Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: Methods, kits, and compositions are provided herein that can be used to treat hematopoietic disorders using an anti-CD47 agent such as an antibody and a hypomethylating agent, such as azacitidine.

Abstract: Provided herein are hydantoin compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.

Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: Described herein, inter alia, are compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.

Abstract: Provided herein are compounds and pharmaceutical compositions including the compound having a formula: These compounds are androgen receptor modulators useful for the treatment of androgen receptor-associated conditions.

Abstract: A backlight assembly includes a substantially planar light guide defining an upper, lower, and first side surface. A first plurality of LEDs is positioned to emit light into the lower surface. A NVIS filter is placed adjacent to, and a second plurality of LEDs is positioned near to, the first side surface. A directing element extends between the second plurality of LEDs and the NVIS filter and directs the emitted light from the second plurality of LEDs through the NVIS filter and into the light guide. The NVIS filter extends substantially perpendicular from a support structure associated with the light guide.

Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: A backlight assembly includes a substantially planar light guide defining an upper, lower, and first side surface. A first plurality of LEDs is positioned to emit light into the lower surface. A NVIS filter is placed adjacent to, and a second plurality of LEDs is positioned near to, the first side surface. A directing element extends between the second plurality of LEDs and the NVIS filter and directs the emitted light from the second plurality of LEDs through the NVIS filter and into the light guide. The NVIS filter extends substantially perpendicular from a support structure associated with the light guide.

Abstract: An electronic display assembly having forced-air cooling. A thermally conductive plate or a thermally conductive backlight surface is located behind an electronic display of the electronic display assembly and within a housing thereof such that a gap is formed between the plate or backlight surface and an adjacent wall of the housing. External cooling air may be caused to flow in a top-to-bottom direction through the gap in order to remove heat from the electronic display that has been conductively transferred to the gap. A plurality of ribs may be placed within the gap and in thermal communication with the electronic display to enhance the conductive transfer of heat from the electronic display.

Abstract: A backlight assembly includes a substantially planar light guide defining an upper surface, a lower surface, and a side surface. A first plurality of LEDs is positioned below the lower surface of the light guide and oriented to direct the light emitted therefrom into the lower surface. A NVIS filter is placed adjacent to the side surface and a second plurality of LEDs is positioned near the side surface. A separating element extends between the first and second plurality of LEDs. A directing element extends between the second plurality of LEDs and the NVIS filter to direct the emitted light from the second plurality of LEDs through the NVIS filter and into the light guide.

Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: A backlight assembly includes a substantially planar light guide defining an upper surface, a lower surface, and a side surface. A first plurality of LEDs is positioned below the lower surface of the light guide and oriented to direct the light emitted therefrom into the lower surface. A NVIS filter is placed adjacent to the side surface and a second plurality of LEDs is positioned near the side surface. A separating element extends between the first and second plurality of LEDs. A directing element extends between the second plurality of LEDs and the NVIS filter to direct the emitted light from the second plurality of LEDs through the NVIS filter and into the light guide.

Abstract: Exemplary embodiments provide an electronic display assembly comprising a liquid crystal layer and a light guide positioned behind the liquid crystal layer. The light guide preferably includes a light emission surface and a light-collecting portion opposing the light emission surface. A pair of opposing side portions may define the periphery of the light guide. A first plurality of LEDs are placed so as to direct the emitted light into the light-collecting portion. An NVIS filter is preferably placed adjacent to at least one of the side portions. A second plurality of LEDs are placed to direct the emitted light through the NVIS filter and into a side portion of the light guide. Alternative embodiments can contain directing elements to direct the light from the second plurality of LEDs into the edge portions of the light guide.

Abstract: Described herein, inter alia, are compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.

Abstract: Described herein, inter alia, are compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.

Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: An electronic display assembly having forced-air cooling. A thermally conductive plate or a thermally conductive backlight surface is located behind an electronic display of the electronic display assembly and within a housing thereof such that a gap is formed between the plate or backlight surface and an adjacent wall of the housing. External cooling air may be caused to flow in a top-to-bottom direction through the gap in order to remove heat from the electronic display that has been conductively transferred to the gap. A plurality of ribs may be placed within the gap and in thermal communication with the electronic display to enhance the conductive transfer of heat from the electronic display.

Abstract: An electronic display which can be mounted above a paved surface in an outdoor environment. A surface or plate is placed behind the electronic display to define a gap where cooling air can be drawn through said gap in order to cool the electronic display. A plurality of ribs may be placed within the gap and in thermal communication with the electronic display. The density of the ribs may be varied according to the inlet and exhaust openings for the cooling air. The ribs may be placed at a higher density near the exhaust to account for the increase in temperature of the cooling air as it travels through the gap.