Abstract: A method for controlling properties of a medical implant includes locating the medical implant in an interspinous area between two spinal processes of a person. The medical implant is coupled to a container via a conduit. A fluid is received in an interior of the container in fluid communication with the conduit. The fluid flows from the container toward the implant having an interior configured to receive the fluid. A pressure sensor is coupled to the interior of the container and/or an interior of the conduit. An internal pressure is determined of the interior of the interior of the container and/or the interior of the conduit by the sensor. The flow of the fluid is regulated to the interior of the implant to regulate a volume of the implant based on the internal pressure and a medical condition of the person.

Abstract: An electrical contact configuration having a test contact point and a contacting element belonging to a testing device for manually touch-contacting the test contact point. The test contact point is a recess, and the contacting element has a contact region producing at least one line contact with the recess.

Abstract: A method of growing a thin film comprises growing a thin film by conformally forming at least one layer over a substrate having structures extending from a surface of the substrate, whereby the or each layer is formed over the surface of the substrate and over the structures extending from the surface. The thickness of the conformal layer, or the sum of the thicknesses of the conformal layers, is at least half the average spacing of the structures, and; at least one of the height of the structures, the average spacing of the structures and the size of the smallest dimension of the structures is set so as to provide an enhanced growth rate for the or each conformal layer (compared to the growth rate over a planar substrate).

Abstract: The invention relates to an insulation displacement connection and to a method for connecting two components, especially for high current applications, said connection comprising a first insulation displacement element, which is fixed to a first component, and a second insulation displacement element, which is fixed to a second component. The two insulation displacement elements can be inserted into each other in the direction of assembly, the first and/or second insulation displacement element being fixed to the first and/or second component in such a way that the insulation displacement element is moveably arranged in a plane transversal to the direction of assembly.

Abstract: Systems and methods of estimating a fluid injector tip temperature. A controller having a processor and a memory supplies a current to a coil of a fluid injector, a resistance of the coil is measured when the current is supplied to the coil, a coil temperature is determined based on the measured resistance, and a tip temperature of a fluid injector tip is estimated based on the determined coil temperature.

Abstract: The invention relates to an insulation displacement connection and to a method for connecting two components, especially for high current applications, said connection comprising a first insulation displacement element, which is fixed to a first component, and a second insulation displacement element, which is fixed to a second component. The two insulation displacement elements can be inserted into each other in the direction of assembly, the first and/or second insulation displacement element being fixed to the first and/or second component in such a way that the insulation displacement element is moveably arranged in a plane transversal to the direction of assembly.

Abstract: An electrical contact configuration having a test contact point and a contacting element belonging to a testing device for manually touch-contacting the test contact point. The test contact point is a recess, and the contacting element has a contact region producing at least one line contact with the recess.

Abstract: A modified L-nucleic acid, containing an L-nucleic acid part conjugated to a non-L-nucleic acid part is described. The conjugate has extended retention time in and demonstrates a delayed elimination from an organism.

Abstract: The present invention is related to a method for the detection of a nucleic acid molecule comprising at least a strand comprising a sequence of nucleotides in a sample, whereby the method comprises the following steps: i) providing a sample containing the nucleic acid molecule; j) providing a capture probe, whereby the capture probe is at least partially complementary to a part of the nucleic acid molecule; k) allowing the capture probe to react with the nucleic acid molecule or a part thereof; and d) detecting whether or not the capture probe is hybridized to the nucleic acid molecule or part thereof.

Abstract: The present invention relates to a modified L-nucleic acid, comprising a L-nucleic acid part and a non-L-nucleic acid part, whereby the L-nucleic acid part is conjugated to the non-L-nucleic acid part and the conjugation of the L-nucleic acid part with the non-L-nucleic acid past leads to a slowed elimination out of the organism, in comparison with a L-nucleic acid which only comprises the L-nucleic acid part, said L-nucleic acid part being a spiegelmer.

Abstract: A method of fabricating a device structure, comprises: forming an insulating layer (3b) over a first set of devices disposed over a substrate (3); forming one or more vias in the insulating layer; disposing a second set of devices (6) over the insulating layer, wherein devices of the second set comprise respective electrical contacts (6a) and are disposed over the insulating layer (3b) such that a side on which a contact (6a) can be accessed faces the substrate (3); and forming one or more electrical contacts between the first set of devices and the second set of devices (6) through the via(s). The second set of devices and at least one via are positioned such that one or more of the vias lies at least partially within the footprint of two devices, each belonging to a different device layer.

Abstract: Disclosed is a method for determining a pixel gray scale value image, particularly for a multi-dimensional image system. According to said method a first modulation signal (M1) which is emitted at the emitting end and is reflected on an object that is to be recorded is correlated with a second modulation signal (M2) and is recorded at the receiving end based on at least two correlation signals (Ua, Ub or Ia, Ib) that are proportional to the respective received first modulation signal (M1). One of said modulation signals (M1, M2) is phase shifted in several phase steps (?k) at the emitting or receiving end and a differential signal (D) is determined for each phase step (?k) based on the correlation signals (Ua, Ub or Ia, Ib,) and a pixel gray scale value (PGray) is determined based on said difference signal (D) independently of interfering signals.

Abstract: A method for controlling properties of a medical implant includes locating the medical implant in an interspinous area between two spinal processes of a person. The medical implant is coupled to a container via a conduit. A fluid is received in an interior of the container in fluid communication with the conduit. The fluid flows from the container toward the implant having an interior configured to receive the fluid. A pressure sensor is coupled to the interior of the container and/or an interior of the conduit. An internal pressure is determined of the interior of the interior of the container and/or the interior of the conduit by the sensor. The flow of the fluid is regulated to the interior of the implant to regulate a volume of the implant based on the internal pressure and a medical condition of the person.

Abstract: Embodiments of the invention relate to a vector system that allows one to induce expression of therapeutically relevant genes in mammalian cells. Such a vector system may be useful for medicine and in the pharmaceutical industry. A vector comprises base structures suitable for expression in mammalian cells as well as either the whole of or parts of the gene promoter of human Major Vault Protein (MVP), also known as LRP (Lung Resistance Protein) as well as a gene encoding a therapeutic protein or non-translated RNA. As the MVP promoter is inducible by therapy (for example, but not limited to, chemotherapy or hyperthermia), the vector system provides combinations of therapeutic methods with gene therapy in a controlled fashion, resulting in more efficient treatment of tumor diseases.

Abstract: Techniques are provided for enabling execution of a process employing a cache. Method steps can include obtaining a first probability of accessing a given artifact in a state Si, obtaining a second probability of using a predicate from a current state Sc in the state Si, determining a benefit of prefetching the given artifact using the predicate based on at least the first probability and the second probability, and whether and/or when a cache replacement should be conducted, based at least on the benefit determined.

Abstract: An embodiment of the present invention provides a computer system comprising a first memory and a second memory, where the first memory is substantially faster than second and that performs a method includes steps of: receiving requests for blocks from scan processes; serializing requests for blocks with a request queue; inspecting requests, with a request handler process, R, for blocks and determining whether the requests can be fulfilled from the first memory, if possible; and using an interface for: getting a next data item not yet processed by a calling process, starting a new one-time table access operation, and ending one-time table access operation.

Abstract: Methods and apparatus are provided for incremental approximate nearest neighbor searching. An approximate nearest neighbor is incrementally retrieved from a data set having a plurality of objects and cells of objects in a hierarchical organization based on a query object. The present invention maintains an object priority queue to organize the objects based on a distance to the query object and a cell priority queue to organize the cells of objects based on a distance to the query object. The next approximate nearest neighbor is incrementally retrieved based on a state of one or more of the object priority queue and the cell priority queue.

Abstract: A method of utilizing one or more hints for query processing over a hierarchical tagged data structure having a plurality of nodes in a computing system having memory, the hint being positive if there is a tag accessible in top-down traversal from a child node, and otherwise negative. For each tag in the data structure, the method calculates a bitmap for a current node with all bits set to 1 and for each child node, followed by AND-ing all child bitmaps and setting a bit corresponding to a tag ID of a current tag to zero if such current tag exists. The method further sets a bit of a current tag to 0, calculates a plurality of possible non-redundant hints for each child node, and refreshes a hint list.

Abstract: The invention relates to a method for calibrating 3D image sensors. Work tolerances, temperature variations and aging processes result in that the various pixels in a receiving array deviate from one another to different degrees. The aim of the invention is therefore to calibrate the entire receiving array with respect to every pixel. During operation of the 3D image sensor there is usually no reference scene available with which every pixel could be calibrated based on known phase relations. According to the invention, the entire receiving array is illuminated at defined intervals exclusively with one modulated light source. Alternatively, the emitted light source can be used via a deflection device. Two different distances can be simulated by carrying out two calibrating measurements with different phase relations between emitted and received signal, thereby making it possible to detect distance-related errors for every pixel individually.

Abstract: The invention relates to a method for detecting properties of a digital-analog mixed signal system (1) by formally verifying a digital substitution system (20). Component parameters and environment parameters are depicted as additional signals in the digital substitution model (substitution model, 20) for the analog components, and the analog part of the system is divided (90) into time-independent and linear time-dependent subsystems. The time-independent subsystems are regarded as stateless and are converted by combinatorial logic and the linear time-dependent subsystems for time-discretization while being substituted by finite automations. Despite the digitizing errors, it is possible to reliably draw conclusions about the original system from the verification results of the substitution model.