Abstract: The invention features a gastrointestinal device and methods of use thereof for the treatment of metabolic disorders. The gastrointestinal device features disintegrable sleeve configured to fit within a patient's duodenum and to carry fluid (e.g., liquid or semisolid material, for example, chyme and digestive secretions) from its proximal end to its distal end.

Abstract: Molecular rotational resonance (MRR) spectroscopy can be used to characterize neutral, gas-phase molecules with very fine spectral resolution. Typically, the analyte molecules are placed in solution, which is heated initially to evaporate the solvent, then heated more to volatilize the analyte. Unfortunately, this approach does not always work well for analytes with low volatilities or susceptibility to thermal degradation. These analytes can be volatilized instead using laser-induced acoustic desorption (LIAD), flash vaporization, or nebulization. In LIAD, the analyte is dried onto a metal foil, which is illuminated by a laser. The laser beam generates an acoustic wave in the metal foil that shakes off the analyte. In flash vaporization, a small amount of liquid analyte drips onto a very hot surface, where it vaporizes too quickly to degrade. And in nebulization, a nebulizer pumps a fine spray of analyte into a heated transfer tube, where the solvent evaporates.

Abstract: There is provided a method of measuring liquid volume in a sealed container of a breast pump of known volume comprising liquid and gas. The method includes a measurement phase, measuring the volume of gas in the container by changing a first parameter of the gas by a known amount. The method also includes measuring a change in a second parameter of the gas; calculating the volume of gas in the container using the measured change and a predetermined operation equation; and determining the volume of liquid in the container based on the calculation.

Abstract: An in-bra wearable breast pump is provided. The breast pump includes an air pump system for generating a base level vacuum and a pumping vacuum, a breast shield for receiving a user's breast and having a first side and a second side, a first channel for drawing the base level vacuum on the first side of the breast shield, and a second channel for drawing the pumping vacuum on the second side of the breast shield.

Abstract: An incisionless fully endoscopic method of reducing the capacity of the stomach is provided to surgically treat obesity. The method is directed to endoluminal tissue approximation of a portion of the stomach, including at least a portion of the greater curvature thereof. The method includes a pattern of stitching in which a portion of the stomach is closed off. One stitching pattern causes the lateral portion of the stomach to be drawn to reduce the usable volume of the stomach while maintaining a pathway from the esophagus to the pylorus. As the stitching pattern advances, the fundus is automatically drawn downward so that it may be endoscopically approached for stitching in a facilitated manner According to another aspect of the invention, another stitching pattern extends from the antrum to the fundus between the anterior and posterior portions of the stomach.

Abstract: An incisionless fully endoscopic method of reducing the capacity of the stomach is provided to surgically treat obesity. The method is directed to endoluminal tissue approximation of a portion of the stomach, including at least a portion of the greater curvature thereof. The method includes a pattern of stitching in which a portion of the stomach is closed off. One stitching pattern causes the lateral portion of the stomach to be drawn to reduce the usable volume of the stomach while maintaining a pathway from the esophagus to the pylorus. As the stitching pattern advances, the fundus is automatically drawn downward so that it may be endoscopically approached for stitching in a facilitated manner. According to another aspect of the invention, another stitching pattern extends from the antrum to the fundus between the anterior and posterior portions of the stomach.

Abstract: A stent for repairing post-anastomasis (e.g., bariatric) surgery leaks is formed by an elongated tube having a proximal flare-shaped flange, an enlarged middle section, and a distal flare-shaped flange, where an exterior surface of the elongated tube is substantially covered with a polymer.

Abstract: A gastrointestinal device and methods of use thereof for the treatment of metabolic disorders is provided. The gastrointestinal device features disintegrable sleeve configured to fit within a patient's duodenum and to carry fluid (e.g., liquid or semisolid material, for example, chyme and digestive secretions) from its proximal end to its distal end.

Abstract: One or more techniques and/or systems are disclosed for automatically obtaining a profile for a set of accelerator pedal position sensors in a target vehicle. The profile can comprise a correlation of the position of the pedal to an output signal for one or more sensor in the set of sensors. A pedal position sensor signal reader can be used to automatically detect signals from one or more pedal position sensor in the target vehicle's accelerator pedal, while the pedal is released, depressed, and moving between the released and depressed positions. A pedal profile can be automatically generated using the output signals and corresponding pedal positions. Obtained data can be used to program a speed control device for the target vehicle. Correlated output can be used to adjust the speed of the vehicle by sending an emulated signal to the ECM, which may adjust the speed control system.

Abstract: The invention features delivery systems for delivering a gastrointestinal device into the gastrointestinal tract of a patient and anchoring the gastrointestinal device with an anchor (e.g., a disintegrable anchor). Also provided are methods of delivering such gastrointestinal devices using the delivery systems described herein. The methods and delivery systems of the invention can be used for treatment of metabolic diseases, such as type 2 diabetes, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), obesity, and related comorbidities thereof.

Abstract: The invention features a gastrointestinal device and methods of use thereof for the treatment of metabolic disorders. The gastrointestinal device features disintegrable sleeve configured to fit within a patient's duodenum and to carry fluid (e.g., liquid or semisolid material, for example, chyme and digestive secretions) from its proximal end to its distal end.

Abstract: The invention features a gastrointestinal anchoring system for securing a gastrointestinal device within the gastrointestinal tract of a patient. Further provided are methods of using the anchoring system to secure a gastrointestinal device within the gastrointestinal tract of a patient and methods of treatment using the anchoring system of the invention to secure a gastrointestinal device of the invention to a luminal wall within a patient's gastrointestinal tract.

Abstract: One or more techniques and/or systems are disclosed for automatically obtaining a profile for a set of accelerator pedal position sensors in a target vehicle. The profile can comprise a correlation of the position of the pedal to an output signal for one or more sensor in the set of sensors. A pedal position sensor signal reader can be used to automatically detect signals from one or more pedal position sensor in the target vehicle's accelerator pedal, while the pedal is released, depressed, and moving between the released and depressed positions. A pedal profile can be automatically generated using the output signals and corresponding pedal positions. Obtained data can be used to program a speed control device for the target vehicle. Correlated output can be used to adjust the speed of the vehicle by sending an emulated signal to the ECM, which may adjust the speed control system.

Abstract: A stent for repairing post-anastomasis (e.g., bariatric) surgery leaks is formed by an elongated tube having a proximal flare-shaped flange, an enlarged middle section, and a distal flare-shaped flange, where an exterior surface of the elongated tube is substantially covered with a polymer.

Abstract: A stent for repairing post-anastomasis (e.g., bariatric) surgery leaks is formed by an elongated tube having a proximal flare-shaped flange, an enlarged middle section, and a distal flare-shaped flange, where an exterior surface of the elongated tube is substantially covered with a polymer.

Abstract: An incisionless fully endoscopic method of reducing the capacity of the stomach is provided to surgically treat obesity. The method is directed to endoluminal tissue approximation of a portion of the stomach, including at least a portion of the greater curvature thereof. The method includes a pattern of stitching in which a portion of the stomach is closed off. One stitching pattern causes the lateral portion of the stomach to be drawn to reduce the usable volume of the stomach while maintaining a pathway from the esophagus to the pylorus. As the stitching pattern advances, the fundus is automatically drawn downward so that it may be endoscopically approached for stitching in a facilitated manner. According to another aspect of the invention, another stitching pattern extends from the antrum to the fundus between the anterior and posterior portions of the stomach.

Abstract: Example methods, apparatuses, and systems (e.g., machines) are presented for a gamification platform that is the first automated, machine-based system to seamlessly integrate and deliver personalized remediation, centralized learning resources, experiential learning labs, peer and mentor collaboration, immersive scenario-based story, gamified scoring, and real-time heuristics to a user in a learning and training environment. In some embodiments, the gamification platform may be configured to ingest pre-existing training material or other teaching curricula and create an interactive gaming program around the exercise of the training material by a user.

Abstract: An aircraft monitoring system includes multiple wireless aircraft sensors and multiple meta sensors mounted on-board an aircraft. Each wireless aircraft sensor is configured to sense an aircraft parameter. Each meta sensor is associated with an aircraft sensor and is configured to determine a location or orientation on the aircraft of the aircraft sensor. A data acquisition system mounted on-board the aircraft and connected to the multiple aircraft sensors and the multiple meta sensors can perform aircraft monitoring operations based on the sensed aircraft parameters and on a location or orientation of the aircraft sensors.

Abstract: Interaction of a user with external data sources related to the research and analysis of terms and content for improved indexing by search engines may be provided. One or more elements of the content may be used to return an analysis of those elements to the user within the experience of a word processing application environment. Systems and methods also may be provided for determining the relative competition of a term or terms to quantitatively derive the number of pages within a corpus that may be actively engaged to improve the indexing of the pages by information retrieval systems, such as search engines. Systems and methods may be further provided for determining the relative ranking of a term or terms based on the frequency and placement of the term or terms within a structured page.