Abstract: The present disclosure is directed to articles that include one or more coated fiber(s) (i.e., fiber(s) with a cured coating disposed thereon), where the coating includes a matrix of crosslinked polymers and optionally a colorant (e.g., pigment particles or dye or both). The cured coating is a product of crosslinking a coating composition including uncrosslinked polymers (e.g., a dispersion of uncrosslinked polymers in a carrier, wherein the uncrosslinked polymers are crosslinked to form the matrix of crosslinked polymers). The present disclosure is also directed to articles including the coated fibers, methods of forming the coated fibers and articles, and methods of making articles including the coated fibers.

Abstract: In some implementations, a downhole oil-water separation (DOWS) assembly may be configured to be disposed downhole in a well. The DOWS assembly may include a DOWS device configured to operate on fluids in the DOWS assembly. The DOWS assembly also may include a controller configured to determine an orientation of the DOWS device and to cause a change to the orientation of the DOWS device.

Abstract: An integrated platform system that employ a series of machine learning techniques and prediction and detection units that can process input data and extract and generate meaningful insights and predictions therefrom. The system integrates together multiple different data storage types and applications that generates data of different types, and an associated processing system for processing the different data types, store the data in a common data model to normalize the data, determine the data lineage of the data, and then process the data using different types of techniques. The data can also be processed by a prediction unit for generating meaningful insights and predictions or by an anomaly detection unit for detecting one or more anomalies in the data.

Abstract: A sole structure for an article of footwear includes a baseplate defining a ground-contacting surface of the sole structure and at least two ground-engaging members extending from the ground-contacting surface. The at least two ground-engaging members including a first portion and a second portion, the first portions of the ground-engaging members being connected to one another by a bridge formed separately from the baseplate.

Abstract: A method for forming a plate includes attaching a first strand portion to a flexible substrate to form a first layer on the substrate and positioning a second strand portion on the first layer to form a second layer on the first layer in a plurality of discrete regions on the substrate. The method also includes positioning a plurality of traction elements into corresponding cavities formed into a first mold surface and positioning the substrate on the first mold surface to change a shape of the substrate. At least one of heat and pressure is applied to the first strand portion, the second strand portion, the substrate, and the traction elements to conform the substrate to the shape of the first mold surface and form the traction elements into the substrate at each of the discrete regions. The method also includes incorporating the substrate into an article of footwear.

Abstract: A method of forming a plate for an article of footwear is disclosed. The method includes applying a first strand portion to a base layer including positioning adjacent segments of the first strand portion to form a first layer on the base layer. The adjacent segments of the first strand portion having a greater density across a width of the plate between a medial side and a lateral side at a forefoot region of the plate than at a midfoot region of the plate and at a heel region of the plate. The method also includes applying at least one of heat and pressure to the first strand portion and to the base layer to conform the first strand portion and the base layer to a predetermined shape.

Abstract: A plate for an article of footwear includes a substrate, a first strand portion attached to the substrate via first stitching, and a second strand portion disposed on the first layer. The first strand portion includes first segments that each extend between two different locations along the substrate to form a first layer on the substrate. The second strand portion includes second segments that each extend between two different locations along the substrate to form a second layer on the first layer.

Abstract: The invention relates to the field of antibacterial polypeptides, specifically to the field of antibacterial polypeptides having lytic activity for Staphylococcus. The invention relates to a novel chimeric endolysin polypeptide specifically targeting a Staphylococcus cell. The invention further relates to the use of said chimeric endolysin polypeptide as a disinfectant, as an antimicrobial cosmetic, for detection, such as in a diagnostic application and for medical use, such as for treating an individual suffering from a condition associated with a Staphylococcus infection.

Abstract: Provided is a downhole tool, a y-block, a well system, and a method for forming a well system. The downhole tool, in one aspect, includes a bottom hole assembly (BHA) having an uphole end and a downhole end, and a shroud positioned around and proximate the downhole end of the BHA, the shroud operable to slide relative to the BHA. The downhole tool, in this aspect, may further include one or more shear features coupling the shroud to the downhole end of the BHA.

Abstract: A sole structure for an article of footwear includes a baseplate defining a ground-contacting surface of the sole structure and at least two ground-engaging members extending from the ground-contacting surface. The at least two ground-engaging members including a first portion and a second portion, the first portions of the ground-engaging members being connected to one another by a bridge formed separately from the baseplate.

Abstract: The present invention relates to new and improved methods for the use of Compound 1 in the treatment of inflammatory diseases and/or diseases associated with hypersecretion of IFN? and/or interferons (“interferonopathies”, especially type I interferonopathies), IL-12 and/or IL-23, and pharmaceutical unit dosage compositions comprising compound 1 for use therein.

Abstract: The invention relates to the field of medicine, specifically to the field of treatment of conditions associated with Staphylococcus infection. The invention relates to a novel endolysin polypeptide specifically targeting a bacterial Staphylococcus cell. The invention further relates to said endolysin polypeptide for medical use, preferably for treating an individual suffering from a condition associated with Staphylococcus infection.

Abstract: The invention relates to the field of antibacterial polypeptides, specifically to the field of antibacterial polypeptides having lytic activity for Staphylococcus. The invention relates to a novel chimeric endolysin polypeptide specifically targeting a Staphylococcus cell. The invention further relates to the use of said chimeric endolysin polypeptide as a disinfectant, as an antimicrobial cosmetic, for detection, such as in a diagnostic application and for medical use, such as for treating an individual suffering from a condition associated with a Staphylococcus infection.

Abstract: The invention relates to the field of medicine, specifically to the field of treatment of conditions associated with Staphylococcus infection. The invention relates to a novel endolysin polypeptide specifically targeting a bacterial Staphylococcus cell. The invention further relates to said endolysin polypeptide for medical use, preferably for treating an individual suffering from a condition associated with Staphylococcus infection.

Abstract: A multilateral junction comprising a y-block, lateral legs, and a transition sub for use in downhole well environments. The y-block includes a main bore and lateral bores with main bore and the lateral bores having threaded interfaces. The transition sub also includes lateral bores with threaded interfaces for receiving the lateral legs that also have threaded interfaces. The threaded interfaces of the lateral bore of the y-block has a less number of threads than the threaded interfaces of the lateral bores of the transition sub. The lateral leg includes another threaded interface that couples with the threaded interface of the lateral bore. Another end of each lateral leg includes an interface, e.g. a threaded interface, which couples with an interface of a transition sub. The main bore has an internal diameter that is greater than the internal diameter of the lateral bore.

Abstract: Provided is a multilateral leg bore, a multilateral junction, and a well system. The multilateral leg bore, in one aspect, includes a unitary housing having a first end and a second opposing end defining a length (L). In accordance with this aspect, the multilateral junction includes three or more bores formed in the housing and extending along the length (L).

Abstract: A method of forming a composite article includes constructing a preform having a strand layer including an interior portion and a peripheral portion surrounding the interior portion. The strand layer includes a plurality of strand segments traversing the interior portion and defining a first strand segment population density and a second strand segment population density. The preform is inserted into the mold cavity so that the interior portion of the preform is received in a molding region of the mold cavity. The molding region has a first thickness corresponding to the first strand segment population density and a second thickness corresponding to the second strand segment population density. Following the inserting, the mold is closed and the interior portion of the preform is compressed within the molding region. In the closed mold, the peripheral portion of the strand layer may be maintained in a loose state within the relief region.

Abstract: A sole structure for an article of footwear is described. In one example, the sole structure includes first and second foam components and one or more mesh components, e.g., a mesh textile component. The first foam component includes first and second opposing sides, and the second foam component includes first and second opposing sides. The first and second foam components form a stack in the sole structure. The mesh components, e.g., a mesh textile component, are positioned in the stack between and bonded to the second side of the first foam component and the first side of the second foam component. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: A method of forming a plate for an article of footwear is disclosed. The method includes applying a first strand portion to a base layer including positioning adjacent segments of the first strand portion to form a first layer on the base layer. The adjacent segments of the first strand portion having a greater density across a width of the plate between a medial side and a lateral side at a midfoot region of the plate than at a forefoot region of the plate and at a heel region of the plate. The method also includes applying at least one of heat and pressure to the first strand portion and to the base layer to conform the first strand portion and the base layer to a predetermined shape.

Abstract: The present invention relates to certain substituted AHR agonist compounds, to pharmaceutical compositions comprising the compounds and to methods of using the compounds to treat immune-mediated diseases.