Abstract: A system for categorizing, visualizing, and recommending Cannabis products based on objective data of the chemical composition of products is described. This system allows Cannabis products to be visualized and compared based on their chemical composition, even by laypeople with little or no knowledge of the underlying objective data. A recommendation system is built upon this which can recommend products for consumption, including a user interface for receiving user input, which includes at least one of demographic data, desired level of psychoactivity, or prior experience with the product, a merchant interface for receiving merchant input, including at least one of general data descriptive of the regulated product, lab data descriptive of the regulated products chemical composition, and user data descriptive of subjective effects of the regulated product on a user; and a decision engine making a recommendation of product according to correlation of the lab data with the user data.

Abstract: A multipurpose connector for connecting a multiplicity of lines of an aircraft monument. The multipurpose connector comprises a base bracket, a system connector plate configured to receive a multiplicity of first line adapters, a monument connector plate configured to receive at least one second line adapter, and a movement device configured to move the system connector plate relative to the base bracket and the monument connector plate between an open position and a closed position. The system connector plate is, in the closed position, arranged relative to the monument connector plate such that the at least one second line adapter of the monument connector plate is operatively connected to an associated first line adapter of the system connector plate, and, in the open position of the system connector plate, the multiplicity of first line adapters and the at least one second line adapter are detached from one another.

Abstract: The present invention relates to a method for obtaining a neural micros-phere, comprising the steps of culturing pluripotent stem cells (PSCs), differentiating the PSCs into neural stem precursor blast cells, aggregating the neural stem precursor blast cells to form a neural microsphere, allowing the neural stem precursor blast cells of the neural microsphere to further mature, and collecting the neural microsphere.

Abstract: An unmanned ground-based hygiene maintenance vehicle, UGV, includes a housing with a base plate, top plate and housing side wall substantially perpendicular to the base plate. Arranged in the housing is at least one wheel drive coupled to at least one wheel in a recess in the base plate. The UGV includes sensors for sensing the environment of the UGV, and a controller for autonomous location and navigation of the UGV based on sensing parameters of the sensors. The UGV includes an articulated robot arm on the top plate of the housing and to support a hygiene maintenance tool. The UGV includes at least one load-receiving element coupled to the housing side wall and extending outwards from the housing side wall, wherein the load-receiving element includes a load support surface for supporting a hygiene maintenance tool supply module with respect to a vertical direction extending transverse to the base plate.

Abstract: An unmanned ground-based transport vehicle, UGV, includes a housing, having a base plate and at least one housing side wall substantially perpendicular to the base plate. Arranged in the housing is at least one wheel drive, which is coupled to at least one wheel. The wheel is arranged in a recess in the base plate. The UGV further includes sensors for sensing the environment of the UGV, and a controller for autonomous location and navigation of the UGV on the basis of sensing parameters of the sensors. The UGV includes at least one load-receiving element coupled to the housing side wall and extending outwards from the housing side wall, wherein the load-receiving element includes a load support surface for supporting an item with respect to a vertical direction which extends transverse to the base plate.

Abstract: Disclosed is to a process for manufacturing a cheese product whose fat content is less than or equal to 5% by weight relative to the total weight of the cheese product, having a moisture of the fat-reduced cheese product of 60 to 75% by weight of the total weight of the cheese product. Also disclosed is a cheese product having a moisture of the fat-reduced cheese product of 60 to 75% of the total weight of the cheese product and including at least one protein material in an amount sufficient for the protein content to represent 10 to 35%, the material protein including at least one protein material of dairy origin, at most 5% of fat and supplemental water up to 100%.

Abstract: Resonance energy transfer (RET)- or protein-fragment complement assay (PCA)-based biosensors useful for assessing the activity of G-proteins are described. These biosensors are based on the competition between the G? subunit and a G?? interacting protein (?? IP) for the binding to the G?? dimer. These biosensors comprises (1) a ?? IP and (2) a G? or G? protein; a GPCR; or a plasma membrane targeting domain, fused to suitable RET or PCA tags. Methods using such biosensors for different applications, including the identification of agents that modulates G-protein activity or for the characterization of GPCR signaling/regulation, such as G-protein preferences and activation profiles of GPCRs, are also described.

Abstract: A multipurpose connector for connecting a multiplicity of lines of an aircraft monument. The multipurpose connector comprises a base bracket, a system connector plate configured to receive a multiplicity of first line adapters, a monument connector plate configured to receive at least one second line adapter, and a movement device configured to move the system connector plate relative to the base bracket and the monument connector plate between an open position and a closed position. The system connector plate is, in the closed position, arranged relative to the monument connector plate such that the at least one second line adapter of the monument connector plate is operatively connected to an associated first line adapter of the system connector plate, and, in the open position of the system connector plate, the multiplicity of first line adapters and the at least one second line adapter are detached from one another.

Abstract: Systems and methods for the monitoring of G protein activation at various cell compartments, such as the plasma membrane and the endosomes, and in a G? protein subunit family-selective manner are described. These systems and methods also allows the monitoring of G protein-coupled receptor (GPCR)-mediated as well as non-receptor guanine nucleotide exchange factor (GEF)-mediated G protein activation, and are based on the use of the G protein-binding domains of specific effectors of G proteins and cellular compartment markers, tagged with suitable energy (BRET) donors and acceptors.

Abstract: Bioluminescence resonance energy transfer (BRET) biosensors for assessing the intracellular localization, internalization and trafficking into cellular compartments of proteins such as receptors, and other biomolecules such as second messengers, are disclosed. These biosensors, which are dependent on the concentration/density of the BRET donor and acceptor in cellular compartments rather that specific protein-protein interactions, use a Renilla GFP/Luc BRET pair, which allows the robust and reproducible monitoring of protein trafficking/localization, with a sensitivity compatible with high-throughput screening (HTS). The use of these biosensors for various applications, including assessing/monitoring protein endocytosis, recycling and intracellular trafficking, receptor maturation/rescue by pharmacological chaperones, various endocytosis/exocytosis processes, activation/inhibition, as well as biomolecule concentration/density in different cellular compartments, is also disclosed.

Abstract: Provided herein is a method for identifying a sequence variant in an enriched sample. In certain embodiments, this method may comprise: (a) obtaining: (i) a plurality of sequence reads from a sample that has been enriched for a genomic region and (ii) a reference sequence for the genomic region; (b) assembling the sequence reads to obtain a plurality of discrete sequence assemblies that correspond to potential variants; (c) determining which of the potential variants are true and which are artifacts by examining the sequence reads that make up each of the discrete sequence assemblies; (d) optionally determining whether each of the true potential variants contains a mutation that is known to be associated with the reference sequence; and (e) outputting a report indicating whether the sample comprises a sequence variant.

Abstract: Bioluminescence resonance energy transfer (BRET) biosensors for assessing the intracellular localization, internalization and trafficking into cellular compartments of proteins such as receptors, and other biomolecules such as second messengers, are disclosed. These biosensors, which are dependent on the concentration/density of the BRET donor and acceptor in cellular compartments rather that specific protein-protein interactions, use a Renilla GFP/Luc BRET pair, which allows the robust and reproducible monitoring of protein trafficking/localization, with a sensitivity compatible with high-throughput screening (HTS). The use of these biosensors for various applications, including assessing/monitoring protein endocytosis, recycling and intracellular trafficking, receptor maturation/rescue by pharmacological chaperones, various endocytosis/exocytosis processes, activation/inhibition, as well as biomolecule concentration/density in different cellular compartments, is also disclosed.

Abstract: Disclosed is to a process for manufacturing a cheese product whose fat content is less than or equal to 5% by weight relative to the total weight of the cheese product, having a moisture of the fat-reduced cheese product of 60 to 75% by weight of the total weight of the cheese product. Also disclosed is a cheese product having a moisture of the fat-reduced cheese product of 60 to 75% of the total weight of the cheese product and including at least one protein material in an amount sufficient for the protein content to represent 10 to 35%, the material protein including at least one protein material of dairy origin, at most 5% of fat and supplemental water up to 100%.

Abstract: Aspects of the present innovations relate to systems and/or methods involving multimedia modules, objects or animations. According to an illustrative implementation, one method may include accepting at least one input keyword relating to a subject for the animation and performing processing associated with templates. Further, templates may generates different types of output, and each template may include components for display time, screen location, and animation parameters. Other aspects of the innovations may involve providing search results, retrieving data from a plurality of web sites or data collections, assembling information into multimedia modules or animations, and/or providing module or animation for playback.

Abstract: Bioluminescence resonance energy transfer (BRET) biosensors for assessing the intracellular localization, internalization and trafficking into cellular compartments of proteins such as receptors, and other biomolecules such as second messengers, are disclosed. These biosensors, which are dependent on the concentration/density of the BRET donor and acceptor in cellular compartments rather that specific protein-protein interactions, use a Renilla GFP/Luc BRET pair, which allows the robust and reproducible monitoring of protein trafficking/localization, with a sensitivity compatible with high-throughput screening (HTS). The use of these biosensors for various applications, including assessing/monitoring protein endocytosis, recycling and intra-cellular trafficking, receptor maturation/rescue by pharmacological chaperones, various endocytosis/exocytosis processes, activation/inhibition, as well as biomolecule concentration/density in different cellular compartments, is also disclosed.

Abstract: Resonance energy transfer (RET)- or protein-fragment complement assay (PCA)-based biosensors useful for assessing the activity of G-proteins are described. These biosensors are based on the competition between the Got subunit and a G?? interacting protein (?? IP) for the binding to the G?? dimer. These biosensors comprises (1) a ?? IP and (2) a G? or G? protein; a GPCR; or a plasma membrane targeting domain, fused to suitable RET or PCA tags. Methods using such biosensors for different applications, including the identification of agents that modulates G-protein activity or for the characterization of GPCR signaling/regulation, such as G-protein preferences and activation profiles of GPCRs, are also described.

Abstract: Aspects of the present innovations relate to systems and/or methods involving multimedia modules, objects or animations. According to an illustrative implementation, one method may include accepting at least one input keyword relating to a subject for the animation and performing processing associated with templates. Further, templates may generates different types of output, and each template may include components for display time, screen location, and animation parameters. Other aspects of the innovations may involve providing search results, retrieving data from a plurality of web sites or data collections, assembling information into multimedia modules or animations, and/or providing module or animation for playback.

Abstract: Aspects of the present innovations relate to systems and/or methods involving multimedia modules, objects or animations. According to an illustrative implementation, one method may include accepting at least one input keyword relating to a subject for the animation and performing processing associated with templates. Further, templates may generates different types of output, and each template may include components for display time, screen location, and animation parameters. Other aspects of the innovations may involve providing search results, retrieving data from a plurality of web sites or data collections, assembling information into multimedia modules or animations, and/or providing module or animation for playback.

Abstract: Aspects of the present innovations relate to systems and/or methods involving multimedia modules, objects or animations. According to an illustrative implementation, one method may include accepting at least one input keyword relating to a subject for the animation and performing processing associated with templates. Further, templates may generates different types of output, and each template may include components for display time, screen location, and animation parameters. Other aspects of the innovations may involve providing search results, retrieving data from a plurality of web sites or data collections, assembling information into multimedia modules or animations, and/or providing module or animation for playback.

Abstract: Provided herein, among other things, is a computer-implemented method for assigning a sequence read to a genomic location, the method including: a) accessing a file containing a sequence read, wherein the sequence read is obtained from a nucleic acid sample that has been enriched by hybridization to a plurality of capture sequences; and b) assigning the sequence read to a genomic location by: i) identifying a capture sequence as being a match with the sequence read if the sequence read contains one or more subsequences of the capture sequence; ii) calculating, using a computer, a score indicating the degree of sequence similarity between each of the matched capture sequences and the sequence read; and iii) assigning the sequence read to the genomic location if the calculated score for a matched capture sequence is above a threshold.