed. The apparatus is used to form a perimeter around the drilling site, the interior of which is covered by a geomembrane. The portion of the geomembrane found along the perimeter is placed in the groove of the apparatus's base. A key block is then fit into the grove, thereby holding the geomembrane in place by the tension created between the base and the key block. At those perimeter locations that will be traversed by vehicles and equipment, two ramp pieces replace the key block in holding the geomembrane tight against the base.

Abstract: An apparatus for unfolding folded plastic film having a first side joined to a second side along a longitudinal folded edge for use in forming a packaging tube. The folded film travels through a slot and the folded sides are separated at their respective outer longitudinal edges. The longitudinal left side is conveyed toward and over a guide plate left side edge and then over a left form tube section. The longitudinal right side is conveyed toward and over a guide plate right side edge and then over a right form tube section. The longitudinal middle section including the longitudinal folded edge and part of both the first and second sides adjacent the longitudinal folded edge is conveyed toward and over guide plate angular edges and then onto a carrying surface.

Abstract: An apparatus for protecting against environmental contamination at a drilling site is disclosed. The apparatus is used to form a perimeter around the drilling site, the interior of which is covered by a geomembrane. The portion of the geomembrane found along the perimeter is placed in the groove of the apparatus's base. A key block is then fit into the grove, thereby holding the geomembrane in place by the tension created between the base and the key block. At those perimeter locations that will be traversed by vehicles and equipment, two ramp pieces replace the key block in holding the geomembrane tight against the base.

Abstract: Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted phenyl or optionally substituted pyridinyl, and R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

Abstract: An apparatus for closing and sealing a preformed polypropylene bag after a bale has been inserted therein as the bale and bag traverse along a longitudinal line of travel. Left and right rotatable side flaps fold the left and right bag closure flaps onto the bale. A bottom rotatable fold plate partially folds the bag bottom closure flap and a top fold bar is extended and folds the top bag closure flap onto the bale. The bottom fold plate then folds the bag bottom closure flap onto the bale. The top and bottom bag closure flaps are sandwiched between the rotatable side flaps and the bottom fold plate and over a slack bar therebetween forming a slack portion. A heating assembly directs heat to the slack portion melting the polypropylene and a press plate is extended to the slack melted portion thereby fusing the bag closure flaps together.

Abstract: An apparatus for separating the bag walls of preformed bags having an open end and a closed end for use in an apparatus for enveloping bales of material. The bag walls are initially adjacent one another. Vacuum and grip pin assemblies are provided on jaws which are movable between retracted and closed positions. The jaws are closed onto the bag walls and a vacuum is applied to vacuum inlet openings drawing the bag walls thereto. Preferably, the jaws are partially separated and then a grip pin is extended adjacent the vacuum inlet openings thereby piercing and securely gripping the walls. The jaws are then retracted thereby fully separating the bag walls and opening the bag. Preferably, the vacuum inlet openings are saddle shaped having a rim defining aligned raised sides and aligned lowered sides therebetween, and the grip pin extends along the aligned raised sides.

Abstract: An apparatus for placing preformed bags having an open end and a closed end over an insertion tube for inserting a bale therethrough and into the bag. A plurality of fingers are inserted into the bag open end and are extended for engaging the bag. The fingers and bag opening are traversed to the tube thereby inserting the tube end into the bag opening. The fingers are retracted and removed from the bag. The insertion tube is expanded thereby engaging the interior surface of the bag. Roller drive wheels are placed on the bag over the insertion tube and are rotatably driven and are traversed along the insertion tube for collecting the bag thereon. The roller drive wheels and the plurality of fingers are carried on a common assembly movable along the insertion tube.

Abstract: A continuous web of closed, preformed end-to-end bags for enclosing bales of material are made by forming an elongate sheet into a helix tube, flattening the tube into first and second elongate bag walls and securing the bag walls at closure seams located along the flattened helix tube. The helix tube is formed by nesting the elongate sheet side edges into U-shapes and sewing. The bag walls are secured to one another by nesting them into U-shapes and sewing. Bales are enveloped by severing the web and thereby providing a bag with an open end, separating the bag walls, inserting a bale therein, closing the bag and severing from the remaining web. Each bag is located along the web with a pair of sensors which provide a locating signal responsive to the bag closure seams.

Abstract: Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Abstract: Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted phenyl or optionally substituted pyridinyl, and R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

Abstract: Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Abstract: An apparatus for protecting against environmental contamination at a drilling site is disclosed. The apparatus is used to form a perimeter around the drilling site, the interior of which is covered by a geomembrane. The portion of the geomembrane found along the perimeter is placed in the groove of the apparatus's base. A key block is then fit into the grove, thereby holding the geomembrane in place by the tension created between the base and the key block. At those perimeter locations that will be traversed by vehicles and equipment, two ramp pieces replace the key block in holding the geomembrane tight against the base.

Abstract: The invention is directed to Compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.

Abstract: An illumination balloon which has an inflatable bladder surrounding an assembly that includes a frame comprised of hollow tubes, lighting sources, and mechanical fan for inflating said bladder. The lighting sources are staggered along the frame so that each is unimpeded from the fixtures and bulbs of the other lighting sources. The mechanical fan does require a transformer to step up or step down the voltage received from an external power supply. Wiring to energize the lighting sources and mechanical fan are threaded through the hollow tubes of the frame.

Abstract: A bulk material leveling and volumetric measuring and feeding apparatus includes a conveyor for transporting bulk material from a hopper to a leveling assembly. The leveling assembly includes a pair of augers located perpendicular to the conveyor and with the auger terminal ends at a desired height from the conveyor. Side walls are provided parallel to the conveyor direction of travel and extend up to the auger terminal ends. Each auger is positioned within a semicircular longitudinal channel of a trough. Bulk material being transported and which is located above the augers terminal ends is lifted by the augers and thrown back towards the hopper. Thus, bulk material being transported under and beyond the leveling assembly is maintained at a desired depth. By monitoring and/or controlling the conveyor speed and the depth of the transported bulk material, the volumetric feed rate and total volume of transported material can be determined and/or controlled.

Abstract: Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Abstract: Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted phenyl or optionally substituted pyridinyl, and R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

Abstract: A joining apparatus and methods wherein, after plastic film is formed into a variable size tube for receiving therein and enveloping corresponding variable size large articles such as bales of cotton, trash, cloth, etc., the joining apparatus joins an overlap region of the plastic film tube for effectively sealing and creating the plastic film tube. The joining apparatus includes an inner shoe located inside the formed tube. The overlap region slides over the inside shoe as the tube is formed. An outside shoe is moveable between an idle position away from and an operative position adjacent to the inside shoe. When in its operative position, the overlap region is sandwiched between the outside and inside shoes and heated air is provided under pressure through a groove on the outside shoe and onto the overlap region for effectively heating and joining the overlapped plastic sheets.